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SOLUBILITY – 3
SOLVATION & ASSOCIATION
Presented By:
Mr. S.M. Ambore
Asst. Professor,
DK Patil Institute of Pharmacy, Loha. Nanded
LEARNING OUTCOMES….
Solvation
Association
Factors affecting Solvation
& Association
Factors affecting Solubility 2
3
1. It is Solute- Solvent interaction.
2. Due to Solvation solute gets stabilized in solution.
3. When water is used as a solvent for solvation, then process
is called as HYDRATION.
4. Unit of solvation is mol / sec.
SOLVATION
SOLVATION FOR IONS
4
5
SOLVATION FOR IONS
6
DKPatilInstituteofPharmacy
SOLVATION FOR MOLECULES
7
DKPatilInstituteofPharmacy
FACTORS AFFECTING SOLVATION
Factors
Affecting
Solvation
Surface area
(α)
Agitation/
stirring (α)
Temperature
(depends)
 It is the phenomena in which oppositely charged ions
comes together in a solution and forms a different
chemical entity.
 It is joining or addition of ions.
 It is well explained by Coulomb's Law.
8
DKPatilInstituteofPharmacy
ASSOCIATION
9
DKPatilInstituteofPharmacy
TYPES OF ION PAIR
A < B < C
10
Factors
Affecting
Association
Magnitude
of Electric
Charge
Dielectric
Constant
Distance
between
Charges
FACTORS AFFECTING ASSOCIATION
REFLECTION SPOT
Can you guess what will be the factors affecting
Solubility?
11
12
Nature of
Solute/Solvent
Surface area
Temperature
Pressure
pH
FACTORS AFFECTING SOLUBILITY
13

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Solubility 3: Solvation & Association