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Dr Pallab Kanti NathDr Pallab Kanti Nath
MD AnaesthesiologyMD Anaesthesiology
Basic level class for technicians
Five Senses
Vision (Sight)
Smell (olfaction)
Taste
Touch
Hearing
Equilibrium is also considered a special sense, found in
the ear
Taste (Gustation)
Taste buds are found in papillae of the tongue mucosa
Papillae - three types: filiform, fungiform, and
circumvallate
Fungiform and circumvallate papillae contain taste buds
Appx 10,000 taste buds - each taste bud has 40-100
epithelial cells made of 3 major types:
 Supporting Cells: separate and insulate
 Receptor Cells: deal with taste
 Basal cells: like stem cells, they give rise to new cells
Taste Buds
Taste Sensation
• There are five basic taste sensations
– Sweet – sugars, saccharin, alcohol, and
some amino acids
– Salt – metal ions
– Sour – hydrogen ions
– Bitter – alkaloids such as quinine and
nicotine
– Umami – elicited by the amino acid
glutamate
Activation
 To be tasted, first must be dissolved in saliva, diffuse into the
pore and make contact with gustatory hairs which trigger
neurotransmitters to elicit action potentials in these fibers.
 Adapt rapidly 3-5 seconds & completely in 1-5 minutes
Taste Transduction
 Process in which stimulus energy is converted into a nerve
impulse due to influx of different ions
Physiology of Taste
Taste is carried by two cranial nerves
 Facial: anterior 2/3rds of tongue
 Glossopharyngeal: posterior 1/3rd
 Taste triggers reflexes in digestion such as increasing saliva &
gastric juice
Gustatory Pathway
Influence of other sensations on taste
•Taste is 80% smell, when olfactory
receptors are blocked food becomes
bland
•Thermoreceptors, mechanoreceptors,
nociceptors, temperature and texture can
enhance or detract
Sense of Smell (Olfaction)
• The organ of smell is the olfactory epithelium,
which covers the superior nasal concha
• Olfactory receptor cells are bipolar neurons with
radiating olfactory cilia
• Olfactory receptors are surrounded and cushioned
by supporting cells
• Basal cells lie at the base of the epithelium
Olfactory epithelium
Detects chemicals in solution
Covered by mucous to trap airborne molecules
Physiology
Substance must be in a gaseous state
Must be water soluble to dissolve in olfactory epithelium
Bind to protein receptors which open ion channels that send action
potentials to olfactory bulb
Pathway
Send impulses from bulb down tract
Thalmus  Frontal Lobe or Hypothalmus to interpret and elicit
emotional responses to odor
Imablances include anosmia (without smells) from head injuries; unicinate
fits (olfactory hallucinations)
Olfaction
Vision
Accessory Structures
Eyebrows
Shade the eyes
Prevent perspiration into eye
Eyelids
Palpabrae protects eye
Levator palpebrae superioris raises eyelid
Eyelashes trigger blinking
Conjunctiva
Mucous membrane over eyelids and anterior
surface of eyeball (white part)
Vascular, when irritated eyes are blood shot
Extraocular muscles
 Movement is controlled by 6 muscles
 Four Rectus muscles: Superior,
Inferior, Lateral, Medial
 Two Oblique muscles: Superior,
Inferior
 Nerve Innervation: abducens,
trochlear, oculomotor
Lens : Divides eye into anterior
and posterior segments
 Transparent, flexible structure that
can change shape to allow focus of
light on retina
 Avascular
 Becomes less elastic through life
causing focus impairment
 Cataract – cloudy lens due to
thickening of lens or diabetes
Extra ocular muscles
Lacrimal Apparatus
• Consists of the lacrimal gland and
associated ducts
• Lacrimal glands secrete tears
• Tears
– Contain mucus, antibodies, and lysozyme
– Enter the eye via superolateral excretory
ducts
– Exit the eye medially via the lacrimal
punctum
– Drain into the nasolacrimal duct
Lacrimal Apparatus
Structure of the Eyeball
Fibrous Tunic
• Forms the outermost coat of the eye and is
composed of:
– Opaque sclera (posteriorly)
– Clear cornea (anteriorly)
• The sclera protects the eye and anchors
extrinsic muscles
• The cornea lets light enter the eye
Vascular Tunic (Uvea)
• Has three regions: choroid, ciliary
