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Global Cell/Tissue Culture Supplies Industry
Published on October 2010

                                                                                                              Report Summary

This report analyzes the worldwide markets for Cell/Tissue Culture Supplies in US$ Million by the following Product Segments: Media,
Sera, and Reagents. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and
Latin America. Annual estimates and forecasts are provided for the period 2007 through 2015. A seven-year historic analysis is also
provided for these markets.The report profiles 131 companies including many key and niche players such as Affymetrix, Inc.,
AMRESCO, Inc., BD Biosciences, Cell Culture Technologies, LLC, Cell Essentials, Inc., Irvine Scientific, Life Technologies
Corporation, Lonza Biologics Plc, Mediatech, Inc., Millipore Corporation, Medi-Cult A/S, MP Biomedicals, PerBio Science AB,
PromoCell GmbH, Sera Laboratories International, Sigma-Aldrich Corporation, SAFC Biosciences, and Vitrolife AB. Market data and
analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported
select online sources.




                                                                                                               Table of Content


CELL/TISSUE CULTURE SUPPLIES MCP-3538
A GLOBAL STRATEGIC BUSINESS REPORT



                                         CONTENTS



 1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS                                            1
     Study Reliability and Reporting Limitations                             1
     Disclaimers                                             2
     Data Interpretation & Reporting Level                               2
      Quantitative Techniques & Analytics                                3
     Product Definitions and Scope of Study                                  3
      Cell/Tissue Culture Media, Sera and Reagents                               3


 2. MARKET DYNAMICS                                                      5
     Outlook                                             5
     Biopharmaceutical Drugs Fuel Cell Culture Market                            5
     Market Scenario                                             6
      Industrial vs. Academic                                        6
      Biotechnology Sector - Affected by Collapse of Capital Market                  6
     Global Market Analysis                                          6
     Market Structure                                            7


 3. TRENDS AND ISSUES                                                    8



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     US Government's Policies to Boost Cell Culture Market                             8
     Surging Demand for Cell Culture Products                                 8
     Stem Cells and Vaccines - Key Drivers                                8
     Growing Acceptance for Hi-Veg Culture Media                                  8
     Fed-Batch Cultures - a Big Hit with Large-Scale Bioprocessors                         9
     Changing Trend Towards Serum-Free Media                                       9
     Proteomics and Pharmacokinetics to Drive Market Growth                                9
      Bioresearch and Cell Culture in Protein-Based Drug Development                           10
     CHO, Hybridomas and Mabs Dominate Mammalian Cell Culture                                    11
     Sluggish Fetal Bovine Serum Market                                   11
     Specialty Media Demand on Rise                                       11
     Emerging Alternatives to Conventional Serum Supplemented Media                              12
     Growth of Defined Media                                       12
     Regulations Prompt Change in Trends                                     12
     Media Optimization                                       12
     Cell-Line Engineering Vs. Cell Culture Media                             12
     Other Trends                                        13
      Underlying Threat to Cell Culture Industry                          13
      Manufacture-on-Demand: Gaining Momentum                                          13
      Move Towards Contract Manufacturing                                     13
       Factors Impacting Growth                                    14
       Business Models Driving the Need for Contract Manufacturing                          14
       Trends in Contract Manufacturing                                 14
       Target Sectors for Contract Manufacturers                             14


 4. END-USE ANALYSIS                                                 16
     End-Use Applications                                       16
     Cell Therapy                                        16
      Growing by Leaps and Bounds                                       16
      Cell Therapy Applications                                 17
      Key Factors Affecting the Cell Therapy Market                            17
      Future Trends                                      17
     Related Market Sectors                                     17
      Progenitor Cell Therapy                                   17
      Stem Cell Therapy                                       18
      Other Related Technologies                                     19
       Somatic Cell Nuclear Transfer (SCNT)                               19
     Tissue Engineering                                       19
      End Use Industries                                      19


 5. CELL/TISSUE CULTURE: PHYSIOLOGICAL OVERVIEW                                                       20
     Introduction                                     20
     History                                        20
     Plant Cell and Tissue Culture (PCTC)                                 24
     Cell/Tissue Culture Media, Sera and Reagents                                 27
      Classical Media                                      27
      Specialty Media                                      28
      Serum                                           28
      Fetal Bovine Serum                                      28
      Serum-Free Media                                        28


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      Cell Culture Reagents                                    29
     Role of Tissue Culture in the Growth of Cell Types                         29
      Equipment                                           29
      Storage and Preservation                                      29
      Maintenance                                         30
       Growth Pattern                                      30
       Harvesting                                     30
       Media and Growth Requirements                                      31
        Physiological Parameters                                    31
        Medium Requirements (Often Empirical)                                 31
        Feeding                                       31
      Safety Precautions                                       31
     Methods of Tissue Culture                                      32
      Preparation of Media                                     32
      Growth and Morphology                                         32
      Sub Culturing Adherent Cells                                  32
      Thawing Frozen Cells                                      32
      Freezing Cells                                      32
     Cell Culture Contamination - A Looming Problem                                 33
      Classification                                  33
      Major Cell Culture Contaminants                                    33
       Chemical Contamination                                       33
        Types and Sources of Potential Chemical Contaminants                             33
        Varied Sources of Chemical Contamination                               34
        Media and Components                                        34
        Sera                                         34
        Water                                        35
        Storage Vessels                                    35
        Fluorescent Lights                                 35
        Endotoxins                                        35
        Incubators                                    36
       Biological Contamination                                 36
        Varied Sources of Biological Contamination                             37
        Mycoplasmas                                        37
        Airborne Particles and Aerosols                              37
       Cross Contamination by Other Cell Cultures                              38
      Consequences/Problems of Contamination                                    38
      Controlling Cell Culture Contamination                              38
       Measures Aimed at Reducing Contamination Problems                                  39


 6. REGULATORY ENVIRONMENT                                                          40


 7. PRODUCT INNOVATIONS/INTRODUCTIONS                                                         41
     StemCells Introduces GS1-R'                                     41
     Kollodis BioSciences Introduces Cell-Culture Reagents                           41
     The Automation Partnership Launches Automated Cell-Culture                               41
     Novartis Receives Approval to Release its New Vaccine                               42
     Invitrogen Introduces GIBCO® OpTmizer TM T-cell Expansion SFM                                 42
     Novozymes Biopharma Rolls Out CellPrime in Partner ship with
      Millipore                                      42


