Mobility plays an important role in the cities by enabling people to carry out the most varied activities across the territory, as well as to ensure the city fully function. In addition, analogies to the human organism can be made by this urban dynamic, looking for solutions to specific issues. Moreover, this paper has been based by the premise that phenomena and urban elements could be conceptualized, explained and transformed from contemporary and innovative approaches applied in the medical field. For this reason, this paper aims to develop and present a new concept associated with urban mobility, based on the principles of regenerative medicine: the Regenerative Mobility, a concept with disruptive and evolutionary purposes. Furthermore, the structure of this paper is summarized by the introduction which contextualizes the theme, presents and characterizes the techniques used in the research. Additionally, the following chapters explore essential aspects of the city, explaining why it needs a mobility change and new concepts. Therefore, the concept of Regenerative Mobility is presented as a potential of mobility and cities improvement, followed by pragmatic cases, capable of illustrating some of its principles.