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CANALOPLASTY
  surgeryFAQ
        ?
Canaloplasty Surgery                                                                                                    1
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FAQ                                                                       Click to Watch Online!
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What is Canaloplasty?                                                                                                 21
Canaloplasty (pronounced Kah-NAL-oh-plas-tee)
is a new glaucoma treatment that gives many people                                                                   Last
with this potentially blinding condition the hope of
saving the vision they have. Canaloplasty can re-
duce pressure in the eye (IOP) by nearly 40%, and
many glaucoma patients who have had Canaloplasty                  CANALOPLASTY
no longer need medications. This “minimally inva-                  New Glaucoma Treatment
sive” procedure is available alone or can be done
with cataract extraction (phacocanaloplasty). It is a
“non-penetrating” surgical procedure that does not
require creation of a fistula nor result in a “bleb”
such as with traditional trabeculectomy surgery. In-
sertion of a micro-catheter into Schlemm’s canal
(the eye’s internal drainage duct) facilitates exit of    http://new-glaucoma-treatments.com/canaloplasty/
eye fluid through the natural outflow. The canal is
then dilated by injecting a sterile, gel-like material   suture is placed within the canal system. Suture ten-
called a viscoelastic. After the drainage channel is     sion within this system keeps it open for years re-
made larger the micro-catheter is removed and a          sulting in a controlled eye pressure.


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1
                                                               5

Why Canaloplasty?
                                                             10

Safety. Canaloplasty is safer than traditional glau-         15
coma surgery (trabeculectomy). If you are consid-
ering glaucoma surgery to prevent further vision             21
loss then choosing a surgery that has fewer risks
makes sense.                                                Last
Age. Younger patients need a better option than
traditional glaucoma surgery. Traditional glaucoma
surgery is less likely to succeed in younger patients
and carries a lifetime risk of infection. Success
with Canaloplasty is not age dependent and there is
no lifetime risk of infection.

Active Lifestyle. If you are an energetic person
who enjoys such activities as watersports, it is im-
portant for you to know that having traditional




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1
glaucoma surgery will severely limit your ability to     Difficulty with Glaucoma Medications. If                       5
participate in certain sports. No such limitation ex-    you are having trouble tolerating or affording your
ists with Canaloplasty. Once healed, patients who        glaucoma medications, then Canaloplasty may                  10
have had Canaloplasty are able to return to their        be an option for you. With traditional glaucoma
previous active lifestyles without restriction or lim-   surgeries, the risk is just too high to consider for         15
itation.                                                 reasons of financial hardship or side effects of
                                                         medicines alone.                                             21
Nearsighted. People who are very nearsighted
(highly myopic) are at a much higher risk of vision-     These are just some of the many reasons to con-
threatening complications from traditional glauco-
                                                                                                                     Last
                                                         sider Canaloplasty. If you have open angle glau-
ma surgeries. This is not true with Canaloplasty.        coma (the most common type) and are considering
                                                         glaucoma surgery, then you should explore your
Ethnicity. Traditional glaucoma surgery has a high       available options before making a decision. Al-
failure rate among black patients. In contrast, Ca-      though there are certainly instances where tradi-
naloplasty has a well-established track record of        tional glaucoma surgery is the best (or even only )
success among many races.                                option available, most patients with glaucoma are
                                                         candidates for Canaloplasty and should consider
Fear of Cataract. If you do not currently have a         this safer option.
cataract, you should know that the risk of devel-
oping one increases substantially after traditional
glaucoma surgery. This risk is much lower with
Canaloplasty.




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1
        How long has Canaloplasty been                    fluid to flow from the inside of the front of the
                                                          eye (anterior chamber) through the scleral hole to
                                                                                                                         1
        around? The answer to this question is
        not as straightforward as it might seem. Al-      a bleb (cyst, or blister-like elevation of the con-
                                                          junctiva). From here the fluid somehow finds its               5
though the iTrack catheter (required to perform
canaloplasty) has only been FDA approved since            way back into the venous system. These surgeries
2008, the surgical technique used to perform Ca-          are called “penetrating.” Canaloplasty, on the oth-          10
naloplasty has been around for decades. The mod-         er hand, is a non-penetrating (or “minimally inva-
ern procedure is essentially a modification of vis-       sive”) surgery because only a partial thickness flap         15
cocanalostomy, which was first described by Dr.           is created in the sclera. This flap is then sewn back
Stegmann in 1991. Because viscocanalostomy is a           in place after Schlemm’s canal is opened so there is         21
technically difficult surgery to perform, it was not      no fistula created between the inside and outside of
very popular among most eye surgeons. Howev-              the eye. Instead, fluid in the eye drains out through       Last
er, with the invention (and FDA approval) of the          the (newly opened) natural drainage system of the
iTrack, the impressive results and superior safety        eye.




                                                          3
profile of Canaloplasty have convinced a number
of surgeons (myself included) to become adept at                 How long does Canaloplasty take?
this procedure.                                                   Canaloplasty is not a quick surgery (at least




2
                                                                  by eye surgery standards). In order for the
       What does “Minimally Invasive” re-                 surgery to work properly, your surgeon must make
                                                          a flap in the sclera (the white part of the eye) and
       ally mean? Traditional glaucoma surger-
                                                          extend this all the way to a very thin and fragile
        ies (trabeculectomy or shunt surgery) re-
                                                          membrane called Descement’s membrane without
quire the creation of a full-thicknes hole (or fistula)
                                                          tearing it. This flap is created just above a vascu-
through the wall of the eye (sclera). This allows
                                                          lar tissue (which easily bleeds) called the choroid.
	    Fyodorov	SN,	Ioffe	DI,	Ronkina	TI:	[Glaucoma	sur-   All of this happens in a space no larger than the
gery—-	deep	sclerectomy].	Vestn	Oftalmol	4:6--10,	1982    fingernail on your “pinky” finger. It can be tedi-




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5
ous and requires both skill and patience from your                      Is Canaloplasty surgery painful?
surgeon. Thus, it can take anywhere between 45
                                                                                                                                1
                                                                         No. During surgery your eye will be anes-
minutes and two hours. The benefits, however, can                        thetized (numbed). After surgery you will be
last a lifetime.                                                 given drops to reduced inflammation and prevent
                                                                                                                                5


4
                                                                 pain. Generally, people do notice a “foreign body
        What if my natural drainage                              sensation” (scratchy sensation) under the upper
                                                                                                                              10
        canal cannot be fully                                    eyelid for up to a few weeks after surgery. This is
                                                                 caused by the slowly dissolving sutures and resolves         15
        catheterized? To get the full benefit of
Canaloplasty, it is important for your surgeon to                on its own. If you have Canaloplasty surgery and
canulate the full 360 degrees of Schlemm’s canal,                have more severe pain than what is described here,           21




                                                                 “
dilate the canal with viscoelastic, and stent it open            you should immediately contact your surgeon.
with a suture. The inability to complete any one of
                                                                                                                             Last
these elements (say, from prior scarring of the ca-
nal) can limit the effectiveness of the surgery. How-
ever, even if a full Canaloplasty procedure cannot
be completed, your surgeon can most likely convert
                                                                       If something doesn’t work, then
to either a traditional trabeculectomy or viscocana-                try something else. Because this
lostomy. A recent study confirmed that, while not                 new procedure is un-
as effective as Canaloplasty, viscocanalostomy can                  believable. I can’t say
significantly reduce the pressure in the eye provid-
ing for some protection from glaucoma.                              enough about it. I’m
                                                                    just thrilled. It’s like
	    Canaloplasty	 in	 One	 Eye	 Compared	With	Viscoca-           giving me a new life!
nalostomy	in	the	Contralateral	Eye	in	Patients	With	Bilateral	
Open-angle	Glaucoma.		Koerber,	N.		Journal	of	Glaucoma.	     	
Online	ahead	of	print,	January	26,	2011.




