Koonal's slides from a short presentation (vignette) he gave at HTAi Annual Meeting 2018 summarising two study being undertaken in parallel to value health in children and adolescents. The audience comprised attendees at a conference focused on HTA.
Developing a value set for the EQ-5D-Y to support its use in HTA
1. Koonal Shah – Developing a value set for the EQ-5D-Y to support its use in HTA
HTAi Annual Meeting, Vancouver – 4 June 2018, 14:30-15:15
For more information, contact kshah@ohe.org
• No value sets exist to support use of the EQ-5D-Y in HTA
• Challenges in valuing EQ-5D-Y: normative, perspective, methodological
• Data collected can provide basis for an EQ-5D-Y value set for the UK
Study 1: Latent scale DCE study Study 2: Anchoring study
Discrete choice experiment – obtains EQ-5D-Y
values on a latent scale
Internet survey
Adult respondents (n=1000) asked to choose
between EQ-5D-Y states, considering the
health of a 10 year old child
Adolescent respondents (n=1005) completed
same survey, considering their own health
Modelling produced consistent coefficients
Sig. differences in preferences between
samples, but pain/discomfort and anxiety/
depression were most important for both
Study suggests that adolescents are capable
of completing a DCE (without death/duration)
Comparison of four methods for anchoring
latent scale values at 0 = dead
Computer-assisted personal interviews
VAS, TTO, DCE with duration, PUF
Adult respondents (n=299) asked to value EQ-
5D-Y states considering the health of a 10
year old child and EQ-5D-3L states
considering their own health
Broad agreement across all methods: values
were higher (and the anchor points were
lower) under the child health perspective
Results can be used to rescale the latent scale
values from study 1 so that they are anchored
at 0 (dead) and 1 (full health)