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polymer in pharmacy and application of polymers

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polymer in pharmacy and application of polymers

  1. 1. SEMINAR ON POLYMER IN PHARMACEUTICS R.C.PATEL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH SHIRPUR. 1 Presented by: Roshan G Bodhe M. Pharm I sem Roll no : 2 Department of pharmaceutics
  2. 2. CONTENT 2 1)Introduction 2)Classification of polymer 3)Properties of polymer 4)Characteristics of ideal polymer 5)Advantages of polymer 6)Application of polymer 7)References
  3. 3. INTRODUCTION 3     Polymer is coined from to Greek word “poly” means many “mer” means parts. Defination: polymer is defined as very large molecules having high molecular mass which are formed by joining of repeating structural unit on large scale. Monomer : repeating structural unit derived from some simple and reactive moleculeles are linked to each other by covalent bond. Polymerization : process of polymer formation.
  4. 4. 4
  5. 5. 5 Protein, cellulose, resin, rubber, alginate, gelatin, albumin. Nylon , teflon Polysterylin Polyethylene, polypropylene, PLA, PGA, Polyhydroxybutyrate , Polyanhydride, Polyacrylamide. Based on Sources
  6. 6. 6 Based on polymerization
  7. 7. 7 Based on Degradability
  8. 8. 8 Based on Nature
  9. 9. 9 Based on properties.
  10. 10. 10 Based on structure
  11. 11. 11      Should be inert and compatible with environment Should be non toxic Should be easily administered Should have good mechanical strength Should be biodegradable and biocompatible Characteristics of ideal polymer
  12. 12. 12 Advantages of polymer       Localised delivery of drug Sustained delivery of drug Decrease in dosing frequency Reduce side effect Improve patient compliance Biodegradable and biocompatible Disadvantages of polymer    Exhibit dose dumping effect High initial drug release after administration Low mechanical properties
  13. 13. 13 Applications
  14. 14. 14 POLYMER APPLICATION Polyethylene oxide Cosmetic pharmaceuticals Polyethylene glycol Swelling agent PVP Tablet granulation Polyvinyl alcohol Tablet binder and coating Ethyl cellulose Sustained release system Carboxy methyl cellulose Super disintegrant HPMC Coating and binder
  15. 15. 15 Application in Drug delivery system    In modified drug release delivery system Controlled release formulation Sustained release formulation Biomedical applications     Tissue engineering Bone fixation devices Vaascular graft Surgical adhesive
  16. 16.    Industrial Application Agriculture Application Packaging Application
  17. 17. REFERENCES 17 1.George odian Fourth Edition , Principlesof polymerization John willy & son ,INC Publication ,page no 60-65. 2. S.P. Vyas & R.K.Khar Targated & Controlled Drug Delivery System ,CBS Publication , Page Number 3.22
  18. 18. 18 3. Ganesh R. Godge & Nilima A. Chaudhari Advanced Drug delivery system Tech-max Publication Page No. 2.1-2.57 4. Bio degredable polymers & its application , International journal of bio-science & Bioinformatics Vol. no 3 sept 2011 page no 1-4 REFERENCES
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