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Canaloplasty                                                                                                              1
                                                                                                                          5


ELIGIBILITY                                                                                                             10
                                                                                                                        15


6
       I’ve had glaucoma laser surgery.                    is not placed, this is called viscocanalostomy. Al-          21
       Can I have Canaloplasty? If you have                though not as effective as canalopasty, it can still
        had either of the laser surgeries for open         lower the IOP.                                              Last



         7
angle glaucoma (Argon Laser Trabeculoplasty or
Selective Laser Trabeculoplasty), you may still be                I’ve already had traditional glau-
a candidate for Canaloplasty. It depends, however,                coma surgery (trabeculectomy).
on how much scarring there is from the laser sur-                 Can I have Canaloplasty? The stand-
gery. Although your surgeon can visually inspect           ard answer would be “no.” However, it is possible
the area around Schelmm’s canal using a special            (though technically quite challenging) for Canalo-
contact lens (a technique called gonioscopy), s/he         plasty to be done in an eye that has already had a
cannot tell if there has been permanent scarring           trabeculectomy that is no longer functioning. If
of the canal itself. It may not be possible to fully       you and your surgeon are considering this option it
catheterize the canal if there is dense scarring of        is important for you to have realistic (guarded) ex-
the canal (called stenosis). In that case, your sur-       pectations of success. Many patients are interested
geon would not be able to stent the canal open with        in the option of Canaloplasty because (compared
a suture, but would still inject a special gel (called a   to other glaucoma surgeries) there are fewer risks.
viscoelastic) into the partially opened canal. When        But, if you are not the ideal candidate, there may
the canal cannot be fully canulated and the stent          also be less of a potential benefit.



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1


8        I’ve used glaucoma drops for a very                                                                                           5
         long time. Will that affect the suc-
         cess of Canaloplasty? Possibly. There                                                                                       10
is growing evidence that Schelmm’s canal (the eye’s
natural drainage duct) decreases in size with long-                                                        Find out if you            15
term use of glaucoma medications. If there is                                                             or your loved one
significant stenosis (scarring down) of the canal,                                                                                    21
then it may not be possible to thread the catheter
                                                                                                             qualifies for
all of the way around the canal. However, even                                                             Canaloplasty !            Last
if a stent cannot be left in the canal it is generally
possible to dilate a significant portion of the canal
with viscoelastic. When the cathether cannot be
fully threaded and a stent is not placed, this proce-                                                         Evaluation
dure is called viscocanalostomy. Viscocanalostomy                                                               Form
has been around since 1991 and is also an effective
treatment for glaucoma (though less so than Cana-                      http://new-glaucoma-treatments.com/canaloplasty-evaluation/
loplasty).

	     Dahan	 E,	 Drusedau	 MU:	 Nonpenetrating	 filtration	
surgery	 for	 glaucoma:	 control	 by	 surgery	 only.	 J	 Cataract	
Refract	Surg	26:695--701,	2000




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Canaloplasty                                                                                                           1
                                                                                                                       5

BENEFITS                                                                                                             10
                                                                                                                     15


9
       Will my vision change after                      healed (about three months after surgery) an inter-          21
       Canaloplasty? If you are hoping for bet-         esting thing happens: some patients note that their
       ter vision after canaloplasty, it is important   vision does seem better than it was prior to surgery.       Last
to point out that the purpose of any glaucoma treat-    This is likely because glaucoma drops worsen a con-
ment (incuding Canaloplasty) is to preserve vision,     dition called Tear Dysfunctional Syndrome that can
not improve it. That being said, your vision will       cause blurred vision. After successful Canaloplasty
change in the following ways after surgery. First,      surgery the need for glaucoma drops is reduced (or
expect your vision to be worse the first few days (or   even eliminated). Without these drops, Tear Dys-
even weeks) after surgery. This is expected. When       functional Syn-
Schlemm’s canal is dilated some blood refluxes          drome improves
back through the newly dilated canal into the eye.      which can
Some even consider this a sign of successful sur-       result in
gery. This blood eventually is cleared out the same     clearer
way it got into the eye. Another cause of (gener-       vision
ally temporary) fluctuations in vision is surgically    for some
induced astigmatism from the suture used to close       patients.
the surgical incision. This almost always resolves
by a month or so after surgery Once the eye is fully



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10
              Will Canaloplasty cure my                 who undergo Canaloplasty have lower IOPs after
                                                        surgery, but on average, they are able to stop just
                                                                                                                       1
              glaucoma? No. To date there is
               no cure for glaucoma. The best any       under two medications. What does “just under
                                                        two” mean? Well, some people are able to stop one              5
treatment can do is to halt (or slow) the progression
of this disease. The closer the IOP to 8mmHg, the       drop, some two, others none and some are even
better (below that and the eye can lose vision from     able to stop all of their drops. How many you will           10
the pressure being too low). Studies have shown         be able to stop if you have Canaloplasty cannot be
that for most glaucoma patients an IOP of less than     predicted, though it’s likely that you will be able to       15
15mmHg can be protective (a goal often achieved         stop at least one of them if you are on multiple
with Canaloplasty). Some forms of glaucoma (such        drops.                                                       21


                                                        12
as advanced, low tension, or normal tension glau-
coma) require IOPs of less than 12mmHg in order                        How long will my IOP stay                    Last
to avoid loss of vision. Only your eye surgeon can                     controlled with Canalo-
determine what your eye’s goal should be.                              plasty? Because Canaloplasty has



11
                                                        only been FDA approved since 2008, we only have
              Will I be able to stop using              three-year results. There is no reason, however, to
              glaucoma drops after Cana-                believe that the surgery will “stop working.” In a
              loplasty? Possibly. Remember that         study that looked at the long-term (7 year) results
the primary objective of any glaucoma surgery (in-      of combined cataract surgery and viscocanalosto-
cluding Canaloplasty) is to lower your IOP into a       my (the less effective precursor to Canaloplasty),
safer range and protect you from further loss of        IOP was reduced by over 33% (on average) at the
vision. A secondary goal would be to reduce (or         last documented visit. We can reasonably expect
even eliminate) the use of glaucoma drops. Studies      the long-term results of Canaloplasty and Phaco-
have shown Canaloplasty to be effective at achiev-      canaloplasty to be even better than those published
ing both of these goals. Not only do most people        for viscocanalostomy and Phacoviscocanalostomy.




