Pharmaceutical Gases

1. Physical & Chemical Properties
& Uses Of Pharmaceutical &
Medicinal Gas
By Zisan Ahmed Ziko

3. GAS
Gas is one of the four
fundamental states of
matter.

4. Example of gases
 Oxygen
 Nitrogen
 Carbon Dioxide
 Florine
 Hydrogen

5. Pharmaceutical Gas
 The gas which are used in
pharmaceutical industry is
called the pharmaceutical
gas.

6. Example of
Pharmaceutical Gas :
 Nitrogen
 Oxygen
 Carbon Dioxide
 Ozone
 Hydroge

7.  Physical Properties Of
Pharmaceutical gas

8. Nitrogen:
 Nitrogen gas is generally inert.
 It is a colorless gas.
 It has no Taste.
 Melting point -210° C
 Boiling point -196° C

9. Oxygen
 Oxygen exists in all three forms - liquid, solid, and gas.
 oxygen gas is colourless,
 Tasteless.
 Boiling point -182.96°C
 Melting point -218.4°C.

10. Carbon Dioxide
 Carbon dioxide is a colourless gas.
 It is soluble in water .
 Melting Point : -55.6 degC
 Boiling Point : -78.5 degC
 Density : 1.977

11.  Chemical Properties Of
Pharmaceutical gas

12. Nitrogen
 The color of indicators is not affected by the Nitrogen.
 Nitrogen can combine with other elements .
 At high temperature or low temperature nitrogen can
form compounds.

13. Oxygen
 it supports combustion.
 Oxygen also combines with elements
at room temperature.
 Oxygen also reacts with many
compounds.

14. Carbon Dioxide
 Carbon dioxide is a linear covalent molecule.
 Carbon dioxide is an acidic oxide and reacts with water
to give carbonic acid.
CO2 + H2O ==> H2CO3

15. Uses of pharmaceutical gas
Nitrogen:
Nitrogen is used for
 Inerting
 Lyophilisation
 Drying
 Liquid phase transfer
Oxygen
Oxygen is Used for
 Chemical synthesis
 Low temperature storage
 Cyro condensation of waste gases
 In fermentation

16.  Ozone :
 Used in chemical synthesis
 Uses in cyro grinding
 Low temperature storage
 Carbon Dioxide :
It is used for
 Inerting
 Chemical synthesis
 Extration
 Transportation of products

17. Medicinal Gas
Medical gases fall the definition of drugs
and such must be treated as
pharmaceutical products

18. Example
Helium
Nitrogen
Nitrous Oxide
Halothane
Oxygen
Calibration of devices
Carbon Dioxide

19. Physical Properties Of
Medicinal Gas

20. Xenon
 Xenon is a colorless.
 It is odourless gas.
 It has a boiling point of -108.13°C (-162.5°F)

21. Nirous Oxide
 Color: colorless
 Odor: slightly sweet
 melting point -90.81 oC
 boiling point -88.46 oC

22. Helium
 Helium is a colorless.
 It is odorless.
 It is a tasteless gas.
 Boiling point -268.9°C
 The freezing point of helium is -272.2°C

23. Chemical properties of
Medicinal gases

24. Helium
 It is less soluble in water than any
other gas.
 It is non toxic.
 It is non-flammable

25. Nitrous Oxide
 It is highly soluble in alcohol, ether, oils, and
sulfuric acid.
 By heating ammonium nitrate, it will
decompose into nitrous oxide and water vapor
(NH4NO3 (s) → 2 H2O (g) + N2O (g)).

26.  Hydrogen:
This gas is used in chemical synthesis and
biochemistry.
Ammonia:
This gas is used in chemical synthesis and
biochemistry.
Nitrous Oxide :Used as gas propeilant for aerosois
packaging

27. Uses of medicinal gas
Carbon dioxide :
 Carbon dioxide in liquid phase provides temperatures of
down to -76.C and can therefore
 It can be used for cryotherapy for local analgesia.
Helium :
 Liquid helium is used to cool the magnets.
 It also used in modern Magnetic Resonanace.

28. Nitrogen : It is used for
 cryobiology
 crytherapy.
Nitrous oxide :
 N2O is used for introduction and maintenance of
inhalational anesthesia in combination with other drugs
such as volatile compounds,anesthetics,muscle relaxants
analgesic compouns and others.
Oxygen :
 As oxygen is essential for life.Therefore oxygen is given for
treatment and prevention of a variety of cardiac pulmonary
and other diseases.