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NCBO Technology 
Trish Whetzel 
Outreach Coordinator 
THE NATIONAL CENTER FOR 
BIOMEDICAL ONTOLOGY
Outline 
• NCBO Overview 
• BioPortal 
• NCBO Web Services 
• Applications using NCBO Technology
National Centers for Biomedical Computing 
(http://www.ncbcs.org)
NCBO Key Activities 
• We create and maintain a library of 
biomedical ontologies 
• We build tools and Web services to 
enable the use of ontologies 
• We collaborate with scientific 
communities that develop and use 
ontologies
www.bioontology.or 
g
Outline 
• NCBO Overview 
• BioPortal 
• NCBO Web Services 
• Applications using NCBO Technology
bbiiooppoorrttaall..bbiioooonnttoollooggyy..oorrgg
BioPortal 
• Repository of biomedical ontologies 
• Stores ontologies developed in OWL or OBO 
format 
• View, browse, and search across ontologies 
through the Web interface 
• Programmatic access to ontologies via Web 
services and SPARQL endpoint 
• Access control for private ontologies
Outline 
• NCBO Overview 
• BioPortal 
• NCBO Web Services 
• Applications using NCBO Technology
http://http://rreesstt..bbiioooonnttoollooggyy..oorrgg 
Ontology 
Services 
Ontology 
Services 
• Search 
• Traverse 
• Comment 
• Download 
• Search 
• Traverse 
• Comment 
• Download 
Mapping 
Services 
Mapping 
Services 
WWididggeettss 
• Create 
• Upload 
• Download 
• Tree-view 
• Auto-complete 
• Graph-view 
• Tree-view 
• Auto-complete 
• Graph-view 
AAnnnnoottaattioionn 
DDaattaa A Acccceessss 
• Create 
• Upload 
• Download 
TTeerrmm r reeccooggnnititioionn 
Search “data” 
annotated with a 
given term 
Search “data” 
annotated with a 
given term 
hhttttpp::////bbiiooppoorrttaall..bbiioooonnttoollooggyy..oorrgg
Outline 
• NCBO Overview 
• BioPortal 
• NCBO Web Services 
• Applications using NCBO Technology
Applications using NCBO Technology
These 3 software 
components of 
use BioPortal Web services 
to access, browse ontology 
and provide term-tagging 
features 
http://isatab.sourceforge.nneett//iissaaccrreeaattoorr..hhttmmll
http://mmeettaaggeennoommiiccss..aannll..ggoovv//
http://ontogrator.oorrgg//cclliinniiccaallttrriiaallss
https://submit.ncbi.nlm.nih.gov/biosample/t 
emplates/all_attributes/
http://biosharing.org/standards/tteerrmmiinnoollooggyy__aarrttiiffaacctt
Summary 
• NCBO provides access to ontologies via Web 
services 
• Web services are easy to integrate into 
software applications 
• Use of common ontologies across projects 
better facilitates data integration and analysis
Thank you! 
• Web service documentation: 
http://www.bioontology.org/wiki/index.php/ 
NCBO_REST_services 
• Keep in touch 
– Software support: 
support@bioontology.org 
–Twitter: @bioontology 
– Facebook: http://on.fb.me/bioontology 
– LinkedIn: http://linkd.in/ncbo-group

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NCBO Technology for GSC15

Editor's Notes

  1. Ontology Development and Visualization Data Annotation Data Integration
  2. Ecosystem revolving around the ISA-TAB format Support for massively parallel datasets Focus on a couple of the tools – OntoMaton Gradient from left to right – configuration (annotation guidelines), curation tools to analysis and usage – people can choose the path that is more convenient for their use case