Austin Journal of Biosensors & Bioelectronics is an open access, peer reviewed, scholarly journal dedicated to publish articles related to original and novel fundamental research in the field of Biomarkers Research. The aim of the journal is to provide a platform for research scholars, scientists and other professionals to find most original research in the field Biosensors & Bioelectronics. Austin Journal of Biosensors & Bioelectronics accepts original research articles, review articles, case reports and short communication on all the aspects of Biosensors & Bioelectronics and its Research

1. BIOSENSORS

2. BIOSENSOR?
Biosensor is an analytical device which utilize
reaction of biochemical molecule for detecting
target analyte and converts a biological response
into a quantifiable and processable signal
or
A sensor that integrates a biological element
with a physiochemical transducer to
produce an electronic signal proportional to
a single analyte which is then conveyed to a
detector

3. FATHER OF BIOSENSOR
Professor Leland C Clark
Jnr 1918–2005

4. HISTORY OF BIOSENSORS

5. Analyte
Sample
handling/
preparation
Detection
Signal
Analysis
Response
PARTS OF A BIOSENSOR

6. DETECTOR
WORKING OF BIOSENSOR

7. 1. LINEARITY – Linearity of the sensor should
be high for the detection of high substrate
concentration.
2. SENSITIVITY - Value of the electrode
response per substrate concentration.
3. SELECTIVITY - Chemicals Interference must
be minimized for obtaining the correct result.
4.RESPONSE TIME – Time necessary for
having 95% of the response.
CHARACTERISTICS OF A BIOSENSOR

8. 1. Calorimetric Biosensor
2. Potentiometric Biosensor
3. Optical Biosensor
4. Piezo-electric Biosensor
5. Amperometric biosensor
TYPES OF BIOSENSORS

9. If the enzyme catalyzed reaction is exothermic,
two thermistors may be used to
measure the difference in resistance
between reactant and product and, hence,
the analyte concentration.
1.CALORIMETRIC BIOSENSORS

10. 2. POTENTIOMETRIC
BIOSENSORS
For voltage: Change in
distribution of charge is detected
using ion-selective electrodes,
such as pH-meters.

11.  Colorimetric for color :
Measure change in light adsorption
 Photometric for light intensity :
Photon output for a luminescent or fluorescent
process can be detected with photomultiplier
tubes or photodiode systems.
3. OPTICAL BIOSENSOR

12. 4. PIEZO-ELECTRIC
BIOSENSOR
Piezo-electric devices use gold to detect the
specific angle at which electron waves are
emitted when the substance is exposed to
laser light or crystals, such as quartz, which
vibrate under the influence of an electric
field.

13. Pregnancy test
Glucose monitoring device
Infectous disease biosensor from RBS
Coal miners’ biosensor
EXAMPLES OF BIOSENSORS

14. DRAWBACKS OF BIOSENSORS
Time consuming
Complicated
Labor intensive procedure
Expensive
Narrow target quantization

15.  Food Analysis
 Study of biomolecules and their interaction
 Drug Development
 Crime detection
 Medical diagnosis
 Environmental field monitoring
 Quality control
 Industrial Process Control
 Detection systems for biological warfare agents
 Manufacturing of pharmaceuticals and replacement organs
APPLICATIONS OF
BIOSENSORS