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One Health approaches
   to prevent and control zoonoses

                   Jeffrey Gilbert, ILRI
                   CIAT-Asia, Vientiane




Agriculture, Fisheries & Conservation Department (AFCD) Workshop on
                “One Health: Past, Present, and Future”
                       Hong Kong, 27 September 2011
ILRI: Overview

• One of 15 international research centers of CGIAR (Consultative
  Group on International Agricultural Research)
• Individual Centres set up in 1960s (IRRI 1960, ILRAD 1973, ILCA
  1974)
• CGIAR 1971: 19 northern Govts + IGO (FAO,WB,ADB …)
• ILRI founded 1994; headquarters in Nairobi, Kenya
• ILRI focus – livestock, livelihoods, IAR4D

• ILRI: organized in 4 research ‘themes’: markets, biotechnology,
  people-livestock-environment, poverty-gender-impact
ILRI: Resources




     IAR4D
CG Reform
 To overcome the challenges and exploit the opportunities, the CGIAR has
  undergone reform. A new Strategy and Results Framework (SRF) will, for
  the first time, allow the CGIAR centers to function as a unified system,
  working together to pursue shared goals
 The 7 CGIAR Research Programmes* (formerly ‘mega-programmes’)
 Objective – to harmonize
 CRP-4: ‘Agriculture for Improved Health and Nutrition’
• This research program aims to accelerate progress in improving the
  nutrition and health of poor people by exploiting and enhancing the
  synergies between agriculture, nutrition, and health through four key
  research components: value chains, biofortification, control of
  agriculture-associated diseases, and integrated agriculture, nutrition, and
  health development programs and policies. With IFPRI and ILRI as co-
  Lead Centers, this program will also involve 10 other CGIAR Centers. It
  has an initial 3-year budget of US$191.4 million.




* http://www.cgiarfund.org/cgiarfund/research_portfolio
EcoHealth v OneHealth

• Definitions open to debate: range from quite rigid to
  very flexible!
• One-Health – biomedical focus: human + animal +
  wildlife;
• EcoHealth: environment & socio-economic aspects –
  pioneered outside ‘traditional’ health
• Personal opinion: OneHealth more theoretical,
  conceptual; EcoHealth more tangible?
• Maybe it’s not so important … which ‘cola’
EcoHealth v OneHealth


• Option to discuss history of EH/OH
EcoHealth


                                             One world – one health
                                                 EcoHealth



                                                                  Human
                                               One                Animal
                                                                  health
                                  Human
                                               Medicine           health
                                  health
                                              Vet
                                             Pub
                                            O H. e
                                               n      h e a l t h



                                           Agroecosystem health



                                                 Societies
                                                 Economies
                                                 Institutions
Adapted from Esther Schelling, STPH
EcoHealth
EcoHealth ‘Pillars’
   Trans-disciplinary: inclusive vision, full involvement
    of Researchers, community & decision-makers;
   Participation: consensus and cooperation not only
    within community, scientific & decision-making
    groups, but among them;
   Equity: gender, ethnic group;
   Sustainability.
EcoHealth: transdisciplinarity
EcoZD: Overview
 ‘EcoHealth Approaches to the Better Management of
  Zoonotic Emerging Infectious Diseases in the Southeast
  Asia Region’
 Increase the knowledge, skills and capacity of research and
  infectious disease control personnel in Southeast Asia to
  understand the risks and impacts of Emerging Infectious
  Diseases and how feasible options can best be implemented
  and adapted;
 ‘Learning by Doing’ approach
 4 years 2008 – 2012; extended to Aug 2013
 6 countries in SE Asia region;
     Cambodia, China (Yunnan), Laos, Viet Nam, Indonesia, Thailand
 One of IDRC’s EcoHealth initiatives in SE Asia: APAIR/APEIR,
  EcoEID, BECA, FBLI
EcoZD: gestation
   The donor – IDRC www.idrc.ca & EcoHealth
   ILRI’s capacity
   Building on previous specific EID (EZD) initiative in
    the SE Asia region: APAIR
   Identify partners, point of contact, link to others
   Formation of research teams
   Develop and finalise research studies (incorporating
    aspects of EH)
   Mechanisms of implementation, funds transfer etc.
EcoZD: Components

