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An Artificial Intelligence Company
Accelerating Biologic Therapies
Confidential and Proprietary
EVQLV develops
artificial intelligence
engineered with
life science data
to accelerate how
biologic therapies
reach those in need
AI-Powered Biologics Design
Artificial
Intelligence
NLP/NLG
Machine
learning
Probabilistic
classifier
Structural
modeling
Evolutionary
model
In silico
screening
Cloud
computing
Deep
learning
Biologics
Monoclonal
antibody
Peptide
Interferon
Single
domain
antibody
Interleukin
Nanobody
Fab
CAR T Life
Science
NGS
data
Toxicity
Receptor and
pathway
Molecular
biology
-Omics
data
Clinical trial
data
Crystal
structure
Confidential and Proprietary
Team
Brett
Averso
Data Science, MSc
Co-founder, CTO
EVQLV is built with years of experience in machine learning, molecular biology, oncology, software engineering,
agile development, structural biology, drug development, R&D partnerships, and computational biology.
Sabyasachi
Dash
Biotechnology, PhD
Life Science
Advisor
Jager
Hartman
Data Science, MSc
Data Scientist
Boris
Shor
Molecular Biology, PhD
Research &
Business Advisor
Stuart
Young
Bioinformatics, PhD
Data Architect
Daniel
Gigante
Sales/Marketing
Carsen
Klock
Software Engineer
Aarshay
Jain
Data Science, MSc
Data Scientist
Shauna
Soboh
Operations
Brett
Spurrier
Molecular Biophysics, PhD
Structural Biologist
Roland
Dunbrack
Biophysics, PhD
SciTech
Advisor
Andrew
Satz
Data Science, MSc
Co-founder, CEO
Confidential and Proprietary
Sarah
Yam
BioInformatics, MSc
BioInformatics
Market
$180 billion
US biologics market
38% of US prescriptions
are biologics
Confidential and Proprietary
Challenge
Biologic
Failure Rates >90%
12-14 Years to FDA
Approval of Biologics
Confidential and Proprietary
Asset Transaction
Values
Pharmaceutical Value Chain
Drug
Discovery
Pre-
Clinical
Phase I
Clinical
Trial
Drug in
Market
Phase II
Clinical
Trial
Phase III
Clinical
Trial
At EVQLV, we use artificial intelligence
to predict and reduce drug failure rates
73%
Fail
31%
Fail
36%
Fail
56%
Fail
30%
Fail
$105M $55M $140M $75M$105M $40M
Discovery &
Development Phase
Drug
Failure Rates
Confidential and Proprietary
Current Drug Discovery & Development Model
Pre-clinicalDrug Design
EVQLV Drug Design
<1 year | <$10 Million
Computational Design
and Optimization
4-5 years | $674 Million
In-vitro Discovery
EVQLV Value Proposition
Money Saved
Time Saved
>$500
Million
3-4 Yrs
Current Process
Length: 12-14 Yrs
Cost: $2.6B
Confidential and Proprietary
Pre-clinicalOptimizationValidationDiscovery
Business Models
Scalable fee-based model
through contracts generated
by partner organizations
Contract Research
Partnerships
Pharmaceutical
Collaborations
Direct fee-based model, mixed
with success-based milestone
payments and royalties
Licensable
Assets
Scalable and repeatable fee,
milestone, and royalty based
model
Confidential and Proprietary
Projected Annual Revenue
$20,000,000
$0
2020 2021 2022 2023 2024
$80,000,000
$60,000,000
$40,000,000
$43.6M
$75.6M
Total Revenue
Net Income
Total Expenses
Confidential and Proprietary
$24.8M
$9.3M
$600K
70
Collabs
110
Collabs
46
Collabs
24
Collabs
11
Collabs
Accomplishments Since January 2020
Product Business Development
2 research collaborations
7 LOIs being converted
into contracts
13 deals in negotiation
Computationally validated
algorithms; laboratory
results further validated
efficacy of our algorithm
Team
In less than 6 months,
grew from two founders
to 10 team members,
including eight
technologists
Confidential and Proprietary
EVQLV
Incorporation
Complete
AI + Ab Design
Validation
AI+Antibody
Design
Complete Sep
‘19
Dec
‘19Complete
Roadmap
Jan
‘20
Predictive Toxicity
and Targeting
✓
InitiateMar
‘20
Initiated
Partnership
Campaign
Feb
‘20
AI+Biological
Function
InitiateSep
‘20
AI+De Novo
Antibody Design
CompleteDec
‘20
AI+Target
Discovery
InitiateJan
‘21
AI+Clinical
Trial Design
InitiateJun
‘21
July
‘21
AI+Humanize &
AI+Patentability
CompleteDec
‘19
Initiate
Expand to
Add’l Biologics
Jan
‘21 Initiate
Jan
‘22 Initiate
Dec
‘21 Initiate
In Vitro
Studies
In Vivo
Studies
AI+Lab
Automation
✓
✓✓ ✓
✓
Confidential and Proprietary
info@evqlv.com
www.evqlv.com
New York, NY
Using Artificial Intelligence to
Accelerate the Speed at Which
Healing Reaches Those in Need

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EVQLV Deck

