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Mitosis Cell Division

Miss Cybil N. Khumalo
University of Johannesburg
201212375@student.uj.ac.za
Cell Division
Cell Division

7 week old embryo

 Some cells divide constantly:

cells in the embryo, skin cells,
gut lining cells, etc.

Epithelial Cell

Intestinal Cell
Cell Division
 Other cells divide rarely or never.
Spinal Cord CellNerve cell

Cardiac Cell
Brain Cell – Nerve cell

(Heart Muscle)
Three reasons why cells reproduce
by asexual reproduction:

Skin cancer - the
abnormal growth of skin
cells - most often
develops on skin
exposed to the sun.
Cell that reproduce by
asexual reproduction
reproduce constantly.

1. Growth
2. Repair
3. Replacement
Cell Division Vocabulary
 somatic cell – a body cell; a cell whose genes
will not be passed on to future generations.

 sex or germ cell - a cell that is destined to
become a gamete (egg or sperm); a cell
whose genes can be passed on to future
generations.
Cell Division Vocabulary
 diploid (2N) – a cell with 2 chromosome
sets in each of its cells; all body (somatic)
cells

 haploid (N) – a cell with 1 chromosome set

in each of its cells; all gametes (sperm, eggs)
Cell Division
Pancreatic cells

 2 kinds of cell division:
 1. Mitosis: division of somatic cells
 2. Meiosis: creation of new sex cells

Sperm cells

Human egg cell
Cell Cycle
 A typical cell goes

through a process of
growth, development,
and reproduction
called the cell cycle.

 Most of the cycle is
called interphase.

INTERPHASE
Cell Cycle
 The longest

phase in the cell
cycle is
interphase.

 The 3 stages of

interphase are
called G1, S, and
G2 .
Cell Cycle
 Cells spend most of

their time in G1: it is
the time when the
cell grows and
performs its normal
function.
 Control of cell
division occurs in G1:
a cell that isn’t
destined to divide
goes into G0.
Cell Cycle
 The S phase

(“Synthesis”)
is the time
when the
DNA is
replicated.

Parent strands

Daughter strands
Cell Cycle
 G2 is the period
between S and
mitosis.

 DNA replication

is checked and the
cell is getting
ready to divide.
Cell Division
 All living cells come from other living cells.
 During mitosis, the nucleus of the cell
divides, forming two nuclei with identical
genetic information.
Animated Mitosis Cycle
http://www.cellsalive.com/mitosis.htm

• Interphase
• Prophase
• Metaphase
• Anaphase
• Telophase & Cytokinesis
Mitosis
 Mitosis produces two
genetically identical
cells.
 Mitosis is referred to
in the following
stages: prophase,
metaphase, anaphase,
and telophase.
Interphase
occurs before mitosis begins
• Chromosomes are copied (# doubles)
• Chromosomes appear as threadlike coils
(chromatin) at the start, but each chromosome
and its copy(sister chromosome) change to
sister chromatids at end of this phase
CELL MEMBRANE

Nucleus
Cytoplasm
Prophase
 In prophase, the cell begins the process of
division.

 The chromosomes condense.
duplicated
chromosome

chromatin
Prophase
 Nuclear envelope disappears.
Prophase
 Centrioles migrate

to opposite poles of
the cell.

 Asters and spindle
fibers form.

Aster and the mitotic apparatus
in an animal cell
Draw Prophase
Prophase
2
3

1

4
5
Prophase
Spindle fibers
Aster

Centriole

Centromere

Sister
chromatids
Metaphase
 The chromosomes

line up at the
equator of the cell
(metaphase plate),
with the centrioles at
opposite ends and
the spindle fibers
attached to the
centromeres.

Centriole
Spindle
fibers

Metaphase
plate

Centriole
Draw Metaphase
Anaphase
 In anaphase, the

centromeres divide.

 At this point, each

chromosome goes
from having 2 sister
chromatids to being 2
separate chromosomes
Anaphase
 The spindle fibers

contract and the
chromosomes are
pulled to opposite
poles.
Draw Anaphase
Telophase
 In telophase the cell
actually divides.

 The chromosomes are at
the poles of the cell.

 The nuclear envelope reforms around the two
sets of chromosomes.
Draw Telophase
Cytokinesis
 The division of the
cytoplasm.

 In animal cells, a

Cleavage Furrow
forms and separates
Daughter Cells
Cleavage furrow in a dividing frog cell.
Cytokinesis
 In plant cells, a Cell Plate forms
and separates Daughter Cells.

Cell Plate forming
ANIMAL VS. PLANT MITOSIS
 ANIMAL CELL
 Centriole and
aster present
 Daughter cells
separated by
cleavage furrow

 PLANT CELL
 No visible
centriole or aster
 Daughter cells
separated by cell
plate
Mitosis: Can you name the stages?

