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ALTERED CONSCIOUSNESS
GENERAL CONSIDERATIONS





Terms
Confusion intermingling of ideas
Delirium illusions ,delusions
Dizziness
a disturbed sense of relationship to space
unsteady-------

Causes

drug overdose…..alcohol……local anesthesia, sedat…

Hyperventilation

Hypoglycemia

Hyperglycemia

Hypothyroidism

Hyperthyroidism

cerebr vasc acc

ALTERED CONSCIOUSNESS
Confusion intermingling of ideas
Delirium illusions ,delusions
Dizziness
a disturbed sense of relationship to space
unsteady-------
Predisposing factors
Drugs
alcohol;
local anesth sed,
 Hyperventilation
 Diabetes mellitus
 Thyroid gland dysfunctions

prevention
Early recognition
 Avoid drugs
 medical history
 clinical exam

Clin manif


Depend on cause

in Hyperventilation: rapid respir rate
 in Hypoglycemia
: cold wet skin
 in Hyperglycemia : hot dry skin


in Hypothyroidism: weakness fatigue
 in Hyperthyroidism : restlessness
 in cerebr vasc acc: sudden loss of consc

management
1-Recognize
 2- terminate dental procedure
 3-P-----depend on cause

supine position is accepitable…….

in diabetic & thyroid dis--- upright

in cerebrovasc acc---- can upright to dec bl pr
 3- A

B

C
 4-definitive care

m- monitor vital signs

m- manage signs & symptom

d-defin tt depend on cause

DIABETES MELLITUS [dm.]
Definition

a disorder of glucose metabolism --
hyperglycemia due to decr insulin secretion
or decr its activity or both
 Normal glucose level

80----100 mg /100ml blood

decr 50 mg------------hypoglyc in adults

decr 40 mg-----------hypoglyc in children

Fasting
glucose
level
complication
Acute complications
hypoglycemic coma….more acute& danger
hyperglycemic coma….less acute & ??
 chronic complications
Affecting large bl vessels------arteriosclerosis
Affecting small bl vessels--- microangiopathy
Affecting interstit tissue…..incr infections
periodontal infections

Affecting large bl vessels-----arteriosclerosis
Affecting small bl vessels--microangiopathy
Affecting interstit tissue…..
infections
Predisposing factors
Genetic factor

if both parent --------100%offsprings
 Disorders destroying islets of langerhans
 Other endocrine dysfunctions

corticost ttt ----iatrogenic diabetes

Classification of diabetes
Depending on age

adult onset DM

juvenile onset DM
 Depending on insulin injections

insulin dependent DM

non insulin dependent DM
 NOW we have these types

Type I DM
 Type II DM
 Impaired glucose tolerance I G T
 Impaired fasting glucose I F G
 Gestational diabetes

Type I, juvenile, IDDM
Genetically determined
8%
 Usually start in young
 There is no insulin in pat blood ie
[ insulinopenic]

glucagon is high

pancreatic B-cells are non responsive

Genetically determined
8%
Usually start in young
There is no insulin in pat blood ie
[ insulinopenic]
glucagon is high
pancreatic B-cells are non
responsive
GENETICALLY
human lymphocytic antigens on the
lymphocytes determined by chromosome
6 are impaired
 Immunologically
may autoimmune response as there
are antibodies…
 Other causes infect, drugs

Type II, adult, NIDDM
milder
 80 %
 Usually start in adults
 There are enough insulin [ to avoid
ketoacidosis]
 usually don’t need exogenous insulin










May be duo to lack of insulin receptors in
peripheral tissues
is divided into
Non obese type
Obese type
Non obese

obese
Clinical manifestations
D M ----- may be presented as
hyperglycemia
or hypoglycemia
NB hypoglycemia is more dangerous
D M ----- may be presented as
one or more of its complications



In hyperglycemia

There is syndrome of poly
polyurea, polydipsia ,polyphagia
,blurred vision ,pruritus….
 Start by nocturnal enuresis with loss of w --coma
 Other S/S…..