body, and iris
• Choroid region
–A dark brown membrane that
forms the posterior portion of the
uvea
–Supplies blood to all eye tunics
Vascular Tunic
• A thickened ring of tissue surrounding the
lens
• Composed of smooth muscle bundles
(ciliary muscles)
• Anchors the suspensory ligament that holds
the lens in place
Ciliary Body
• The colored part of the eye
• Pupil – central opening of the iris
– Regulates the amount of light entering the eye
during:
• Close vision and bright light – pupils constrict
• Distant vision and dim light – pupils dilate
• Changes in emotional state – pupils dilate when
the subject matter is appealing or requires
problem-solving skills
Iris
Pupil Dilation and Constriction
Sensory Tunic: Retina
• A delicate two-layered membrane
• Pigmented layer – the outer layer that
absorbs light and prevents its scattering
• Neural layer, which contains:
– Photoreceptors that transduce light energy
– Bipolar cells and ganglion cells
– Amacrine and horizontal cells
Sensory Tunic: Retina
The Retina: Ganglion Cells and the
Optic Disc
• Ganglion cell axons:
– Run along the inner surface of the retina
– Leave the eye as the optic nerve
• The optic disc:
– Is the site where the optic nerve leaves the eye
– Lacks photoreceptors (the blind spot)
The Retina: Ganglion Cells and the Optic Disc
Figure 15.10b
Retinal Photoreceptors
• Rods:
– Respond to dim light
– Are used for peripheral vision
• Cones:
– Respond to bright light
– Have high-acuity color vision
– Are found in the macula lutea
– Are concentrated in the fovea centralis
Blood Supply to the Retina
• The neural retina receives its blood
supply from two sources
– The outer third receives its blood from the
choroid
– The inner two-thirds is by the central artery and
vein
Inner Chambers and Fluids
• The lens separates the internal eye into anterior
and posterior segments
• The posterior segment is filled with a clear gel
called vitreous humor that:
– Transmits light
– Supports the posterior surface of the lens
– Holds the neural retina firmly against the pigmented
layer
– Contributes to intraocular pressure
Anterior Segment
• Composed of two chambers
– Anterior – between the cornea and the iris
– Posterior – between the iris and the lens
• Aqueous humor
– A plasma like fluid that fills the anterior segment
– Drains via the canal of Schlemm
• Supports, nourishes, and removes wastes
Anterior Segment
Figure 15.12
Refraction and Lenses
• When light passes from one transparent
medium to another its speed changes and it
refracts (bends)
• Light passing through a convex lens (as in
the eye) is bent so that the rays converge to
a focal point
• When a convex lens forms an image, the
image is upside down and reversed right to
left
Refraction and Lenses
• Photoreception – process by which the eye
detects light energy
• Rods and cones contain visual pigments
(photopigments)
– Arranged in a stack of disk-like infoldings of the
plasma membrane that change shape as they
absorb light
Photoreception:
Functional Anatomy of Photoreceptors
Photoreception:
Functional Anatomy of Photoreceptors
Rods
• Functional characteristics
– Sensitive to dim light and best suited for night vision
– Absorb all wavelengths of visible light
– Perceived input is in gray tones only
– Sum of visual input from many rods feeds into a single
ganglion cell
– Results in fuzzy and indistinct images
Cones
• Functional
characteristics
– Need bright light for
activation (have low
sensitivity)
– Have pigments that
furnish a vividly colored
view
– Each cone synapses with
a single ganglion cell
– Vision is detailed and has
high resolution
The Ear: Hearing and Balance
• The three parts of the ear are the inner, outer,
and middle ear
• The outer and middle ear are involved with
hearing
• The inner ear functions in both hearing and
equilibrium
The Ear: Hearing and Balance
Figure 15.25a
Outer Ear
Auricle or Pinna
ear composed of elastic cartilage & skin to direct sound
waves to external auditory canal
External auditory meatus
Short curved tube from auricle to eardrum