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13
           What if Canaloplasty doesn’t               surgery (and at least for a few days, but sometimes
                                                      up to weeks after) your vision will be blurry in the
                                                                                                                     1
           work? Can I still have tradi-
                                                      eye that had canaloplasty. Therefore, any activities
           tional glaucoma surgery af-                                                                               5
                                                      that require good binocular vision (such as working
ter Canaloplasty? Yes. Having Canaloplasty            with heavy machinery) should be avoided until the
does not affect your abil-                                                     vision improves. Addition-          10
ity to have other types of                                                     ally, it is generally a good
glaucoma surgery at a later                                                    idea to keep the eye clean          15
date as long as your Ca-                                                       and dry (no gardening or
naloplasty surgeon oper-                                                       swimming) for at least a            21
ates in one of the superior                                                    few weeks. Once the inci-
“quadrants” of the eye.                                                        sion has healed over (about        Last
Some Canaloplasty sur-                                                         a month after surgery) it is
geons, however, operate                                                        generally OK to resume all
at what is called the 12:00                                                    of your usual activities.
position. This approach
can make it difficult (but                                                     Contrast this with tradi-
not impossible) for a sur-                                                     tional glacuoma surgery
geon to perform tradition-                                                    (trabeculectomy)      which
al glaucoma surgery at a later date.                  does limit your activities for the rest of your life.



14
                                                      Because of the fragile nature of a bleb after trab-
              I’m a very active person.               eculectomy (and the risk of rupture and/or infec-
              Will having Canaloplasty                tion), once someone has had trabeculectomy sur-
              force me to limit my activities?        gery s/he cannot participate in most water sports
The answer to this question depends on what time,     without high-quality protective eyewear.
after surgery, you are referring. Immediately after




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15
              I wear soft contact lenses. Can           get intraocular pressures (IOPs) under 12mmHg.
              I continue to wear them after             However, a recent head-to-head study comparing                  1
                                                        one year results of Canaloplasty vs. trabeculectomy
              Canaloplasty? Yes, but you may
                                                        showed no significant difference in average IOP                 5
have to wait until the eye is healed from surgery.
                                                        between the two surgeries. Granted, average IOP
How soon you may restart use of contact lenses
                                                        does not address the issue of the lowest IOP achiev-           10
will be up to your surgeon. Additionally, it may be
                                                        able. Nevertheless, some of my own patients who
necessary to get fitted for new contact lenses after
                                                        have had Canaloplasty now have pressures between
Canaloplasty as the surgery can sometimes change
                                                        8-10mmHg. This is by no means the average result,
                                                                                                                       15
your refractive error.
                                                        but does speak to the issue of whether it is possible
                                                        for Canaloplasty to lower the IOP below 10mmHg.
                                                                                                                       21
Contrast this with traditional glacuoma surgery



                                                        17
(trabeculectomy). Because of the fragile nature of                                                                    Last
a bleb after trabeculectomy (and the risk of rup-
                                                                        Is Canaloplasty really safer
ture and/or infection), once someone has had trab-                      than traditional glaucoma sur-
eculectomy surgery s/he cannot wear soft contact                        gery (trabeculectomy)? Yes. A
lenses after surgery for as long as the bleb is func-   recent study compared one year results of Cana-
tioning. Hard contact lenses, however, are gener-       loplasty vs. trabeculectomy. Although there was no
ally OK to wear even with trabeculectomy (though        significant difference in the final intraocular pres-
a refitting may be needed after surgery).               sures (IOPs) between the two surgeries (meaning
                                                        both surgeries were equally good at lowering IOP),
                                                        two differences were noted: (1) Canaloplasty patients



16
           I’ve heard that Canaloplasty                 experienced fewer side effects and complications
                                                        compared to those who had trabeculectomy; and (2)
           is not as effective as more
                                                        the patients who had Canaloplasty had better vision
           traditional glaucoma surgery                 than those patients who had trabeculectomy.
(trabeculectomy). Is this true? No, although
this is widely believed by many surgeons who do
not perform Canaloplasty. It has generally been         	    Non-Penetrating	Schlemm’s	Canaloplasty	versus	Trab-
                                                        eculectomy:	A	Head-to-Head	Comparison.		Tam	D,	Calafati	J,	
thought that trabeculectomy is the only way to          Ahmed	I.		[Submitted	for	publication,	December	2009].

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RISKS                                                                                                                       1
                                                                                                                            5

Canaloplasty                                                                                                               10
                                                                                                                           15
                                                                                                                           21


                18             What are                                                                                   Last
                                                        1. Bleeding in the eye. Almost 30% of people
                               the Risks of             who have Canaloplasty have some bleeding in the
                               Canaloplasty?            front of the eye. However, as mentioned earlier,
                Although it is true that there are      this bleeding (called a hyphema or microhyphema)
                fewer risks with Canaloplasty than      is pretty much to be expected (and may actually be
                there are with traditional glaucoma     desired ). This resolves with time and rarely causes
                surgery (trabeculectomy), it is not     any permanent reduction in vision.
                without risk. All surgeries (there
are no exceptions) have risks associated with them.     2. Intraocular pressure “spikes” during the heal-
The important thing to consider when faced with         ing period after surgery. About 5% (one in twenty)
the need for surgery is the relative risk of the pro-   people will have a short period after surgery when
cedure compared to going without the procedure.
                                                        	      Canaloplasty	 and	 Transient	 Anterior	 Chamber	
If your glaucoma is not under control then (given
                                                        Haemorrhage:	 a	 Prognostic	 Factor?	 	 Koch	 J,	 Heiligenhaus	
enough time) you will lose vision. Glaucoma sur-        A,	 Heinz	 C.	 Klinische	 Monatsblätter	 für	 Augenheilkunde	
geries offer a method of preventing that loss of        (Clinical	Journal	of	Ophthalmology)	2010	Nov	16.	(online	
vision. The most commonly encountered risks of          ahead	of	print).
Canaloplasty are:


                                                        © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
the IOP is actually higher than it was before sur-         ways resolve on their own. If it is not spontane-
gery. This almost always resolves.                         ously improving, it is generally possible for your
                                                                                                                          1
                                                           surgeon to inject a gas bubble in your eye to press
3. The formation of a bleb (blister) on the sur-           this membrane back against the cornea.                         5
face of the eye in the area of the incision (6%). It
is worth noting that with trabeculectomy, the for-         5. The need to perform traditional glaucoma                  10
mation of a stable bleb is necessary for success,          surgery (4%). Less than one in twenty Canalo-
while with Canaloplasty, it is considered to be an         plasty surgeries “fail” and must be converted to             15
undesireable outcome, or “risk.” These blebs rare-         either trabeculectomy or a “shunt.” This may be
ly limit the effectiveness of Canaloplasty. Howev-         done either at the time of initial surgery or at a           21
er, blebs can be associated with Tear Dysfunctional        later date. Your surgeon would make this decision
Syndrome (Dry Eye Syndrome) and could limit                as clinically appropriate.                                  Last
your ability to participate in certain activities (such
as certain water sports).                                  6. Hypotony (IOP too low). “Too low?” you may
                                                           be wondering, “I thought the problem was that
4. Descemet’s Membrane Separation, or De-                  the pressure was too high?” Well, if the IOP drops
tachment (3%). In order to open Schlemm’s canal,           below 5mmHg (millimeters of Mercury) and stays
a gel-like substance (called a viscoelastic) is injected   there, vision can be lost from a condition known as
into the canal. If the canal is particularly “tight”       “hypotony maculopathy.” Fortunately, this condi-
it is possible for the get to follow the path of least     tion is pretty rare with Canaloplasty (only one per-
resistance and dissect beneath Descement’s Mem-            son in 200 would be expected to have prolonged
brane (the thin film on the back of the cornea). If        hypotony). Compare this to trabeculectomy in
this happens, the vision could be affected. How-           which at least 1 out of every 10 people is likely to
ever, with time (weeks to months) these almost al-         experience hypotony.




