Plenary lecture of the XVIII B-MRS Meeting given by Prof. Antonio José Roque da Silva (CNPEM, Brazil) on September 24, 2019 at Balneário Camboriú (Brazil).
ECG Graph Monitoring with AD8232 ECG Sensor & Arduino.pptx
Sirius: The New Brazilian Synchrotron Light Source.
1. Sirius: The New Brazilian Synchrotron Light Source
Antonio José Roque da Silva – jose.roque@cnpem.br
On behalf of the Sirius/CNPEM team
2. Outline
• Why synchrotrons
• How do they work
• LNLS and CNPEM
• Challenges and more brightness
• Sirius and fourth generation machines
• Status of Sirius
• Beamlines
• Conclusion
5. “New truths become
evident when new tools
become available”.
Rosalyn Sussman Yalow
1977 Nobel Prize in
Physiology and Medicine
Freeman Dyson
1997 Imagined Worlds
‘‘New directions in
science are launched
by new tools much
more often than by
new concepts”
Evolution of
instruments
Evolution of
knowledge
7. • Intense
• Broad spectrum
• Small and collimated source (coherent!)
Source area, S Source divergence, W
Brilliance=
Flux
(S x W)
Emittance
What makes a good light source?
8. Relativist case
Emission concentrated within a narrow forward cone
𝑣~𝑐
Electromagnetic Radiation by accelerated charges
Classical case
Centripetal acceleration
Isotropic emission
P. Willmot (Introduction to Synchrotron Radiation Science)
1
𝛾
= 1 − 𝑣2 𝑐2
𝑃 ∝
1
𝑚4
Electrons!
𝑣 ≪ 𝑐
9.
10.
11. First synchrotron light source in the southern
hemisphere
Around 85% built in house
Still the only one in Latin America
LNLS – A pioneering lab in Brazil
Training of human
resources
Built between 1987-1997
12. LNNano
LNLS
LNBR
LNBio
CNPEM is a private nonprofit organization working under contract with the
Brazilian Ministry of Science, Technology, Innovation and Communication
SIRIUS
UVX
14. GREAT CHALLENGES OF TODAY AND THE FUTURE
Important and challenging materials and systems are Inhomogeneous,
Hierarchic, Composites with distinct spatial and time scales
Petroleum reservoirs
Soil Brain
15. Most important/challenging materials and systems are Inhomogeneous,
Hierarchic, Composites with distinct spatial and time scales
Great Challenge!
We need "tools" that allow us to investigate any material, in
different spatial scales (from meso, to micro, to nano, to atomic),,
in different time scales, in real operating conditions, that will
generate 3D images, with different contrasts, such as:
– Concentration of chemical elements
– Chemical environment
– Oxidation state
– Chemical bonds
– Crystal structure
– Grain orientation
– Electronic density
– Magnetic moments
– …
19. WHERE THE WORLD IS MOVING
Jiajun Wang et al. (2016)
10 mm (50 nm resolution)
Jian et. al, PNAS (2010)
Cell Tomography
5D Tomography
Spatial resolution, temporal
evolution, chemical resolution
Charge-discharge process in Li ion
batteries
20. Need more brilliance!
10 μm (@ LNLS today)
High scanning Probe Resolution
Coherent Flux ~ Brilliancel2
High Coherence
e.g: lensless imaging with
nanometric resolution
e.g: Detection limits in chemical mapping
22. 2009-2012
- Prepared CDR and Scientific Case for a 3rd generation light source;
- Prototypes built; investment in infra-structure;
- MAC meeting (June 2012) → Go for a sub-nm.rad emittance
Sirius - a bit of history
2009-2012
- Prepared CDR and Scientific Case for a 3rd generation light source;
- Prototypes built; investment in infra-structure;
- MAC meeting (June 2012) → Go for a sub-nm.rad emittance
Sirius - a bit of history
23. Position depends on energy
N
S
N
S
N
S
E1
E2
How to decrease the emittance →increase number of dipoles
Split larger dipole into two smaller
ones is better for emittance reduction
But needs to refocus in the middle
Magnetic Lattice
24. • 3G in operation
𝜖0
𝛾2
∝ 𝐶−3
Natural emittance scaling (electrons in storage ring)
Area of the electron
phase space
𝜎𝑒 𝑥
𝜎𝑒 𝑥
’
Challenge is to place more dipoles and stronger quadrupoles and sextupoles without increasing the accelerator size
💲 😪
25. Diamond – 561.6 m (24 DBA)
𝜀 𝑒=2.7 nm.rad
528 m (20 7BA)
𝜀 𝑒=0.328 nm.rad
MAX IV Design – 7 Bend Achromat
26.