Country Teams choices for research:
Cambodia: zoonotic risks for acute dysentery
China (Yunnan): Brucellosis & Toxoplasmosis
Indonesia: Rabies - Bali
Lao PDR: pig zoonoses (& non zoonoses)
Thai-Viet: hygiene in small-scale poultry
slaughterhouses
Viet Nam: zoonoses priority ranking

‘EcoHealth’ Resource Centres:
Chiang Mai University
University of Gadjah Mada
Cambodia
Partners:
•Centre for Livestock Development (CelAgrid, NGO)
•Department of Animal Health & Production
•Department of Communicable Disease Control
Research
•Review of public health data: diarrhoea reporting by SMS
•Choice of various low & high incidence areas (pilot sites)
•Household surveys: Questionnaires & PRA
•Longitudinal survey will follow selected households with
laboratory sampling
•Expected outputs – to ascertain proportion of acute dysentery
in rural households attributable
China – Yunnan province

Partners:
•Academy of Grassland & Animal Sciences
•Animal Science & Veterinary Institute
•Agriculture University
•Institute of Endemic Disease Control & Prevention
Research:
•Determine Brucellosis prevalence and priority in pilot
areas by compiling retrospective data, undertaking cross-
sectional surveys.
•Toxoplasmosis?
Indonesia

Partners:
•Centre for Veterinary & Analytical Studies (CIVAS)
•Disease Investigation Centre Denpasar
•Other experts
Research:
•Dog ecology: behaviour, demography , movement,
fecundity
•Socio-cultural relationship between people & dogs
•Community Engagement (dog registration, sterilisation)
Lao PDR

Partners:
•Department of Livestock Production, MAF
•Department of Hygiene & Prevention, MoH
•National Agriculture & Forestry Research Institute
Research:
•Prioritising pig diseases – both zoonoses & non-
zoonoses, by questionnaire and sampling 30 villages in
northern & southern provinces
•Building on earlier research by ACIAR, and indeed
followed by further ACIAR project
Thailand-Vietnam
Partners:
•Chiang Mai University, Veterinary Faculty
•Department of Livestock Development
•National Institute of Veterinary Research, Hanoi
•Sub-department of Animal Health, Hanoi
•(Originally China involved)
Research:
•Improving hygiene in small-scale poultry
slaughterhouses, beyond the upgrade hygiene produces
better quality of product - issues of sustainability, policy
implications
•Interview of slaughter-house owners, workers, market
traders etc
Vietnam

Partners:
•Pasteur Institute
•Nong Lam University
•Department of Animal Health
Research:
•Originally priority ranking of zoonoses, initial expert
opinion, retrospective phase to analyse surveillance
data, cross-sectional survey in pilot areas to ascertain
community priorities
Challenges: What language are we talking?

Lingua franca
      Eg Latin America/ EcoSalud
      ‘Lost in translation’
Biomedical v Social Sciences
      Medics & Vets (clinical / laboratory / epidemiology)
      Quantitative v Qualitative (ranking, dual health burden)
      Researchers, Decision Makers, Communities
Novel approaches to holistic integrated approaches
      One Health
      One Medicine
      EcoHealth
      Inexact / broad interpretation v H5N1
Case studies & publications
Challenges: Resource & Scope
Human Resources
Supply & Demand
        Language
        Technical – including proposal writing/ methodololgy / analysis /paper-writing
        Market forces operating
Identifying Champions (including to implement & to mentor)
Level of counterparts (senior v junior)
Scope of EcoZD
‘Carte blanche’ v prescriptive
Learning by doing (& making mistakes!)
Priority zoonoses +/- EID
EcoHealth approach – new ‘paradigm’
Two-dimensional capacity-building requirement
Greek temple analogy
EHRC concept
EcoZD: Some of the Solutions
   Cambodia: champions identified, Govt senior level
    support
   China: silo syndrome, local expert to provide
    technical assistance, EH training materials in
    Chinese
   Indonesia: multiple champions, finding niche - focus
    on dog ecology, complementing other initiatives
   Lao PDR: pooling inputs/outputs with ACIAR project
   Thai-Viet: reduced to 2 countries, local experts
    identified to provide technical assistance, link to
    EHRC-CMU
   Viet Nam: 3 research contracts and individual
    priorities, difficulties deciding on priority, change
    approach/angle
‘EcoHealth Resource Centres’