                                                           © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
7. Infection. To date, vision-threatening infec-        als used to make the intraocular lenses (IOLs) in
tion of the eye (called “endophthalmitis”) has not      modern cataract surgery. It is very unlikely that
                                                                                                                       1
been documented with Canaloplasty. In theory,           this suture would ever erode into or through the
however, anytime an incision is made in the eye, an     eye wall as it is securely threaded through Sch-               5
infection could be possible. So, although the risk      lemm’s canal. In the few reported cases where the
seems to be less than 1 in 1,000, it’s probably not     suture has eroded into the anterior chamber it sel-          10
zero. Compare this to trabeculectomy which car-         dom causes any problem.
                                                                                                                     15

                                                                          20
ries up to a 5% chance per year of developing an
infection called “blebitis” that (if not caught early                                    What is the big
and treated) can result in endophthalmitis and loss                                      deal about a                21
of vision.                                                                               bleb, anyway?
                                                                          With traditional glaucoma sur-
                                                                                                                    Last
In summary, although not without risk, Canalo-                            gery (trabeculectomy), a blis-
plasty is associated with significantly fewer risks                       ter-like fluid collection (called a
(both in number and severity) than traditional glau-                      “bleb”) must be present on the
coma surgeries such as trabeculectomy                                     surface of the eye for the surgery



19
                                                                          to work. Aqueous fluid (the fluid
              I’m afraid of having some-                inside the eye) flows through the fistula into this
              thing placed in my eye. What              bleb where it then finds its way out of the eye. If
              are the risks of the stent? Al-           this bleb scars down, the the surgery fails and the
though this is an understandable concern, the only      intraocular pressure (IOP) goes back up potential-
thing left in the eye after Canaloplasty is a suture.   ly causing a further loss of vision from glaucoma.
The material used in this suture (polypropylene) has    Unfortunately, the body wants to scar down the
been used in eye surgery for decades and has a very     bleb as part of the natural healing response. In
good safety record. In fact, this material has been     order to prevent this from happening most modern
used in the eye far longer than most of the materi-     trabeculectomy surgeons use a chemical called an




                                                        © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
1
“antimetabolite” to preserve the bleb. The most              infection of the inside of the eye (endophthalmitis,           5
commonly used antimetabolite (Mitomycin-C, or                up to 1% per year) if not successfully treated. En-
MMC) causes permanent damage to the eye tissue               dophthalmitis often leads to severe loss of vision
in the area of the surgery.
                                                                                                                          10
                                                             or blindness. This risk continues for the life of the
                                                             patient unless the bleb scars down (fails).
The tissue exposed to MMC is very fragile and does
                                                                                                                          15
not heal well. Fluid in the bleb exerts pressure             Canaloplasty is a “blebless” (or bleb-free) pro-
which can result in what is called a “high bleb.”            cedure. With Canaloplasty no fistuas are created
                                                                                                                          21
This is essentially a thin bubble-shaped bleb. These         and there is no need to modify the natural healing
can cause (or may exacerbate) Tear Dysfunctional             of the eye. Without a bleb, there is no worsening           Last
Syndrome resulting in chronic irritation, tearing,           of Tear Dysfunctional Syndrome or risk of blebi-
and blurred vision. Because the wall of the bleb is          tis. Occasionally (about 6% of the time), a bleb will
so thin any trauma to the eye can rupture it. Since          spontaneously form with Canaloplasty. However,
it does not heal well any damage to the bleb may             because most Canaloplasty surgeons do not use
require surgical revision.                                   MMC, the bleb is usually “shallow” and unlikely to
                                                             result in Tear Dysfunctional Syndrom or blebitis.
Finally, and most concerning, is that when MMC
is used during trabeculectomy, there is up to a 5%
risk per year of bleb leak which can progress to

	    Greenfield	DS,	Suñer	IJ,	Miller	MP,	Kangas	TA,	
Palmberg	PF,	Flynn	HW	Jr.	Endophthalmitis	after	filtering	
surgery	with	mitomycin.	Arch	Ophthalmol	1996;114:943-
949.




                                                             © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
Surgeons  References                                                                     1


Canaloplasty
                                                                                          5
                                                                                        10
                                                                                        15
                                                                                        21
                                                                                       Last



          21
                         Are all Canaloplasty surgeons Glaucoma
                         Specialists? No. For example, Dr. Richardson
                         is not a glaucoma specialist. A glaucoma specialist
          is someone who spends one to two additional years after resi-
          dency learning how to deal with advanced and unusual forms of
          glaucoma. Because Canaloplasty can most effectively treat ear-
          lier (less advanced) forms of the more common types of open
          angle glaucoma, it is often performed by general ophthalmolo-
          gists and/or cataract surgeons. Indeed, it is particularly effective
          when done at the same time as cataract surgery - in which case it
          is called “phacocanaloplasty.”




                           © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
22
           What training is required to
           become an Interventional
           Ophthalmologist        (Canalo-
plasty Surgeon)? Interventional Ophthalmolo-
                                                        23             Where can I find a
                                                                       Canaloplasty surgeon
                                                                       near me?
                                                        • Visit the iScience website. This site will provide a
                                                        list of Canaloplasty surgeons near you.
                                                                                                                        1
                                                                                                                        5
gists must first complete their training as EyeMDs                                                                     10


                                                        24
(completion of a bachelor’s degree followed by
four years of medical school, one year of intern-                      How much does Canaloplasty                      15
ship, and three years of residency training in eye                     cost? The amount charged for ca-
diseases and surgery). Once proficient as an eye                       naloplasty varies by surgeon and sur-           21
surgeon, an ophthalmologist can request to be           gery center. If you do not have insurance, the total
trained in the technique of Canaloplasty. Doctors       cost for canaloplasty can range from $5,000 to up-            Last
are required to complete a “wet-lab” (practice on       wards of $10,000 per eye. Fortunately, Medicare
cadaver eyes) prior to performing Canaloplasty sur-     and many insurances pay for Canaloplasty when
                 gery on humans. Then, the first 10     surgical treatment of glaucoma is indicated. Even
                 surgeries are conducted under the      if you do not have insurance, however, Canalo-
                 direct monitoring of a Clinical Spe-   plasty can pay for itself over time simply by saving
                 cialist. Only a fraction of surgeons   you $1,000s per year in the cost of glaucoma drops
                            who start the Canalo-       that may no longer be necessary after this surgery.
                            plasty training complete
                            the monitoring require-
                                                        	    http://canaloplasty.com/iscience/find_a_physician.php
                            ments and go on to be-
                              come Canaloplasty sur-
                              geons.




                                                        © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
25
 Where can I learn more about Canaloplasty?
 Below are some additional resources that could help you to decide if Canaloplasty is right for
 you:
                                                                                                                   1
                                                                                                                   5

     1. Canaloplasty.com - Created by iScience, the manufacturer of the catheter used in Cana-                   10
     loplasty. This is where you would go to find a Canaloplasty surgeon near you.
                                                                                                                 15
     2. YouTube.com - If you want to see what this surgery actually looks like (and aren’t too
     squeamish).                                                                                                 21
     3. Google Alerts - You will need a Google account for this. Set up an alert with the word                  Last
     “canaloplasty” in it and Google will send you an email whenever it finds a new article, post,
     or video about Canaloplasty.