27. 27
Natural emittance of some Light Sources
4th Generation Storage Rings
Harry Westfahl
1996
2016
IPAC
29. 2009-2012
- Prepared CDR and Scientific Case for a 3rd generation light source;
- Prototypes built; investment in infra-structure;
- MAC meeting (June 2012) → Go for a sub-nm.rad emittance
New Sirius proposal four months after MAC meeting
- Since the end of 2012, complete redesign and development of all accelerator subsystems;
improvement of magnetic lattice; design and development of beamlines and components
Sirius - a bit of history
Emittance
0.25 nm.rad (bare)
0.15 nm.rad (IDs)
30. Dipoles
• Magnetic Material : NdFeB
• Maximum Field: 3.2 T
Sirius will have high magnetic field
permanent bending magnets
(Critical Energy ~ 20 keV)
34. Low b optics: phase-space matching
Numerical integration of Wigner Distribution Function
Gaussian approximation of reference [H. Westfahl Jr et al, JSR, 24, 2017]
e = 250 pm.rad
Courtesy: Harry Westfahl Jr
~Factor of 2
Low 𝜷 High 𝜷
Equivalent to increasing the
current by a factor of 2
36. 3.2 T BC 1.1 T 3PW
Brilliance and Coherent Flux Comparison
• Even with future upgrades, Sirius will
be the brightest in the energy range
of most important K-edges for:
– Medicine
– Agriculture
– Oil industry
– Petrochemical industry
ESRF-USirius
MAX IV
ALS-U
Sirius
ESRF-U
ALS-U
MAX IV
PS Cl KCa Ti Cr
• Even after the future upgrades of
3G synchrotrons Sirius will have
the largest coherent flux in the
tender x-ray. Optimal for
biological samples!
(3G synchrotrons ~ 108 ph/s)
Harry Westfahl
37. 2009-2012
- Prepared CDR and Scientific Case for a 3rd generation light source;
- Prototypes built; investment in infra-structure;
- MAC meeting (June 2012) → Go for a sub-nm.rad emittance
New Sirius proposal four months after MAC meeting
- Since the end of 2012, complete redesign and development of all accelerator subsystems;
improvement of magnetic lattice; design and development of beamlines and components
- End of 2012 until mid 2014 – Executive Project of building
- 2013 – Acquired land (State of São Paulo – 150.000 m2)
Sirius - a bit of history
38.
39. 2009-2012
- Prepared CDR and Scientific Case for a 3rd generation light source;
- Prototypes built; investment in infra-structure;
- MAC meeting (June 2012) → Go for a sub-nm.rad emittance
New Sirius proposal four months after MAC meeting
- Since the end of 2012, complete redesign and development of all accelerator subsystems;
improvement of magnetic lattice; design and development of beamlines and components
- End of 2012 until mid 2014 – Executive Project of building
- 2013 – Acquired land (State of São Paulo – 150.000 m2)
- December of 2014 – Signed contract with main building contractor (Racional Eng.)
