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Napa County
2013 Medical Health
Tabletop Exercise
October 28, 2013
10:00 AM – 2:00 PM

1
Welcome and Introductions
The 2013 Statewide Medical and Health
Exercise is sponsored by:
• California Emergency Medical Services Authority
• California Department of Public Health

In collaboration with:
•
•
•
•
•

California Hospital Association
California Association of Health Facilities
California Primary Care Association
California Emergency Management
Response partners representing local health
departments, emergency medical services, public
safety and healthcare facilities
2
Welcome and Introductions
 Introduction of Exercise Planners and Facilitators
 Housekeeping Issues
 Agenda Review

3
Exercise Purpose
To evaluate current response concepts, plans,
and capabilities related to a medical surge of
patients from a foodborne illness outbreak in the
local community.
The exercise will focus on the coordination of
surveillance activities and health system
capabilities anticipated when managing a medical
surge among community healthcare partners.

4
Exercise Target Capabilities

 Public Health Epidemiology & Surveillance
 Emergency Public Information & Communications
 Emergency Operations Center Management &
Medical Surge

5
Tabletop Exercise Objectives
Evaluate ability to:
 Activate surge plans
 Implement the Incident Command System
 Request, distribute, track and return resources
in accordance with the California Public Health
Emergency Operations Manual (EOM)

 Coordinate risk communication

6
Tabletop Exercise Objectives
Evaluate ability to:
 Issue public information notifications
 Conduct surveillance and epidemiological
investigations
 Implement necessary control measures to stop
further cases of illness or disease

7
Tabletop Exercise Scenario
Scenario:
 Napa residents are presenting to healthcare
providers with abdominal pain and bloody
diarrhea in above average numbers
 Some patients are needing hospital and ICU
admission
 A foodborne disease is suspected

8
Subject Matter Experts
• Dr. Jennifer Henn, Epidemiologist
• Napa County Public Health

• Dr. Karen Smith, Health Officer
• Napa County Public Health

• Jahniah McGill, Registered Environmental Health
Specialist
• Environmental Health, Napa County

9
EPIDEMIOLOGY
Dr. Jennifer Henn
Epidemiologist
Napa County Public Health

10
EPIDEMIOLOGY OF A
FOODBORNE ILLNESS

11
FOODBORNE ILLNESSES
• Caused by ingestion of contaminated food

• Can also be spread via other modes
• Gastrointestinal tract symptoms
 Nausea & vomiting
 Diarrhea
 Abdominal pain

• Nonspecific symptoms outside the G.I. tract
• Children under 5, older adults and medically fragile
are most vulnerable

12
12
FOODBORNE ILLNESSES
An estimated 1 in 6 suffer from foodborne illnesses
annually leading to an estimated:
 48 million cases
 128,000 hospitalizations
 3,000 deaths
 $35 billion in medical costs & lost productivity

>1,000 outbreaks detected annually

(Painter JA, Hoekstra RM, Ayers T, Tauxe RV, Braden CR, Angulo FJ, et al. Attribution of foodborne
illnesses, hospitalizations, and deaths to food commodities by using outbreak data, United States, 1998–
2008. Emerg Infect Dis [Internet]. 2013.)

13
13
DAILY DOUBLE
What foodborne disease do these foods have in
common?
•
•
•
•
•
•

Raw sprouts
Pizza
Cookie dough
Fresh spinach
Ground beef patties
Romaine lettuce

14

14

14
SHIGA TOXIN PRODUCING E. COLI

15
E. COLI O157:H7
 First recognized as pathogen in 1982

 First outbreak traced to hamburgers
 USDA banned sale of raw meat containing E. coli
O157:H7 in 1994

 Many outbreaks now linked to contaminated raw
vegetables (e.g., sprouts, leafy greens) and other
contaminated ready to eat foods

16
STEC OUTBREAKS
2012
Multistate Outbreak of Shiga Toxin-producing
Escherichia coli O157:H7 Infections Linked to Organic
Spinach and Spring Mix Blend
Multistate Outbreak of Shiga Toxin-producing
Escherichia coli O145 Infections
Source not identified
Multistate Outbreak of Shiga toxin-producing
Escherichia coli O26 Infections Linked to Raw Clover
Sprouts at Jimmy John's Restaurants