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     Invitrogen Launches Dynabeads® SSEA-4                                 43
     Invitrogen Rolls Out KNOCKOUTTM SR XenoFree Media                                    43
     Lonza Develops One-Step Program                                  43
     Millipore Unveils ESGRO CompleteTM PLUS Medium                                   43
     Millipore Introduces Hanging Millicell® Cell Culture Inserts              43
     SAFC Biosciences® Launches EX-CELLTM EBx®                                       44
     SAFC Biosciences® Rolls Out EX-Fusion and CHO Library                               44
     Millipore Launches Epidermal Keratinocyte 3D Medium                            44
     Invitrogen Rolls Out PD-Direct® Bioprocess Services                       45
     Millipore Unveils a New Variety of Primary Human Epithelial Cells               45
     BD Biosciences Introduces BD Analysis Kit                            46
     Thermo Fisher Scientific Rolls Out Thermo Clone                       46
     Lonza Introduces Poietics® Human Natural Killer (NK) Cells                     46
     Millipore Launches New MillicoatTM Cultureware                            47
     Millipore Unveils High Content Analysis Kits                     47
     Millipore Rolls Out FlowCellect'                           47
     Invitrogen Introduces GIBCO® Bottles                             47
     Invitrogen Unveils ST SFM, STEO and STEA Differentiation Kits                       48
     Thermo Fisher Scientific Launches NuncTM UpCellTM Surface                            48
     Millipore Releases New Primary Human Epithelial Cell Cultures                   48
     Millipore Expands Stem Cell Tested Initiative                    49
     BD Biosciences Debuts BD FACSAria' II System to Sort Cells                       49
     Invitrogen Introduces Specific SFM for the Mesenchymal Stem Cells                    49
     StemCell Launches Cryopreservation Medium Free from Serum                             50
     Invitrogen Unveils SequalPrep' System                            50
     Invitrogen Introduces Animal Source-Free Substrate                        50
     Invitrogen Introduces GIBCO® FoamAway' Reagent                                 50
     Genetix Develops New CytoGenetix Reagents and Kits                              51


 8. PRODUCT INTRODUCTIONS/INNOVATIONS IN THE RECENT PAST -
     A PERSPECTIVE BUILDER                                            52
     Thermo Fisher Launches NUNC In Vitro PDL Coated PETG Roller
      Bottles                                        52
     Thermo Fisher Scientific Introduces HyClone AdvanceSTEM' Cell
      Culture Product Line                                 52
     Thermo Fisher Scientific Introduces New Medium to Culture PER
      .C6 Cell Line                                   52
     Genetix Expands CloneMedia Semi-Solid Media Products                             52
     Invitrogen Launches STEMPRO® EZPassage' Tool                                    53
     Sigma-Aldrich Introduces GenomePlex Tissue WGA Kit                              53
     Thermo Fisher Scientific Introduces Two New Versatile Media
      for HEK 293 Cell Line                                53
     SAFC Biosciences Launches LONG®R3IGF-I in Liquid Form                                53
     Invitrogen and Novocell Introduce Media for hESC Growth                        54
     Invitrogen Releases New Culture System                               54
     Invitrogen Introduces New Line of Engineered Stem Cells                        54
     BD Biosciences Partners with StemCell Technologies                         54
     Millipore Launches MEL Cell Lines                               55
     Irvine Scientific Expands Industrial Cell Culture Product Line             55
     Biovest International Introduces Automated Cell Culture Device                  55


Global Cell/Tissue Culture Supplies Industry                                                                                Page 4/17
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     BD Biosciences Introduces BD FACSDiva' 6.0 Software                             56
     Millipore Unveils Nylon Net Steriflip® Filter Unit                56
     Lonza Expands Product-Portfolio with Serum Free Media                           56
     MediCult Unveils Flexible Culture Systems, BlastAssist® and
      EmbryoAssist'                                        56
     Millipore Introduces New Medium for Human Embryonic Stem Cell
      Research                                            57
     Invitrogen Launches CytoGenie' Cytometry Software Tool                          57
     Novozymes Releases New Cell Culture Components                                  57
     The Automation Partnership Launches Advanced Plating Module                           57
     Nikon Unveils BioStation CT                                 58
     Corning Launches Innovative Cell Culture Solutions                         58
     GroPep Introduces New Assay Kit for Cell Culture Business                       58
     HyClone Introduces HyQ®CDM4MAb' for Hybridoma Cell Lines                              58
     INTEGRA Biosciences Adds Alarm Interface to CELLROLL and
      CELLSPIN Systems                                          59
     Nikon Launches New Imaging and Tracking Systems for Cell Culture                      59
     Genetix Develops Cell Dispenser                                 59
     SAFC Biosciences Introduces LONGTMR3IGF-I for Industrial Cell
      Culture                                         59
     Biocrystal Presents Opticell                               59
     TAP Unveils CompacT SelecT'                                      60
     New Brunswick Scientific Augments New Products to Cell Culture
      Systems                                             60
     Cell Culture Technologies Develops Fortified Production Media                   60


 9. RECENT INDUSTRY ACTIVITY                                               61
     Akron Biotechnology Merges with AppliChem                              61
     ChanTest Takes Over Applied Cell Sciences                              61
     Millipore to Takeover Guava Technologies                              61
     Millipore Acquires EpiTagTM Technology from Epitome Biosystems                        62
     MediCult's BlastAssist® Culture Media Obtains FDA Approval                       62
     Capsant Signs Commercialization Agreement with VistaGen                          62
     Millipore Inks Distribution Agreement with Solabia                    63
     Helix BioMedix Signs Production and Supply Agreement with
      Peptisyntha                                         63
     BD Biosciences to Establish New Production Facility                        63
     Lonza Group Takes Over amaxa                                     64
     Millipore and Bayer Healthcare Sign Agreement                          64
     Applied Biosystems and Invitrogen Merge                               64
     SAFC BiosciencesTM and Celltrion Enter into Agreement                           64
     Tata Chemicals to Acquire Stake in Joil                          65
     Sartorius Stedim Biotech Acquires Wave Biotech                             65
     Sigma-Aldrich and AlphaGenix Sign Distribution Agreement                        65
     Induce Biologics and Therapure Biopharma Enter into Collaboration                    65
     International Stem Cell and Millipore Sign Distribution Agreement               65
     Lonza Signs Agreement with Crucell                               66
     Eden Biodesign and Human Genome Sciences Sign Agreement                                   66
     Becton, Dickinson to Establish New Production Facility                     66
     MedCell Bioscience Merges with NovaThera                               66


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     Covidien UK Holding Takes Over Tissue Science Laboratories                     67
     Invitrogen Establishes Dedicated Business Unit for Cell Therapy               67
     Invitrogen Signs Deal to Acquire CellzDirect                   67
     Invitrogen Renews Agreement with Luminex Corporation                       67
     BioTime Establishes Tissue Culture Facility                    68
     International Stem Cell Signs Agreement with ATCC                        68
     Millipore Signs Agreement with Solabia to Distribute Animal-
      Free Hydrolysates                                   68
     Affymetrix Acquires USB Corporation                            69
     SAFC to Expand Production Capacity of Viral Product                      69
     Lonza Signs Partnership Agreement with Sanofi to Produce Cell
      Culture Vaccine                                  69


