This document provides advice on pursuing an academic career in science. It begins with the author questioning whether such a career is still feasible given low success rates for fellowship and grant applications. The author then outlines their own academic career path from 1978-2005. They note that their own history is not relevant to current challenges. The document also lists former students and fellows, noting many have pursued careers outside of academia. It provides tips for improving chances of success, such as networking and customizing applications. Finally, it discusses traits of highly creative people and includes additional resource links.