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Coccinia grandis
&
Its pharmacological activities
Jatindra nath Mohanty, JRF
Belongs to family Cucurbitaceae.
Over 900 species in Coccinia genus.
A tropical and perennial crop.
Has both high nutritional and
medicinal values.
Leaves are alternate, heart to
pentagonal shape.
Dioecious in nature
Angiosperm bearing fruits in female
plants.
Coccinia grandis Voigt
Heart Shaped PentagonalTendrils
Leaves of C. grandis
Flowers
Female Flower
GyM –H Type
Male Flower
GyM –F Type
Red in color when ripe
Ovoid to elliptical
shape
25-60mm long,15-
35mm diameter
Glabrous, hairless stalk
Fruits
Succulent, tuberous
Desperation by
humans, birds, cattle,
pigs etc.
Germinates with
suitable conditions
Stem & Root
Part of plant Chemical constituents Medicinal value
Stem and leaf
Heptacosane, cephalandrol, β- sitosterole,
Alkaloids Cephalandrins A&B
Antidiabetic, oxidant, larvicadal, GI
disturbances, Cooling
effect to the eye, Gonorrhea,
hypolipidemic, skin diseases,
urinary tract infection Expectorant,
antispasmodic, asthma, bronchitis,
urinary tract infection.
Root
Resin, Alkaloids, Starch, Fatty Acids,
Carbonic acid,
Triterpenoid, Saponin Coccinoside,
Flavonoid Glycoside, Lupeol,
β-amyrin, β-sitosterol, Taraxerol
Hypoglycemic, antidiabetic, skin diseases,
removes pain in
joint, urinary tract infection
Fruit
β- Amyrin Acetate, Lupeol, Cucurbitacin B,
Taraxerone,
Taraxerol, β-carotene, Lycopene,
Cryptoxanthin, Xyloglucan,
Carotenoids, β-sitosterol, Stigma-7-en-3-
one.
Hypoglycemic, analgesic, antipyretic,
Hepatoprotective,
tuberculosis, eczema. anti-inflammatory.
Chemical constituents and medicinal value
Antibacterial
Anthelmintic
Antioxidant
Antiulcer
Antimalerials
Anti-inflammatory
Antipyretic
Analgesic
Antifungal
Anticancer
Antitussive
α - amylase inhibition
Hypoglycemic
Hepatoprotective
Pharmacological Applications
Conclusions
 Coccinia grandis holds a great nutritional and
economical importance.
 Several pharmacological applications make it
further precious and worthy of exploration.
 Being dioecious in nature it can act as a model
plant for study of sex linked genetic expressions.
 Showing so many morphological variation in sexes
like male, female, hermaphrodite,
gynomonoecious etc it may lead to the revelation
of the evolution of sexes in plants.
Pharmacological activities of coccinia grandis

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Pharmacological activities of coccinia grandis

  • 1. Coccinia grandis & Its pharmacological activities Jatindra nath Mohanty, JRF
  • 2. Belongs to family Cucurbitaceae. Over 900 species in Coccinia genus. A tropical and perennial crop. Has both high nutritional and medicinal values. Leaves are alternate, heart to pentagonal shape. Dioecious in nature Angiosperm bearing fruits in female plants. Coccinia grandis Voigt
  • 4. Flowers Female Flower GyM –H Type Male Flower GyM –F Type
  • 5. Red in color when ripe Ovoid to elliptical shape 25-60mm long,15- 35mm diameter Glabrous, hairless stalk Fruits Succulent, tuberous Desperation by humans, birds, cattle, pigs etc. Germinates with suitable conditions Stem & Root
  • 6. Part of plant Chemical constituents Medicinal value Stem and leaf Heptacosane, cephalandrol, β- sitosterole, Alkaloids Cephalandrins A&B Antidiabetic, oxidant, larvicadal, GI disturbances, Cooling effect to the eye, Gonorrhea, hypolipidemic, skin diseases, urinary tract infection Expectorant, antispasmodic, asthma, bronchitis, urinary tract infection. Root Resin, Alkaloids, Starch, Fatty Acids, Carbonic acid, Triterpenoid, Saponin Coccinoside, Flavonoid Glycoside, Lupeol, β-amyrin, β-sitosterol, Taraxerol Hypoglycemic, antidiabetic, skin diseases, removes pain in joint, urinary tract infection Fruit β- Amyrin Acetate, Lupeol, Cucurbitacin B, Taraxerone, Taraxerol, β-carotene, Lycopene, Cryptoxanthin, Xyloglucan, Carotenoids, β-sitosterol, Stigma-7-en-3- one. Hypoglycemic, analgesic, antipyretic, Hepatoprotective, tuberculosis, eczema. anti-inflammatory. Chemical constituents and medicinal value
  • 8. Conclusions  Coccinia grandis holds a great nutritional and economical importance.  Several pharmacological applications make it further precious and worthy of exploration.  Being dioecious in nature it can act as a model plant for study of sex linked genetic expressions.  Showing so many morphological variation in sexes like male, female, hermaphrodite, gynomonoecious etc it may lead to the revelation of the evolution of sexes in plants.