 10. STRATEGIC CORPORATE ACTIVITY IN THE RECENT PAST -
     A PERSPECTIVE BUILDER                                          70
     SAFC to Increase Fermentation Capabilities of High-Potency API                 70
     Biogen Offers Contract to Jacobs Engineering Group                       70
     New Brunswick Scientific Merges with Eppendorf Group                      70
     Vitrolife Extends Agreement with Cellartis                     70
     Sigma-Aldrich Inks Distribution Agreement with CellPath                  70
     Lonza Acquires two Subsidiaries of Cambrex Bio-Businesses                     71
     Vikdas to Build Biotechnological Laboratory                     71
     Novartis to Invest in a New Cell Culture Plant in Singapore          71
     Invitrogen Signs Agreement with Biocon                         71
     Lonza and Bio*One form Joint Venture for Mammalian Cell
      Culture Plant                                  71
     Thermo Fisher to Extend Manufacturing Operations                      72
     BD Biosciences Announces Treyburn Expansion Plans                             72
     BD Biosciences Collaborates with Roche to Advance Cell Signal
      Transduction Study                                  72
     Invitrogen and RXi Pharmaceuticals Enter into Collaboration               73
     Millipore Forms a Strategic Alliance with Novozymes                  73
     Thermo Fisher Takes Over OptiCell Product Line                       73
     Invitrogen Collaborates with Cytori for Research on Adipose
      Stem Cell                                     73
     Thermo Fisher Partners with Cellular Engineering for Stem Cell
      Research                                       74
     VWR Signs Agreement to Distribute Biovest's Cell Culture Device                74
     Genentech Constructs New Cell Culture Plant                         74
     Invitrogen Signs Deal with Wave Biotech to Offer Media-Filled
      Disposable Bioreactors                                74
     MediCult Purchases Humagen Fertility                           74
     Millipore Acquires Serologicals                           75
     ReNeuron Inks Collaboration Agreement with CellSeed                       75
     Trans Valley Launches Tissue Cultured Variety of Mushrooms                     75
     HiMedia Laboratories Forges Distribution Deal with VWR
      International                                  75
     Teva Signs Collaboration Agreement with Protalix Biotherapeutics               75
     SAFC-Biosciences Forms to Support Sigma-Aldrich                          76
     Invitrogen and Cellartis to Co-develop hESC Reporter Lines                76


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     CELLCA and Rentschler Join Forces for Unique High-Level
      Expression System                                      76
     ArcDia Partners with Chip-Man Technologies                              76
     Chugai Pharmaceutical Receives License for Cell Line from
      Cambrex Bio Science Walkersville, Inc.                            76
     Chemicon Inks Distribution Agreement with CELLnTEC                                77
     Chemicon Signs an Agreement with ReNeuron                                    77
     Chemicon to Market Stem Cell Products of ASCC                                77
     SCS and Chemicon Introduce ESGRO Complete' Product Range                                 77
     Serologicals Acquires Cytomyx Ltd                                 78
     Millipore to Take Over Serologicals                           78
     CAT Opts SelectT' for Higher Cell Culture Yields                        78


 11. FOCUS ON SELECT MAJOR PLAYERS                                                     79
     Affymetrix, Inc. (USA)                              79
     AMRESCO, Inc. (USA)                                          79
     BD Biosciences (USA)                                     79
     Cell Culture Technologies, LLC (Switzerland)                           80
     Cell Essentials, Inc. (USA)                             80
     Irvine Scientific (USA)                             80
     Life Technologies Corporation (USA)                               80
     Lonza Biologics Plc (UK)                                 81
     Mediatech, Inc. (USA)                                   81
     Millipore Corporation (USA)                              81
     Medi-Cult A/S (Denmark)                                  81
     MP Biomedicals (USA)                                     82
     PerBio Science AB (Sweden)                                    82
     PromoCell GmbH (Germany)                                          82
     Sera Laboratories International (UK)                          82
     Sigma-Aldrich Corporation (USA)                                   83
      SAFC Biosciences (USA)                                      83
     Vitrolife AB (Sweden)                                   83


 12. GLOBAL MARKET PERSPECTIVE                                                    84
     Table 1: World Recent Past, Current & Future Analysis for
     Cell/Tissue Culture Supplies by Geographic Region - USA,
     Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
     Latin American Markets Independently Analyzed with Annual
     Sales Figures in US$ Million for Years 2007 through 2015
     (includes corresponding Graph/Chart)                               84


     Table 2: World Historic Review for Cell/Tissue Culture
     Supplies by Geographic Region - USA, Canada, Japan, Europe,
     Asia-Pacific (excluding Japan) and Latin American Markets
     Independently Analyzed with Annual Sales Figures in US$
     Million for Years 2000 through 2006 (includes corresponding
     Graph/Chart)                                       85


     Table 3: World 11-Year Perspective for Cell/Tissue Culture
     Supplies by Geographic Region - Percentage Breakdown of Dollar


Global Cell/Tissue Culture Supplies Industry                                                                                  Page 7/17
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     Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding
     Japan) & Latin America Markets for Years 2005, 2010 & 2015
     (includes corresponding Graph/Chart)                        86
     Cell/Tissue Culture Supplies Market by Product Segment              87
     Table 4: World Recent Past, Current & Future Analysis for
     Media Cell/Tissue Culture Supplies by Geographic Region - USA,
     Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
     Latin American Markets Independently Analyzed with Annual
     Sales Figures in US$ Million for Years 2007 through 2015
     (includes corresponding Graph/Chart)                        87


     Table 5: World Historic Review for Media Cell/Tissue Culture
     Supplies by Geographic Region - USA, Canada, Japan, Europe,
     Asia-Pacific (excluding Japan) and Latin American Markets
     Independently Analyzed with Annual Sales Figures in US$
     Million for Years 2000 through 2006 (includes corresponding
     Graph/Chart)                                    88


     Table 6: World 11-Year Perspective for Media Cell/Tissue
     Culture Supplies by Geographic Region - Percentage Breakdown
     of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific
     (excluding Japan) & Latin America Markets for Years 2005, 2010 &
     2015 (includes corresponding Graph/Chart)                      89


     Table 7: World Recent Past, Current & Future Analysis for Sera
     Cell/Tissue Culture Supplies by Geographic Region - USA,
     Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
     Latin American Markets Independently Analyzed with Annual
     Sales Figures in US$ Million for Years 2007 through 2015
     (includes corresponding Graph/Chart)                        90


     Table 8: World Historic Review for Sera Cell/Tissue Culture
     Supplies by Geographic Region - USA, Canada, Japan, Europe,
     Asia-Pacific (excluding Japan) and Latin American Markets
     Independently Analyzed with Annual Sales Figures in US$
     Million for Years 2000 through 2006 (includes corresponding
     Graph/Chart)                                    91


     Table 9: World 11-Year Perspective for Sera Cell/Tissue
     Culture Supplies by Geographic Region - Percentage Breakdown
     of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific
     (excluding Japan) & Latin America Markets for Years2005, 2010 &
     2015 (includes corresponding Graph/Chart)                      92


     Table 10: World Recent Past, Current & Future Analysis for
     Reagent Cell/Tissue Culture Supplies by Geographic Region -
     USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and
     Latin American Markets Independently Analyzed with Annual
     Sales Figures in US$ Million for Years 2007 through 2015
     (includes corresponding Graph/Chart)                        93


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     Table 11: World Historic Review for Reagent Cell/Tissue
     Culture Supplies by Geographic Region - USA, Canada, Japan,
     Europe, Asia-Pacific (excluding Japan) and Latin American
     Markets Independently Analyzed with Annual Sales Figures in
     US$ Million for Years 2000 through 2006 (includes
     corresponding Graph/Chart)                                 94


