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The facts

11/20/13

FI
Female & Male Hormones
Female Sex Hormones
The ovaries secrete two hormones, oestrogen and
progesterone
Male Sex Hormones
 Testosterone & determines the primary and secondary sex

characteristics.
 The male reproductive system is controlled by hormones
from the hypothalamus and from the anterior pituitary
gland.

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FI
11/20/13

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Female Reproductive System

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Female Reproductive System

11/20/13

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Hormonal control of the female
reproductive cycle.
The two cycles are the ovarian cycle and the

uterine cycle. The cycles are interrelated and
average 28 days.

The ovarian cycle is divided into the follicular

phase and the luteal phase.

During the follicular phase the ovarian follicle

matures primarily in response to FSH. The
follicular phase ends with ovulation and is
dominated by oestrogen.

11/20/13

FI
The uterine cycle is divided into the menstral

phase, the proliferative phase and the secretory
phase.
Menstral – loss of part of the endometrial lining and

blood (menstruation)

Proliferative – endometrial lining thickens and becomes

vascular (primarily in response to oestrogen)

Secretory – endometrial lining becomes lush and moist

from increased secretory activity (primarily in response
to progesterone)

11/20/13

FI
Structure and Function of the
Breast

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Structure and Function of the
Breast

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Hormonal and
Menstrual Alterations
Polycystic ovarian syndrome
Leading cause of infertility in the United States
Oligo-ovulation or anovulation
Elevated levels of androgens or clinical signs of

hyperandrogenism and polycystic ovaries
Multifactorial


Hyperinsulinism, hypertension, dyslipidemia

Dysfunction of follicle development

11/20/13

FI
Infection and Inflammation
Pelvic inflammatory disease (PID)
Acute inflammatory disease caused by infection
May involve any organ of the reproductive tract

Salpingitis
 Oophoritis


Sexually transmitted diseases migrate from the

vagina to the upper genital tract
Polymicrobial infection

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Pelvic Inflammatory Disease (PID)

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FI
Pelvic Inflammatory Disease (PID)

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FI
Pelvic Relaxation Disorders
The bladder, urethra, and rectum are supported

by the endopelvic fascia and perineal muscles
The muscular and fascial tissue loses tone and
strength with aging
Fails to maintain organs in proper position

11/20/13

FI
Pelvic Relaxation Disorders
Cystocele and rectocele
Urethrocele
Cystourethrocele
Enterocele
Vaginal prolapse
Uterine prolapse

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FI
Pelvic Relaxation Disorders

11/20/13

FI
Benign Growths and
Proliferative Conditions
Endometriosis
Presence of functioning endometrial tissue or

implants outside the uterus
Responds to hormone fluctuations of the menstrual
cycle
Possible causes


11/20/13

Retrograde menstruation, spread through vascular or
lymphatic systems, stimulation of multipotential
epithelial cells on reproductive organs or genetic
predisposition
FI
Cervical Cancer

11/20/13

FI
Benign Growths and
Proliferative Conditions
Endometriosis

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FI
Breast Cancer
Reproductive factors
Hormonal factors
Environmental factors and lifestyle
Radiation
Diet
Chemicals (xenoestrogens)

Physical activity
Familial factors and tumor-related genes
11/20/13

FI
Breast Cancer
Manifestations
Painless lump, dimpling of skin, edema

Treatment
Based on stage of cancer
Surgery, radiation, chemotherapy, hormone

therapy, biologic therapy and bone marrow
transplantation

11/20/13

FI

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Reproductive system 2010

  • 2. Female & Male Hormones Female Sex Hormones The ovaries secrete two hormones, oestrogen and progesterone Male Sex Hormones  Testosterone & determines the primary and secondary sex characteristics.  The male reproductive system is controlled by hormones from the hypothalamus and from the anterior pituitary gland. 11/20/13 FI
  • 6. Hormonal control of the female reproductive cycle. The two cycles are the ovarian cycle and the uterine cycle. The cycles are interrelated and average 28 days. The ovarian cycle is divided into the follicular phase and the luteal phase. During the follicular phase the ovarian follicle matures primarily in response to FSH. The follicular phase ends with ovulation and is dominated by oestrogen. 11/20/13 FI
  • 7. The uterine cycle is divided into the menstral phase, the proliferative phase and the secretory phase. Menstral – loss of part of the endometrial lining and blood (menstruation) Proliferative – endometrial lining thickens and becomes vascular (primarily in response to oestrogen) Secretory – endometrial lining becomes lush and moist from increased secretory activity (primarily in response to progesterone) 11/20/13 FI
  • 8. Structure and Function of the Breast 11/20/13 FI
  • 9. Structure and Function of the Breast 11/20/13 FI
  • 11. Hormonal and Menstrual Alterations Polycystic ovarian syndrome Leading cause of infertility in the United States Oligo-ovulation or anovulation Elevated levels of androgens or clinical signs of hyperandrogenism and polycystic ovaries Multifactorial  Hyperinsulinism, hypertension, dyslipidemia Dysfunction of follicle development 11/20/13 FI
  • 12. Infection and Inflammation Pelvic inflammatory disease (PID) Acute inflammatory disease caused by infection May involve any organ of the reproductive tract Salpingitis  Oophoritis  Sexually transmitted diseases migrate from the vagina to the upper genital tract Polymicrobial infection 11/20/13 FI
  • 13. Pelvic Inflammatory Disease (PID) 11/20/13 FI
  • 14. Pelvic Inflammatory Disease (PID) 11/20/13 FI
  • 15. Pelvic Relaxation Disorders The bladder, urethra, and rectum are supported by the endopelvic fascia and perineal muscles The muscular and fascial tissue loses tone and strength with aging Fails to maintain organs in proper position 11/20/13 FI
  • 16. Pelvic Relaxation Disorders Cystocele and rectocele Urethrocele Cystourethrocele Enterocele Vaginal prolapse Uterine prolapse 11/20/13 FI
  • 18. Benign Growths and Proliferative Conditions Endometriosis Presence of functioning endometrial tissue or implants outside the uterus Responds to hormone fluctuations of the menstrual cycle Possible causes  11/20/13 Retrograde menstruation, spread through vascular or lymphatic systems, stimulation of multipotential epithelial cells on reproductive organs or genetic predisposition FI
  • 20. Benign Growths and Proliferative Conditions Endometriosis 11/20/13 FI
  • 21. Breast Cancer Reproductive factors Hormonal factors Environmental factors and lifestyle Radiation Diet Chemicals (xenoestrogens) Physical activity Familial factors and tumor-related genes 11/20/13 FI
  • 22. Breast Cancer Manifestations Painless lump, dimpling of skin, edema Treatment Based on stage of cancer Surgery, radiation, chemotherapy, hormone therapy, biologic therapy and bone marrow transplantation 11/20/13 FI