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Emerging CT
technologies are racing
to meet the future of
noninvasive cardiology
S. Achenbach
Disclosure: Research Support,
Siemens Medical Solutions
CARDIAC IMAGING:
- Complex Anatomy
- Small Dimensions
- Rapid Movement
Z
Continuous x-ray data
acquisition and table feed
Simultaneous recording of
ECG signal
Multi-Detector Spiral/Helical CT
Z
Continuous x-ray data
acquisition and table feed
Simultaneous recording of
ECG signal
ECG-gated image
reonstruction
Multi-Detector Spiral/Helical CT
Z
Continuous x-ray data
acquisition and table feed
Simultaneous recording of
ECG signal
ECG-gated image
reonstruction
Partial scan reconstruction
Multi-Detector Spiral/Helical CT
16-slice MSCT:
370-500 ms rotation
16 x 0.5-0.75 mm collimation
~ 18 s breathhold, 80 - 100 ml of contrast
64-slice MSCT:
330-420 ms rotation
64 x 0.5-0.6 mm collimation
~ 6-12 s breathhold, 50-70 ml of contrast
16-slice MSCT:
370-500 ms rotation
16 x 0.5-0.75 mm collimation
~ 18 s breathhold, 80 - 100 ml of contrast
64-slice MSCT:
330-420 ms rotation
64 x 0.5-0.6 mm collimation
~ 6-12 s breathhold, 50-70 ml of contrast
Spatial resolution:
0.4 mm x 0.4 mm x 0.4 mm
Temporal resolution: ~165 ms
EBT (3mm) 4 slice (1.25mm) 16 slice (0.75mm) 64 slice (0.6mm)
1994 2000 2002
2004
EBT (3mm) 4 slice (1.25mm) 16 slice (0.75mm) 64 slice (0.6mm)
1994 2000 2002
2004
96-99% negative
predictive value for
detection of
coronary stenoses
Mollet et al, JACC 2005
Morgan-Hughes et al, Heart 2005
Kuettner et al, JACC 2005
Achenbach et al, Eur Heart J 2005
Hoffmann et al, JAMA 2005
Raff et al, JACC 2005
Leschke et al, Eur Heart J 2005
Leber et al, JACC 2005
Mollet et al, Circulation 2005
96-100% sensitivity
for bypass graft
occlusion
Nieman et al, Radiology 2003
Schlosser et al, JACC 2004,
Martuscelli et al, Circulation 2004
Chiurlia et al, AJC 2005
Limited spatial and
temporal resolution
as compared to
- cardiac cath
- size and speed of
coronary arteries
-
LIMITATIONS:
Motion artifacts -- heart rate -- temporal res.
Spatial resolution -- radiation
Several heart beats -- arrhythmias
FUTURE PATHS:
> 64 slices: shorter breathhold /
less contrast
>> 64 slices: one heart beat (120 mm)?
< 0.5 mm slices: spatial resolution – radiation!
Faster rotation: better temporal resolution
FUTURE PATHS:
Better temporal resolution
=> Prospective triggering
=> Less radiation
=> Thinner slices?
We will see:
Up to 256-slice scanners
Faster temporal resolution
Better software
Heart 2005
We will see:
Up to 256-slice scanners
Faster temporal resolution
Better software
We will see:
Up to 256-slice scanners
Faster temporal resolution
Better software Heart Phantom with Stent at 95bpm
Sensation 64, 165ms 83ms
SUMMARY
Temporal resolution and spatial resolution
as well as radiation/noise are issues in
cardiac CT
Simply adding more slices will not solve
the major problems
=> One heart beat (256 sl.)
=> Temporal resolution
=> COST?
2005
10 years
1995
2005
10 years 10 years
2015
?
