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Scott Edmunds Data Dissemination:  Difficulties, Data Citation, DOIs and, (“Mo Data Mo Problems”)
The Ecoresponsive Genome of Daphnia pulexColbourne et al., Science4 February 2011:  200Mb Genome, 30,907 genes Duplicated genes most responsive to ecological challenges
Daphnia Genome Consortium wFleabase: 					Mar 2006 Genome release: 			July 2007 Genome Published:		Feb 2011 >58 companion papers https://daphnia.cgb.indiana.edu/Publications
Difficulties Flickr cc: opensourceway
Sequencing cost($ per Mbp) Moore’s Law ~100,000X Sequencing Source: E Lander/Broad
Sequencing Output Data Storage Moore’s/Kryders Law
Sequencing Output Data Publication Dissemination?
Potential sequencing capacity 1 IlluminaHiSeq 2000 (+Truseq upgrade)  = 600Gb/run (12 days) X 128 Hiseq= 6Tb/day = >2Pb/year = ~ 2000 Human Genomes/day
SRA Closure
Incentives/credit Credit where credit is overdue: “One option would be to provide researchers who release data to public repositories with a means of accreditation.” “An ability to search the literature for all online papers that used a particular data set would enable appropriate attribution for those who share. “ Nature Biotechnology 27, 579 (2009)  Prepublication data sharing  (Toronto International Data Release Workshop) “Data producers benefit from creating a citable reference, as it can later be used to reflect impact of the data sets.” Nature461, 168-170 (2009)
Datacitation: Datacite and DOIs Digital Object Identifiers (DOIs) offer a solution ,[object Object]
Researchers, authors, publishers know how to use them
Put datasets on the same playing field as articles Dataset Yancheva et al (2007). Analyses on sediment of Lake Maar. PANGAEA. doi:10.1594/PANGAEA.587840
Datacitation: Datacite and DOIs >1 million DOIs since Dec 2009 Central metadata repository to link with WoS/ISI - finally can track and credit use!
Coming soon… Large-Scale Data  Journal/Database In conjunction with: Editor-in-Chief: Laurie Goodman, PhD 	Editor: Scott Edmunds, PhD 	Assistant Editor: Alexandra Basford, PhD www.gigasciencejournal.com
Criteria and Focus of Journal/Database ,[object Object]
Utility/Usability
Standards/Searchability/Scale/Sharing
Data publishing/DOIwww.gigasciencejournal.com
Use of Data  = Importance   +  Usability easier to assess subjective?  www.gigasciencejournal.com
Reproducibility/Reuse ,[object Object]

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Scott Edmunds: Data Dissemination: Difficulties, Data Citation, DOI's (and GigaScience)

  • 1. Scott Edmunds Data Dissemination: Difficulties, Data Citation, DOIs and, (“Mo Data Mo Problems”)
  • 2. The Ecoresponsive Genome of Daphnia pulexColbourne et al., Science4 February 2011: 200Mb Genome, 30,907 genes Duplicated genes most responsive to ecological challenges
  • 3. Daphnia Genome Consortium wFleabase: Mar 2006 Genome release: July 2007 Genome Published: Feb 2011 >58 companion papers https://daphnia.cgb.indiana.edu/Publications
  • 4. Difficulties Flickr cc: opensourceway
  • 5. Sequencing cost($ per Mbp) Moore’s Law ~100,000X Sequencing Source: E Lander/Broad
  • 6. Sequencing Output Data Storage Moore’s/Kryders Law
  • 7. Sequencing Output Data Publication Dissemination?
  • 8. Potential sequencing capacity 1 IlluminaHiSeq 2000 (+Truseq upgrade) = 600Gb/run (12 days) X 128 Hiseq= 6Tb/day = >2Pb/year = ~ 2000 Human Genomes/day
  • 10. Incentives/credit Credit where credit is overdue: “One option would be to provide researchers who release data to public repositories with a means of accreditation.” “An ability to search the literature for all online papers that used a particular data set would enable appropriate attribution for those who share. “ Nature Biotechnology 27, 579 (2009) Prepublication data sharing (Toronto International Data Release Workshop) “Data producers benefit from creating a citable reference, as it can later be used to reflect impact of the data sets.” Nature461, 168-170 (2009)
  • 11.
  • 12. Researchers, authors, publishers know how to use them
  • 13. Put datasets on the same playing field as articles Dataset Yancheva et al (2007). Analyses on sediment of Lake Maar. PANGAEA. doi:10.1594/PANGAEA.587840
  • 14. Datacitation: Datacite and DOIs >1 million DOIs since Dec 2009 Central metadata repository to link with WoS/ISI - finally can track and credit use!
  • 15. Coming soon… Large-Scale Data Journal/Database In conjunction with: Editor-in-Chief: Laurie Goodman, PhD Editor: Scott Edmunds, PhD Assistant Editor: Alexandra Basford, PhD www.gigasciencejournal.com
  • 16.
  • 20. Use of Data = Importance + Usability easier to assess subjective? www.gigasciencejournal.com
  • 21.
  • 22. Integrated tools to promote more widespread access, viewing, and analysis of data.
  • 23. Encourage and aid use of workflow systems for methods (e.g. submission of Galaxy XML files).www.gigasciencejournal.com
  • 24.
  • 25. Allsupporting data must be publically available.
  • 26. Ask for MIBBI compliance and use of reporting checklists.
  • 27. Part of the Biosharing network.www.gigasciencejournal.com
  • 28.
  • 29. Data hosting will follow standard funding agency and community guidelines.
  • 30. DOI assignment available for submitted data to allow ease of findingand citing datasets, as well as for citation tracking.www.gigasciencejournal.com
  • 31. Our first DOI: To maximize its utility to the research community and aid those  fighting the current epidemic, genomic data is released here into the public domain under a CC0 license. Until the publication of research papers on the assembly and whole-genome analysis of this isolate we would ask you to cite this dataset as: Li, D; Xi, F; Zhao, M; Liang, Y; Chen, W; Cao, S; Xu, R; Wang, G; Wang, J; Zhang, Z; Li, Y; Cui, Y; Chang, C; Cui, C; Luo, Y; Qin, J; Li, S; Li, J; Peng, Y; Pu, F; Sun, Y; Chen,Y; Zong, Y; Ma, X; Yang, X; Cen, Z; Zhao, X; Chen, F; Yin, X; Song,Y ; Rohde, H; Li, Y; Wang, J; Wang, J and the Escherichia coli O104:H4 TY-2482 isolate genome sequencing consortium (2011) Genomic data from Escherichia coli O104:H4 isolate TY-2482. BGI Shenzhen. doi:10.5524/100001 http://dx.doi.org/10.5524/100001 To the extent possible under law, BGI Shenzhen has waived all copyright and related or neighboring rights to Genomic Data from the 2011 E. coli outbreak. This work is published from: China.
  • 32. E. Coli #crowdsourcing: the first tweenome?