     Table 12: World 11-Year Perspective for Reagent Cell/ Tissue
     Culture Supplies by Geographic Region - Percentage Breakdown
     of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific
     (excluding Japan) & Latin America Markets for Years2005, 2010 &
     2015 (includes corresponding Graph/Chart)                            95


 13. THE UNITED STATES                                              96
     A.Market Analysis                                    96
       Current & Future Analysis                               96
       Cell & Tissue Culture Market                            96
        A Brief Insight                              96
       Market Trends                                     97
        Trend Towards Serum-Free Media                                97
        Liquid and Powdered Media Account for Major Share                       97
         Table 13: Leading Players in the US Cell Culture Media
         Market (2008): Percentage Breakdown of Sales for -
         Sigma-Aldrich, Hyclone, Lonza Biologics, and Others
         (includes corresponding Graph/Chart)                        97
        Fetal Bovine Serum - On A Decline                            98
        Rise in Cell Culture Equipment Demand Leads to Innovation                98
        Market for Stem Cell Research                           98
       End-Use Analysis                                   99
        Table 14: US Market for Cell Culture Reagents by End Use -
        Academic, Industrial, and Non-Academic (2008) (includes
        corresponding Graph/Chart)                              99
       Factors Influencing the Market for Tissue and Cell Culture
        Media                                       99
       Regulatory Controls                                99
       Guidelines Governing Use of Cell/Tissue Culture Reagents                  100
        MSDS and Hazardous Information                               100
        Toxic Substances Control Act                            100
     B.Market Analytics                                   101
       Table 15: US Recent Past, Current & Future Analysis for
       Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                          101


       Table 16: US Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes


Global Cell/Tissue Culture Supplies Industry                                                                           Page 9/17
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       corresponding Graph/Chart)                            102


       Table 17: US 11-Year Perspective for Cell/Tissue Culture
       Supplies by Product Segment - Percentage Breakdown of Dollar
       Sales for Media, Sera, and Reagents Markets for Years 2005,
       2010 & 2015 (includes corresponding Graph/Chart)               103


 14. CANADA                                            104
     A.Market Analysis                                 104
       Current & Future Analysis                           104
       Biotechnology Industry                              104
     B.Market Analytics                                105
       Table 18: Canadian Recent Past, Current & Future Analysis
       for Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                    105


       Table 19: Canadian Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                            106


       Table 20: Canadian 11-Year Perspective for Cell/Tissue
       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera, and Reagents Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)         106


 15. JAPAN                                           107
     A.Market Analysis                                 107
       Current & Future Analysis                           107
     B.Market Analytics                                107
       Table 21: Japanese Recent Past, Current & Future Analysis
       for Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                    107


       Table 22: Japanese Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                            108


       Table 23: Japanese 11-Year Perspective for Cell/Tissue
       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera, and Reagents Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)         108




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 16. EUROPE                                             109
     A.Market Analysis                                  109
       Current & Future Analysis                            109
       Market Overview                                  109
     B.Market Analytics                                 110
       Table 24: European Recent Past, Current & Future Analysis
       for Cell/Tissue Culture Supplies by Geographic Region -
       France, Germany, UK, Italy & Rest of Europe Markets
       Independently Analyzed with Annual Sales Figures in US$
       Million for Years 2007 through 2015 (includes corresponding
       Graph/Chart)                                   110


       Table 25: European Historic Review for Cell/Tissue Culture
       Supplies by Geographic Region - France, Germany, UK, Italy
       and Rest of Europe Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2000 through
       2006 (includes corresponding Graph/Chart)                    111


       Table 26: European Recent Past, Current & Future Analysis
       for Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                    112


       Table 27: European Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                             113


       Table 28: European 11-Year Perspective for Cell/Tissue
       Culture Supplies by Geographic Region - Percentage Breakdown
       of Dollar Sales for France, Germany, UK, Italy & Rest of
       Europe Markets for Years2005, 2010 & 2015 (includes
       corresponding Graph/Chart)                             114


       Table 29: European 11-Year Perspective for Cell/Tissue
       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera, and Reagents Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)       115


 16a. FRANCE                                            116
      Market Analysis                                  116
       Current & Future Analysis                            116
       Table 30: French Recent Past, Current & Future Analysis for
       Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                    116




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       Table 31: French Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                               117


       Table 32: French 11-Year Perspective for Cell/Tissue Culture
       Supplies by Product Segment - Percentage Breakdown of Dollar
       Sales for Media, Sera, and Reagents Markets for Years 2005,
       2010 & 2015 (includes corresponding Graph/Chart)                 117


 16b. GERMANY                                                118
     A.Market Analysis                                    118
       Current & Future Analysis                             118
       Biotech Research Scenario                                118
        Table 33: German Biotech Market (2009): Percentage
        Breakdown by Application Area - Environment, Human Health
        Care, Chemical industry, Food, Agriculture, Energy, and
        Others (includes corresponding Graph/Chart)                   119
     B.Market Analytics                                   119
       Table 34: German Recent Past, Current & Future Analysis for
       Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                      119


       Table 35: German Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                               120


       Table 36: German 11-Year Perspective for Cell/Tissue Culture
       Supplies by Product Segment - Percentage Breakdown of Dollar
       Sales for Media, Sera, and Reagents Markets for Years2005,
       2010 & 2015 (includes corresponding Graph/Chart)                 120


 16c. ITALY                                            121
      Market Analysis                                    121
       Current & Future Analysis                             121
       Table 37: Italian Recent Past, Current & Future Analysis for
       Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                      121


       Table 38: Italian Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2000 through 2006 (includes


Global Cell/Tissue Culture Supplies Industry                                                                    Page 12/17
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ReportLinker                                                                            and Market Statistics


       corresponding Graph/Chart)                               122


       Table 39: Italian 11-Year Perspective for Cell/Tissue
       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera, and Reagents Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)              122


 16d. THE UNITED KINGDOM                                             123
     A.Market Analysis                                   123
       Current & Future Analysis                               123
       Biotechnology Industry - A Brief Insight                  123
       Regulatory Issues                                 124
        HFE Act Guidelines                                 124
        The Ethical Issues                              124
     B.Market Analytics                                  125
       Table 40: UK Recent Past, Current & Future Analysis for
       Cell/Tissue Culture Supplies by Product Segment - Media,
       Sera, and Reagents Markets Independently Analyzed with
       Annual Sales Figures in US$ Million for Years 2007 through
       2015 (includes corresponding Graph/Chart)                       125


       Table 41: UK Historic Review for Cell/Tissue Culture
       Supplies by Product Segment - Media, Sera, and Reagents
       Markets Independently Analyzed with Annual Sales Figures in
       US$ Million for Years 2011 through 2015 (includes
       corresponding Graph/Chart) (includes corresponding
       Graph/Chart)                                    126


       Table 42: UK 11-Year Perspective for Cell/Tissue Culture
       Supplies by Product Segment - Percentage Breakdown of Dollar
       Sales for Media, Sera, and Reagents Markets for Years 2005,
       2010 & 2015 (includes corresponding Graph/Chart)                    126