                                         Find out if you            4. Find a Canalplasty sur-
                                                                    geon and schedule a consul-
                                        or your loved one
                                                                    tation - There is no better way
                                           qualifies for            to find out if Canaloplasty is
                                         Canaloplasty !             right for you than to have your
                                                                    eye evaluated by a surgeon cer-
                                                                    tified to perform Canaloplasty.

                                            Evaluation
                                              Form
     http://new-glaucoma-treatments.com/canaloplasty-evaluation/

                                                    © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
Thank You for Reading!
I hope you learned something of value.

                                                         Dr. David Richardson has performed thousands of
                                                         eye surgeries using the most advanced techniques. He is
                                                         trusted not only by thousands of patients, but also by oth-
                                                         er medical professionals.

                                                          In a series of surveys, medical professionals were asked a
                                                          simple question: “If you needed medical care, which doc-
                                                          tor would you choose?” Based on the results of these sur-
                                                          veys, Dr. Richardson was named a “Super Doctor” by his
                                                          peers in the Los Angeles Magazine in 2010  2011. In a
                                                          similar survey conducted by Pasadena Magazine, Dr. Ri-
        http://new-glaucoma-treatments.com/contact-form/ chardson was also voted as a “Top Doc” for the past 3
                                                         consecutive years (2008, 2009 and 2010). Actions, though,
                          speak louder than words - Dr. Richardson is the personal eye surgeon for many of the
     Contact              most respected doctors in the San Gabriel valley. Dr. David Richardson is among a select
 Dr. Richardson           group of ophthalmologists in Southern California offering Canaloplasty as a treatment
                          option for his glaucoma patients. For more canaloplasty information by Dr. David Rich-
                          ardson, please visit New-Glaucoma-Treatments.com

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Canaloplasty Surgery FAQ by Dr. David Richardson

