This third webinar in the series of Adverse Outcome Pathways (AOPs) was organised on Thursday 30 January 2020. It focused on the core information and telecommunication technologies applications that were built to support AOP development, management and dissemination. Tools and technical tips to facilitate scientific knowledge assembling and evaluations were also presented. The AOP framework implements a collaborative and innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment. Nathalie Delrue from the OECD Environment Directorate will briefly introduce the presenters and scope of the webinar
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Introduction of the webinar on the Adverse Outcome Pathways Knowledge Base and AOP developing tips - Nathalie Delrue, OECD Environment Directorate
1. Webinar on Adverse Outcome Pathways:
AOP Knowledge Base (AOP-KB) and AOP developing tips
Thursday 30 January 2020
@ 1 pm (CET, Paris time) / 7 am (EST)
2. • 1st webinar: Introduction to the AOP framework as a
collaborative tool – 30 April 2019
• 2nd webinar: Importance of weight of evidence in the process
of developing AOPs – 15 January 2020
• 3rd webinar: Today! 30 January 2020
– Applications of information and telecommunication technologies
built to support AOP development, management and dissemination.
– Tools and technical tips to facilitate scientific knowledge assembling
and evaluations
Scope of the AOP Webinar cycle
3. Presenters
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Clemens Wittwehr Dan Villeneuve Holly Mortensen
EC-JRC US EPA US EPA
Introduction onAOP-KB MakingAOP-KB entries easy
(technical tips)
Ways toretrieve information
from databases
and otherAOPtools
4. • Please send them any time during the webinar via the
chat box to Nathalie Delrue or to All
Any question?
6. • There is a great interest for AOPs; and tools are being
developed (as presented) to explore AOPs further
• The AOP KB will soon undergo an extensive revision;
AOP users are being consulted
• We are in the process of capturing specification
requirements and developing new features for the AOP
KB, and potential integration of these new tools
• Your feed back is welcome!
Concluding remarks:
7. Missed our previous webinars?
Watch the video recordings
AOP Knowledge Base (AOP-KB) and
AOP developing tips
The AOP framework as a
collaborative tool
Assembling and evaluating weight of
evidence (WoE) and quantitative
understanding
https://www.oecd.org/chemicalsafety/testing/webinars-on-
testing-and-assessment-methodologies.htm
9. • Adverse Outcome Pathways
http://www.oecd.org/chemicalsafety/testing/adverse-outcome-
pathways-molecular-screening-and-toxicogenomics.htm
• Future webinar announcements / Recordings of past webinars:
– Webinar Series on Testing and Assessment Methodologies
http://www.oecd.org/chemicalsafety/testing/webinars-on-testing-and-
assessment-methodologies.htm
– Webinar Series on Emerging Science to Improve Chemical Safety
http://www.oecd.org/chemicalsafety/testing/webinars-on-emerging-
science.htm
• Online training material
https://learning.aopkb.org/
Useful links - OECD website
10. Magdalini.Sachana@oecd.org
Nathalie.Delrue@oecd.org
2, rue André Pascal -
75775 Paris Cedex 16,
France
http://www.oecd.org/chemicalsafety/
Thanks For Watching
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