Hyper
glycemia


In hypoglycemia

In Early –CNS : hunger, nausea, hyperactive
 In Moderate--- adrenaline is released...>


sweating ,bizarre behavioral patterns
 In severe: unconsc, seizures ,hypotention
&hypothermia
 Acute complications are common

hypoglycemia
Control of DM
Self monitoring
 Diet control
 Physical activity
 Oral hypoglycemic drugs

a)sulfonyureas

tolbutamide

Glyburide

b)biguanide metformin
 Insulin treatment
Prevention
Preliminary patient evaluation
 Physical exam
 DENTAL observations

-if any doubt--- physician

Type II can tolerate dental care

Type I should be cared
 Observe ttt & complications
 Adjust dose of local anesth, insulin

Diabetic patients can tolerate
hyperglycemia more than hypoglycemia
 So after extensive dental procedures

type I DM ---check blood
glucose level in the next few days….

Antibiotic cover is important

management












I- recognition
Sign & sy of hypoglycemia
early: hunger ,nausea, Weakness & dizziness
moderate :[adren rel],hot moist Pale skin
late : anxiety , Headache
Altered consc
Sign & sy of hyperglycemia…..poly syndrome…
blood glucose > 250 [non fasting]
Acidosis ph < 7.3
Dry [loss of water],warm skin
Abnormal respir [ Kussmaul’s ]
Rapid weak pulse
Altered consc
D/D hypoglycemia &hyperglycemia









In hypoglycemia
onset : rapid [ min]
Skin
: cold & wet
Breath : no odour
In hyperglycemia
onset
: slow [ hours & days ]
Skin
: hot & dry
Breath : acetone




If still in doubt----------apply PABC till medical assist
DM patient with imp consc should be managed as
having hypoglycemia until proved otherwise
Manag of hypogly a-consc
1-recognition of hypoglycemia
 2-terminate dent proc
 3-p
 4-A, B,C
 5-definitive care

oral CHO

orange juice
 6- recovery

observe for at least 1h

Manag of hypogly b-unconsc













1- no time for recognition of hypoglycemia
2-terminate dent proc
3-p
4-A, B,C
5-definitive care
summoning of medical assistance
IV CHO
50% dextrose
1mg glucagon
.5mg epinephrine
6- recovery
oral CHO after recovery
Manag of hypergly a-consc
1-recognition of hyperglycemia
 2-avoid any dental pro & terminate any
one

Manag of hypergly b-unconsc













1-R
2-terminate dent proc
3-p
4-A, B,C
7-definitive care
medical assistance
IV CHO
5% , 5% , 5% . 5% . 5% dextrose
?? insulin in emergency
give O
8- transport to hospital