  • 1. An Artificial Intelligence Company Accelerating Biologic Therapies Confidential and Proprietary
  • 2. EVQLV develops artificial intelligence engineered with life science data to accelerate how biologic therapies reach those in need AI-Powered Biologics Design Artificial Intelligence NLP/NLG Machine learning Probabilistic classifier Structural modeling Evolutionary model In silico screening Cloud computing Deep learning Biologics Monoclonal antibody Peptide Interferon Single domain antibody Interleukin Nanobody Fab CAR T Life Science NGS data Toxicity Receptor and pathway Molecular biology -Omics data Clinical trial data Crystal structure Confidential and Proprietary
  • 3. Team Brett Averso Data Science, MSc Co-founder, CTO EVQLV is built with years of experience in machine learning, molecular biology, oncology, software engineering, agile development, structural biology, drug development, R&D partnerships, and computational biology. Sabyasachi Dash Biotechnology, PhD Life Science Advisor Jager Hartman Data Science, MSc Data Scientist Boris Shor Molecular Biology, PhD Research & Business Advisor Stuart Young Bioinformatics, PhD Data Architect Daniel Gigante Sales/Marketing Carsen Klock Software Engineer Aarshay Jain Data Science, MSc Data Scientist Shauna Soboh Operations Brett Spurrier Molecular Biophysics, PhD Structural Biologist Roland Dunbrack Biophysics, PhD SciTech Advisor Andrew Satz Data Science, MSc Co-founder, CEO Confidential and Proprietary Sarah Yam BioInformatics, MSc BioInformatics
  • 4. Market $180 billion US biologics market 38% of US prescriptions are biologics Confidential and Proprietary
  • 5. Challenge Biologic Failure Rates >90% 12-14 Years to FDA Approval of Biologics Confidential and Proprietary
  • 6. Asset Transaction Values Pharmaceutical Value Chain Drug Discovery Pre- Clinical Phase I Clinical Trial Drug in Market Phase II Clinical Trial Phase III Clinical Trial At EVQLV, we use artificial intelligence to predict and reduce drug failure rates 73% Fail 31% Fail 36% Fail 56% Fail 30% Fail $105M $55M $140M $75M$105M $40M Discovery & Development Phase Drug Failure Rates Confidential and Proprietary
  • 7. Current Drug Discovery & Development Model Pre-clinicalDrug Design EVQLV Drug Design <1 year | <$10 Million Computational Design and Optimization 4-5 years | $674 Million In-vitro Discovery EVQLV Value Proposition Money Saved Time Saved >$500 Million 3-4 Yrs Current Process Length: 12-14 Yrs Cost: $2.6B Confidential and Proprietary Pre-clinicalOptimizationValidationDiscovery
  • 8. Business Models Scalable fee-based model through contracts generated by partner organizations Contract Research Partnerships Pharmaceutical Collaborations Direct fee-based model, mixed with success-based milestone payments and royalties Licensable Assets Scalable and repeatable fee, milestone, and royalty based model Confidential and Proprietary
  • 9. Projected Annual Revenue $20,000,000 $0 2020 2021 2022 2023 2024 $80,000,000 $60,000,000 $40,000,000 $43.6M $75.6M Total Revenue Net Income Total Expenses Confidential and Proprietary $24.8M $9.3M $600K 70 Collabs 110 Collabs 46 Collabs 24 Collabs 11 Collabs
  • 10. Accomplishments Since January 2020 Product Business Development 2 research collaborations 7 LOIs being converted into contracts 13 deals in negotiation Computationally validated algorithms; laboratory results further validated efficacy of our algorithm Team In less than 6 months, grew from two founders to 10 team members, including eight technologists Confidential and Proprietary
  • 11. EVQLV Incorporation Complete AI + Ab Design Validation AI+Antibody Design Complete Sep ‘19 Dec ‘19Complete Roadmap Jan ‘20 Predictive Toxicity and Targeting ✓ InitiateMar ‘20 Initiated Partnership Campaign Feb ‘20 AI+Biological Function InitiateSep ‘20 AI+De Novo Antibody Design CompleteDec ‘20 AI+Target Discovery InitiateJan ‘21 AI+Clinical Trial Design InitiateJun ‘21 July ‘21 AI+Humanize & AI+Patentability CompleteDec ‘19 Initiate Expand to Add’l Biologics Jan ‘21 Initiate Jan ‘22 Initiate Dec ‘21 Initiate In Vitro Studies In Vivo Studies AI+Lab Automation ✓ ✓✓ ✓ ✓ Confidential and Proprietary
  • 12. info@evqlv.com www.evqlv.com New York, NY Using Artificial Intelligence to Accelerate the Speed at Which Healing Reaches Those in Need