Pph drill

L
Lifecare CentreDirector um Dr. Sharda jain
Dr. Monika Madaan
Specialist
Dept. Of Obstetrics & Gynaecology
ESI Hospital
Manesar
PPH
Single most important cause of maternal

mortality worldwide.
Accounts for 34% of maternal deaths in
developing countries.
Definition
Any blood loss than has potential to

produce or produces hemodynamic
instability
Definition
Blood loss > 500 ml after delivery
Primary : Loss within 1st 24 hours after

delivery
Secondary : 24 hours till 12 weeks postnatally
Minor : 500-1000 ml
Moderate : 1000-2000 ml
Severe : > 2000 ml
PREDICTION AND PREVENTION
- Pl previa/accreta
- Anticoagulation Rx
- Coagulopathy
- Overdistended uterus

Identify pt. at risk

- Grand multiparity
- Abn labor pattern
- Chorioamnionitis
- Large myomas
- Previous history of PPH
PREDICTION AND PREVENTION
Active Management Of Third Stage Of Labor
(AMTSL): Should be offered routinely and
includes:
1.Administration of uterotonics soon after birth.
2.Delayed cord clamping.
3.Delivery of placenta by controlled cord
traction followed by uterine massage.
PPH Drill
Clear and logical sequence of steps

essential in the management of PPH.
CALL
FOR
HELP
Team Effort
•Skilled Obstetric Team
•Trained

Anaesthesiologist
•Clinical hematologist
•Supporting staff
Resuscitation
Assess
A : Airway
B : Breathing
C : Circulation
 Secure 2 wide bore i.v. lines:- 14-16 gauge
 Draw blood for grouping & cross matching,

CBC, LFT/KFT, SE & Coagulogram.
Position flat
Keep the patient warm
Administer oxygen by mask ( @ 10-15 litres/

min)
Catheterize the patient for emptying bladder &
monitoring output
Fluid Replacement
RAPID WARMED infusion of fluids
Crystalloids : Fluids of choice until

compatible blood is arranged
1 ml of blood loss= 3 ml of crystalloids
Total volume of 3.5 litres of clear fluids
(upto 2 litres of crystalloids followed by 1.5
litres of warmed colloid )may be given while
awaiting compatible blood.
If hemorrhage is torrential
& fully cross-matched
blood still not available :
Uncrossmatched O
negative blood may be
given
FFP: 4 Units for every 6 Units of red cells OR

PT/ APTT > 1.5 X normal
(ie 12-15 ml/kg or total of 1 litres.)
Platelet Concentrate: if Platelet count< 50,000/
microlitre.
Cryoprecipitate: if fibrinogen < 1 g/ l.
Continuous vital monitoring.
Monitor adequacy of replacement with urine

output (0.5 ml/kg/hr) and CVP (4-8 cm water)
Main therapeutic goals are to maintain:
Haemoglobin > 8gm/dl
Platelet count > 75 × 109 / l
Prothrombin < 1.5 × mean control
APTT < 1.5 × mean control
Fibrinogen > 1 gm/ l
Establish Etiology Simultaneously
4 T’s
Tone (abnormalities of uterine contraction) :

70 – 80%
Trauma (of the genital tract) : 20 %
Tissue (retained products of conception) : 10
%
Thrombin (abnormalities of coagulation) : 1 %
Contd…
Bimanual
Compression
If uterus is
relaxed :
massaging the
uterus will expel
any retained bits &
stimulate uterine
contractions
Administer Uterotonic Drugs
FIRST LINE

Oxytocin:
Start with 5 units slow iv or im.
Infusion of 20 units in 1 L@ 60 dr/min.
Continue same dose @ 40 dr/min until bleeding stops.
Maximum upto 3 L.
SECOND LINE
Ergometrine/ methyl ergometrine:
Dose: 0.2 mg im or slow iv
Repeat 0.2 mg after 15 min.
Maximum 5 doses (1 mg)
Syntometrine im
THIRD LINE

PGF 2α:
Dose: 0.25 mg im.
Can be repeated every 15 min.
Maximum upto 2 mg or 8 doses.
Misoprostol:
200-800 µg sublingually.
Do not exceed 800 µg
WHO GUIDELINES FOR MANAGEMENT OF PPH 2009
Uterine Tamponade
• Bakri

balloon
• Sengstaken Blakemore
oesophageal catheter
• Condom catheter
• Urological Rusch
balloon
Success depends upon
Positive Tamponade test
insertion
Initial Assembly
 Condoms-2
 Foley’s catheter-no.16
 Saline with iv set
 Speculum
 Sponge holding

forceps
Procedure
Lithotomy position
Indwelling Foley’s

catheter.
Explore uterus, cervix and
vagina.
Inflate balloon with 100300 ml warm 0.9% Sodium
chloride until bleeding is
controlled (Positive
Tamponade Test).
Compression sutures
B Lynch Suture
•Fundal
compression suture
•Apposes anterior
& posterior wall
Contd…

