2. Safe Harbor Statement This presentation may contain certain âforward-looking statementsâ. All statements, other than statements of historical fact, that address activities, events or developments that we intend, expect, project, believe or anticipate will or may occur in the future are forward-looking statements. Such statements are based upon certain assumptions and assessments made by our management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate. The forward-looking statements included in this presentation are also subject to a number of material risks and uncertainties. We caution investors not to place undue reliance on the forward-looking statements contained in this presentation. We would advise reading our annual report filed with the United States Securities and Exchange Commission on Form 10-K for a more detailed description of these risks.
3. Enabling Practice of Regenerative Medicine Real-time Access to a Patientâs Own Regenerative Cells Unique Source Syringe of Cells Point-of-Care System â1 Hour Regenerative Cells Derived from Adipose Tissue (Fat)
16. Goal: Drive Cartridge Sales for Multiple Apps Cardiovascular Disease Plastic and Reconstructive Surgery 18K potential customers 1 consumable per day 6 mm + consumables/year Cell & Tissue Storage Open Op System: ID new âAppsâ and Fuel Pipeline
41. Celution: Discovering New Applications Selling systems to researchers to develop new âappsâ Investigator-sponsored trials taking place worldwide Radiation injury SUI Liver Renal Malignant wounds Cardiomyopathy Vocal cord paralysis HIV therapy-induced soft tissue atrophy Others Link: Most indications involve restoring blood flow to damaged tissue Cytori to select most-promising applications to advance or commercialize
60. Supplemental Product: PureGraftâą Natural Fill Optimizes fat graft prep Worldwide approval Complements CelutionÂź (EU) Celution lead qualifier (EU) Stand-alone product in US Convert users to CelutionÂź upon U.S. clearance Point-of-Entry: Building out US sales team (6 direct reps) Targets $1.7 bb dermal fill mkt 46K annual fat- grafting procedures in U.S. and growing
61. Supplemental Product: PureGraftâą Natural Fill Fat grafting is growing trend in plastic surgery Ideally suited for low cost consumer awareness campaign TV, print and radio outreach around customers Distributor model Sound Surgical is first in the US Multiple in Europe Minimal training requirements 1000 + shipped from Q2 2010 launch to YE 2010
63. Celution One: Next Generation Product Commercially available in Europe in 2011 Hospital-based system First system installed for ADVANCE Recon Formula transfer price Cardiac Other Apps Manufacturing JV Commercial rights
73. Strategic Equity (Dec. 10): $10 M investment from AstellasLong-term Debt: $20 million (GE/SVB/Oxford term loan) Shares Outstanding: 53 million as adjusted Revenue Growth 30
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79. Know-how, first mover, and $250 mm invested $60 MM (pro forma) in cash as of 9/30/10 Upcoming catalysts to support sales and advance pipeline 32
The Celution system is originally being marketed to 2 areas of regenerative medicine: reconstructive and aesthetic.The distinction of these two areas is in the location of the procedure and the general reimbursement of the procedure.