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Anatomy and embryology of female reproductive system

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Anatomy and embryology of female reproductive system

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by medical students: Haneen Salam
Hayder Qusay
Sama Qahir
Tabarak Ali
Hussein Ali
Anwer abdulkarim
Al- kindy college of medicine
Baghdad, Iraq

by medical students: Haneen Salam
Hayder Qusay
Sama Qahir
Tabarak Ali
Hussein Ali
Anwer abdulkarim
Al- kindy college of medicine
Baghdad, Iraq

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Anatomy and embryology of female reproductive system

  1. 1. Anatomy and embryology of female reproductive system Haneen Salam Hayder Qusay Sama Qahir Tabarak Ali Hussein Ali Anwer abdulkarim
  2. 2. ANATOMY OF THE FEMALE GENITAL SYSTEM
  3. 3. The external genitalia (vulva) 1. Mons pubis:  a fibrofatty pad overlying the symphysis pubis and covered by skin & hairs. 2. Clitoris:  a 0.5-3.5 cm erectile cavernous structure below the symphysis pubis. formed of a small glans and two corpora cavernosa.
  4. 4. 3. Labia Majora:  The outer 2 skin folds, raised by underlying adipose tissue, and passing back from the mons pubis to the perineum. The outer skin is covered by hairs while the inner medial surface is smooth, hairless and contains sebaceous and sweat glands. 4. Labia Minora:  two thin folds of modified skin situated medial to the labia majora.
  5. 5. 5. The Hymen: a membrane, situated about 2 cm from the vestibule that demarcates the external from the internal genital organs, and partially closes the vaginal orifice to allow menstruation. It ruptures during intercourse leaving remaining tags: carunculae myrtifomes.
  6. 6. 6. Bartholin Glands: (Greater Vestibular Glands): bilateral compound racemose glands secrete mucus during sexual excitement situated deep in the labia majora, at the junction of the posterior and the middle thirds Its duct is 2 cm long and opens between the hymen and the labium minus.
  7. 7. 7. Vestibule: the area between the inner aspects of the labia minora and the fourchette. Structures that open in the vestibule are: Urethra The Bartholin glands ducts. The vagina. 8. Vestibular bulbs: oblong masses of erectile tissue that lie on each side of the vaginal introitus 9. External urethral meatus: a triangular slit in the anterior part of the vestibule below the clitoris in which the urethra opens. 10. Skene’s duct: 2 blindly ending Para-urethral tubules which open in the floor of the urethra, few millimeters form the external urethral meatus.
  8. 8.  In the pre-pubertal vulva, no hair and little adipose deposition  during puberty pubic hair develops and fat deposits within the labia.  After menopause labia minora loses fat and become thinner while vaginal opening becomes smaller.
  9. 9. THE VAGINA A fibromuscular tube from the vulva to the uterus forming an angle of 60° with the horizontal plane. Length: anterior wall is 7 cm posterior wall is 9 cm Vaginal Fornices: The cervix projects in the upper blind end of the vagina that forms a pouch (vaginal pouch) around the cervix and is divided into four fornices : two lateral, anterior and posterior (deeper) fornices The internal reproductive organs:
  10. 10. Anatomical Relations of the Vagina Anteriorly: Upper 1/3: trigone of urinary bladder Lower 2/3: urethra. Posteriorly: Upper 1/3: peritoneum of Douglas pouch. Middle 1/3: ampulla of rectum. Lower 1/3: the perineal body. Laterally: Lower end: Bulbocavernosus muscle, vestibular bulb, and Bartholin gland. 1 cm above orifice: urogenital diaphragm 2½ cm above the orifice: levator ani muscle with the pelvic fascia above it. The lateral fornix gives attachment, to the lower part of the cardinal ligaments. The ureters pass through the cardinal ligaments 1 cm lateral to the vagina.
  11. 11. The epithelium is thick and rich with glycogen which increases in post-ovulatory phase.  The vagina is devoid of glycogen before puberty and after menopause due to lack of estrogen.  Doderlein’s bacillus is the normal vaginal flora that breaks glycogen to form lactic acid and produce a PH around 4.5, which protects the vagina by decreasing pathogenic bacterial growth. At birth the epithelium is well developed (maternal estrogen influence). After few weeks the epithelium atrophies and PH is 7, at puberty the reverse occurs and after menopause the vagina shrinks and the epithelium atrophies.
  12. 12. THE UTERUS
  13. 13. • The uterus is like an inverted pear tapering inferiorly to the cervix and situated entirely within the pelvis (the non-pregnant state). • It is 7.5cm length, 5cm width and 3cm thickness. • It is slightly larger in the multipara than in the nullipara
  14. 14. Divisions : 1. The corpus uteri: • Body that lies above the internal os • Cornu = the area of insertion of the fallopian tubes • Fundus lies above the insertion of the tubes. Three structures are attached to the cornu • round ligament anteriorly, • Fallopian tube centrally, • ovarian ligament posteriorly
  15. 15. 2. The isthmus: • An area 4-5 mm in length that lies between the anatomical internal os above, and the histological internal os below. It is lined by low columnar epithelium and few glands. • The isthmus expands during pregnancy forming the lower uterine segment (10 cm) during the last trimester.