Parallel Vertical compression sutures for placenta
praevia
Stepwise Uterine Devascularization
•Uterine arteries
•Tubal branch of ovarian

artery
•Internal iliac artery
Uterine Artery Embolization
Possible only if internal
artery ligation has not
been done and facility
for interventional
radiology available
Hysterectomy
Resort to hysterectomy “SOONER RATHER

THAN LATER”
High maternal morbidity
Timing and adequate replacement is of utmost
importance
Documentation and Debriefing
Important to record:
Sequence of events
Time and sequence of admn of
pharmacological agents, fluids, blood products
The time of surgical intervention
The condition of mother throughout .
Newer Developments
Tranexamic acid : 1 gm i.v slow. Can be

repeated after 30 min if bleeding continues./
Recombinant activated factor VII
(Novoseven): 90 µg/ kg . May be repeated
within 15-30 minutes. No clear consensus on
efficacy.
Carbetocin (oxytocin agonist) : 100 µg i.v or
i.m. Produces tetanic uterine contractions.
HAEMOSTASIS ALGORITHM
H – Ask for help
A – Assess and resuscitate
E – Establish etiology
M – Massage the uterus
O – Oxytocic administration
S – Shift to OT
T – Tissue n trauma to be excluded and proceed to
tamponade
A – Apply compression sutures
S – Systematic pelvic devascularisation
I – Interventional radiology
S – Subtotal or total hysterectomy
To Conclude, Management of
PPH Has Evolved From:
Panic
Panic
Hysterectomy
 Pitocin
 Prostaglandins
 Happiness
&
ADDRESS
35 , Defence Enclave, Opp. Preet Vihar Petrol
Pump, Metro pillar no. 88, Vikas Marg , Delhi –
110092
CONTACT US
011-22414049, 42401339
WEBSITE :
www.lifecarecentre.in
www.drshardajain.com
www.lifecareivf.com
E-MAIL ID
Sharda.lifecare@gmail.com
Lifecarecentre21@gmail.com
info@lifecareivf.com
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GAS CHROMATOGRAPHY-Principle, Instrumentation Advantage and disadvantage appl... von DipeshGamare
GAS CHROMATOGRAPHY-Principle, Instrumentation Advantage and disadvantage appl...GAS CHROMATOGRAPHY-Principle, Instrumentation Advantage and disadvantage appl...
GAS CHROMATOGRAPHY-Principle, Instrumentation Advantage and disadvantage appl...
DipeshGamare18 views