 16e. REST OF EUROPE                                             127
     A.Market Analysis                                   127
       Current & Future Analysis                               127
       Scenario in other European Countries                          127
     B.Market Analytics                                  128
       Table 43: Rest of Europe Recent Past, Current & Future
       Analysis for Cell/Tissue Culture Supplies by Product Segment -
       Media, Sera, and Reagents Markets Independently Analyzed
       with Annual Sales Figures in US$ Million for Years 2007
       through 2015 (includes corresponding Graph/Chart)                   128


       Table 44: Rest of Europe Historic Review for Cell/Tissue
       Culture Supplies by Product Segment - Media, Sera, and
       Reagents Markets Independently Analyzed with Annual Sales
       Figures in US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                               129




Global Cell/Tissue Culture Supplies Industry                                                                       Page 13/17
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ReportLinker                                                                        and Market Statistics


       Table 45: Rest of Europe 11-Year Perspective for Cell/Tissue
       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera and Reagent Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)          130


 17. ASIA-PACIFIC                                          131
     A.Market Analysis                                     131
       Current & Future Analysis                             131
       Rise of Cell Culture in Asia                         131
       India                                       131
        Cell Culture Market Constituents                         131
       China                                        132
       Taiwan                                        132
       Australia                                    132
     B.Market Analytics                                    133
       Table 46: Asia-Pacific Recent Past, Current & Future
       Analysis for Cell/Tissue Culture Supplies by Product Segment -
       Media, Sera, and Reagents Markets Independently Analyzed
       with Annual Sales Figures in US$ Million for Years 2007
       through 2015 (includes corresponding Graph/Chart)               133


       Table 47: Asia-Pacific Historic Review for Cell/Tissue
       Culture Supplies by Product Segment - Media, Sera, and
       Reagents Markets Independently Analyzed with Annual Sales
       Figures in US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                                134


       Table 48: Asia-Pacific 11-Year Perspective for Cell/Tissue
       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera and Reagent Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)          135


 18. LATIN AMERICA                                           136
     A.Market Analysis                                     136
       Current & Future Analysis                             136
       Brazilian Biotech Industry                           136
     B.Market Analytics                                    137
       Table 49: Latin American Recent Past, Current & Future
       Analysis for Cell/Tissue Culture Supplies by Product Segment -
       Media, Sera, and Reagents Markets Independently Analyzed
       with Annual Sales Figures in US$ Million for Years 2007
       through 2015 (includes corresponding Graph/Chart)               137


       Table 50: Latin American Historic Review for Cell/Tissue
       Culture Supplies by Product Segment - Media, Sera, and
       Reagents Markets Independently Analyzed with Annual Sales
       Figures in US$ Million for Years 2000 through 2006 (includes
       corresponding Graph/Chart)                                138


       Table 51: Latin American 11-Year Perspective for Cell/Tissue


Global Cell/Tissue Culture Supplies Industry                                                                   Page 14/17
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ReportLinker                                                                        and Market Statistics


       Culture Supplies by Product Segment - Percentage Breakdown
       of Dollar Sales for Media, Sera and Reagent Markets for
       Years 2005, 2010 & 2015 (includes corresponding Graph/Chart)          139



COMPETITION


    Total Companies Profiled: 131 (including Divisions/Subsidiaries - 151)


    ------------------------------------------
    Region/Country                                 Players
    ------------------------------------------
    The United States                                   89
    Canada                                         4
    Japan                                      2
    Europe                                     45
     France                                    2
     Germany                                       10
     The United Kingdom                                     19
     Spain                                     1
     Rest of Europe                                    13
    Asia-Pacific (Excluding Japan)                               7
    Latin America                                      1
    Middle East                                    3
    ------------------------------------------




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Global Cell/Tissue Culture Supplies Industry