  16. 16. 3-The cervix: • The elongated lower part of the uterus . • Measuring 2.5-3.0 cm. • Divided by the vaginal attachment into supravaginal portion above and vaginal portion (portio-vaginalis) below. • The cervical canal is the cavity that communicates above with the uterine cavity at the internal os and below with the vagina at the external os. • The external os is round in nulliparas and slit shaped in multiparas.
  17. 17. Relations of the Supravaginal cervix Anteriorly: Urinary bladder. Posteriorly: Forms the anterior wall of Douglas pouch. Laterally: 1/2 an inch lateral to the internal os the ureter is crossed by the uterine artery
  18. 18. Position : • The uterus is kept in an anteverted anteflexed position (AVF), with the external os lying at the level of the ischial spines, by the support of the cervical ligaments, endopelvic fascia and pelvic floor muscles (levator ani). • Anteversion: The uterus is inclined anteriorly to axis of the vagina. • Anteflexion: The body of the uterus is bent forwards upon the cervix.
  19. 19. THE FALLOPIAN TUBE • 2 tortuous tubes (10 cm in length) lie in the free upper part of the broad ligament. • They blend medially with the cornu of the uterus • Laterally their free outer end curves backwards towards the ovary. • Their lumen communicates between the uterine and the peritoneal cavities.
  20. 20. It has 4 parts: 1.The interstitial portion: lies within the wall of uterus. 2.The isthmus: the narrow part adjoining the uterus. 3.The ampulla: the widest and longest part. 4.The fimbrial portion (infundibulum): opens into the peritoneal cavity.
  21. 21. THE OVARY • The size and appearance of the ovaries depends on the age and stage of the menstrual cycle; they are small (1.5cm) in a child, they increase to adult size at puberty due to proliferation of stromal cells and follicle maturation (3cm length, 1cm width and 1cm thickness) . • After menopause they are small with wrinkled surface since no active follicles are present. • It is the only intra-peritoneal structure not covered by peritoneum.
  22. 22. Ovarian Attachments Three attachments: • The mesovarium: A peritoneal fold that suspends the ovary to the back of the broad ligament. • The infundibulopelivc ligament: suspends the upper pole of the ovary to the lateral pelvic wall and carries the ovarian vessels, nerves and lymphatics. • The ovarian ligament: attaches the lower pole to the cornu of the uterus.
  23. 23. Vestigial structures: Vestigial remains of the mesonephric ducts and tubules always present in young children but are variable structures in adults. •The epoophoron: a series of parallel blind tubules lie in the broad ligament between the mesovarium and fallopian tube. • The paroophoron: a few rudimentary tubules situated in the broad ligament between the epoophoron and the uterus. •The duct of Gartner: is the caudal part of the mesonephric duct, it runs alongside the uterus to the internal os.
  24. 24. The pelvic muscles • The pelvic diaphragm is a muscular partition formed by the levator ani and coccygei, with the pelvic fascia which covers their upper and lower surfaces. • It separates the pelvic cavity above from the perineal region below • Functions: support pelvic organs, and also plays an important sphinteric function in preventing urinary incontinence.
  25. 25. The iliococcygeus: ORIGIN: Posterior half of fascial line over obturator internus and ischial spine. INSERTION: Anococcygeal body. Ischiococcygeus Origin: ischial spine Insertion: lateral border of lower part of sacrum. ORIGIN: Posterior surface of pubis and anterior half of fascial line over obturator internus. INSERTION: Anococcygeal body. Pubococcygeus
  26. 26. Is made up of two layers of pelvic fascia which fill the gap between the descending pubic rami and lies beneath levator ani muscles. The deep transverse perineal muscles lie between the two layers and the diaphragm is pierced by the urethra and vagina. Urogenital diaphragm
  27. 27. • This is a mass of muscular tissue lies between the anal canal and lower third of the vagina. • Its apex is at the lower end of the rectovaginal septum where the rectum and posterior vaginal walls come in contact • Its base extends from the fourchette to the anus and covered with skin. • It is the point of insertion of the superficial perineal muscles and bounded above by levator ani muscles where they come into contact in the midline between posterior vaginal wall and rectum. The perineal body:
  28. 28. Anteriorly the uterus is covered with peritoneum only as far as the level of internal os, below this it is reflected onto the bladder forming the uterovescical pouch. The supravaginal cervix below this is separated from the bladder by connective tissue. The pelvic peritoneum
  29. 29. • Posteriorly the peritoneum covers the posterior surface of cervix and upper third of posterior vaginal wall forming the anterior boundary of the rectovaginal pouch of Douglas then reflects to the rectum. • Where the front and sides are covered by the peritoneum of rectovaginal pouch of Douglas, the middle third only the front is covered and the lower third have no peritoneal covering and the rectum is separated from the vagina by rectovaginal fascial septum
  30. 30. Ligaments • Broad ligament (it is not a ligament but a peritoneal fold). • The ovarian ligament: lies beneath the posterior layer of the broad ligament from the medial pole of the ovary to the uterus just below the point of entry of fallopian tubes. • The round ligament: is the continuation of the same structure and runs forward under the anterior leaf of peritoneum to enter the inguinal canal ending in the subcutaneous tissue of labia majora