Pph drill

  • 1. Dr. Monika Madaan Specialist Dept. Of Obstetrics & Gynaecology ESI Hospital Manesar
  • 2. PPH Single most important cause of maternal mortality worldwide. Accounts for 34% of maternal deaths in developing countries.
  • 3. Definition Any blood loss than has potential to produce or produces hemodynamic instability
  • 4. Definition Blood loss > 500 ml after delivery Primary : Loss within 1st 24 hours after delivery Secondary : 24 hours till 12 weeks postnatally Minor : 500-1000 ml Moderate : 1000-2000 ml Severe : > 2000 ml
  • 5. PREDICTION AND PREVENTION - Pl previa/accreta - Anticoagulation Rx - Coagulopathy - Overdistended uterus Identify pt. at risk - Grand multiparity - Abn labor pattern - Chorioamnionitis - Large myomas - Previous history of PPH
  • 6. PREDICTION AND PREVENTION Active Management Of Third Stage Of Labor (AMTSL): Should be offered routinely and includes: 1.Administration of uterotonics soon after birth. 2.Delayed cord clamping. 3.Delivery of placenta by controlled cord traction followed by uterine massage.
  • 7. PPH Drill Clear and logical sequence of steps essential in the management of PPH.
  • 9. Team Effort •Skilled Obstetric Team •Trained Anaesthesiologist •Clinical hematologist •Supporting staff
  • 10. Resuscitation Assess A : Airway B : Breathing C : Circulation  Secure 2 wide bore i.v. lines:- 14-16 gauge  Draw blood for grouping & cross matching, CBC, LFT/KFT, SE & Coagulogram.
  • 11. Position flat Keep the patient warm Administer oxygen by mask ( @ 10-15 litres/ min) Catheterize the patient for emptying bladder & monitoring output
  • 12. Fluid Replacement RAPID WARMED infusion of fluids Crystalloids : Fluids of choice until compatible blood is arranged 1 ml of blood loss= 3 ml of crystalloids Total volume of 3.5 litres of clear fluids (upto 2 litres of crystalloids followed by 1.5 litres of warmed colloid )may be given while awaiting compatible blood.
  • 13. If hemorrhage is torrential & fully cross-matched blood still not available : Uncrossmatched O negative blood may be given
  • 14. FFP: 4 Units for every 6 Units of red cells OR PT/ APTT > 1.5 X normal (ie 12-15 ml/kg or total of 1 litres.) Platelet Concentrate: if Platelet count< 50,000/ microlitre. Cryoprecipitate: if fibrinogen < 1 g/ l.
  • 15. Continuous vital monitoring. Monitor adequacy of replacement with urine output (0.5 ml/kg/hr) and CVP (4-8 cm water) Main therapeutic goals are to maintain: Haemoglobin > 8gm/dl Platelet count > 75 × 109 / l Prothrombin < 1.5 × mean control APTT < 1.5 × mean control Fibrinogen > 1 gm/ l
  • 16. Establish Etiology Simultaneously 4 T’s Tone (abnormalities of uterine contraction) : 70 – 80% Trauma (of the genital tract) : 20 % Tissue (retained products of conception) : 10 % Thrombin (abnormalities of coagulation) : 1 %
  • 18. Bimanual Compression If uterus is relaxed : massaging the uterus will expel any retained bits & stimulate uterine contractions
  • 19. Administer Uterotonic Drugs FIRST LINE Oxytocin: Start with 5 units slow iv or im. Infusion of 20 units in 1 L@ 60 dr/min. Continue same dose @ 40 dr/min until bleeding stops. Maximum upto 3 L. SECOND LINE Ergometrine/ methyl ergometrine: Dose: 0.2 mg im or slow iv Repeat 0.2 mg after 15 min. Maximum 5 doses (1 mg) Syntometrine im
  • 20. THIRD LINE PGF 2α: Dose: 0.25 mg im. Can be repeated every 15 min. Maximum upto 2 mg or 8 doses. Misoprostol: 200-800 µg sublingually. Do not exceed 800 µg WHO GUIDELINES FOR MANAGEMENT OF PPH 2009
  • 21. Uterine Tamponade • Bakri balloon • Sengstaken Blakemore oesophageal catheter • Condom catheter • Urological Rusch balloon Success depends upon Positive Tamponade test
  • 22. insertion Initial Assembly  Condoms-2  Foley’s catheter-no.16  Saline with iv set  Speculum  Sponge holding forceps
  • 23. Procedure Lithotomy position Indwelling Foley’s catheter. Explore uterus, cervix and vagina. Inflate balloon with 100300 ml warm 0.9% Sodium chloride until bleeding is controlled (Positive Tamponade Test).
  • 24. Compression sutures B Lynch Suture •Fundal compression suture •Apposes anterior & posterior wall
  • 25. Contd… Parallel Vertical compression sutures for placenta praevia
  • 26. Stepwise Uterine Devascularization •Uterine arteries •Tubal branch of ovarian artery •Internal iliac artery
  • 27. Uterine Artery Embolization Possible only if internal artery ligation has not been done and facility for interventional radiology available
  • 28. Hysterectomy Resort to hysterectomy “SOONER RATHER THAN LATER” High maternal morbidity Timing and adequate replacement is of utmost importance
  • 29. Documentation and Debriefing Important to record: Sequence of events Time and sequence of admn of pharmacological agents, fluids, blood products The time of surgical intervention The condition of mother throughout .
  • 30. Newer Developments Tranexamic acid : 1 gm i.v slow. Can be repeated after 30 min if bleeding continues./ Recombinant activated factor VII (Novoseven): 90 µg/ kg . May be repeated within 15-30 minutes. No clear consensus on efficacy. Carbetocin (oxytocin agonist) : 100 µg i.v or i.m. Produces tetanic uterine contractions.
  • 31. HAEMOSTASIS ALGORITHM H – Ask for help A – Assess and resuscitate E – Establish etiology M – Massage the uterus O – Oxytocic administration S – Shift to OT T – Tissue n trauma to be excluded and proceed to tamponade A – Apply compression sutures S – Systematic pelvic devascularisation I – Interventional radiology S – Subtotal or total hysterectomy
  • 32. To Conclude, Management of PPH Has Evolved From: Panic Panic Hysterectomy  Pitocin  Prostaglandins  Happiness
  • 33. & ADDRESS 35 , Defence Enclave, Opp. Preet Vihar Petrol Pump, Metro pillar no. 88, Vikas Marg , Delhi – 110092 CONTACT US 011-22414049, 42401339 WEBSITE : www.lifecarecentre.in www.drshardajain.com www.lifecareivf.com E-MAIL ID Sharda.lifecare@gmail.com Lifecarecentre21@gmail.com info@lifecareivf.com