Lined with skin, sebaceous glands, & ceruminous
glands (secrete earwax)
Tympanic membrane ( ear drum ) boundary
between outer & middle ear
Middle Ear (Tympanic Cavity)
• A small, air-filled, mucosa-lined cavity
– Flanked laterally by the eardrum
– Flanked medially by the oval and round windows
• Epitympanic recess – superior portion of the
middle ear
• Pharyngotympanic tube – connects the middle ear
to the nasopharynx
– Equalizes pressure in the middle ear cavity with the
external air pressure
Ear Ossicles
• The tympanic cavity contains three small
bones: the malleus, incus, and stapes
– Transmit vibratory motion of the eardrum to the
oval window
– Dampened by the tensor tympani and stapedius
muscles
Inner Ear
• Bony labyrinth
– Tortuous channels worming their way through the
temporal bone
– Contains the vestibule, the cochlea, and the semicircular
canals
– Filled with perilymph
• Membranous labyrinth
– Series of membranous sacs within the bony labyrinth
– Filled with a potassium-rich fluid
Inner Ear
The Cochlea
• The scala tympani terminates at the round
window
• The scalas tympani and vestibuli:
– Are filled with perilymph
– Are continuous with each other via the
helicotrema
• The scala media is filled with endolymph
The Cochlea
• The “floor” of the cochlear duct is composed
of:
– The bony spiral lamina
– The basilar membrane, which supports the
organ of Corti
• The cochlear branch of nerve VIII runs from
the organ of Corti to the brain
The Cochlea
Transmission of Sound to the Inner Ear
• The route of sound to the inner ear follows this
pathway:
– Outer ear – pinna, auditory canal, eardrum
– Middle ear – malleus, incus, and stapes to the oval
window
– Inner ear – scalas vestibuli and tympani to the cochlear
duct
• Stimulation of the organ of Corti
• Generation of impulses in the cochlear nerve
Transmission of Sound to the Inner Ear
Thank you

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special sense organs (anatomy and physiology) - a brief discussion

  • 1. Dr Pallab Kanti NathDr Pallab Kanti Nath MD AnaesthesiologyMD Anaesthesiology Basic level class for technicians
  • 2. Five Senses Vision (Sight) Smell (olfaction) Taste Touch Hearing Equilibrium is also considered a special sense, found in the ear
  • 4. Taste buds are found in papillae of the tongue mucosa Papillae - three types: filiform, fungiform, and circumvallate Fungiform and circumvallate papillae contain taste buds Appx 10,000 taste buds - each taste bud has 40-100 epithelial cells made of 3 major types:  Supporting Cells: separate and insulate  Receptor Cells: deal with taste  Basal cells: like stem cells, they give rise to new cells Taste Buds
  • 5. Taste Sensation • There are five basic taste sensations – Sweet – sugars, saccharin, alcohol, and some amino acids – Salt – metal ions – Sour – hydrogen ions – Bitter – alkaloids such as quinine and nicotine – Umami – elicited by the amino acid glutamate
  • 6. Activation  To be tasted, first must be dissolved in saliva, diffuse into the pore and make contact with gustatory hairs which trigger neurotransmitters to elicit action potentials in these fibers.  Adapt rapidly 3-5 seconds & completely in 1-5 minutes Taste Transduction  Process in which stimulus energy is converted into a nerve impulse due to influx of different ions Physiology of Taste
  • 7. Taste is carried by two cranial nerves  Facial: anterior 2/3rds of tongue  Glossopharyngeal: posterior 1/3rd  Taste triggers reflexes in digestion such as increasing saliva & gastric juice Gustatory Pathway Influence of other sensations on taste •Taste is 80% smell, when olfactory receptors are blocked food becomes bland •Thermoreceptors, mechanoreceptors, nociceptors, temperature and texture can enhance or detract
  • 8. Sense of Smell (Olfaction) • The organ of smell is the olfactory epithelium, which covers the superior nasal concha • Olfactory receptor cells are bipolar neurons with radiating olfactory cilia • Olfactory receptors are surrounded and cushioned by supporting cells • Basal cells lie at the base of the epithelium
  • 9.
