This document summarizes key findings and lessons from research on psoriasis that can help inform the understanding of alopecia areata. It outlines the main cells and mediators involved in the pathogenesis of psoriasis such as Th1, Th17, and Th22 cells. It also summarizes clinical trials that demonstrated the efficacy of biologics targeting cytokines such as TNF-α, IL-12/IL-23, IL-17, and IL-23 for treating psoriasis. The document aims to draw parallels between the pathogenesis of psoriasis and alopecia areata to help identify new potential treatment targets and strategies for alopecia areata.
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Lessons from Psoriasis: What Can We Apply to Alopecia Areata?
1. Lessons from Psoriasis-What Can
We Apply to Alopecia Areata?
Mark Lebwohl, MD
ProfessorAnd Chairman
Kimberly and Eric J. Waldman
Department of Dermatology
Icahn School of Medicine at Mount Sinai
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