Árpád Figyelmesi (ChemAxon, Hungary) During the recent years like other segments, cheminformatics also entered the field of big data. As we see quick transition from the traditional methods towards the direction of need for handling significantly large sets of data often in unstructured or semistructured forms. Words and phrases like, terabytes, scalability, NoSQL, cloud solutions are integrated in our everyday language. I would like to present a few case studies to highlight key features of this transition. Such as sowing techniques and technologies for handling different aspects of this new area.