Directed evolution, a method used in protein engineering, is used to produce enzymes with many unique properties. The method mimics the process of natural selection to evolve proteins or nucleic acids toward a user-defined goal. The whole process is divided into two parts – mutagenesis of the gene encoding the enzyme to produce a library of variants, and selection of a particular variant based on its desirable catalytic properties. See More: https://bit.ly/30PKryi

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HOME / COURSE / TECHNOLOGY / CERTIFICATE IN DIRECTED EVOLUTION: ENGINEERING BIOCATALYSTS
Certi cate In Directed Evolution:
Engineering Biocatalysts
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Directed evolution, a method used in protein engineering, is used to produce enzymes with many
unique properties. The method mimics …
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Directed evolution, a method used in protein engineering, is used to produce enzymes with many
unique properties. The method mimics the process of natural selection to evolve proteins or nucleic
acids toward a user-de ned goal. The whole process is divided into two parts – mutagenesis of the
gene encoding the enzyme to produce a library of variants, and selection of a particular variant based
on its desirable catalytic properties.
The Certi cate In Directed Evolution: Engineering Biocatalysts course focuses on the process of
Directed evolution and analyses the enzymes types that are worth evolving. You will learn the
methods that are used for library generation and enzyme selection. The enzymes that are used in the
synthesis of drugs and biotechnological applications will also be focused on the course.
Assessment
This course does not involve any written exams. Students need to answer 5 assignment questions to
complete the course, the answers will be in the form of written work in pdf or word. Students can
write the answers in their own time. Each answer needs to be 200 words (1 Page). Once the answers
are submitted, the tutor will check and assess the work.
Certification
Edukite courses are free to study. To successfully complete a course you must submit all the
assignment of the course as part of assessment. Upon successful completion of a course, you can
choose to make your achievement formal by obtaining your Certi cate at a cost of £49.

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Course Credit: MIT
Introduction 00:10:00
Library generation by point mutation 00:15:00
Library generation by recombination 00:15:00
Alternative methods for library generation 00:15:00
Enzyme evolution by genetic complementation 00:10:00
Enzyme evolution by chemical complementation 00:20:00
Enzyme evolution using phage display 00:15:00
Enzyme evolution using bacterial cell surface display 00:10:00
Enzyme evolution using yeast surface display 00:10:00
Enzyme evolution using ribosome display 00:15:00
Enzyme evolution by in vitro compartmentalization 00:15:00
Alternative methods for enzyme/catalyst design 00:20:00
Assessment
Submit Your Assignment 00:00:00
COURSE CURRICULUM

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