presentation by hira naveed at abasyn university

1. “PESTE DES PETITS
VIRUS”
NAME: HIRA NAVEED

2. INTRODUCTION:
Peste des petits ruminants (PPR) also known as goat plague is an acute and highly contagious
viral infection of small ruminants (sheep, goats, etc.)

3. CAUSATIVE AGENT:
 PPR is caused by (PPRV), a member of morbillivirus group belonging to Paramyxoviridae
family. These viruses are enveloped, pleomorphic containing SSRNA, about 16 kb long.

4. Symptoms:
This disease is characterized by:
 pyrexia (<400c),
 oculo-nasal secretion,
 necrotic-stomatitis,
 pneumonia,
 respiratory distress,
 conjunctivitis,
 necrosis of mucous membranes
 gastroenteritis, which may results in diarrhea

5. SURVIVAL PERIOD:
 PPRV may remain alive at 60 0C for about 60 mints,
 PH ranging from 4.0 to 10.0
 Survival period is increased in frozen and chilled tissues but can be killed by high quality
disinfectants

6. TRANSMISSION:
 The transmission of the disease mainly occurs when there is a contact established between
susceptible and infected sheeps and goats.
 A large number of viruses are present in the secretions discharged from nose, eyes, mouth
and faeces.
 When infected animals sneeze or cough aerosols are resealed containing tremendous
amount of virus and get transferred to nearby susceptible animal.

7. EPIDEMIOLOGY:
 This disease was considered as restricted issue only in West Africa, but Now it is known
to exist in all over Africa.

8. DIAGNOSIS:
 In Pakistan, PRR was first reported in 1994 when the confirmative diagnosis was made by
PCR (polymerase chain reaction)
 This was additionally confirmed when the PPRV antigen was diagnosed during outbreaks
at different regions using indirect competitive enzyme-linked immunosorbent assay (Ic-
ELISA)