  • 1. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Global Cell/Tissue Culture Supplies Industry Published on October 2010 Report Summary This report analyzes the worldwide markets for Cell/Tissue Culture Supplies in US$ Million by the following Product Segments: Media, Sera, and Reagents. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, and Latin America. Annual estimates and forecasts are provided for the period 2007 through 2015. A seven-year historic analysis is also provided for these markets.The report profiles 131 companies including many key and niche players such as Affymetrix, Inc., AMRESCO, Inc., BD Biosciences, Cell Culture Technologies, LLC, Cell Essentials, Inc., Irvine Scientific, Life Technologies Corporation, Lonza Biologics Plc, Mediatech, Inc., Millipore Corporation, Medi-Cult A/S, MP Biomedicals, PerBio Science AB, PromoCell GmbH, Sera Laboratories International, Sigma-Aldrich Corporation, SAFC Biosciences, and Vitrolife AB. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources. Table of Content CELL/TISSUE CULTURE SUPPLIES MCP-3538 A GLOBAL STRATEGIC BUSINESS REPORT CONTENTS 1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS 1 Study Reliability and Reporting Limitations 1 Disclaimers 2 Data Interpretation & Reporting Level 2 Quantitative Techniques & Analytics 3 Product Definitions and Scope of Study 3 Cell/Tissue Culture Media, Sera and Reagents 3 2. MARKET DYNAMICS 5 Outlook 5 Biopharmaceutical Drugs Fuel Cell Culture Market 5 Market Scenario 6 Industrial vs. Academic 6 Biotechnology Sector - Affected by Collapse of Capital Market 6 Global Market Analysis 6 Market Structure 7 3. TRENDS AND ISSUES 8 Global Cell/Tissue Culture Supplies Industry Page 1/17
  • 2. Find Industry reports, Company profiles ReportLinker and Market Statistics US Government's Policies to Boost Cell Culture Market 8 Surging Demand for Cell Culture Products 8 Stem Cells and Vaccines - Key Drivers 8 Growing Acceptance for Hi-Veg Culture Media 8 Fed-Batch Cultures - a Big Hit with Large-Scale Bioprocessors 9 Changing Trend Towards Serum-Free Media 9 Proteomics and Pharmacokinetics to Drive Market Growth 9 Bioresearch and Cell Culture in Protein-Based Drug Development 10 CHO, Hybridomas and Mabs Dominate Mammalian Cell Culture 11 Sluggish Fetal Bovine Serum Market 11 Specialty Media Demand on Rise 11 Emerging Alternatives to Conventional Serum Supplemented Media 12 Growth of Defined Media 12 Regulations Prompt Change in Trends 12 Media Optimization 12 Cell-Line Engineering Vs. Cell Culture Media 12 Other Trends 13 Underlying Threat to Cell Culture Industry 13 Manufacture-on-Demand: Gaining Momentum 13 Move Towards Contract Manufacturing 13 Factors Impacting Growth 14 Business Models Driving the Need for Contract Manufacturing 14 Trends in Contract Manufacturing 14 Target Sectors for Contract Manufacturers 14 4. END-USE ANALYSIS 16 End-Use Applications 16 Cell Therapy 16 Growing by Leaps and Bounds 16 Cell Therapy Applications 17 Key Factors Affecting the Cell Therapy Market 17 Future Trends 17 Related Market Sectors 17 Progenitor Cell Therapy 17 Stem Cell Therapy 18 Other Related Technologies 19 Somatic Cell Nuclear Transfer (SCNT) 19 Tissue Engineering 19 End Use Industries 19 5. CELL/TISSUE CULTURE: PHYSIOLOGICAL OVERVIEW 20 Introduction 20 History 20 Plant Cell and Tissue Culture (PCTC) 24 Cell/Tissue Culture Media, Sera and Reagents 27 Classical Media 27 Specialty Media 28 Serum 28 Fetal Bovine Serum 28 Serum-Free Media 28 Global Cell/Tissue Culture Supplies Industry Page 2/17
  • 3. Find Industry reports, Company profiles ReportLinker and Market Statistics Cell Culture Reagents 29 Role of Tissue Culture in the Growth of Cell Types 29 Equipment 29 Storage and Preservation 29 Maintenance 30 Growth Pattern 30 Harvesting 30 Media and Growth Requirements 31 Physiological Parameters 31 Medium Requirements (Often Empirical) 31 Feeding 31 Safety Precautions 31 Methods of Tissue Culture 32 Preparation of Media 32 Growth and Morphology 32 Sub Culturing Adherent Cells 32 Thawing Frozen Cells 32 Freezing Cells 32 Cell Culture Contamination - A Looming Problem 33 Classification 33 Major Cell Culture Contaminants 33 Chemical Contamination 33 Types and Sources of Potential Chemical Contaminants 33 Varied Sources of Chemical Contamination 34 Media and Components 34 Sera 34 Water 35 Storage Vessels 35 Fluorescent Lights 35 Endotoxins 35 Incubators 36 Biological Contamination 36 Varied Sources of Biological Contamination 37 Mycoplasmas 37 Airborne Particles and Aerosols 37 Cross Contamination by Other Cell Cultures 38 Consequences/Problems of Contamination 38 Controlling Cell Culture Contamination 38 Measures Aimed at Reducing Contamination Problems 39 6. REGULATORY ENVIRONMENT 40 7. PRODUCT INNOVATIONS/INTRODUCTIONS 41 StemCells Introduces GS1-R' 41 Kollodis BioSciences Introduces Cell-Culture Reagents 41 The Automation Partnership Launches Automated Cell-Culture 41 Novartis Receives Approval to Release its New Vaccine 42 Invitrogen Introduces GIBCO® OpTmizer TM T-cell Expansion SFM 42 Novozymes Biopharma Rolls Out CellPrime in Partner ship with Millipore 42 Global Cell/Tissue Culture Supplies Industry Page 3/17
  • 4. Find Industry reports, Company profiles ReportLinker and Market Statistics Invitrogen Launches Dynabeads® SSEA-4 43 Invitrogen Rolls Out KNOCKOUTTM SR XenoFree Media 43 Lonza Develops One-Step Program 43 Millipore Unveils ESGRO CompleteTM PLUS Medium 43 Millipore Introduces Hanging Millicell® Cell Culture Inserts 43 SAFC Biosciences® Launches EX-CELLTM EBx® 44 SAFC Biosciences® Rolls Out EX-Fusion and CHO Library 44 Millipore Launches Epidermal Keratinocyte 3D Medium 44 Invitrogen Rolls Out PD-Direct® Bioprocess Services 45 Millipore Unveils a New Variety of Primary Human Epithelial Cells 45 BD Biosciences Introduces BD Analysis Kit 46 Thermo Fisher Scientific Rolls Out Thermo Clone 46 Lonza Introduces Poietics® Human Natural Killer (NK) Cells 46 Millipore Launches New MillicoatTM Cultureware 47 Millipore Unveils High Content Analysis Kits 47 Millipore Rolls Out FlowCellect' 47 Invitrogen Introduces GIBCO® Bottles 47 Invitrogen Unveils ST SFM, STEO and STEA Differentiation Kits 48 Thermo Fisher Scientific Launches NuncTM UpCellTM Surface 48 Millipore Releases New Primary Human Epithelial Cell Cultures 48 Millipore Expands Stem Cell Tested Initiative 49 BD Biosciences Debuts BD FACSAria' II System to Sort Cells 49 Invitrogen Introduces Specific SFM for the Mesenchymal Stem Cells 49 StemCell Launches Cryopreservation Medium Free from Serum 50 Invitrogen Unveils SequalPrep' System 50 Invitrogen Introduces Animal Source-Free Substrate 50 Invitrogen Introduces GIBCO® FoamAway' Reagent 50 Genetix Develops New CytoGenetix Reagents and Kits 51 8. PRODUCT INTRODUCTIONS/INNOVATIONS IN THE RECENT PAST - A PERSPECTIVE BUILDER 52 Thermo Fisher Launches NUNC In Vitro PDL Coated PETG Roller Bottles 52 Thermo Fisher Scientific Introduces HyClone AdvanceSTEM' Cell Culture Product Line 52 Thermo Fisher Scientific Introduces New Medium to Culture PER .C6 Cell Line 52 Genetix Expands CloneMedia Semi-Solid Media Products 52 Invitrogen Launches STEMPRO® EZPassage' Tool 53 Sigma-Aldrich Introduces GenomePlex Tissue WGA Kit 53 Thermo Fisher Scientific Introduces Two New Versatile Media for HEK 293 Cell Line 53 SAFC Biosciences Launches LONG®R3IGF-I in Liquid Form 53 Invitrogen and Novocell Introduce Media for hESC Growth 54 Invitrogen Releases New Culture System 54 Invitrogen Introduces New Line of Engineered Stem Cells 54 BD Biosciences Partners with StemCell Technologies 54 Millipore Launches MEL Cell Lines 55 Irvine Scientific Expands Industrial Cell Culture Product Line 55 Biovest International Introduces Automated Cell Culture Device 55 Global Cell/Tissue Culture Supplies Industry Page 4/17
