2. wounds whose depth exceeds the diameter of the visible
surface injury
Involve plantar surface of foot
Cause :
High-pressure injection equipment
Animal bites
Involving exposure to body fluids
3. PATHOPHYSIOLOGY
shear forces between the penetrating object and
tissue
result in tissue disruption, producing
hemorrhage and devitalization of skin and
underlying tissues
Inoculation of organisms into deeper tissues
Closure of wound favors infection
4. Infection rate from plantar puncture wound- 6 to 11 %
Gram positive organisms- Staphylococcus aureus,
streptococcus
• penetrate the joint capsule and produce septic arthritis,
• penetration of cartilage, periosteum, and bone can lead to
osteomyelitis
Pseudomonas aeruginosa isolated from plantar
puncture wound
6. Size and location of the wound
Condition of surrounding skin
Presence of foreign matter or devitalized tissue.
Proximity to underlying structures.
Distal function of tendons and nerves
Integrity of distal perfusion
CLINICAL FEATURES
8. Plain radiographs will detect
>90% of radiopaque foreign
bodies >1.0 mm in diameter
Organic substances, such as wood,
thorns, other plant matter, have
radiodensities close to that of soft
tissue and cannot reliably be
detected
9. USG can identify soft tissue foreign bodies, but the
ability to detect small objects is limited
CT or MRI : patients with deep-space infection,
persistent pain after a puncture wound, or treatment
failure
10. TREATMENT
Aggressive wound debridement and irrigation (no
evidence of reduction in rate or severity of post puncture
wound infections.)
Uncomplicated clean punctures <6 hrs : superficial wound
cleansing and tetanus prophylaxis
Low-pressure (e.g., approximately 0.5 psi) irrigation of
wounds : surface cleansing and allow visualization of the
entrance site.
11. Prophylactic antibiotics in High risk cases :
impaired host defenses, forefoot injuries and patients
sustaining punctures through athletic shoes
first-generation oral cephalosporin, antistaphylococcal
penicillin, or macrolide.
12. COMPLICATIONS
Pain >48 hours post injury should undergo an evaluation
for retained foreign body or infection
CELLULULITIS
• streptococcal and staphylococcal skin flora,
• 7- to 10-day course of a first-generation
cephalosporin, antistaphylococcal penicillin,
trimethoprim-sulfamethoxazole, or clindamycin
ABSCESS
• Standard incision and drainage.
• A short course of antibiotics is indicated if there is
surrounding cellulitis.
13. DEEP SOFT
TISSUE
INFECTION
• Parenteral antibiotics and surgical exploration with drainage of pus,
excision of necrotic tissue, and irrigation of infected areas
OSTEOMYELITIS
• Diagnosis : triple-phase radionuclide bone scan
• will demonstrate osteomyelitis within 72 hours of the onset of symptoms.
• Antibiotic administration after cultures
SKIN TATTOOING
14. Needle stick injury
major concerns are the risk of infection with the hepatitis
viruses and the human immunodeficiency virus (HIV).
Negligible for hepatitis A, 6% for hepatitis B, 2% for
hepatitis C, and 0.3% for HIV
Postexposure prophylaxis is available for hepatitis B and
HIV
15. High-pressure injection injuries
Caused by industrial equipment
designed to force grease, paint, or other
liquids through a small-diameter nozzle
at high pressures.
Extreme pressure can lacerate skin and
fracture bones
Type, amount, and viscosity of material
injected will determine the degree of
tissue inflammatory response
Can produce vascular injuries, ischemic
necrosis, and gangrene
16. Assessment of neurovascular integrity and tendon function
Aggressive pain management using IV opioids
Prophylactic antibiotic coverage against skin flora
Tetanus prophylaxis as indicated
Digital nerve blocks should be avoided, as they may further
increase pressure in finger compartments
Risk of subsequent amputation is reduced if wide surgical
debridement is performed within 6 hours of the injury
17. Epinephrine autoinjector
Patients present with pain due to the needle stick paresthesias, and
epinephrine-induced vasospasm to the injected area.
In the extreme, the entire digit can be blanched and cold.
spontaneous resolution, over 6 to 13 hours
18. subcutaneous phentolamine injection into the affected area
reverses digital ischemia
A mixture of 0.5 mL of standard phentolamine solution (5
milligrams/mL concentration) and 0.5 mL of 1% lidocaine
solution will produce a 1 mL total volume containing 2.5
milligrams of phentolamine that can be subcutaneously injected
directly through the site of autoinjector puncture.
19. MAMMALIAN BITES
GENERAL PRINCIPLES : Prevention or treatment of
local bacterial infection, and prevention, recognition, and
management of subsequent systemic illness.
Aggressive irrigation and debridement of devitalized
tissue
Determine the extent of underlying tissue damage, with
special attention to the potential for penetration into joint
spaces and tendon sheaths.