  • 10. Olfactory epithelium Detects chemicals in solution Covered by mucous to trap airborne molecules Physiology Substance must be in a gaseous state Must be water soluble to dissolve in olfactory epithelium Bind to protein receptors which open ion channels that send action potentials to olfactory bulb Pathway Send impulses from bulb down tract Thalmus  Frontal Lobe or Hypothalmus to interpret and elicit emotional responses to odor Imablances include anosmia (without smells) from head injuries; unicinate fits (olfactory hallucinations) Olfaction
  • 11. Vision Accessory Structures Eyebrows Shade the eyes Prevent perspiration into eye Eyelids Palpabrae protects eye Levator palpebrae superioris raises eyelid Eyelashes trigger blinking Conjunctiva Mucous membrane over eyelids and anterior surface of eyeball (white part) Vascular, when irritated eyes are blood shot
  • 12.
  • 13. Extraocular muscles  Movement is controlled by 6 muscles  Four Rectus muscles: Superior, Inferior, Lateral, Medial  Two Oblique muscles: Superior, Inferior  Nerve Innervation: abducens, trochlear, oculomotor Lens : Divides eye into anterior and posterior segments  Transparent, flexible structure that can change shape to allow focus of light on retina  Avascular  Becomes less elastic through life causing focus impairment  Cataract – cloudy lens due to thickening of lens or diabetes
  • 15. Lacrimal Apparatus • Consists of the lacrimal gland and associated ducts • Lacrimal glands secrete tears • Tears – Contain mucus, antibodies, and lysozyme – Enter the eye via superolateral excretory ducts – Exit the eye medially via the lacrimal punctum – Drain into the nasolacrimal duct
  • 17. Structure of the Eyeball
  • 18. Fibrous Tunic • Forms the outermost coat of the eye and is composed of: – Opaque sclera (posteriorly) – Clear cornea (anteriorly) • The sclera protects the eye and anchors extrinsic muscles • The cornea lets light enter the eye
  • 19. Vascular Tunic (Uvea) • Has three regions: choroid, ciliary body, and iris • Choroid region –A dark brown membrane that forms the posterior portion of the uvea –Supplies blood to all eye tunics
  • 20. Vascular Tunic • A thickened ring of tissue surrounding the lens • Composed of smooth muscle bundles (ciliary muscles) • Anchors the suspensory ligament that holds the lens in place Ciliary Body
  • 21. • The colored part of the eye • Pupil – central opening of the iris – Regulates the amount of light entering the eye during: • Close vision and bright light – pupils constrict • Distant vision and dim light – pupils dilate • Changes in emotional state – pupils dilate when the subject matter is appealing or requires problem-solving skills Iris
  • 22. Pupil Dilation and Constriction
  • 23. Sensory Tunic: Retina • A delicate two-layered membrane • Pigmented layer – the outer layer that absorbs light and prevents its scattering • Neural layer, which contains: – Photoreceptors that transduce light energy – Bipolar cells and ganglion cells – Amacrine and horizontal cells
  • 25. The Retina: Ganglion Cells and the Optic Disc • Ganglion cell axons: – Run along the inner surface of the retina – Leave the eye as the optic nerve • The optic disc: – Is the site where the optic nerve leaves the eye – Lacks photoreceptors (the blind spot)
  • 26. The Retina: Ganglion Cells and the Optic Disc Figure 15.10b
  • 27. Retinal Photoreceptors • Rods: – Respond to dim light – Are used for peripheral vision • Cones: – Respond to bright light – Have high-acuity color vision – Are found in the macula lutea – Are concentrated in the fovea centralis
  • 28. Blood Supply to the Retina • The neural retina receives its blood supply from two sources – The outer third receives its blood from the choroid – The inner two-thirds is by the central artery and vein