  • 2. Canaloplasty Surgery 1 5 FAQ Click to Watch Online! 10 15 What is Canaloplasty? 21 Canaloplasty (pronounced Kah-NAL-oh-plas-tee) is a new glaucoma treatment that gives many people Last with this potentially blinding condition the hope of saving the vision they have. Canaloplasty can re- duce pressure in the eye (IOP) by nearly 40%, and many glaucoma patients who have had Canaloplasty CANALOPLASTY no longer need medications. This “minimally inva- New Glaucoma Treatment sive” procedure is available alone or can be done with cataract extraction (phacocanaloplasty). It is a “non-penetrating” surgical procedure that does not require creation of a fistula nor result in a “bleb” such as with traditional trabeculectomy surgery. In- sertion of a micro-catheter into Schlemm’s canal (the eye’s internal drainage duct) facilitates exit of http://new-glaucoma-treatments.com/canaloplasty/ eye fluid through the natural outflow. The canal is then dilated by injecting a sterile, gel-like material suture is placed within the canal system. Suture ten- called a viscoelastic. After the drainage channel is sion within this system keeps it open for years re- made larger the micro-catheter is removed and a sulting in a controlled eye pressure. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 3. 1 5 Why Canaloplasty? 10 Safety. Canaloplasty is safer than traditional glau- 15 coma surgery (trabeculectomy). If you are consid- ering glaucoma surgery to prevent further vision 21 loss then choosing a surgery that has fewer risks makes sense. Last Age. Younger patients need a better option than traditional glaucoma surgery. Traditional glaucoma surgery is less likely to succeed in younger patients and carries a lifetime risk of infection. Success with Canaloplasty is not age dependent and there is no lifetime risk of infection. Active Lifestyle. If you are an energetic person who enjoys such activities as watersports, it is im- portant for you to know that having traditional © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 4. 1 glaucoma surgery will severely limit your ability to Difficulty with Glaucoma Medications. If 5 participate in certain sports. No such limitation ex- you are having trouble tolerating or affording your ists with Canaloplasty. Once healed, patients who glaucoma medications, then Canaloplasty may 10 have had Canaloplasty are able to return to their be an option for you. With traditional glaucoma previous active lifestyles without restriction or lim- surgeries, the risk is just too high to consider for 15 itation. reasons of financial hardship or side effects of medicines alone. 21 Nearsighted. People who are very nearsighted (highly myopic) are at a much higher risk of vision- These are just some of the many reasons to con- threatening complications from traditional glauco- Last sider Canaloplasty. If you have open angle glau- ma surgeries. This is not true with Canaloplasty. coma (the most common type) and are considering glaucoma surgery, then you should explore your Ethnicity. Traditional glaucoma surgery has a high available options before making a decision. Al- failure rate among black patients. In contrast, Ca- though there are certainly instances where tradi- naloplasty has a well-established track record of tional glaucoma surgery is the best (or even only ) success among many races. option available, most patients with glaucoma are candidates for Canaloplasty and should consider Fear of Cataract. If you do not currently have a this safer option. cataract, you should know that the risk of devel- oping one increases substantially after traditional glaucoma surgery. This risk is much lower with Canaloplasty. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 5. 1 How long has Canaloplasty been fluid to flow from the inside of the front of the eye (anterior chamber) through the scleral hole to 1 around? The answer to this question is not as straightforward as it might seem. Al- a bleb (cyst, or blister-like elevation of the con- junctiva). From here the fluid somehow finds its 5 though the iTrack catheter (required to perform canaloplasty) has only been FDA approved since way back into the venous system. These surgeries 2008, the surgical technique used to perform Ca- are called “penetrating.” Canaloplasty, on the oth- 10 naloplasty has been around for decades. The mod- er hand, is a non-penetrating (or “minimally inva- ern procedure is essentially a modification of vis- sive”) surgery because only a partial thickness flap 15 cocanalostomy, which was first described by Dr. is created in the sclera. This flap is then sewn back Stegmann in 1991. Because viscocanalostomy is a in place after Schlemm’s canal is opened so there is 21 technically difficult surgery to perform, it was not no fistula created between the inside and outside of very popular among most eye surgeons. Howev- the eye. Instead, fluid in the eye drains out through Last er, with the invention (and FDA approval) of the the (newly opened) natural drainage system of the iTrack, the impressive results and superior safety eye. 3 profile of Canaloplasty have convinced a number of surgeons (myself included) to become adept at How long does Canaloplasty take? this procedure. Canaloplasty is not a quick surgery (at least 2 by eye surgery standards). In order for the What does “Minimally Invasive” re- surgery to work properly, your surgeon must make a flap in the sclera (the white part of the eye) and ally mean? Traditional glaucoma surger- extend this all the way to a very thin and fragile ies (trabeculectomy or shunt surgery) re- membrane called Descement’s membrane without quire the creation of a full-thicknes hole (or fistula) tearing it. This flap is created just above a vascu- through the wall of the eye (sclera). This allows lar tissue (which easily bleeds) called the choroid. Fyodorov SN, Ioffe DI, Ronkina TI: [Glaucoma sur- All of this happens in a space no larger than the gery—- deep sclerectomy]. Vestn Oftalmol 4:6--10, 1982 fingernail on your “pinky” finger. It can be tedi- © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 6. 5 ous and requires both skill and patience from your Is Canaloplasty surgery painful? surgeon. Thus, it can take anywhere between 45 1 No. During surgery your eye will be anes- minutes and two hours. The benefits, however, can thetized (numbed). After surgery you will be last a lifetime. given drops to reduced inflammation and prevent 5 4 pain. Generally, people do notice a “foreign body What if my natural drainage sensation” (scratchy sensation) under the upper 10 canal cannot be fully eyelid for up to a few weeks after surgery. This is caused by the slowly dissolving sutures and resolves 15 catheterized? To get the full benefit of Canaloplasty, it is important for your surgeon to on its own. If you have Canaloplasty surgery and canulate the full 360 degrees of Schlemm’s canal, have more severe pain than what is described here, 21 “ dilate the canal with viscoelastic, and stent it open you should immediately contact your surgeon. with a suture. The inability to complete any one of Last these elements (say, from prior scarring of the ca- nal) can limit the effectiveness of the surgery. How- ever, even if a full Canaloplasty procedure cannot be completed, your surgeon can most likely convert If something doesn’t work, then to either a traditional trabeculectomy or viscocana- try something else. Because this lostomy. A recent study confirmed that, while not new procedure is un- as effective as Canaloplasty, viscocanalostomy can believable. I can’t say significantly reduce the pressure in the eye provid- ing for some protection from glaucoma. enough about it. I’m just thrilled. It’s like Canaloplasty in One Eye Compared With Viscoca- giving me a new life! nalostomy in the Contralateral Eye in Patients With Bilateral Open-angle Glaucoma. Koerber, N. Journal of Glaucoma. Online ahead of print, January 26, 2011. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 7. Canaloplasty 1 5 ELIGIBILITY 10 15 6 I’ve had glaucoma laser surgery. is not placed, this is called viscocanalostomy. Al- 21 Can I have Canaloplasty? If you have though not as effective as canalopasty, it can still had either of the laser surgeries for open lower the IOP. Last 7 angle glaucoma (Argon Laser Trabeculoplasty or Selective Laser Trabeculoplasty), you may still be I’ve already had traditional glau- a candidate for Canaloplasty. It depends, however, coma surgery (trabeculectomy). on how much scarring there is from the laser sur- Can I have Canaloplasty? The stand- gery. Although your surgeon can visually inspect ard answer would be “no.” However, it is possible the area around Schelmm’s canal using a special (though technically quite challenging) for Canalo- contact lens (a technique called gonioscopy), s/he plasty to be done in an eye that has already had a cannot tell if there has been permanent scarring trabeculectomy that is no longer functioning. If of the canal itself. It may not be possible to fully you and your surgeon are considering this option it catheterize the canal if there is dense scarring of is important for you to have realistic (guarded) ex- the canal (called stenosis). In that case, your sur- pectations of success. Many patients are interested geon would not be able to stent the canal open with in the option of Canaloplasty because (compared a suture, but would still inject a special gel (called a to other glaucoma surgeries) there are fewer risks. viscoelastic) into the partially opened canal. When But, if you are not the ideal candidate, there may the canal cannot be fully canulated and the stent also be less of a potential benefit. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 8. 