21. MICROBIOLOGY AND THERAPY OF INFECTIONS
FROM CAT AND DOG BITES
Bacterial proliferation in tissue can lead to serious
cellulitis, tenosynovitis, and septic arthritis
5% of untreated dog bites will become infected
80% of cat bites will become infected
Infection after a cat bite is often due to Pasteurella
multocida, particularly if the infection has a rapid onset
22. Bite Wounds at High Risk of Infection
5- to 7-day course of an appropriate antimicrobial
Amoxicillin-clavulanate is the medication most commonly recommended
penicillin V or ampicillin should be adequate for Pasteurella multocida infections
24. SYSTEMIC BACTERIAL INFECTIONS
AFTER DOG AND CAT BITES
Capnocytophaga canimorsus produces a rare but fulminant
bacteremic illness after a dog bite.
Fatal multi-organ failure in splenectomized patients or
alcoholic or with other immunosuppressive disorders.
Diagnosis is confirmed with positive blood cultures.
Broad-spectrum therapy with penicillin and other agents is
indicated in concert with aggressive resuscitation
25. Cat-scratch disease
clinical syndrome of regional lymphadenopathy, caused by
Bartonella henselae
7 to 12 days after a cat bite or scratch.
painful, matted masses of lymph nodes. low-grade fever, malaise,
fatigue, headache, nausea, and anorexia.
CNS (encephalopathy with headache, seizures, confusion, or AMS )
Musculoskeletal (synovitis with joint pain and swelling)
Lungs (pneumonitis with dyspnea and cough)
Abdomen (granulomatous hepatitis or splenitis producing abdominal
pain)
Eyes (retinitis with vision loss), and often with a prolonged fever.
26. Management
Diagnosis- epidemiologic, clinical, histologic, and/or serologic
criteria
Resolve in 2 to 5 months, and therapy is primarily pain relief and
reassurance.
Large, painful, fluctuant nodes can be aspirated for symptomatic
relief.
Patients with severe painful lymphadenopathy, a 5-day course of
azithromycin may speed resolution of adenopathy
Immunodeficiencies- 7 to 10-day course of trimethoprim-
sulfamethoxazole, ciprofloxacin, or rifampin.
27. Human bites
More serious than bites from domestic animals due to the
nature of the event, location of the bite, and potential
bacteria inoculated into the wound.
staphylococcal and streptococcal species, gram-negative
rod Eikenella corrodens
Amoxicillin-clavulanate is recommended for treatment
and prophylaxis
28. Herpes simplex virus
infection
herpetic whitlow is a painful coalescence of vesicles,
typically on the distal phalanx
Vesicles usually resolve in 3 to 4 weeks.
Treatment with oral acyclovir for 7 to 10 days or topical
acyclovir ointment for 7 to 14 days may shorten the
duration of the symptoms
29. RODENTS, LIVESTOCK, EXOTIC AND WILD
ANIMALS
Rat-bite fever consists of two similar febrile illnesses - either
Streptobacillus moniliformis (more common in North America) or Spirillum
minus/minor (more common in Asia).
Incubation period 3 to 7 days.
Rigors and fever that progresses to migratory polyarthralgia and a
maculopapular petechial or purpuric rash.
Infection can spread to the heart, brain, arteries, liver, kidneys, and lungs.
Mortality rate -10% to 15%.
Treatment is penicillin, or for penicillin-allergic patients, doxycycline or
tetracycline.
30. Livestock and large game animals can inflict serious tissue
injury with their powerful jaws and grinding teeth.
systemic illnesses, such as brucellosis, leptospirosis, or
tularemia.
Aggressive wound care, imaging to detect fracture, and
prophylactic broad-spectrum antibiotics are recommended.
Antibiotic therapy guided by blood culture results.
31. Freshwater fish bites can harbor Aeromonas, streptococci,
and staphylococci
Treatment includes a fluoroquinolone or
trimethoprimsulfamethoxazole.
Saltwater fish bites require coverage for Vibrio, usually
with a fluoroquinolone.
32. SYSTEMIC INFECTIONS: SPIROCHETES,
RABIES, AND OTHER VIRUSES
Disseminated spirochetal and viral illnesses that can result
from mammalian bites include syphilis, rabies, hepatitis,
herpes B virus, or HIV.
In South Asia, monkeys are presumed to be at high risk
for carriage and transmission of rabies.
North American reservoirs of animal rabies exist in bats,
skunks, raccoons, and foxes
33. .
Herpes B virus, also called Cercopithecine herpesvirus 1,
can be transmitted by bites from monkeys and other
nonhuman primates.
In humans, infection with herpes B causes myelitis and
hemorrhagic encephalitis with a case fatality rate of 70%.
Immediate and thorough wound cleaning after a bite
reduces the chance of infection, and acyclovir or
valacyclovir given immediately after injury can prevent or
ameliorate this illness.
Editor's Notes
potential zoonotic systemic infections carried by mice and rats