Brain drain means the transfer of talents from a less developed country to a developed one through temporary or permanent migration. This phenomenon takes place across the continents characterized by South-to-North migration, chained or permanent migrations are inevitably hindering the development of countries of origin by vacuuming the talents who have been nurtured and educated there throughout their youths, leading to an indirectly net transfer of capitals from a poorer country to a well-off one. Recognizing the inherent gap between Southern and Northern countries in economy and social stability, the slides show how brain drain can be utilized constructively and how the fundamental weaknesses of less developed countries can be tackled. Politically, Southern countries should strive for enhancing national security and formulating measures to tackle local issues such as corruption and democracy; secondly, clear direction of development is indispensible to especially propagandize to attract migrants and foreign investments, frequent connections with emigrants can definitely fuel the effectiveness; in the area of localism, national consciousness and cultural attractions are key elements in promoting return migration or even north-to-south migration, that is, making the country livable, vibrant, attractive and comfortable to stay and work.