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Altered consciousness

  • 2. GENERAL CONSIDERATIONS     Terms Confusion intermingling of ideas Delirium illusions ,delusions Dizziness a disturbed sense of relationship to space unsteady------- Causes  drug overdose…..alcohol……local anesthesia, sedat…  Hyperventilation  Hypoglycemia  Hyperglycemia  Hypothyroidism  Hyperthyroidism  cerebr vasc acc 
  • 3. ALTERED CONSCIOUSNESS Confusion intermingling of ideas Delirium illusions ,delusions Dizziness a disturbed sense of relationship to space unsteady-------
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  • 5. Predisposing factors Drugs alcohol; local anesth sed,  Hyperventilation  Diabetes mellitus  Thyroid gland dysfunctions 
  • 6. prevention Early recognition  Avoid drugs  medical history  clinical exam 
  • 7. Clin manif  Depend on cause in Hyperventilation: rapid respir rate  in Hypoglycemia : cold wet skin  in Hyperglycemia : hot dry skin  in Hypothyroidism: weakness fatigue  in Hyperthyroidism : restlessness  in cerebr vasc acc: sudden loss of consc 
  • 8. management 1-Recognize  2- terminate dental procedure  3-P-----depend on cause  supine position is accepitable…….  in diabetic & thyroid dis--- upright  in cerebrovasc acc---- can upright to dec bl pr  3- A  B  C  4-definitive care  m- monitor vital signs  m- manage signs & symptom  d-defin tt depend on cause 
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  • 10. DIABETES MELLITUS [dm.] Definition  a disorder of glucose metabolism -- hyperglycemia due to decr insulin secretion or decr its activity or both  Normal glucose level  80----100 mg /100ml blood  decr 50 mg------------hypoglyc in adults  decr 40 mg-----------hypoglyc in children 
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  • 13. complication Acute complications hypoglycemic coma….more acute& danger hyperglycemic coma….less acute & ??  chronic complications Affecting large bl vessels------arteriosclerosis Affecting small bl vessels--- microangiopathy Affecting interstit tissue…..incr infections periodontal infections 
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  • 15. Affecting large bl vessels-----arteriosclerosis Affecting small bl vessels--microangiopathy Affecting interstit tissue….. infections
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  • 27. Predisposing factors Genetic factor  if both parent --------100%offsprings  Disorders destroying islets of langerhans  Other endocrine dysfunctions  corticost ttt ----iatrogenic diabetes 
  • 28. Classification of diabetes Depending on age  adult onset DM  juvenile onset DM  Depending on insulin injections  insulin dependent DM  non insulin dependent DM  NOW we have these types 
  • 29.
  • 30. Type I DM  Type II DM  Impaired glucose tolerance I G T  Impaired fasting glucose I F G  Gestational diabetes 
  • 31. Type I, juvenile, IDDM Genetically determined 8%  Usually start in young  There is no insulin in pat blood ie [ insulinopenic]  glucagon is high  pancreatic B-cells are non responsive 
  • 32. Genetically determined 8% Usually start in young There is no insulin in pat blood ie [ insulinopenic] glucagon is high pancreatic B-cells are non responsive
  • 33. GENETICALLY human lymphocytic antigens on the lymphocytes determined by chromosome 6 are impaired  Immunologically may autoimmune response as there are antibodies…  Other causes infect, drugs 
  • 34. Type II, adult, NIDDM milder  80 %  Usually start in adults  There are enough insulin [ to avoid ketoacidosis]  usually don’t need exogenous insulin  
  • 35.     May be duo to lack of insulin receptors in peripheral tissues is divided into Non obese type Obese type
  • 37. Clinical manifestations D M ----- may be presented as hyperglycemia or hypoglycemia NB hypoglycemia is more dangerous D M ----- may be presented as one or more of its complications 
  • 38.  In hyperglycemia There is syndrome of poly polyurea, polydipsia ,polyphagia ,blurred vision ,pruritus….  Start by nocturnal enuresis with loss of w --coma  Other S/S….. 
  • 40.  In hypoglycemia In Early –CNS : hunger, nausea, hyperactive  In Moderate--- adrenaline is released...>  sweating ,bizarre behavioral patterns  In severe: unconsc, seizures ,hypotention &hypothermia  Acute complications are common 
  • 42. Control of DM Self monitoring  Diet control  Physical activity  Oral hypoglycemic drugs  a)sulfonyureas  tolbutamide  Glyburide  b)biguanide metformin  Insulin treatment
  • 43. Prevention Preliminary patient evaluation  Physical exam  DENTAL observations  -if any doubt--- physician  Type II can tolerate dental care  Type I should be cared  Observe ttt & complications  Adjust dose of local anesth, insulin 
  • 44. Diabetic patients can tolerate hyperglycemia more than hypoglycemia  So after extensive dental procedures  type I DM ---check blood glucose level in the next few days….  Antibiotic cover is important 
  • 45. management          I- recognition Sign & sy of hypoglycemia early: hunger ,nausea, Weakness & dizziness moderate :[adren rel],hot moist Pale skin late : anxiety , Headache Altered consc Sign & sy of hyperglycemia…..poly syndrome… blood glucose > 250 [non fasting] Acidosis ph < 7.3 Dry [loss of water],warm skin Abnormal respir [ Kussmaul’s ] Rapid weak pulse Altered consc
  • 46. D/D hypoglycemia &hyperglycemia         In hypoglycemia onset : rapid [ min] Skin : cold & wet Breath : no odour In hyperglycemia onset : slow [ hours & days ] Skin : hot & dry Breath : acetone   If still in doubt----------apply PABC till medical assist DM patient with imp consc should be managed as having hypoglycemia until proved otherwise
  • 47. Manag of hypogly a-consc 1-recognition of hypoglycemia  2-terminate dent proc  3-p  4-A, B,C  5-definitive care  oral CHO  orange juice  6- recovery  observe for at least 1h 
  • 48. Manag of hypogly b-unconsc             1- no time for recognition of hypoglycemia 2-terminate dent proc 3-p 4-A, B,C 5-definitive care summoning of medical assistance IV CHO 50% dextrose 1mg glucagon .5mg epinephrine 6- recovery oral CHO after recovery
  • 49. Manag of hypergly a-consc 1-recognition of hyperglycemia  2-avoid any dental pro & terminate any one 
  • 50. Manag of hypergly b-unconsc             1-R 2-terminate dent proc 3-p 4-A, B,C 7-definitive care medical assistance IV CHO 5% , 5% , 5% . 5% . 5% dextrose ?? insulin in emergency give O 8- transport to hospital