  • 5. Find Industry reports, Company profiles ReportLinker and Market Statistics BD Biosciences Introduces BD FACSDiva' 6.0 Software 56 Millipore Unveils Nylon Net Steriflip® Filter Unit 56 Lonza Expands Product-Portfolio with Serum Free Media 56 MediCult Unveils Flexible Culture Systems, BlastAssist® and EmbryoAssist' 56 Millipore Introduces New Medium for Human Embryonic Stem Cell Research 57 Invitrogen Launches CytoGenie' Cytometry Software Tool 57 Novozymes Releases New Cell Culture Components 57 The Automation Partnership Launches Advanced Plating Module 57 Nikon Unveils BioStation CT 58 Corning Launches Innovative Cell Culture Solutions 58 GroPep Introduces New Assay Kit for Cell Culture Business 58 HyClone Introduces HyQ®CDM4MAb' for Hybridoma Cell Lines 58 INTEGRA Biosciences Adds Alarm Interface to CELLROLL and CELLSPIN Systems 59 Nikon Launches New Imaging and Tracking Systems for Cell Culture 59 Genetix Develops Cell Dispenser 59 SAFC Biosciences Introduces LONGTMR3IGF-I for Industrial Cell Culture 59 Biocrystal Presents Opticell 59 TAP Unveils CompacT SelecT' 60 New Brunswick Scientific Augments New Products to Cell Culture Systems 60 Cell Culture Technologies Develops Fortified Production Media 60 9. RECENT INDUSTRY ACTIVITY 61 Akron Biotechnology Merges with AppliChem 61 ChanTest Takes Over Applied Cell Sciences 61 Millipore to Takeover Guava Technologies 61 Millipore Acquires EpiTagTM Technology from Epitome Biosystems 62 MediCult's BlastAssist® Culture Media Obtains FDA Approval 62 Capsant Signs Commercialization Agreement with VistaGen 62 Millipore Inks Distribution Agreement with Solabia 63 Helix BioMedix Signs Production and Supply Agreement with Peptisyntha 63 BD Biosciences to Establish New Production Facility 63 Lonza Group Takes Over amaxa 64 Millipore and Bayer Healthcare Sign Agreement 64 Applied Biosystems and Invitrogen Merge 64 SAFC BiosciencesTM and Celltrion Enter into Agreement 64 Tata Chemicals to Acquire Stake in Joil 65 Sartorius Stedim Biotech Acquires Wave Biotech 65 Sigma-Aldrich and AlphaGenix Sign Distribution Agreement 65 Induce Biologics and Therapure Biopharma Enter into Collaboration 65 International Stem Cell and Millipore Sign Distribution Agreement 65 Lonza Signs Agreement with Crucell 66 Eden Biodesign and Human Genome Sciences Sign Agreement 66 Becton, Dickinson to Establish New Production Facility 66 MedCell Bioscience Merges with NovaThera 66 Global Cell/Tissue Culture Supplies Industry Page 5/17
  • 6. Find Industry reports, Company profiles ReportLinker and Market Statistics Covidien UK Holding Takes Over Tissue Science Laboratories 67 Invitrogen Establishes Dedicated Business Unit for Cell Therapy 67 Invitrogen Signs Deal to Acquire CellzDirect 67 Invitrogen Renews Agreement with Luminex Corporation 67 BioTime Establishes Tissue Culture Facility 68 International Stem Cell Signs Agreement with ATCC 68 Millipore Signs Agreement with Solabia to Distribute Animal- Free Hydrolysates 68 Affymetrix Acquires USB Corporation 69 SAFC to Expand Production Capacity of Viral Product 69 Lonza Signs Partnership Agreement with Sanofi to Produce Cell Culture Vaccine 69 10. STRATEGIC CORPORATE ACTIVITY IN THE RECENT PAST - A PERSPECTIVE BUILDER 70 SAFC to Increase Fermentation Capabilities of High-Potency API 70 Biogen Offers Contract to Jacobs Engineering Group 70 New Brunswick Scientific Merges with Eppendorf Group 70 Vitrolife Extends Agreement with Cellartis 70 Sigma-Aldrich Inks Distribution Agreement with CellPath 70 Lonza Acquires two Subsidiaries of Cambrex Bio-Businesses 71 Vikdas to Build Biotechnological Laboratory 71 Novartis to Invest in a New Cell Culture Plant in Singapore 71 Invitrogen Signs Agreement with Biocon 71 Lonza and Bio*One form Joint Venture for Mammalian Cell Culture Plant 71 Thermo Fisher to Extend Manufacturing Operations 72 BD Biosciences Announces Treyburn Expansion Plans 72 BD Biosciences Collaborates with Roche to Advance Cell Signal Transduction Study 72 Invitrogen and RXi Pharmaceuticals Enter into Collaboration 73 Millipore Forms a Strategic Alliance with Novozymes 73 Thermo Fisher Takes Over OptiCell Product Line 73 Invitrogen Collaborates with Cytori for Research on Adipose Stem Cell 73 Thermo Fisher Partners with Cellular Engineering for Stem Cell Research 74 VWR Signs Agreement to Distribute Biovest's Cell Culture Device 74 Genentech Constructs New Cell Culture Plant 74 Invitrogen Signs Deal with Wave Biotech to Offer Media-Filled Disposable Bioreactors 74 MediCult Purchases Humagen Fertility 74 Millipore Acquires Serologicals 75 ReNeuron Inks Collaboration Agreement with CellSeed 75 Trans Valley Launches Tissue Cultured Variety of Mushrooms 75 HiMedia Laboratories Forges Distribution Deal with VWR International 75 Teva Signs Collaboration Agreement with Protalix Biotherapeutics 75 SAFC-Biosciences Forms to Support Sigma-Aldrich 76 Invitrogen and Cellartis to Co-develop hESC Reporter Lines 76 Global Cell/Tissue Culture Supplies Industry Page 6/17
  • 7. Find Industry reports, Company profiles ReportLinker and Market Statistics CELLCA and Rentschler Join Forces for Unique High-Level Expression System 76 ArcDia Partners with Chip-Man Technologies 76 Chugai Pharmaceutical Receives License for Cell Line from Cambrex Bio Science Walkersville, Inc. 76 Chemicon Inks Distribution Agreement with CELLnTEC 77 Chemicon Signs an Agreement with ReNeuron 77 Chemicon to Market Stem Cell Products of ASCC 77 SCS and Chemicon Introduce ESGRO Complete' Product Range 77 Serologicals Acquires Cytomyx Ltd 78 Millipore to Take Over Serologicals 78 CAT Opts SelectT' for Higher Cell Culture Yields 78 11. FOCUS ON SELECT MAJOR PLAYERS 79 Affymetrix, Inc. (USA) 79 AMRESCO, Inc. (USA) 79 BD Biosciences (USA) 79 Cell Culture Technologies, LLC (Switzerland) 80 Cell Essentials, Inc. (USA) 80 Irvine Scientific (USA) 80 Life Technologies Corporation (USA) 80 Lonza Biologics Plc (UK) 81 Mediatech, Inc. (USA) 81 Millipore Corporation (USA) 81 Medi-Cult A/S (Denmark) 81 MP Biomedicals (USA) 82 PerBio Science AB (Sweden) 82 PromoCell GmbH (Germany) 82 Sera Laboratories International (UK) 82 Sigma-Aldrich Corporation (USA) 83 SAFC Biosciences (USA) 83 Vitrolife AB (Sweden) 83 12. GLOBAL MARKET PERSPECTIVE 84 Table 1: World Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 84 Table 2: World Historic Review for Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 85 Table 3: World 11-Year Perspective for Cell/Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Global Cell/Tissue Culture Supplies Industry Page 7/17
  • 8. Find Industry reports, Company profiles ReportLinker and Market Statistics Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) & Latin America Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 86 Cell/Tissue Culture Supplies Market by Product Segment 87 Table 4: World Recent Past, Current & Future Analysis for Media Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 87 Table 5: World Historic Review for Media Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 88 Table 6: World 11-Year Perspective for Media Cell/Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) & Latin America Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 89 Table 7: World Recent Past, Current & Future Analysis for Sera Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 90 Table 8: World Historic Review for Sera Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 91 Table 9: World 11-Year Perspective for Sera Cell/Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) & Latin America Markets for Years2005, 2010 & 2015 (includes corresponding Graph/Chart) 92 Table 10: World Recent Past, Current & Future Analysis for Reagent Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 93 Global Cell/Tissue Culture Supplies Industry Page 8/17