17
STEC OUTBREAKS
2011
Multistate Outbreak of E. coli O157:H7 Infections
Linked to Romaine Lettuce
Outbreak of Shiga toxin-producing E. coli O104 (STEC
O104:H4) Infections Associated with Travel to
Germany (and consumption of raw sprouts)
Multistate Outbreak of E. coli O157:H7 Infections
Associated with Lebanon Bologna
Multistate Outbreak of E. coli O157:H7 Infections
Associated with In-shell Hazelnuts

18
E. COLI CONTAMINATION
AN EXAMPLE
 Multistate E. coli O157:H7 outbreak linked to baby
spinach in 2006 (205 cases, 102 hospitalizations, 3
deaths)
 Outbreak strain isolated from both cattle and feral swine
feces near spinach field
 Spinach from 1 field with E. coli
contamination mixed with spinach
and lettuce from other farms at
central processing plants

19
CONTAMINATION
AN EXAMPLE
Feral pigs
had access
to both cattle
and spinach
fields

Surface water
used for
irrigation
potentially
contaminated
with E. coli

20
E. COLI AND MEDICAL SURGE
AN EXAMPLE
 Outbreak of E. coli O104:H4 in 2011
– 3,816 cases in Germany; 54 deaths
– 845 (22%) involved Hemolytic Uremic Syndrome (HUS)

 Hospitals in most affected areas of Germany experienced
large influx of patients with HUS and other complications
due to E. coli infection
– Doubled number of staff
– Tripled machines for dialysis and plasma exchange

21
E. COLI AND MEDICAL SURGE
AN EXAMPLE
Video news clip:

http://www.bbc.co.uk/news/world-13696131

22
SHIGA TOXIN PRODUCING E. COLI
 Common reservoirs = cattle and other ruminants
 Vehicles in past outbreaks = ground beef, petting zoos, raw
vegetables and fruit, unpasteurized apple cider, water, etc.
 Growth requirements = facultative anaerobe, nonsporulating bacterium

23
E. COLI - EPIDEMIOLOGY
 Mode of Transmission
 Ingestion of food contaminated by traces of feces or direct
contact with animals and their environment

 Incubation Period
 Range from 2-10 days after exposure; median 3-4 days

 Period of Communicability
 When the bacteria is being excreted
 1 week or less (adults) or up to 3 weeks (children)

24
24
SHIGA TOXIN PRODUCING

E. COLI (STEC)
 Some E. coli bacteria produce shiga toxin
 When shiga toxin enters the bloodstream it
can damage the red blood cells
 Severity of illness ranges from mild diarrhea
to life threatening HUS

25
25
CLINICAL SYMPTOMS AND
TREATMENT OF STEC
INFECTIONS
Dr. Karen Smith
Health Officer
Napa County Public Health

26
SYMPTOMS
Symptoms of E. coli infection:
 Watery and often bloody diarrhea
 Abdominal cramping
 Abdominal pain
 Little or no fever
Most people will recover within 5 to 10 days

27
HEMOLYTIC UREMIC SYNDROME
(HUS)
 Life threatening condition that often
requires ICU treatment
 Triad of hemolytic anemia,
thrombocytopenia, and acute renal failure
 Often requires blood transfusions and
dialysis during acute phase

28
HEMOLYTIC UREMIC SYNDROME
(HUS)
 On average, HUS occurs in ~6% of E. coli
patients
 Case fatality rate of 3-5%
 Most cases of HUS occur in children under 5
 Use of antibiotics and anti-diarrheal
medication to treat E. coli infection increases
risk of HUS
29
DIALYSIS
 Average length of dialysis for patients with HUS due
to E. coli infection is 5-7 days (but can vary widely)
 Peritoneal dialysis widely used for pediatric patients
 Hemodialysis also suitable for children - may be
preferable in patients with severe abdominal pain

30
MANAGEMENT OF HUS
Successful management of HUS includes:

• Fluid therapy
• Management of acute renal failure
- ~50% of HUS patients require dialysis

• Blood and/or plasma transfusion
- Most children require packed RBC transfusion

• Management of hypertension
• Nutritional support and pain management

31
STEC – SPECIAL CONSIDERATIONS
 Most E. coli related HUS cases seen in children
< 5, but elderly and immunocompromised are
also at increased risk for HUS
 Elderly patients at higher risk for E. coli blood
stream infection (bacteremia) and may develop
additional complications due to presence of other
illnesses