- January 2015 – Building construction started
Sirius - a bit of history
40. SPECIAL FLOOR
Building
• Total area - 68.000 m2
• Special floor to minimize effects of vibration
on the accelerator and beamlines
49. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
* Mainly refurbished beamlines from the UVX machine
Sirius beamlines and science programs
*Based on Bending Magnets
50. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
*Based on Bending Magnets
Beam Spot ~200mm x 400mm ~5mm x 10mm
Flux ˜1010 ph/s ˜1013 ph/s
Time to struc. ˜hours ˜min
From UVX to Sirius
3D structure of challenging membrane proteins and
protein complexes
MANACA
(microfocus)
ESRF-ID231
Diamond- I24
(microfocus)
Wavelengths (Å) 0.61 – 3.0 0.61 – 2.47 0.7 – 2.0
Flux (ph/s) 1013 1012 3x 1012
Spot size (μm²) 10 x 5 to 80 x 80 10 x 10 to 45 x 30 5 x 5 to 50 x 40
Detector PIMEGA 540D Pilatus 6M Pilatus 6M
World class structural biology platform with LNBio
• Ligand-protein structure
• Membrane proteins
• Enzyme development
MANACÁ beamline
Ana Zeri
51. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
*Based on Bending Magnets
Pmax 80 GPa 800 GPa
Tmax 2000 K 8000 K
Tmin 5 K 0.3 K
Hmax 1 T ~10 T
Beam Spot 80 mm 1 mm
Flux ~109 ph/s ~1013 ph/s
From UVX to Sirius
Extreme conditions to the extreme!
World unique beamline to cover all these P,T,H conditions
• Quantum materials / new synthesis routes
• Geochemistry / geophysics in extreme environments
Narcizo Souza Neto
EMA beamline
52. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
*Based on Bending Magnets
FOV 8 mm 85 mm
Res. 1 mm 100 nm
Emax 14 keV 68 KeV
Flux (mono) ~109 ph/s ~1012 ph/s
From UVX to Sirius
Zoom tomography and in situ 4D tomography
First High Energy Cone Beam Tomography
beamline in the world!
• Rock tomography under pre-salt conditions
• In-vivo animal studies
• Porous structure of biomass and soil
Sirius - MOGNO ESRF-ID16A Petra II – P10
Energy (keV) 22 / 39 / 68 17 6-14
Flux
(ph/s/100mA)
1012/1011/2 1010 1012 1011
Source Size (nm2) 100x100 30x40 200x200
MOGNO beamline
Nathaly Archilia
53. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
*Based on Bending Magnets
Scatt. Flight Path 3 m 30 m
En. range 8 keV 3-15 KeV
Flux ~1011 ph/s ~1013 ph/s
(incoherent) (coherent)
From UVX to Sirius
X-Ray nano-tomography with plane wave CDI
and XPCS (“DLS with SAXS”)
First beamline to allow pw-CDI with 40mm FOV in seconds
• Eukaryotic Cell tomography
• In situ Nano tomography Nanostructured materials
Sirius -
CATERETE
ESRF-ID10 SLS- cSAXS
Energy (keV) 3-15 7-12 5-8
Coherent Flux
(ph/s/100mA)
1012 109 109
Focused FOV (mm2) 40x40 7x7 -
Florian Meneau
CATERETÊ beamline
54. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
*Based on Bending Magnets
Beam Spot ~20mm x 20mm ~30nm x 30nm
Flux ˜1010 ph/s ˜1012 ph/s
Time to map ˜hours ˜secs
From UVX to Sirius
Chemical mapping with nanometer resolution
First beamline to perform spectral imaging in the
tender x-rays (Ca, K, Cl, S, P) with nm resolution
• Chemical mapping of soil components
• Nano catalyst spectral imaging
Helio Tolentino
CARNAÚBA beamline
55. PHASE BEAMLINE ENERGY (keV) TECHNIQUES TECHNICAL
COMMISSIONING
I – A MANACÁ 5 – 20 Serial micro and nano MX August/2019
I – A EMA 3 – 35 Extreme Conditions November/2019
I – A MOGNO 20/40/70 Cone beam Tomography October/2019
I – A CATERETÊ 3 – 12 CDI, XPCS September/2019
I – A CARNAÚBA 2 – 15 spectro-ptychography December/2019