  • 9. Find Industry reports, Company profiles ReportLinker and Market Statistics Table 11: World Historic Review for Reagent Cell/Tissue Culture Supplies by Geographic Region - USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) and Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 94 Table 12: World 11-Year Perspective for Reagent Cell/ Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for USA, Canada, Japan, Europe, Asia-Pacific (excluding Japan) & Latin America Markets for Years2005, 2010 & 2015 (includes corresponding Graph/Chart) 95 13. THE UNITED STATES 96 A.Market Analysis 96 Current & Future Analysis 96 Cell & Tissue Culture Market 96 A Brief Insight 96 Market Trends 97 Trend Towards Serum-Free Media 97 Liquid and Powdered Media Account for Major Share 97 Table 13: Leading Players in the US Cell Culture Media Market (2008): Percentage Breakdown of Sales for - Sigma-Aldrich, Hyclone, Lonza Biologics, and Others (includes corresponding Graph/Chart) 97 Fetal Bovine Serum - On A Decline 98 Rise in Cell Culture Equipment Demand Leads to Innovation 98 Market for Stem Cell Research 98 End-Use Analysis 99 Table 14: US Market for Cell Culture Reagents by End Use - Academic, Industrial, and Non-Academic (2008) (includes corresponding Graph/Chart) 99 Factors Influencing the Market for Tissue and Cell Culture Media 99 Regulatory Controls 99 Guidelines Governing Use of Cell/Tissue Culture Reagents 100 MSDS and Hazardous Information 100 Toxic Substances Control Act 100 B.Market Analytics 101 Table 15: US Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 101 Table 16: US Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes Global Cell/Tissue Culture Supplies Industry Page 9/17
  • 10. Find Industry reports, Company profiles ReportLinker and Market Statistics corresponding Graph/Chart) 102 Table 17: US 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 103 14. CANADA 104 A.Market Analysis 104 Current & Future Analysis 104 Biotechnology Industry 104 B.Market Analytics 105 Table 18: Canadian Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 105 Table 19: Canadian Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 106 Table 20: Canadian 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 106 15. JAPAN 107 A.Market Analysis 107 Current & Future Analysis 107 B.Market Analytics 107 Table 21: Japanese Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 107 Table 22: Japanese Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 108 Table 23: Japanese 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 108 Global Cell/Tissue Culture Supplies Industry Page 10/17
  • 11. Find Industry reports, Company profiles ReportLinker and Market Statistics 16. EUROPE 109 A.Market Analysis 109 Current & Future Analysis 109 Market Overview 109 B.Market Analytics 110 Table 24: European Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Geographic Region - France, Germany, UK, Italy & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 110 Table 25: European Historic Review for Cell/Tissue Culture Supplies by Geographic Region - France, Germany, UK, Italy and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 111 Table 26: European Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 112 Table 27: European Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 113 Table 28: European 11-Year Perspective for Cell/Tissue Culture Supplies by Geographic Region - Percentage Breakdown of Dollar Sales for France, Germany, UK, Italy & Rest of Europe Markets for Years2005, 2010 & 2015 (includes corresponding Graph/Chart) 114 Table 29: European 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 115 16a. FRANCE 116 Market Analysis 116 Current & Future Analysis 116 Table 30: French Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 116 Global Cell/Tissue Culture Supplies Industry Page 11/17
  • 12. Find Industry reports, Company profiles ReportLinker and Market Statistics Table 31: French Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 117 Table 32: French 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 117 16b. GERMANY 118 A.Market Analysis 118 Current & Future Analysis 118 Biotech Research Scenario 118 Table 33: German Biotech Market (2009): Percentage Breakdown by Application Area - Environment, Human Health Care, Chemical industry, Food, Agriculture, Energy, and Others (includes corresponding Graph/Chart) 119 B.Market Analytics 119 Table 34: German Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 119 Table 35: German Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 120 Table 36: German 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years2005, 2010 & 2015 (includes corresponding Graph/Chart) 120 16c. ITALY 121 Market Analysis 121 Current & Future Analysis 121 Table 37: Italian Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 121 Table 38: Italian Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes Global Cell/Tissue Culture Supplies Industry Page 12/17
  • 13. Find Industry reports, Company profiles ReportLinker and Market Statistics corresponding Graph/Chart) 122 Table 39: Italian 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 122 16d. THE UNITED KINGDOM 123 A.Market Analysis 123 Current & Future Analysis 123 Biotechnology Industry - A Brief Insight 123 Regulatory Issues 124 HFE Act Guidelines 124 The Ethical Issues 124 B.Market Analytics 125 Table 40: UK Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 125 Table 41: UK Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart) (includes corresponding Graph/Chart) 126 Table 42: UK 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera, and Reagents Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 126 16e. REST OF EUROPE 127 A.Market Analysis 127 Current & Future Analysis 127 Scenario in other European Countries 127 B.Market Analytics 128 Table 43: Rest of Europe Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 128 Table 44: Rest of Europe Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 129 Global Cell/Tissue Culture Supplies Industry Page 13/17
  • 14. Find Industry reports, Company profiles ReportLinker and Market Statistics Table 45: Rest of Europe 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera and Reagent Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 130 17. ASIA-PACIFIC 131 A.Market Analysis 131 Current & Future Analysis 131 Rise of Cell Culture in Asia 131 India 131 Cell Culture Market Constituents 131 China 132 Taiwan 132 Australia 132 B.Market Analytics 133 Table 46: Asia-Pacific Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 133 Table 47: Asia-Pacific Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 134 Table 48: Asia-Pacific 11-Year Perspective for Cell/Tissue Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera and Reagent Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 135 18. LATIN AMERICA 136 A.Market Analysis 136 Current & Future Analysis 136 Brazilian Biotech Industry 136 B.Market Analytics 137 Table 49: Latin American Recent Past, Current & Future Analysis for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2015 (includes corresponding Graph/Chart) 137 Table 50: Latin American Historic Review for Cell/Tissue Culture Supplies by Product Segment - Media, Sera, and Reagents Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2006 (includes corresponding Graph/Chart) 138 Table 51: Latin American 11-Year Perspective for Cell/Tissue Global Cell/Tissue Culture Supplies Industry Page 14/17
  • 15. Find Industry reports, Company profiles ReportLinker and Market Statistics Culture Supplies by Product Segment - Percentage Breakdown of Dollar Sales for Media, Sera and Reagent Markets for Years 2005, 2010 & 2015 (includes corresponding Graph/Chart) 139 COMPETITION Total Companies Profiled: 131 (including Divisions/Subsidiaries - 151) ------------------------------------------ Region/Country Players ------------------------------------------ The United States 89 Canada 4 Japan 2 Europe 45 France 2 Germany 10 The United Kingdom 19 Spain 1 Rest of Europe 13 Asia-Pacific (Excluding Japan) 7 Latin America 1 Middle East 3 ------------------------------------------ Global Cell/Tissue Culture Supplies Industry Page 15/17
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