1
2

3

4
5
 Phases of mitosis - IPMATC
Interphase

Cytokinesis
References
Haver, J. (2013).Mitosis Cell Division. Available from: www.slideshare.net/jhaver/mitosis-p-p-t.
Kalember, M.R. (2014). Cell Division. Available from: www.slideshare,net/MRKALEMBER.
http://www.cellsalive.com/mitosis.htm

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Slideshare powerpoint

  • 1. Mitosis Cell Division Miss Cybil N. Khumalo University of Johannesburg 201212375@student.uj.ac.za
  • 3. Cell Division 7 week old embryo  Some cells divide constantly: cells in the embryo, skin cells, gut lining cells, etc. Epithelial Cell Intestinal Cell
  • 4. Cell Division  Other cells divide rarely or never. Spinal Cord CellNerve cell Cardiac Cell Brain Cell – Nerve cell (Heart Muscle)
  • 5. Three reasons why cells reproduce by asexual reproduction: Skin cancer - the abnormal growth of skin cells - most often develops on skin exposed to the sun. Cell that reproduce by asexual reproduction reproduce constantly. 1. Growth 2. Repair 3. Replacement
  • 6. Cell Division Vocabulary  somatic cell – a body cell; a cell whose genes will not be passed on to future generations.  sex or germ cell - a cell that is destined to become a gamete (egg or sperm); a cell whose genes can be passed on to future generations.
  • 7. Cell Division Vocabulary  diploid (2N) – a cell with 2 chromosome sets in each of its cells; all body (somatic) cells  haploid (N) – a cell with 1 chromosome set in each of its cells; all gametes (sperm, eggs)
  • 8. Cell Division Pancreatic cells  2 kinds of cell division:  1. Mitosis: division of somatic cells  2. Meiosis: creation of new sex cells Sperm cells Human egg cell
  • 9. Cell Cycle  A typical cell goes through a process of growth, development, and reproduction called the cell cycle.  Most of the cycle is called interphase. INTERPHASE
  • 10. Cell Cycle  The longest phase in the cell cycle is interphase.  The 3 stages of interphase are called G1, S, and G2 .
  • 11. Cell Cycle  Cells spend most of their time in G1: it is the time when the cell grows and performs its normal function.  Control of cell division occurs in G1: a cell that isn’t destined to divide goes into G0.
  • 12. Cell Cycle  The S phase (“Synthesis”) is the time when the DNA is replicated. Parent strands Daughter strands
  • 13. Cell Cycle  G2 is the period between S and mitosis.  DNA replication is checked and the cell is getting ready to divide.
  • 14.
  • 15. Cell Division  All living cells come from other living cells.  During mitosis, the nucleus of the cell divides, forming two nuclei with identical genetic information.
  • 16. Animated Mitosis Cycle http://www.cellsalive.com/mitosis.htm • Interphase • Prophase • Metaphase • Anaphase • Telophase & Cytokinesis
  • 17. Mitosis  Mitosis produces two genetically identical cells.  Mitosis is referred to in the following stages: prophase, metaphase, anaphase, and telophase.
  • 18. Interphase occurs before mitosis begins • Chromosomes are copied (# doubles) • Chromosomes appear as threadlike coils (chromatin) at the start, but each chromosome and its copy(sister chromosome) change to sister chromatids at end of this phase CELL MEMBRANE Nucleus Cytoplasm
  • 19. Prophase  In prophase, the cell begins the process of division.  The chromosomes condense.
  • 22. Prophase  Centrioles migrate to opposite poles of the cell.  Asters and spindle fibers form. Aster and the mitotic apparatus in an animal cell
  • 26. Metaphase  The chromosomes line up at the equator of the cell (metaphase plate), with the centrioles at opposite ends and the spindle fibers attached to the centromeres. Centriole Spindle fibers Metaphase plate Centriole
  • 27.
  • 29. Anaphase  In anaphase, the centromeres divide.  At this point, each chromosome goes from having 2 sister chromatids to being 2 separate chromosomes
  • 30. Anaphase  The spindle fibers contract and the chromosomes are pulled to opposite poles.
  • 32. Telophase  In telophase the cell actually divides.  The chromosomes are at the poles of the cell.  The nuclear envelope reforms around the two sets of chromosomes.
  • 34. Cytokinesis  The division of the cytoplasm.  In animal cells, a Cleavage Furrow forms and separates Daughter Cells Cleavage furrow in a dividing frog cell.
  • 35. Cytokinesis  In plant cells, a Cell Plate forms and separates Daughter Cells. Cell Plate forming
  • 36. ANIMAL VS. PLANT MITOSIS  ANIMAL CELL  Centriole and aster present  Daughter cells separated by cleavage furrow  PLANT CELL  No visible centriole or aster  Daughter cells separated by cell plate
  • 37. Mitosis: Can you name the stages? 1 2 3 4 5
  • 38.  Phases of mitosis - IPMATC Interphase Cytokinesis
  • 39. References Haver, J. (2013).Mitosis Cell Division. Available from: www.slideshare.net/jhaver/mitosis-p-p-t. Kalember, M.R. (2014). Cell Division. Available from: www.slideshare,net/MRKALEMBER. http://www.cellsalive.com/mitosis.htm