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Human 
Anatomy 
& Physiology 
SEVENTH EDITION 
Elaine N. Marieb 
Katja Hoehn 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
PowerPoint® Lecture Slides 
prepared by Vince Austin, 
Bluegrass Technical 
and Community College 
C H A P T E R 6Bones and 
Skeletal 
Tissues 
P A R T A
Skeletal Cartilage 
 Contains no blood vessels or nerves 
 Surrounded by the perichondrium (dense irregular 
connective tissue) that resists outward expansion 
 Three types – hyaline, elastic, and fibrocartilage 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Hyaline Cartilage 
 Provides support, flexibility, and resilience 
 Is the most abundant skeletal cartilage 
 Is present in these cartilages: 
 Articular – covers the ends of long bones 
 Costal – connects the ribs to the sternum 
 Respiratory – makes up larynx, reinforces air 
passages 
 Nasal – supports the nose 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Elastic Cartilage 
 Similar to hyaline cartilage, but contains elastic 
fibers 
 Found in the external ear and the epiglottis 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Fibrocartilage 
 Highly compressed with great tensile strength 
 Contains collagen fibers 
 Found in menisci of the knee and in intervertebral 
discs 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Growth of Cartilage 
 Appositional – cells in the perichondrium secrete 
matrix against the external face of existing 
cartilage 
 Interstitial – lacunae-bound chondrocytes inside 
the cartilage divide and secrete new matrix, 
expanding the cartilage from within 
 Calcification of cartilage occurs 
 During normal bone growth 
 During old age 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bones and Cartilages of the Human Body 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.1
Classification of Bones 
 Axial skeleton – bones of the skull, vertebral 
column, and rib cage 
 Appendicular skeleton – bones of the upper and 
lower limbs, shoulder, and hip 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Classification of Bones: By Shape 
 Long bones – 
longer than 
they are wide 
(e.g., humerus) 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.2a
Classification of Bones: By Shape 
 Short bones 
 Cube-shaped 
bones of the 
wrist and 
ankle 
 Bones that 
form within 
tendons (e.g., 
patella) 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.2b
Classification of Bones: By Shape 
 Flat bones – 
thin, flattened, 
and a bit 
curved (e.g., 
sternum, and 
most skull 
bones) 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.2c
Classification of Bones: By Shape 
 Irregular 
bones – 
bones with 
complicated 
shapes (e.g., 
vertebrae and 
hip bones) 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.2d
Function of Bones 
 Support – form the framework that supports the 
body and cradles soft organs 
 Protection – provide a protective case for the brain, 
spinal cord, and vital organs 
 Movement – provide levers for muscles 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Function of Bones 
 Mineral storage – reservoir for minerals, especially 
calcium and phosphorus 
 Blood cell formation – hematopoiesis occurs 
within the marrow cavities of bones 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Markings 
 Bulges, depressions, and holes that serve as: 
 Sites of attachment for muscles, ligaments, and 
tendons 
 Joint surfaces 
 Conduits for blood vessels and nerves 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Markings: Projections – 
Sites of Muscle and Ligament Attachment 
 Tuberosity – rounded projection 
 Crest – narrow, prominent ridge of bone 
 Trochanter – large, blunt, irregular surface 
 Line – narrow ridge of bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Markings: Projections – 
Sites of Muscle and Ligament Attachment 
 Tubercle – small rounded projection 
 Epicondyle – raised area above a condyle 
 Spine – sharp, slender projection 
 Process – any bony prominence 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Markings: Projections – 
Projections That Help to Form Joints 
 Head – bony expansion carried on a narrow neck 
 Facet – smooth, nearly flat articular surface 
 Condyle – rounded articular projection 
 Ramus – armlike bar of bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Markings: Depressions and Openings 
 Meatus – canal-like passageway 
 Sinus – cavity within a bone 
 Fossa – shallow, basin-like depression 
 Groove – furrow 