1995
Education, carefully performed studies,
and good guidelines will be at least as
important as new technology..
www.SCCT.org
Society of Cardiovascular CT

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Emerging CT Technologies Racing to Meet Noninvasive Cardiology

  • 1. Emerging CT technologies are racing to meet the future of noninvasive cardiology S. Achenbach Disclosure: Research Support, Siemens Medical Solutions
  • 2. CARDIAC IMAGING: - Complex Anatomy - Small Dimensions - Rapid Movement
  • 3. Z Continuous x-ray data acquisition and table feed Simultaneous recording of ECG signal Multi-Detector Spiral/Helical CT
  • 4. Z Continuous x-ray data acquisition and table feed Simultaneous recording of ECG signal ECG-gated image reonstruction Multi-Detector Spiral/Helical CT
  • 5. Z Continuous x-ray data acquisition and table feed Simultaneous recording of ECG signal ECG-gated image reonstruction Partial scan reconstruction Multi-Detector Spiral/Helical CT
  • 6. 16-slice MSCT: 370-500 ms rotation 16 x 0.5-0.75 mm collimation ~ 18 s breathhold, 80 - 100 ml of contrast 64-slice MSCT: 330-420 ms rotation 64 x 0.5-0.6 mm collimation ~ 6-12 s breathhold, 50-70 ml of contrast
  • 7. 16-slice MSCT: 370-500 ms rotation 16 x 0.5-0.75 mm collimation ~ 18 s breathhold, 80 - 100 ml of contrast 64-slice MSCT: 330-420 ms rotation 64 x 0.5-0.6 mm collimation ~ 6-12 s breathhold, 50-70 ml of contrast Spatial resolution: 0.4 mm x 0.4 mm x 0.4 mm Temporal resolution: ~165 ms
  • 8. EBT (3mm) 4 slice (1.25mm) 16 slice (0.75mm) 64 slice (0.6mm) 1994 2000 2002 2004
  • 9. EBT (3mm) 4 slice (1.25mm) 16 slice (0.75mm) 64 slice (0.6mm) 1994 2000 2002 2004
  • 10. 96-99% negative predictive value for detection of coronary stenoses Mollet et al, JACC 2005 Morgan-Hughes et al, Heart 2005 Kuettner et al, JACC 2005 Achenbach et al, Eur Heart J 2005 Hoffmann et al, JAMA 2005 Raff et al, JACC 2005 Leschke et al, Eur Heart J 2005 Leber et al, JACC 2005 Mollet et al, Circulation 2005
  • 11. 96-100% sensitivity for bypass graft occlusion Nieman et al, Radiology 2003 Schlosser et al, JACC 2004, Martuscelli et al, Circulation 2004 Chiurlia et al, AJC 2005
  • 12.
  • 13. Limited spatial and temporal resolution as compared to - cardiac cath - size and speed of coronary arteries -
  • 14.
  • 15. LIMITATIONS: Motion artifacts -- heart rate -- temporal res. Spatial resolution -- radiation Several heart beats -- arrhythmias
  • 16. FUTURE PATHS: > 64 slices: shorter breathhold / less contrast >> 64 slices: one heart beat (120 mm)? < 0.5 mm slices: spatial resolution – radiation! Faster rotation: better temporal resolution
  • 17. FUTURE PATHS: Better temporal resolution => Prospective triggering => Less radiation => Thinner slices?
  • 18. We will see: Up to 256-slice scanners Faster temporal resolution Better software Heart 2005
  • 19. We will see: Up to 256-slice scanners Faster temporal resolution Better software
  • 20. We will see: Up to 256-slice scanners Faster temporal resolution Better software Heart Phantom with Stent at 95bpm Sensation 64, 165ms 83ms
  • 21. SUMMARY Temporal resolution and spatial resolution as well as radiation/noise are issues in cardiac CT Simply adding more slices will not solve the major problems => One heart beat (256 sl.) => Temporal resolution => COST?
  • 23. 2005 10 years 10 years 2015 ? 1995
  • 24. Education, carefully performed studies, and good guidelines will be at least as important as new technology..