Partners:
•Chiang Mai University, Thailand
•Gadjah Mada University, Yogyakarta, Indonesia

Development
•Need for local capacity building
•Target audience of undergraduates/postgrads – more
open-minded(?)
•Need to engage senior academics
•Multiple disciplines (faculties) ‘under one roof’
‘EcoHealth Resource Centres’

• Provision of relevant training for staff, students and
  outside participants;
• Promotion of knowledge sharing and assimilation
  through making available books and peer-reviewed
  publications;
• Conducting multi/trans-disciplinary EcoHealth
  research activities involving post-graduate students;
• Preparing publications – from desktop/retrospective
  and prospective research; also position papers;
• Providing advocacy for EcoHealth – other universities,
  government and communities.
Yet more challenges

Definitions/ Standardisation for curriculum development
      One Health / One Medicine / EcoHealth
      Who’s right?
      Eg ILRI & USAID at CMU
Biomedical v Social Sciences
      Who leads?
      Quantitative v Qualitative – do they really mix?
      Will decision-makers & communities be convinced
Case studies & publications
      Vital to get peer-reviewed publications as well as local
       language articles
Beyond EcoZD

• EHRCs
   – Long term capacity building at various levels
   – No MSc or PhD of EcoHealth/OneHealth envisaged
   – Beyond communicable diseases
   – Own working definition and approach – refined as per
     context
   – Approach accepted – importance of ‘branding’
• Country Research Teams
   – Case studies fully synthesized (and lots of lessons learned will
     surely emerge)
   – Maintain relationships & potential further collaboration

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One Health approaches to prevent and control zoonoses

