This document discusses the management of open fractures and complications that can arise, including osteomyelitis. It provides guidelines from the British Infection Society and Ministry of Health Malaysia on antibiotic treatment for open fractures, which involves co-amoxiclav or cephalosporins within 3 hours, along with additional antibiotics like gentamicin during and after debridement. Post-traumatic osteomyelitis is described as a common complication where dead tissue leads to bone infection, usually treated with wound cleansing, stabilization, and prolonged antibiotics. Chronic osteomyelitis is also covered, where bone has been destroyed, leading to recurrent pain and discharging sinuses.