 Fissure – narrow, slit-like opening 
 Foramen – round or oval opening through a bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Gross Anatomy of Bones: Bone Textures 
 Compact bone – dense outer layer 
 Spongy bone – honeycomb of trabeculae filled 
with yellow bone marrow 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Markings 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Table 6.1
Structure of Long Bone 
 Long bones consist of a diaphysis and an epiphysis 
 Diaphysis 
 Tubular shaft that forms the axis of long bones 
 Composed of compact bone that surrounds the 
medullary cavity 
 Yellow bone marrow (fat) is contained in the 
medullary cavity 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Structure of Long Bone 
 Epiphyses 
 Expanded ends of long bones 
 Exterior is compact bone, and the interior is 
spongy bone 
 Joint surface is covered with articular (hyaline) 
cartilage 
 Epiphyseal line separates the diaphysis from the 
epiphyses 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Structure of Long Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.3
Structure of Long Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.3a
Structure of Long Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.3b
Structure of Long Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.3c
Bone Membranes 
 Periosteum – double-layered protective membrane 
 Outer fibrous layer is dense regular connective 
tissue 
 Inner osteogenic layer is composed of osteoblasts 
and osteoclasts 
 Richly supplied with nerve fibers, blood, and 
lymphatic vessels, which enter the bone via 
nutrient foramina 
 Secured to underlying bone by Sharpey’s fibers 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Membranes 
 Endosteum – delicate membrane covering internal 
surfaces of bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Structure of Short, Irregular, and Flat Bones 
 Thin plates of periosteum-covered compact bone 
on the outside with endosteum-covered spongy 
bone (diploë) on the inside 
 Have no diaphysis or epiphyses 
 Contain bone marrow between the trabeculae 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Structure of a Flat Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.4
Location of Hematopoietic Tissue 
(Red Marrow) 
 In infants 
 Found in the medullary cavity and all areas of 
spongy bone 
 In adults 
 Found in the diploë of flat bones, and the head of 
the femur and humerus 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Microscopic Structure of Bone: 
Compact Bone 
 Haversian system, or osteon – the structural unit of 
compact bone 
 Lamella – weight-bearing, column-like matrix 
tubes composed mainly of collagen 
 Haversian, or central canal – central channel 
containing blood vessels and nerves 
 Volkmann’s canals – channels lying at right angles 
to the central canal, connecting blood and nerve 
supply of the periosteum to that of the Haversian 
canal 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Microscopic Structure of Bone: 
Compact Bone 
 Osteocytes – mature bone cells 
 Lacunae – small cavities in bone that contain 
osteocytes 
 Canaliculi – hairlike canals that connect lacunae to 
each other and the central canal 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Microscopic Structure of Bone: Compact 
Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.6a, b
Microscopic Structure of Bone: Compact 
Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.6a
Microscopic Structure of Bone: Compact 
Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.6b
Microscopic Structure of Bone: Compact 
Bone 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 6.6c
Chemical Composition of Bone: Organic 
 Osteoblasts – bone-forming cells 
 Osteocytes – mature bone cells 
 Osteoclasts – large cells that resorb or break down 
bone matrix 
 Osteoid – unmineralized bone matrix composed of 
proteoglycans, glycoproteins, and collagen 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Chemical Composition of Bone: Inorganic 
 Hydroxyapatites, or mineral salts 
 Sixty-five percent of bone by mass 
 Mainly calcium phosphates 
 Responsible for bone hardness and its resistance to 
compression 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
 Hydroxylapatite, also called hydroxyapatite 
(HA), is a naturally occurring mineral form of 
calcium apatite with the formula Ca5(PO4)3(OH), 
but is usually written Ca10(PO4)6(OH)2 to denote that 
the crystal unit cell comprises two entities. 