I – A IPÊ 0.08 – 2 AP-RIXS; ARPES December/2019
I – B SABIÁ 0.25 – 2.5 AP-XPS; XMCD 2021
I – B JATOBÁ 30 – 200 XRD-CT 2021
I – B INGÁ 4 – 24 IXS 2021
I – B QUATI 4 – 45 Quick-EXAFS 2021
I – B SAPUCAIA 4 – 24 High-Throughput SAXS 2021
I – B PAINEIRA 4 – 24 XPD 2021
II COLIBRI 0.1 – 1.5 PEEM, CDI 2020
II IMBÚIA 0.001 – 1 eV nano-FTIR 2020
II XARU 4 – 45 EXAFS 2020
II HARPIA 5 – 30 TR-XPD 2020
II HERA 30 – 120 XTMS 2020
II SAGUI 4 – 24 SAXS 2020
*Based on Bending Magnets
Beam Spot. ~1 mm ~1 mm
Ener. Res. ˜eV ˜10 meV
From UVX to Sirius
Soft X-ray spectroscopy with unprecedent resolution
ARPES and RIXS with world leading resolution
• Electrochemistry of surfaces and interfaces
• Quantum chemistry of enzymes and ligands
Mode
Beamline Flux
(ph/s/0.1A)
Spot size
(mm)
Flux density
(ph/s/mm2/0.1A)
High
Resolution
IPE 1.5 1011 1 x 3 5.5 1010
ADRESS (SLS) 5.0 1010 4 x 52 2.4 108
Tulio Rocha
IPÊ beamline
56. Beamlines
SOURCE (X-RAY
UNDULATOR)
MIRROR 1
SLIT
S
MONOCHROMATO
R
MIRROR
2
SAMPLE STAGEDETECTO
R
Cryo-cooled DCM
~10 nrad stability
~2-70 keV
Cryo-cooled x-ray mirrors
˜10 nrad deformation
~100 nrad stability
Sample Stages
- In situ cooling/heating
- Nano position / metrology
Beamline instrumentation highlights
Fast Area Detector
- Up to 9.6 Mpixel
- 24 bit
- 1000 FPS
58. Synchrotron Research Project pipeline
Sample
Synthesis/
preparation
Sample
preparation
Data
Acquisition
Data
Analysis
Modelling
Scientific
Documentation
Scientific
Proposal
Pre-characterization
At the synchrotron facilityToday:
Sample
Synthesis/
preparation
Sample
preparation
Data
Acquisition
Data
Analysis
Modelling
Scientific
Documentation
Scientific
Proposal
Pre-characterization
At the synchrotron facilityOn Sirius:
59. ~ 85% expenditures in Brazil
Brazilian Suppliers
Continuous interaction with many Brazilian companies in order to
find developers as well as suppliers for production
61. Neuron structure: Fonseca et al. , Sci. Rep. (2018)
X-Ray mCT (@ ~1 mm )
Nano FTIR (@~100 nm)
Composition: Oxana K. et al. (unpublished)
Nano X-Ray Fluorescence (@~10 nm)
Nanotomography:Deng et al. (Sci adv. 2019)
Small Angle X-Ray Scattering
And UV Circular Dichroism
(@~1 nm)
Vesicles: Castroph S. (Göttingen Series 2012)
α1
α2
α3
α4
N
C
310
β1
β2 β3
β4
Protein Crystallography (@~0.1 nm)
Proteins: De Oliveira, J. et al. (Nature Chem Bio 2019)
Normal
Alterada
C
88
Multiscale and multi-contrast imaging
62. Combining fluorescence and diffraction imaging
18 nm chemical resolution
State of the art!
• On current 3rd generation synchrotrons this image takes
~ 1 hour (Full 3D a couple of days!)
• On Sirius, with 1.000 – 10.000 more coherent flux
~ 1 s
• A 10.000 faster!Junjing Deng et al (2017) done @ APS
63. Conclusion
• Synchrotron Science in Brazil (Latin America) has been built from
ground up and reached a mature level to jump into a more
competitive scenario
• Sirius is planned to be one of the best machines in the world
• The science done by the users will determine its success
“New truths become evident when
new tools become available”.
Rosalyn Sussman Yalow
1977 Nobel Prize in Physiology and Medicine
65. Low b optics: Beam Stay-Clear
Delta Undulator Prototype
Delta polarizing undulator in Sirius
https://www6.slac.stanford.edu/news/2016-06-15-spiraling-
light-slac-x-ray-laser-offers-new-glimpses-molecules.aspx
Animation from the SLAC website:
Credit: Flavio Rodrigues & James Citadini
Full Polarization Control in X-rays
With: