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- 19. Conclusion 140 - 270 90 - 360 4 hours – 8 hours 120 - 240 45 - 90 Duration (with Epinephrine) in minutes 4.0mg/kg – 7mg/kg Rapid 7.8 Articaine 5mg/kg – 7.5mg/kg Medium 7.9 Prilocaine 2.5mg/kg – 3mg/kg Slow 8.1 Bupivacaine 4.5mg/kg – 7mg/kg Rapid 7.9 Lidocaine 8mg/kg – 10mg/kg Slow 9.1 Procaine Max Dose (with Epinephrine) Onset pKa Anesthetic