Hydroxylapatite is the hydroxyl endmember of the 
complex apatite group. The OH- ion can be 
replaced by fluoride, chloride or carbonate, 
producing fluorapatite or chlorapatite. fluorosis. 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Bone Development 
 Osteogenesis and ossification – the process of bone 
tissue formation, which leads to: 
 The formation of the bony skeleton in embryos 
 Bone growth until early adulthood 
 Bone thickness, remodeling, and repair 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Formation of the Bony Skeleton 
 Begins at week 8 of embryo development 
 Intramembranous ossification – bone develops 
from a fibrous membrane 
 Endochondral ossification – bone forms by 
replacing hyaline cartilage 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Intramembranous Ossification 
 Formation of most of the flat bones of the skull and 
the clavicles 
 Fibrous connective tissue membranes are formed 
by mesenchymal cells 
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings

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Ch06 a.bone

  • 1. Human Anatomy & Physiology SEVENTH EDITION Elaine N. Marieb Katja Hoehn Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint® Lecture Slides prepared by Vince Austin, Bluegrass Technical and Community College C H A P T E R 6Bones and Skeletal Tissues P A R T A
  • 2. Skeletal Cartilage  Contains no blood vessels or nerves  Surrounded by the perichondrium (dense irregular connective tissue) that resists outward expansion  Three types – hyaline, elastic, and fibrocartilage Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 3. Hyaline Cartilage  Provides support, flexibility, and resilience  Is the most abundant skeletal cartilage  Is present in these cartilages:  Articular – covers the ends of long bones  Costal – connects the ribs to the sternum  Respiratory – makes up larynx, reinforces air passages  Nasal – supports the nose Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 4. Elastic Cartilage  Similar to hyaline cartilage, but contains elastic fibers  Found in the external ear and the epiglottis Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 5. Fibrocartilage  Highly compressed with great tensile strength  Contains collagen fibers  Found in menisci of the knee and in intervertebral discs Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 6. Growth of Cartilage  Appositional – cells in the perichondrium secrete matrix against the external face of existing cartilage  Interstitial – lacunae-bound chondrocytes inside the cartilage divide and secrete new matrix, expanding the cartilage from within  Calcification of cartilage occurs  During normal bone growth  During old age Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 7. Bones and Cartilages of the Human Body Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.1
  • 8. Classification of Bones  Axial skeleton – bones of the skull, vertebral column, and rib cage  Appendicular skeleton – bones of the upper and lower limbs, shoulder, and hip Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 9. Classification of Bones: By Shape  Long bones – longer than they are wide (e.g., humerus) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.2a
  • 10. Classification of Bones: By Shape  Short bones  Cube-shaped bones of the wrist and ankle  Bones that form within tendons (e.g., patella) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.2b
  • 11. Classification of Bones: By Shape  Flat bones – thin, flattened, and a bit curved (e.g., sternum, and most skull bones) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.2c
  • 12. Classification of Bones: By Shape  Irregular bones – bones with complicated shapes (e.g., vertebrae and hip bones) Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.2d
  • 13. Function of Bones  Support – form the framework that supports the body and cradles soft organs  Protection – provide a protective case for the brain, spinal cord, and vital organs  Movement – provide levers for muscles Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 14. Function of Bones  Mineral storage – reservoir for minerals, especially calcium and phosphorus  Blood cell formation – hematopoiesis occurs within the marrow cavities of bones Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 15. Bone Markings  Bulges, depressions, and holes that serve as:  Sites of attachment for muscles, ligaments, and tendons  Joint surfaces  Conduits for blood vessels and nerves Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 16. Bone Markings: Projections – Sites of Muscle and Ligament Attachment  Tuberosity – rounded projection  Crest – narrow, prominent ridge of bone  Trochanter – large, blunt, irregular surface  Line – narrow ridge of bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 17. Bone Markings: Projections – Sites of Muscle and Ligament Attachment  Tubercle – small rounded projection  Epicondyle – raised area above a condyle  Spine – sharp, slender projection  Process – any bony prominence Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 18. Bone Markings: Projections – Projections That Help to Form Joints  Head – bony expansion carried on a narrow neck  Facet – smooth, nearly flat articular surface  Condyle – rounded articular projection  Ramus – armlike bar of bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 19. Bone Markings: Depressions and Openings  Meatus – canal-like passageway  Sinus – cavity within a bone  Fossa – shallow, basin-like depression  Groove – furrow  Fissure – narrow, slit-like opening  Foramen – round or oval opening through a bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 20. Gross Anatomy of Bones: Bone Textures  Compact bone – dense outer layer  Spongy bone – honeycomb of trabeculae filled with yellow bone marrow Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 21. Bone Markings Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Table 6.1
