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Developing Countries Operating Unit
1st Euro-Africa Health Investment Conference: MediPharm, March 26-27,
London

Craig Williams
Director, Vaccines and Disease of the Developing World
The DC operating unit

Established in August 2010 - to increase
patient access to GSK medicines and
vaccines while expanding its presence
and helping it build a sustainable
business in developing countries

Tasked with bringing a dedicated GSK
focus to expanding access to medicines
for around 800 million people in the
world’s least developed countries
(LDCs)
The Markets

Covers 50 countries, 49 defined by
UN as least developed, over half of
whom survive on less than $1 a day

currently supply medicines to 37 of
the 49 LDCs and employ 650
people across the unit.
GSK’s operating model in
Developing Countries
Lower price/higher volume

Volume incentive
Longer-term return on investment
Patented medicines & vaccines capped
at 25% of UK price

20% of profit reinvested in healthcare
infrastructure in country)

The target is a five-fold growth in
volume of medicines & vaccines supplied
to these countries by 2015.
Strategy

1. Vaccines
2. Product Registration/Portfolio Expansion
3. Healthcare Infrastructure

4. People
Vaccines- GAVI
 Vaccines: For over 20 years we have made our entire vaccine portfolio
available for expanded immunisation programmes at preferential prices to
developing countries using a tiered pricing system.

 GAVI Pledging Meeting – 13 June 2011
– Initial target : $3.7 billion
– Donors commitment : $4.3 billion
– Resources available for 2011-2015 : $7.6 billion
Health Infrastructure -Our commitment to reinvest
20% of profits
 GSK partner with AMREF, CARE
International and Save The Children to
strengthen healthcare infrastructure in
LDCs
 To increase the numbers of trained
healthcare workers in rural and
marginalised communities
 A sustainable model to improve
healthcare infrastructure in developing
countries
 Supporting community healthcare
workers increases access to medicines
and ultimately improves health
outcomes
Health Infrastructure - One Family Health

 Nurse run Franchise clinic network
 Currently 80 clinics in Kenya serving

500,000 patients per year
 GSK announced expansion for Rwanda
in April to establish 250 health posts over
the next three years
Health Infrastructure – Anti counterfeiting Nigeria
Using SMS text technology to guarantee the quality of products

GSK added a scratch off panel on the packs to include a unique code. Patients
would then text in the code (free) to a central number to authenticate the product.
Access to Medicines Contributions

R&D

• R&D PPPs
• WIPO Research
• Open lab
• Malaria screen
• HIV
• TB, malaria
• Trust in Science (LATAM &
AFRICA)

New Business Models

• Tiered pricing
• ViiV Healthcare
• DCMA unit
• CME
• Voluntary licensing
• Portfolio
• Branded generics
• Small pack sizes
• EMAP R&D

• Techonolgy transfer
• Brazil JV

• Innovative pricing
• Malaria
• AMC

Health
Systems

• 20% reinvestment
• LF elimination
• African malaria
Partnership
• PHASE
• Positive Action and PAFC
• Humanitarian relief
• De-worming programme
GSK retained ATM leadership in 2012
Paper presented by GSK's Developing Countries Operating Unit

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Paper presented by GSK's Developing Countries Operating Unit

  • 1. Developing Countries Operating Unit 1st Euro-Africa Health Investment Conference: MediPharm, March 26-27, London Craig Williams Director, Vaccines and Disease of the Developing World
  • 2. The DC operating unit Established in August 2010 - to increase patient access to GSK medicines and vaccines while expanding its presence and helping it build a sustainable business in developing countries Tasked with bringing a dedicated GSK focus to expanding access to medicines for around 800 million people in the world’s least developed countries (LDCs)
  • 3. The Markets Covers 50 countries, 49 defined by UN as least developed, over half of whom survive on less than $1 a day currently supply medicines to 37 of the 49 LDCs and employ 650 people across the unit.
  • 4. GSK’s operating model in Developing Countries Lower price/higher volume Volume incentive Longer-term return on investment Patented medicines & vaccines capped at 25% of UK price 20% of profit reinvested in healthcare infrastructure in country) The target is a five-fold growth in volume of medicines & vaccines supplied to these countries by 2015.
  • 5. Strategy 1. Vaccines 2. Product Registration/Portfolio Expansion 3. Healthcare Infrastructure 4. People
  • 6. Vaccines- GAVI  Vaccines: For over 20 years we have made our entire vaccine portfolio available for expanded immunisation programmes at preferential prices to developing countries using a tiered pricing system.  GAVI Pledging Meeting – 13 June 2011 – Initial target : $3.7 billion – Donors commitment : $4.3 billion – Resources available for 2011-2015 : $7.6 billion
  • 7. Health Infrastructure -Our commitment to reinvest 20% of profits  GSK partner with AMREF, CARE International and Save The Children to strengthen healthcare infrastructure in LDCs  To increase the numbers of trained healthcare workers in rural and marginalised communities  A sustainable model to improve healthcare infrastructure in developing countries  Supporting community healthcare workers increases access to medicines and ultimately improves health outcomes
  • 8. Health Infrastructure - One Family Health  Nurse run Franchise clinic network  Currently 80 clinics in Kenya serving 500,000 patients per year  GSK announced expansion for Rwanda in April to establish 250 health posts over the next three years
  • 9. Health Infrastructure – Anti counterfeiting Nigeria Using SMS text technology to guarantee the quality of products GSK added a scratch off panel on the packs to include a unique code. Patients would then text in the code (free) to a central number to authenticate the product.
  • 10. Access to Medicines Contributions R&D • R&D PPPs • WIPO Research • Open lab • Malaria screen • HIV • TB, malaria • Trust in Science (LATAM & AFRICA) New Business Models • Tiered pricing • ViiV Healthcare • DCMA unit • CME • Voluntary licensing • Portfolio • Branded generics • Small pack sizes • EMAP R&D • Techonolgy transfer • Brazil JV • Innovative pricing • Malaria • AMC Health Systems • 20% reinvestment • LF elimination • African malaria Partnership • PHASE • Positive Action and PAFC • Humanitarian relief • De-worming programme
  • 11. GSK retained ATM leadership in 2012

Editor's Notes

  1. “Instead of making £1 million profit by supplying 100,000 patients, we want to make £1 million profit by supplying one million patients. This should translate into a sustainable health impact.” The unit’s ultimate goal – to be part of the solution, rather than simply sit back and wait for things to change
  2. One family health is a private enterprise which has developed the “CFW” (Child and Family Wellness) franchise system for a local nurse to own and operate a basic medical clinic in rural and slum areas of Africa. CFWfranchisees receive franchisor support to succeed in business and build the CFWbrand: Start-up loans, Initial training , Ongoing coaching, System-wide marketing support, Peer network and recognition, Technology innovationsCFWclinics target the short list of diseases and conditions causing approximately 70% of illness and death in local communities (e.g. malaria, diarrheal disease, respiratory infections). CFWmaintains a secure supply chain of high-quality, affordable essential medicines in places where counterfeit and substandard drugs are rampant.Patients trust CFWfranchisees because they are qualified, accessible, convenient, affordable, and provide quality careCFWfranchisees also distribute preventive messages and health education to local communities and schoolsCurrently 80 clinics in Kenya serving 500,000 patients per yearIn April 2012 announced partnership which brings together One Family Health (OFH) Foundation, GSK, Ecobank and the Rwandan Ministry of Health in a coordinated effort to establish up to 250 health posts across Rwanda over the next three years. With support from the Ministry of Health, this innovative partnership aims to increase access to high quality essential medicines and basic healthcare for around two million people per year in rural and marginalised communities in Rwanda. )
  3. Nigeria Market SMS trial (March – August 2011) In Nigeria we have trialled an SMS service in partnership with the country’s National Agency for Food, Drug, Administration and Control (NAFDAC) using their text number. Ampiclox, one of Nigeria’s highest selling SKU’s is threatened by counterfeit activity. GSK added a scratch of panel on the packs to include a unique code. Patients would then text in the code (free) to a central number to authenticate the product. The SMS Service responds if code is recognised and if there were any issues patients could contact an SMS helpline. Third party SMS service implemented in partnership with the country’s National Agency for Food, Drug, Administration and Control (NAFDAC) using their text numberSingle SKU (Ampiclox), one of Nigeria’s highest selling SKU’s threatened by counterfeit activity - (planned 1.7m Blisters)1. Customer buys labelled product from Vendor- 2. Customer Texts Hidden Code to SMS Service (free) - 3. SMS Service Responds if Code Recognised - 4. If issue contact SMS Help Line If successful it may be extended to other countriesConducted an awareness campaign for consumers and supply chainEnd June 11 statistics - 145,000 texts115,000 unique users10% of sales sent texts90% of texts receive genuine message7.5% of texts receive duplicate PIN message2.5% of texts receive a fake message2,369 calls to the Helpdesk of which 30 have been escalated to GSK1 successful product retrieval