32
FOODBORNE
OUTBREAK RESPONSE
Dr. Jennifer Henn
Epidemiologist
Napa County Public Health

33
OUTBREAK INVESTIGATION GOALS
 Identify all cases
 Find a common exposure
 Determine cause

 Stop the exposure
 Prevent future cases

 Notify providers
 Inform the public
34
34
A COORDINATED RESPONSE
Public Health

Foodborne Illness
Response Team

Laboratory

Environmental
35
Health
35
PUBLIC HEALTH RESPONSE ROLE
Public Health Nurses and Disease Investigators
• Interview patients
• Collect clinical specimens from patients
• Administer questionnaires for epidemiologic
studies
• Advise patients on how to prevent spread of
illness
• Provide public health education & guidance
(i.e., health advisories and health alerts)
36
36
PUBLIC HEALTH RESPONSE ROLE
Epidemiologists
• Analyze data from pathogen-specific
surveillance and identify clusters/outbreaks
• Characterize cases by time, place, and person
• Plan epidemiologic studies
• Interview cases and healthy controls
• Analyze and interprets results of epidemiologic
studies
37
PUBLIC HEALTH LABORATORY
RESPONSE ROLE
Public Health Laboratory staff
• Analyze clinical, food, and environmental
specimens
• Interpret test results and “fingerprint” strains
• Advise about tests and collection, handling,
storage, and transport of specimens
• Coordinate additional testing by partner labs

38
WHO ARE THE PUBLIC HEALTH
STATE AND FEDERAL PARTNERS?
• California Emerging Infections
Program (CEIP)
• California Department of Public
Health (CDPH)
• Centers for Disease Control and
Prevention (CDC)
39
39
E. COLI O157 CASE
CONFIRMATION PATHWAY

40
40
ENVIRONMENTAL
HEALTH RESPONSE
Jahniah McGill, MPH
Registered Environmental
Health Specialist
Napa County Environmental Health

41
HOW DOES ENVIRONMENTAL HEALTH BECOME
AWARE OF FOOD RELATED EVENTS?
Environmental Health
• Reporting Methods
−
−

Online complaint system
Telephone complaint

• Reporters of Illness
−
−
−

Consumer complaints
Food facility operators
Health and Human Services: Public Health

• State & Federal Partners
−
−
−

California Food & Drug Branch (CDPH)
US Food and Drug Administration (FDA)
US Department of Agriculture (USDA)
42
42
ENVIRONMENTAL HEALTH
RESPONSE ROLE
Environmental Health Inspectors focus on how the
food became contaminated:
• Receive and interpret foodborne illness complaints
• Investigate suspected food and/or food establishment
− Interview food workers and managers
− Examine food storage, handling, preparation, and
service
− Identify risk factors that resulted in food contamination
− Collect environmental and food samples
− Collect paperwork
43
43
ENVIRONMENTAL HEALTH
RESPONSE ROLE
Environmental Health Inspectors focus on how the
food became contaminated:
Implement control measures
• Employee education
• Disposal of contaminated food
• Impound
• Closure of premises
• Administrative hearing process
• Probationary period
44
44
ENVIRONMENTAL HEALTH
RESPONSE ROLE
Environmental Health Inspectors refer to the following
agencies:
• CDPH Food and Drug Branch (CDPH)
− Manufacturers, Processors, Wholesale
− Seafood and Shellfish
− Recall of Foods
• CA Department of Food and Agriculture (CDFA)
− All Meat and Dairy Products
• U.S. Food and Drug Administration (FDA)
− Interstate Manufactures, Processors, Wholesale
45
45
HOW DO YOU CONTACT
ENVIRONMENTAL HEALTH?
PBES: Environmental Health Division
Main Phone: (707) 253-4471 or (707) 253-4417
Main E-mail: Environmental@countyofnapa.org
County Website:
http://www.countyofnapa.org/PBES/Environmental/

46
46
Exercise Ground Rules
 Do not fight the scenario
 Assume the scenario is real and
may impact the jurisdiction and
the participants
 Participate in a collegial
manner: share policies,
plans and practices that
may benefit others

47
Exercise Ground Rules
 Be respectful: allow others
to speak and finish their
statements
 Follow communications
etiquette: turn off cell
phones, computers, and
any other electronic data
equipment

48
Tabletop Exercise
 The exercise consists of three modules plus an
addendum for planning the November 21, 2013
Functional Exercise
 Each module will identify the key issues followed
by questions for discussion
 Participants are encouraged to share their plans,
policies, strengths and gaps as identified in the
Organizational Self Assessments

49
Scenario
On November 18, 2013, healthcare providers at
community health centers, private physician’s offices
and local emergency departments began seeing
previously healthy patients with complaints of
abdominal pain throughout Napa County.

