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1. Chapter 10: Radicals
BY: DANIEL EISENSTEIN

2. Some things about radicals
 SP^2
 Trigonal planar

3. Radical stability

4. Radical Mechs
 Homolytic Cleavage
 Addition to a pi bond
 Hydrogen Abstraction
 Halogen Abstraction
 Elimination
 Coupling

5. Radical Mechs

6. But WAIT THERE IS MORE
 Homolytic cleavage=initiation
 Addition to pi bond, H abstraction, X abstraction and
elimination= propagation
 Coupling=termination
 Coupling and cleavage= opposites
 Hydrogen and halogen abstraction=opposites

7. 3 steps
 Initiation
 Propagation
 Termination

8. Radical Chlorination
 Homolytic cleavage
 Hydrogen abstraction
 Halogen Abstraction
 Coupling (3 ways to do it)

10. Radical initiators and inhibitors
 Initiators: heat, light, hydrogen peroxide
 Inhibitors: oxygen
 Radicals are actually really cool and important in
biology
 Just look at Superoxide dismutase
REALLY IMPORTANT ENZYME

11. Halogenation of Alkane
 Bromination is more selective than
chlorination

12. Bromination on an alkene
 Say we have propene
 We can do what we did in chapter 8
 We can do allylic bromination
 We can do both or choose one depending on the
reagents chosen

13. Radical Hydrohalogenation

14. Radical Polymerization

15. Mech