1 8 I’ve used glaucoma drops for a very 5 long time. Will that affect the suc- cess of Canaloplasty? Possibly. There 10 is growing evidence that Schelmm’s canal (the eye’s natural drainage duct) decreases in size with long- Find out if you 15 term use of glaucoma medications. If there is or your loved one significant stenosis (scarring down) of the canal, 21 then it may not be possible to thread the catheter qualifies for all of the way around the canal. However, even Canaloplasty ! Last if a stent cannot be left in the canal it is generally possible to dilate a significant portion of the canal with viscoelastic. When the cathether cannot be fully threaded and a stent is not placed, this proce- Evaluation dure is called viscocanalostomy. Viscocanalostomy Form has been around since 1991 and is also an effective treatment for glaucoma (though less so than Cana- http://new-glaucoma-treatments.com/canaloplasty-evaluation/ loplasty). Dahan E, Drusedau MU: Nonpenetrating filtration surgery for glaucoma: control by surgery only. J Cataract Refract Surg 26:695--701, 2000 © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 9. Canaloplasty 1 5 BENEFITS 10 15 9 Will my vision change after healed (about three months after surgery) an inter- 21 Canaloplasty? If you are hoping for bet- esting thing happens: some patients note that their ter vision after canaloplasty, it is important vision does seem better than it was prior to surgery. Last to point out that the purpose of any glaucoma treat- This is likely because glaucoma drops worsen a con- ment (incuding Canaloplasty) is to preserve vision, dition called Tear Dysfunctional Syndrome that can not improve it. That being said, your vision will cause blurred vision. After successful Canaloplasty change in the following ways after surgery. First, surgery the need for glaucoma drops is reduced (or expect your vision to be worse the first few days (or even eliminated). Without these drops, Tear Dys- even weeks) after surgery. This is expected. When functional Syn- Schlemm’s canal is dilated some blood refluxes drome improves back through the newly dilated canal into the eye. which can Some even consider this a sign of successful sur- result in gery. This blood eventually is cleared out the same clearer way it got into the eye. Another cause of (gener- vision ally temporary) fluctuations in vision is surgically for some induced astigmatism from the suture used to close patients. the surgical incision. This almost always resolves by a month or so after surgery Once the eye is fully © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 10. 10 Will Canaloplasty cure my who undergo Canaloplasty have lower IOPs after surgery, but on average, they are able to stop just 1 glaucoma? No. To date there is no cure for glaucoma. The best any under two medications. What does “just under two” mean? Well, some people are able to stop one 5 treatment can do is to halt (or slow) the progression of this disease. The closer the IOP to 8mmHg, the drop, some two, others none and some are even better (below that and the eye can lose vision from able to stop all of their drops. How many you will 10 the pressure being too low). Studies have shown be able to stop if you have Canaloplasty cannot be that for most glaucoma patients an IOP of less than predicted, though it’s likely that you will be able to 15 15mmHg can be protective (a goal often achieved stop at least one of them if you are on multiple with Canaloplasty). Some forms of glaucoma (such drops. 21 12 as advanced, low tension, or normal tension glau- coma) require IOPs of less than 12mmHg in order How long will my IOP stay Last to avoid loss of vision. Only your eye surgeon can controlled with Canalo- determine what your eye’s goal should be. plasty? Because Canaloplasty has 11 only been FDA approved since 2008, we only have Will I be able to stop using three-year results. There is no reason, however, to glaucoma drops after Cana- believe that the surgery will “stop working.” In a loplasty? Possibly. Remember that study that looked at the long-term (7 year) results the primary objective of any glaucoma surgery (in- of combined cataract surgery and viscocanalosto- cluding Canaloplasty) is to lower your IOP into a my (the less effective precursor to Canaloplasty), safer range and protect you from further loss of IOP was reduced by over 33% (on average) at the vision. A secondary goal would be to reduce (or last documented visit. We can reasonably expect even eliminate) the use of glaucoma drops. Studies the long-term results of Canaloplasty and Phaco- have shown Canaloplasty to be effective at achiev- canaloplasty to be even better than those published ing both of these goals. Not only do most people for viscocanalostomy and Phacoviscocanalostomy. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 11. 13 What if Canaloplasty doesn’t surgery (and at least for a few days, but sometimes up to weeks after) your vision will be blurry in the 1 work? Can I still have tradi- eye that had canaloplasty. Therefore, any activities tional glaucoma surgery af- 5 that require good binocular vision (such as working ter Canaloplasty? Yes. Having Canaloplasty with heavy machinery) should be avoided until the does not affect your abil- vision improves. Addition- 10 ity to have other types of ally, it is generally a good glaucoma surgery at a later idea to keep the eye clean 15 date as long as your Ca- and dry (no gardening or naloplasty surgeon oper- swimming) for at least a 21 ates in one of the superior few weeks. Once the inci- “quadrants” of the eye. sion has healed over (about Last Some Canaloplasty sur- a month after surgery) it is geons, however, operate generally OK to resume all at what is called the 12:00 of your usual activities. position. This approach can make it difficult (but Contrast this with tradi- not impossible) for a sur- tional glacuoma surgery geon to perform tradition- (trabeculectomy) which al glaucoma surgery at a later date. does limit your activities for the rest of your life. 14 Because of the fragile nature of a bleb after trab- I’m a very active person. eculectomy (and the risk of rupture and/or infec- Will having Canaloplasty tion), once someone has had trabeculectomy sur- force me to limit my activities? gery s/he cannot participate in most water sports The answer to this question depends on what time, without high-quality protective eyewear. after surgery, you are referring. Immediately after © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 12. 15 I wear soft contact lenses. Can get intraocular pressures (IOPs) under 12mmHg. I continue to wear them after However, a recent head-to-head study comparing 1 one year results of Canaloplasty vs. trabeculectomy Canaloplasty? Yes, but you may showed no significant difference in average IOP 5 have to wait until the eye is healed from surgery. between the two surgeries. Granted, average IOP How soon you may restart use of contact lenses does not address the issue of the lowest IOP achiev- 10 will be up to your surgeon. Additionally, it may be able. Nevertheless, some of my own patients who necessary to get fitted for new contact lenses after have had Canaloplasty now have pressures between Canaloplasty as the surgery can sometimes change 8-10mmHg. This is by no means the average result, 15 your refractive error. but does speak to the issue of whether it is possible for Canaloplasty to lower the IOP below 10mmHg. 21 Contrast this with traditional glacuoma surgery 17 (trabeculectomy). Because of the fragile nature of Last a bleb after trabeculectomy (and the risk of rup- Is Canaloplasty really safer ture and/or infection), once someone has had trab- than traditional glaucoma sur- eculectomy surgery s/he cannot wear soft contact gery (trabeculectomy)? Yes. A lenses after surgery for as long as the bleb is func- recent study compared one year results of Cana- tioning. Hard contact lenses, however, are gener- loplasty vs. trabeculectomy. Although there was no ally OK to wear even with trabeculectomy (though significant difference in the final intraocular pres- a refitting may be needed after surgery). sures (IOPs) between the two surgeries (meaning both surgeries were equally good at lowering IOP), two differences were noted: (1) Canaloplasty patients 16 I’ve heard that Canaloplasty experienced fewer side effects and complications compared to those who had trabeculectomy; and (2) is not as effective as more the patients who had Canaloplasty had better vision traditional glaucoma surgery than those patients who had trabeculectomy. (trabeculectomy). Is this true? No, although this is widely believed by many surgeons who do not perform Canaloplasty. It has generally been Non-Penetrating Schlemm’s Canaloplasty versus Trab- eculectomy: A Head-to-Head Comparison. Tam D, Calafati J, thought that trabeculectomy is the only way to Ahmed I. [Submitted for publication, December 2009]. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 13. RISKS 1 5 Canaloplasty 10 15 21 18 What are Last 1. Bleeding in the eye. Almost 30% of people the Risks of who have Canaloplasty have some bleeding in the Canaloplasty? front of the eye. However, as mentioned earlier, Although it is true that there are this bleeding (called a hyphema or microhyphema) fewer risks with Canaloplasty than is pretty much to be expected (and may actually be there are with traditional glaucoma desired ). This resolves with time and rarely causes surgery (trabeculectomy), it is not any permanent reduction in vision. without risk. All surgeries (there are no exceptions) have risks associated with them. 2. Intraocular pressure “spikes” during the heal- The important thing to consider when faced with ing period after surgery. About 5% (one in twenty) the need for surgery is the relative risk of the pro- people will have a short period after surgery when cedure compared to going without the procedure. Canaloplasty and Transient Anterior Chamber If your glaucoma is not under control then (given Haemorrhage: a Prognostic Factor? Koch J, Heiligenhaus enough time) you will lose vision. Glaucoma sur- A, Heinz C. Klinische Monatsblätter für Augenheilkunde geries offer a method of preventing that loss of (Clinical Journal of Ophthalmology) 2010 Nov 16. (online vision. The most commonly encountered risks of ahead of print). Canaloplasty are: © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 14. the IOP is actually higher than it was before sur- ways resolve on their own. If it is not spontane- gery. This almost always resolves. ously improving, it is generally possible for your 1 surgeon to inject a gas bubble in your eye to press 3. The formation of a bleb (blister) on the sur- this membrane back against the cornea. 