  • 1. One Health approaches to prevent and control zoonoses Jeffrey Gilbert, ILRI CIAT-Asia, Vientiane Agriculture, Fisheries & Conservation Department (AFCD) Workshop on “One Health: Past, Present, and Future” Hong Kong, 27 September 2011
  • 2. ILRI: Overview • One of 15 international research centers of CGIAR (Consultative Group on International Agricultural Research) • Individual Centres set up in 1960s (IRRI 1960, ILRAD 1973, ILCA 1974) • CGIAR 1971: 19 northern Govts + IGO (FAO,WB,ADB …) • ILRI founded 1994; headquarters in Nairobi, Kenya • ILRI focus – livestock, livelihoods, IAR4D • ILRI: organized in 4 research ‘themes’: markets, biotechnology, people-livestock-environment, poverty-gender-impact
  • 4. CG Reform  To overcome the challenges and exploit the opportunities, the CGIAR has undergone reform. A new Strategy and Results Framework (SRF) will, for the first time, allow the CGIAR centers to function as a unified system, working together to pursue shared goals  The 7 CGIAR Research Programmes* (formerly ‘mega-programmes’)  Objective – to harmonize  CRP-4: ‘Agriculture for Improved Health and Nutrition’ • This research program aims to accelerate progress in improving the nutrition and health of poor people by exploiting and enhancing the synergies between agriculture, nutrition, and health through four key research components: value chains, biofortification, control of agriculture-associated diseases, and integrated agriculture, nutrition, and health development programs and policies. With IFPRI and ILRI as co- Lead Centers, this program will also involve 10 other CGIAR Centers. It has an initial 3-year budget of US$191.4 million. * http://www.cgiarfund.org/cgiarfund/research_portfolio
  • 5. EcoHealth v OneHealth • Definitions open to debate: range from quite rigid to very flexible! • One-Health – biomedical focus: human + animal + wildlife; • EcoHealth: environment & socio-economic aspects – pioneered outside ‘traditional’ health • Personal opinion: OneHealth more theoretical, conceptual; EcoHealth more tangible? • Maybe it’s not so important … which ‘cola’
  • 6. EcoHealth v OneHealth • Option to discuss history of EH/OH
  • 7. EcoHealth One world – one health EcoHealth Human One Animal health Human Medicine health health Vet Pub O H. e n h e a l t h Agroecosystem health Societies Economies Institutions Adapted from Esther Schelling, STPH
  • 9. EcoHealth ‘Pillars’  Trans-disciplinary: inclusive vision, full involvement of Researchers, community & decision-makers;  Participation: consensus and cooperation not only within community, scientific & decision-making groups, but among them;  Equity: gender, ethnic group;  Sustainability.
  • 11. EcoZD: Overview  ‘EcoHealth Approaches to the Better Management of Zoonotic Emerging Infectious Diseases in the Southeast Asia Region’  Increase the knowledge, skills and capacity of research and infectious disease control personnel in Southeast Asia to understand the risks and impacts of Emerging Infectious Diseases and how feasible options can best be implemented and adapted;  ‘Learning by Doing’ approach  4 years 2008 – 2012; extended to Aug 2013  6 countries in SE Asia region;  Cambodia, China (Yunnan), Laos, Viet Nam, Indonesia, Thailand  One of IDRC’s EcoHealth initiatives in SE Asia: APAIR/APEIR, EcoEID, BECA, FBLI
  • 12. EcoZD: gestation  The donor – IDRC www.idrc.ca & EcoHealth  ILRI’s capacity  Building on previous specific EID (EZD) initiative in the SE Asia region: APAIR  Identify partners, point of contact, link to others  Formation of research teams  Develop and finalise research studies (incorporating aspects of EH)  Mechanisms of implementation, funds transfer etc.
  • 13. EcoZD: Components Country Teams choices for research: Cambodia: zoonotic risks for acute dysentery China (Yunnan): Brucellosis & Toxoplasmosis Indonesia: Rabies - Bali Lao PDR: pig zoonoses (& non zoonoses) Thai-Viet: hygiene in small-scale poultry slaughterhouses Viet Nam: zoonoses priority ranking ‘EcoHealth’ Resource Centres: Chiang Mai University University of Gadjah Mada
  • 14. Cambodia Partners: •Centre for Livestock Development (CelAgrid, NGO) •Department of Animal Health & Production •Department of Communicable Disease Control Research •Review of public health data: diarrhoea reporting by SMS •Choice of various low & high incidence areas (pilot sites) •Household surveys: Questionnaires & PRA •Longitudinal survey will follow selected households with laboratory sampling •Expected outputs – to ascertain proportion of acute dysentery in rural households attributable
  • 15. China – Yunnan province Partners: •Academy of Grassland & Animal Sciences •Animal Science & Veterinary Institute •Agriculture University •Institute of Endemic Disease Control & Prevention Research: •Determine Brucellosis prevalence and priority in pilot areas by compiling retrospective data, undertaking cross- sectional surveys. •Toxoplasmosis?