  • 29. Inner Chambers and Fluids • The lens separates the internal eye into anterior and posterior segments • The posterior segment is filled with a clear gel called vitreous humor that: – Transmits light – Supports the posterior surface of the lens – Holds the neural retina firmly against the pigmented layer – Contributes to intraocular pressure
  • 30. Anterior Segment • Composed of two chambers – Anterior – between the cornea and the iris – Posterior – between the iris and the lens • Aqueous humor – A plasma like fluid that fills the anterior segment – Drains via the canal of Schlemm • Supports, nourishes, and removes wastes
  • 32. Refraction and Lenses • When light passes from one transparent medium to another its speed changes and it refracts (bends) • Light passing through a convex lens (as in the eye) is bent so that the rays converge to a focal point • When a convex lens forms an image, the image is upside down and reversed right to left
  • 34. • Photoreception – process by which the eye detects light energy • Rods and cones contain visual pigments (photopigments) – Arranged in a stack of disk-like infoldings of the plasma membrane that change shape as they absorb light Photoreception: Functional Anatomy of Photoreceptors
  • 36. Rods • Functional characteristics – Sensitive to dim light and best suited for night vision – Absorb all wavelengths of visible light – Perceived input is in gray tones only – Sum of visual input from many rods feeds into a single ganglion cell – Results in fuzzy and indistinct images
  • 37. Cones • Functional characteristics – Need bright light for activation (have low sensitivity) – Have pigments that furnish a vividly colored view – Each cone synapses with a single ganglion cell – Vision is detailed and has high resolution
  • 38. The Ear: Hearing and Balance • The three parts of the ear are the inner, outer, and middle ear • The outer and middle ear are involved with hearing • The inner ear functions in both hearing and equilibrium
  • 39. The Ear: Hearing and Balance Figure 15.25a
  • 40. Outer Ear Auricle or Pinna ear composed of elastic cartilage & skin to direct sound waves to external auditory canal External auditory meatus Short curved tube from auricle to eardrum Lined with skin, sebaceous glands, & ceruminous glands (secrete earwax) Tympanic membrane ( ear drum ) boundary between outer & middle ear
  • 41. Middle Ear (Tympanic Cavity) • A small, air-filled, mucosa-lined cavity – Flanked laterally by the eardrum – Flanked medially by the oval and round windows • Epitympanic recess – superior portion of the middle ear • Pharyngotympanic tube – connects the middle ear to the nasopharynx – Equalizes pressure in the middle ear cavity with the external air pressure
  • 42. Ear Ossicles • The tympanic cavity contains three small bones: the malleus, incus, and stapes – Transmit vibratory motion of the eardrum to the oval window – Dampened by the tensor tympani and stapedius muscles
  • 43. Inner Ear • Bony labyrinth – Tortuous channels worming their way through the temporal bone – Contains the vestibule, the cochlea, and the semicircular canals – Filled with perilymph • Membranous labyrinth – Series of membranous sacs within the bony labyrinth – Filled with a potassium-rich fluid
  • 45. The Cochlea • The scala tympani terminates at the round window • The scalas tympani and vestibuli: – Are filled with perilymph – Are continuous with each other via the helicotrema • The scala media is filled with endolymph
  • 46. The Cochlea • The “floor” of the cochlear duct is composed of: – The bony spiral lamina – The basilar membrane, which supports the organ of Corti • The cochlear branch of nerve VIII runs from the organ of Corti to the brain
  • 48. Transmission of Sound to the Inner Ear • The route of sound to the inner ear follows this pathway: – Outer ear – pinna, auditory canal, eardrum – Middle ear – malleus, incus, and stapes to the oval window – Inner ear – scalas vestibuli and tympani to the cochlear duct • Stimulation of the organ of Corti • Generation of impulses in the cochlear nerve
  • 49. Transmission of Sound to the Inner Ear