Cell No: + 91 8884118778
To obtain a challenging career leading to professional and personal growth in an organization
where the work demands high degree of skills that extensively utilizes and enhances my
knowledge and experience.
Syngene International Limited, India
A Contract Research & Manufacturing Organization provide drug discovery and development
include capabilities in medicinal chemistry, biology, in vivo pharmacology, toxicology, custom
synthesis, process R&D, cGMP manufacturing, formulation and analytical development.
Working as Associate Scientist in cell culture and downstream process development.
Handling shake flask and wave bioreactor.
Involved in downstream process development.
Downstream Processing: Affinity chromatography, Ion Exchange Chromatography,
Hydrophobic Interaction Chromatography and Gel Filtration Chromatography.
Hands on experience in Akta Pure, Akta Prime.
Lupin Limited, India
A Biotechnology company involved in Research & Development and Manufacturing of fusion
proteins and Monoclonal antibodies.
Worked as a manufacturing executive from 2012 June to 2014 June (2 Years)
2. Batch planning and execution of upstream processing, which involves preparation of
stainless steel bioreactor of 350 L volume and single use production bioreactor of 1000 L
Cell Bank preparation and seed expansion in small scale bioreactors.
Additional responsibilities includes keeping the facility cGMP complaint, inventory
management and man power management.
Biocon Biopharmaceuticals Pvt Limited, India:
A Largest biological facility in India. International standard State of Art cGMP plant
manufacturing drugs for Head and Neck Cancer, Breast Cancer and rheumatoid arthritis.
Worked as a Executive in manufacturing department from 2007 November to 2012 June (4
years 8 months)
Experience in Mammalian Cell Culture
6 + years of experience in NSO, CHO mammalian cell culture,
Hands on experience in Perfusion, Fed batch culture.
Preparation of Master Cell Bank/ Working Cell Bank.
Scale up of new process, technology transfer, Process optimization and Process validation.
Batch planning and execution.
Monitoring the cell culture process and maintain the critical process parameters within the
range. (pH, DO, Temperature, Back pressure etc).
Preparation of cell bank (MCB & WCB).
Seed development in shake flasks.
Preparation of Bioreactors and media storage vessels (cleaning in place, sterilization in place).
Preparation of aseptic filtration connection. Sterile filtration of Media, Buffer, Feeds, etc.
Preparation of glass ware’s and Autoclaving for the process requirements.
Media, Feeds and other additives preparations.
Performing integrity test for filters used in the process to check the integral of filters.
Raw materials ordering & follow up.
Planning activities, inventory & facility management
Man power management.
3. Qualification and Validation of Equipments
Involved in Qualification and Validation of equipments/instruments like Bioreactors
( stainless steel- up to 2 KL, Single use Bioreactor- up to 500 L), Autoclave, Dry heat
sterilizer, Biowelder and Biosealer, Integrity Tester, Blood Gas Analyzer, Cell Analyzer,
Cell Bank storage system, BSC & LAFU etc.
Prepared protocols for Qualification and Validation exercises as per the international
Data compilation and preparation of Reports from the validation study with suggestions for
2 x 1000 L single use bioreactor(Xcellerex) project.
Techno-commercial comparison of different manufacturers.
SAT: Installation & Operational qualification.
3 x 2000 L stainless steel bioreactor (Sartorius) project.
Involved in FAT & SAT.
Hands on experience in Sing use Bioreactor system, Operated leading Single use
Bioreactor systems from manufacturer like Sartorius, Thermo Scientific, Xcelerex.
1. Worked on Stainless steel Bioreactor up to 2 KL scale.
2. Disposable Bioreactors up to 500 L scale (RM Systems, Stirred Tank Reactor)
Completed PCT & CT batches well before the time period with 0% batch failure.
Successful commissioning and qualification of the 3 x 2 KL bioreactors.
4. Seminar Attended
Attended seminar on “Validations and Resolving Problems Related to Them” By Dr. Steven
Course: MSC Biotechnology
Institute: Kuvempu University
Course: BSC Biotechnology
Institute: Periyar University
MS office (MS Word, Excel, PowerPoint) Internet and data acquisition.
Date of Birth : 30th March 1985
Sex : Male
Nationality : Indian
Languages Known : English, Tamil and Hindi
Marital Status : Married
Passport number : J4696007
I, M.GOVARDHANAN do hereby confirm that the information given above is true to the best of
PLACE: Bangalore, India