  • 22. Structure of Long Bone  Long bones consist of a diaphysis and an epiphysis  Diaphysis  Tubular shaft that forms the axis of long bones  Composed of compact bone that surrounds the medullary cavity  Yellow bone marrow (fat) is contained in the medullary cavity Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 23. Structure of Long Bone  Epiphyses  Expanded ends of long bones  Exterior is compact bone, and the interior is spongy bone  Joint surface is covered with articular (hyaline) cartilage  Epiphyseal line separates the diaphysis from the epiphyses Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 24. Structure of Long Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.3
  • 25. Structure of Long Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.3a
  • 26. Structure of Long Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.3b
  • 27. Structure of Long Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.3c
  • 28. Bone Membranes  Periosteum – double-layered protective membrane  Outer fibrous layer is dense regular connective tissue  Inner osteogenic layer is composed of osteoblasts and osteoclasts  Richly supplied with nerve fibers, blood, and lymphatic vessels, which enter the bone via nutrient foramina  Secured to underlying bone by Sharpey’s fibers Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 29. Bone Membranes  Endosteum – delicate membrane covering internal surfaces of bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 30. Structure of Short, Irregular, and Flat Bones  Thin plates of periosteum-covered compact bone on the outside with endosteum-covered spongy bone (diploë) on the inside  Have no diaphysis or epiphyses  Contain bone marrow between the trabeculae Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 31. Structure of a Flat Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.4
  • 32. Location of Hematopoietic Tissue (Red Marrow)  In infants  Found in the medullary cavity and all areas of spongy bone  In adults  Found in the diploë of flat bones, and the head of the femur and humerus Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 33. Microscopic Structure of Bone: Compact Bone  Haversian system, or osteon – the structural unit of compact bone  Lamella – weight-bearing, column-like matrix tubes composed mainly of collagen  Haversian, or central canal – central channel containing blood vessels and nerves  Volkmann’s canals – channels lying at right angles to the central canal, connecting blood and nerve supply of the periosteum to that of the Haversian canal Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 34. Microscopic Structure of Bone: Compact Bone  Osteocytes – mature bone cells  Lacunae – small cavities in bone that contain osteocytes  Canaliculi – hairlike canals that connect lacunae to each other and the central canal Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 35. Microscopic Structure of Bone: Compact Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.6a, b
  • 36. Microscopic Structure of Bone: Compact Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.6a
  • 37. Microscopic Structure of Bone: Compact Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.6b
  • 38. Microscopic Structure of Bone: Compact Bone Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 6.6c
  • 39. Chemical Composition of Bone: Organic  Osteoblasts – bone-forming cells  Osteocytes – mature bone cells  Osteoclasts – large cells that resorb or break down bone matrix  Osteoid – unmineralized bone matrix composed of proteoglycans, glycoproteins, and collagen Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 40. Chemical Composition of Bone: Inorganic  Hydroxyapatites, or mineral salts  Sixty-five percent of bone by mass  Mainly calcium phosphates  Responsible for bone hardness and its resistance to compression Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 41.  Hydroxylapatite, also called hydroxyapatite (HA), is a naturally occurring mineral form of calcium apatite with the formula Ca5(PO4)3(OH), but is usually written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two entities. Hydroxylapatite is the hydroxyl endmember of the complex apatite group. The OH- ion can be replaced by fluoride, chloride or carbonate, producing fluorapatite or chlorapatite. fluorosis. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 42. Bone Development  Osteogenesis and ossification – the process of bone tissue formation, which leads to:  The formation of the bony skeleton in embryos  Bone growth until early adulthood  Bone thickness, remodeling, and repair Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 43. Formation of the Bony Skeleton  Begins at week 8 of embryo development  Intramembranous ossification – bone develops from a fibrous membrane  Endochondral ossification – bone forms by replacing hyaline cartilage Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
  • 44. Intramembranous Ossification  Formation of most of the flat bones of the skull and the clavicles  Fibrous connective tissue membranes are formed by mesenchymal cells Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings