The document summarizes the history of discovering fetal alcohol syndrome (FAS) in 5 phases from 1973 to the early 2000s. It describes how Dr. Smith and Dr. Jones first discovered the pattern of malformations in children born to alcoholic mothers in 1973. It then discusses the crusade in the late 1970s and 1980s to warn about the risks of drinking during pregnancy. The third phase discusses debates around legal and social responsibility. Phase four discusses debates around prosecuting pregnant women. Phase five suggests developing a comprehensive response that addresses substance use in pregnancy.