  • 16. Indonesia Partners: •Centre for Veterinary & Analytical Studies (CIVAS) •Disease Investigation Centre Denpasar •Other experts Research: •Dog ecology: behaviour, demography , movement, fecundity •Socio-cultural relationship between people & dogs •Community Engagement (dog registration, sterilisation)
  • 17. Lao PDR Partners: •Department of Livestock Production, MAF •Department of Hygiene & Prevention, MoH •National Agriculture & Forestry Research Institute Research: •Prioritising pig diseases – both zoonoses & non- zoonoses, by questionnaire and sampling 30 villages in northern & southern provinces •Building on earlier research by ACIAR, and indeed followed by further ACIAR project
  • 18. Thailand-Vietnam Partners: •Chiang Mai University, Veterinary Faculty •Department of Livestock Development •National Institute of Veterinary Research, Hanoi •Sub-department of Animal Health, Hanoi •(Originally China involved) Research: •Improving hygiene in small-scale poultry slaughterhouses, beyond the upgrade hygiene produces better quality of product - issues of sustainability, policy implications •Interview of slaughter-house owners, workers, market traders etc
  • 19. Vietnam Partners: •Pasteur Institute •Nong Lam University •Department of Animal Health Research: •Originally priority ranking of zoonoses, initial expert opinion, retrospective phase to analyse surveillance data, cross-sectional survey in pilot areas to ascertain community priorities
  • 20. Challenges: What language are we talking? Lingua franca  Eg Latin America/ EcoSalud  ‘Lost in translation’ Biomedical v Social Sciences  Medics & Vets (clinical / laboratory / epidemiology)  Quantitative v Qualitative (ranking, dual health burden)  Researchers, Decision Makers, Communities Novel approaches to holistic integrated approaches  One Health  One Medicine  EcoHealth  Inexact / broad interpretation v H5N1 Case studies & publications
  • 21. Challenges: Resource & Scope Human Resources Supply & Demand  Language  Technical – including proposal writing/ methodololgy / analysis /paper-writing  Market forces operating Identifying Champions (including to implement & to mentor) Level of counterparts (senior v junior) Scope of EcoZD ‘Carte blanche’ v prescriptive Learning by doing (& making mistakes!) Priority zoonoses +/- EID EcoHealth approach – new ‘paradigm’ Two-dimensional capacity-building requirement Greek temple analogy EHRC concept
  • 22. EcoZD: Some of the Solutions  Cambodia: champions identified, Govt senior level support  China: silo syndrome, local expert to provide technical assistance, EH training materials in Chinese  Indonesia: multiple champions, finding niche - focus on dog ecology, complementing other initiatives  Lao PDR: pooling inputs/outputs with ACIAR project  Thai-Viet: reduced to 2 countries, local experts identified to provide technical assistance, link to EHRC-CMU  Viet Nam: 3 research contracts and individual priorities, difficulties deciding on priority, change approach/angle
  • 23. ‘EcoHealth Resource Centres’ Partners: •Chiang Mai University, Thailand •Gadjah Mada University, Yogyakarta, Indonesia Development •Need for local capacity building •Target audience of undergraduates/postgrads – more open-minded(?) •Need to engage senior academics •Multiple disciplines (faculties) ‘under one roof’
  • 24. ‘EcoHealth Resource Centres’ • Provision of relevant training for staff, students and outside participants; • Promotion of knowledge sharing and assimilation through making available books and peer-reviewed publications; • Conducting multi/trans-disciplinary EcoHealth research activities involving post-graduate students; • Preparing publications – from desktop/retrospective and prospective research; also position papers; • Providing advocacy for EcoHealth – other universities, government and communities.
  • 25. Yet more challenges Definitions/ Standardisation for curriculum development  One Health / One Medicine / EcoHealth  Who’s right?  Eg ILRI & USAID at CMU Biomedical v Social Sciences  Who leads?  Quantitative v Qualitative – do they really mix?  Will decision-makers & communities be convinced Case studies & publications  Vital to get peer-reviewed publications as well as local language articles
  • 26. Beyond EcoZD • EHRCs – Long term capacity building at various levels – No MSc or PhD of EcoHealth/OneHealth envisaged – Beyond communicable diseases – Own working definition and approach – refined as per context – Approach accepted – importance of ‘branding’ • Country Research Teams – Case studies fully synthesized (and lots of lessons learned will surely emerge) – Maintain relationships & potential further collaboration

Hinweis der Redaktion

  1. Esther DVM
  2. Learning by doing: JG
  3. Senior level buy-in Selection of priority .. Syndromic surveillance; D ysentery versus ac watery diarrhoea
  4. H igh prevalence across N.China & Mongolia – internal spread ? R uminant movement W hich species Justification for adding toxoplasma
  5. S election M ore on
  6. S election M ore on