  31. 31. THE PELVIC FASCIA The PARIETAL PELVIC FASCIA lines the wall of the pelvic cavity covering obturator and pyramidalis muscles. There is a thick tendinous arch on the side wall of the pelvis from which levator ani muscles arises and cardinal ligaments gain lateral attachment. It forms the upper layer of the urogenital diaphragm
  32. 32. Important parts of visceral fascia. • The cardinal ligaments are 2 strong fan-shaped fibromuscular bands passes from the cervix and vaginal vault to the side wall of the pelvis; they provide the essential support of the uterus and vaginal vault. • The uterosacral ligaments: run from the cervix and vaginal vault to the sacrum. • The bladder is supported laterally by condensation of visceral pelvic fascia on each side and by a sheet of pubocervical fascia which lies beneath it.
  33. 33. Pelvic blood supply: • 1.The ovarian artery arise from the aorta below the renal artery (because the ovary develops on the posterior abdominal wall and later migrates to the pelvis, it carries its blood supply from the abdominal aorta). The artery divides into branches that supply the ovary and tube and then anastomoses with the terminal branches of uterine artery
  34. 34. • 2.The internal iliac artery begins at the bifurcation of the common iliac artery, divides to anterior and posterior branches: the branches that supply the pelvic organs are all from the anterior division. • a.The uterine artery provides main blood supply of the uterus, from the base of the broad ligament it runs to the upper part of the uterus to anastomose with ovarian artery, in this part it send many branches into the substance of the uterus. Also supply branches to the ureter, cervix and upper vagina. • b.The vaginal artery supply the vagina. • c.The vescical arteries supply the bladder and terminal ureter
  35. 35. • d.The middle rectal artery arise in common with the lowest vescical artery. • e.The pudendal artery which leaves the pelvic cavity through the sciatic foramen entering the ischiorectal fossa giving the inferior rectal artery, its terminal branches supply the perineal and vulval arteries. • 3.The superior rectal artery: a continuation of inferior mesenteric artery that descends in the base of the mesocolon, divides into two branches supply the rectum.
  36. 36. • The pelvic veins: • Venous drainage from uterine, vaginal and vescical plexus is chiefly into the internal iliac veins. • Venous drainage from rectal plexus is via superior rectal veins to the inferior mesenteric veins, and the middle and inferior rectal veins to the internal pudendal and then to iliac veins
  37. 37. • The ovarian veins begins in the pumpiniform plexus between the broad ligament layers, the right vein ends in the inferior vena cava and the left in the left renal vein
  38. 38. • The pelvic lymphatics: • Lymphatic drainage from lower extremities, vulva and perineal regions is filtered through inguinal and superficial femoral nodes then along the deep pathway on the side wall of the pelvis lateral to major blood vessels forming the external iliac, common iliac and para-aortic group of nodes. Medially, another chain passes from the deep femoral nodes through femoral canal to obturator and internal iliac groups. The last group receives lymphatic from upper vagina, cervix and body of uterus. • From the internal and common iliac nodes to para- aortic chain and into the lumbar lymphatic trunks and cisterna chyli where all the lymph is carried by the thoracic duct to empty into the junction of left subclavian and internal jugular veins.
  39. 39. • Lymphatic drainage from genital tract: • The lower third of the vagina drains to the superficial lymph nodes while upper two thirds join the lymphatics of the cervix. • The cervix mostly drains to the internal iliac, obturator and external iliac nodes, but also directly to common iliac and lower para-aortic nodes. • The ovaries and fallopian tubes drain to para-aortic nodes, on the left they are found around left renal pedicle while on the right they flow into thoracic duct (early spread of metastatic carcinoma
  40. 40. Nerve supply of vulva and perineum: • The pudendal nerve arise from the second, third and fourth sacral nerves, passes along the outer wall of ischio-rectal fossa gives the inferior rectal branch and divides into perineal nerve and dorsal nerve of clitoris. The perineal nerve gives the sensory supply of the vulva and also the anterior part of external anal canal, levator ani and superficial perineal muscles. • The ilioinguinal and genitofemoral nerves supply sensory fibers to mons and labia and to first lumbar root. The posterior femoral cutaneous nerve carries sensation from perineum to the small sciatic nerve and thus to the first, second and third sacral nerves. Levator ani main supply is from third and fourth sacral nerves.
  41. 41. • Nerve supply of pelvic viscera: • All pelvic viscera receive sympathetic and parasympathetic innervations. Sympathetic nerves from preaortic plexus continue with those of superior hypogastric plexus which lies in front of the last lumbar vertebra which then divide and continue on each side with fibers passing beside the rectum to join inferior hypogastric (uterovaginal) plexus. • Parasympathetic fibers from second, third and fourth sacral nerves join uterovaginal plexus. Fibers from (or to) bladder, uterus, vagina and rectum join the plexus. • The ovaries innervated by the ovarian plexus which surrounds the ovarian vessels and join the preaortic plexus high up

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