5 face of the eye in the area of the incision (6%). It is worth noting that with trabeculectomy, the for- 5. The need to perform traditional glaucoma 10 mation of a stable bleb is necessary for success, surgery (4%). Less than one in twenty Canalo- while with Canaloplasty, it is considered to be an plasty surgeries “fail” and must be converted to 15 undesireable outcome, or “risk.” These blebs rare- either trabeculectomy or a “shunt.” This may be ly limit the effectiveness of Canaloplasty. Howev- done either at the time of initial surgery or at a 21 er, blebs can be associated with Tear Dysfunctional later date. Your surgeon would make this decision Syndrome (Dry Eye Syndrome) and could limit as clinically appropriate. Last your ability to participate in certain activities (such as certain water sports). 6. Hypotony (IOP too low). “Too low?” you may be wondering, “I thought the problem was that 4. Descemet’s Membrane Separation, or De- the pressure was too high?” Well, if the IOP drops tachment (3%). In order to open Schlemm’s canal, below 5mmHg (millimeters of Mercury) and stays a gel-like substance (called a viscoelastic) is injected there, vision can be lost from a condition known as into the canal. If the canal is particularly “tight” “hypotony maculopathy.” Fortunately, this condi- it is possible for the get to follow the path of least tion is pretty rare with Canaloplasty (only one per- resistance and dissect beneath Descement’s Mem- son in 200 would be expected to have prolonged brane (the thin film on the back of the cornea). If hypotony). Compare this to trabeculectomy in this happens, the vision could be affected. How- which at least 1 out of every 10 people is likely to ever, with time (weeks to months) these almost al- experience hypotony. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 15. 7. Infection. To date, vision-threatening infec- als used to make the intraocular lenses (IOLs) in tion of the eye (called “endophthalmitis”) has not modern cataract surgery. It is very unlikely that 1 been documented with Canaloplasty. In theory, this suture would ever erode into or through the however, anytime an incision is made in the eye, an eye wall as it is securely threaded through Sch- 5 infection could be possible. So, although the risk lemm’s canal. In the few reported cases where the seems to be less than 1 in 1,000, it’s probably not suture has eroded into the anterior chamber it sel- 10 zero. Compare this to trabeculectomy which car- dom causes any problem. 15 20 ries up to a 5% chance per year of developing an infection called “blebitis” that (if not caught early What is the big and treated) can result in endophthalmitis and loss deal about a 21 of vision. bleb, anyway? With traditional glaucoma sur- Last In summary, although not without risk, Canalo- gery (trabeculectomy), a blis- plasty is associated with significantly fewer risks ter-like fluid collection (called a (both in number and severity) than traditional glau- “bleb”) must be present on the coma surgeries such as trabeculectomy surface of the eye for the surgery 19 to work. Aqueous fluid (the fluid I’m afraid of having some- inside the eye) flows through the fistula into this thing placed in my eye. What bleb where it then finds its way out of the eye. If are the risks of the stent? Al- this bleb scars down, the the surgery fails and the though this is an understandable concern, the only intraocular pressure (IOP) goes back up potential- thing left in the eye after Canaloplasty is a suture. ly causing a further loss of vision from glaucoma. The material used in this suture (polypropylene) has Unfortunately, the body wants to scar down the been used in eye surgery for decades and has a very bleb as part of the natural healing response. In good safety record. In fact, this material has been order to prevent this from happening most modern used in the eye far longer than most of the materi- trabeculectomy surgeons use a chemical called an © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 16. 1 “antimetabolite” to preserve the bleb. The most infection of the inside of the eye (endophthalmitis, 5 commonly used antimetabolite (Mitomycin-C, or up to 1% per year) if not successfully treated. En- MMC) causes permanent damage to the eye tissue dophthalmitis often leads to severe loss of vision in the area of the surgery. 10 or blindness. This risk continues for the life of the patient unless the bleb scars down (fails). The tissue exposed to MMC is very fragile and does 15 not heal well. Fluid in the bleb exerts pressure Canaloplasty is a “blebless” (or bleb-free) pro- which can result in what is called a “high bleb.” cedure. With Canaloplasty no fistuas are created 21 This is essentially a thin bubble-shaped bleb. These and there is no need to modify the natural healing can cause (or may exacerbate) Tear Dysfunctional of the eye. Without a bleb, there is no worsening Last Syndrome resulting in chronic irritation, tearing, of Tear Dysfunctional Syndrome or risk of blebi- and blurred vision. Because the wall of the bleb is tis. Occasionally (about 6% of the time), a bleb will so thin any trauma to the eye can rupture it. Since spontaneously form with Canaloplasty. However, it does not heal well any damage to the bleb may because most Canaloplasty surgeons do not use require surgical revision. MMC, the bleb is usually “shallow” and unlikely to result in Tear Dysfunctional Syndrom or blebitis. Finally, and most concerning, is that when MMC is used during trabeculectomy, there is up to a 5% risk per year of bleb leak which can progress to Greenfield DS, Suñer IJ, Miller MP, Kangas TA, Palmberg PF, Flynn HW Jr. Endophthalmitis after filtering surgery with mitomycin. Arch Ophthalmol 1996;114:943- 949. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 17. Surgeons References 1 Canaloplasty 5 10 15 21 Last 21 Are all Canaloplasty surgeons Glaucoma Specialists? No. For example, Dr. Richardson is not a glaucoma specialist. A glaucoma specialist is someone who spends one to two additional years after resi- dency learning how to deal with advanced and unusual forms of glaucoma. Because Canaloplasty can most effectively treat ear- lier (less advanced) forms of the more common types of open angle glaucoma, it is often performed by general ophthalmolo- gists and/or cataract surgeons. Indeed, it is particularly effective when done at the same time as cataract surgery - in which case it is called “phacocanaloplasty.” © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 18. 22 What training is required to become an Interventional Ophthalmologist (Canalo- plasty Surgeon)? Interventional Ophthalmolo- 23 Where can I find a Canaloplasty surgeon near me? • Visit the iScience website. This site will provide a list of Canaloplasty surgeons near you. 1 5 gists must first complete their training as EyeMDs 10 24 (completion of a bachelor’s degree followed by four years of medical school, one year of intern- How much does Canaloplasty 15 ship, and three years of residency training in eye cost? The amount charged for ca- diseases and surgery). Once proficient as an eye naloplasty varies by surgeon and sur- 21 surgeon, an ophthalmologist can request to be gery center. If you do not have insurance, the total trained in the technique of Canaloplasty. Doctors cost for canaloplasty can range from $5,000 to up- Last are required to complete a “wet-lab” (practice on wards of $10,000 per eye. Fortunately, Medicare cadaver eyes) prior to performing Canaloplasty sur- and many insurances pay for Canaloplasty when gery on humans. Then, the first 10 surgical treatment of glaucoma is indicated. Even surgeries are conducted under the if you do not have insurance, however, Canalo- direct monitoring of a Clinical Spe- plasty can pay for itself over time simply by saving cialist. Only a fraction of surgeons you $1,000s per year in the cost of glaucoma drops who start the Canalo- that may no longer be necessary after this surgery. plasty training complete the monitoring require- http://canaloplasty.com/iscience/find_a_physician.php ments and go on to be- come Canaloplasty sur- geons. © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 19. 25 Where can I learn more about Canaloplasty? Below are some additional resources that could help you to decide if Canaloplasty is right for you: 1 5 1. Canaloplasty.com - Created by iScience, the manufacturer of the catheter used in Cana- 10 loplasty. This is where you would go to find a Canaloplasty surgeon near you. 15 2. YouTube.com - If you want to see what this surgery actually looks like (and aren’t too squeamish). 21 3. Google Alerts - You will need a Google account for this. Set up an alert with the word Last “canaloplasty” in it and Google will send you an email whenever it finds a new article, post, or video about Canaloplasty. Find out if you 4. Find a Canalplasty sur- geon and schedule a consul- or your loved one tation - There is no better way qualifies for to find out if Canaloplasty is Canaloplasty ! right for you than to have your eye evaluated by a surgeon cer- tified to perform Canaloplasty. Evaluation Form http://new-glaucoma-treatments.com/canaloplasty-evaluation/ © 2011 New-Glaucoma-Treatments.com | call 626.289.2223 | CA 91776
  • 20. Thank You for Reading! I hope you learned something of value. Dr. David Richardson has performed thousands of eye surgeries using the most advanced techniques. He is trusted not only by thousands of patients, but also by oth- er medical professionals. In a series of surveys, medical professionals were asked a simple question: “If you needed medical care, which doc- tor would you choose?” Based on the results of these sur- veys, Dr. Richardson was named a “Super Doctor” by his peers in the Los Angeles Magazine in 2010 2011. In a similar survey conducted by Pasadena Magazine, Dr. Ri- http://new-glaucoma-treatments.com/contact-form/ chardson was also voted as a “Top Doc” for the past 3 consecutive years (2008, 2009 and 2010). Actions, though, speak louder than words - Dr. Richardson is the personal eye surgeon for many of the Contact most respected doctors in the San Gabriel valley. Dr. David Richardson is among a select Dr. Richardson group of ophthalmologists in Southern California offering Canaloplasty as a treatment option for his glaucoma patients. For more canaloplasty information by Dr. David Rich- ardson, please visit New-Glaucoma-Treatments.com