50
Scenario (Continued)
Within one day, 40 cases of bloody diarrhea had
been reported by 10 healthcare providers at
community health centers, private physician’s offices
and local emergency departments in the county.

Two days after the first reports of abdominal pain and
bloody diarrhea, 4 patients (of which, 2 are pediatric)
were admitted to the Intensive Care Unit with
symptoms of decreased urine output, lethargy and
persistent bloody diarrhea. These patients were
diagnosed with hemolytic uremic syndrome. Cases
presenting similar symptoms continue to be reported
throughout the county.
51
Scenario (Continued)
Five days after the first
reported case, 225 patients
(approximately 10% with
HUS) have been identified
with similar presenting
symptoms at local hospitals,
community health centers
and private physician
practices.

52
Scenario (Continued)
Healthcare facility staff has requested guidance
from the local Public Health Laboratory on
appropriate protocols for specimen collection
and laboratory techniques to confirm the
diagnosis.
Healthcare facilities are requesting guidance on
necessary levels of isolation and personal
protective equipment requirements for staff.

53
Module 1: Public Health Surveillance
and Epidemiological Investigation
Key Issues:

 Surveillance and epidemiological investigation
coordinated with the healthcare partners
 Implement control measures

54
Questions for Discussion
1. When and how would your organization/agency be
made aware of an increase in Shiga Toxin-producing
E. coli isolates within your jurisdiction?
a. Are there multiple modes of communication for this kind of
information?

2. What would prompt an investigation, and who would
undertake the investigation and analysis if an
outbreak were to occur in your jurisdiction?

55
Questions for Discussion
3. How does your organization/agency collaborate with
the laboratories?
a. How is testing prioritized?

4. How are control measures issued by Public Health,
Environmental Health, healthcare facilities?
a. How are the control measures implemented by each?

56
LUNCH
BREAK
57
Module 2: Emergency Public
Information and Communications
Key Issues:

 Alerting and notification of personnel
 Internal and external communications
 Risk communication messaging

58
Questions for Discussion
1. What mechanisms and/or technologies are in place
to alert and notify your staff of activation of your
facility’s emergency operations plan?
a. How do you notify staff of activation?
b. Who is responsible to do that?
c.

How often do you test this system?

d. Has this system been used in a real event?

e. Who else do you notify of activation?
f.

How does that occur?

59
Questions for Discussion
2. How do you share information with Public Health?
a. What information do you share?
b. What information do you expect from Public Health?
c.

How do you communicate your facility status (and bed
availability) to the local medical health system?

d. How does this information get to the state?

60
Questions for Discussion
3. What is your risk communication plan to notify staff,
patients, clients and/or stakeholders of a foodborne
illness outbreak?
a. Who approves the information to be shared?
b. What communication methods are used?
c.

How does your organization participate in a Joint
Information System (JIS)?

d. What would warrant opening a Joint Information Center

(JIC)?
e. How do you manage inquiries from the media,
stakeholders, and the general public?
61
Scenario (Continued)
Ambulance companies are reporting an increase in
call volume and extended delays in offloading
patients at local emergency departments.
Hospitals are experiencing continuing surge with
increasing emergency department wait times.
The initial epidemiologic investigation has not
revealed a consistent pattern of age, race,
occupation, geographic distribution or previous
symptomatology among patients which might
indicate a source of the offending agent.

62
Module 3: Emergency Operations Center
Management and Medical Surge
Key Issues:

 Response is coordinated through the use of Incident
Command System principles and Command
Centers/Emergency Operations Centers
 Incident Action Plans are developed to guide and
document the response and recovery phases
 Activation of Surge Plans
 Request and/or response to resource requests
63
Questions for Discussion
1. How do you plan for an influx of patients including the
access and functional needs population?
a. What types of services can be altered, postponed or relocated to
other sites?
b. Have clinical providers been active in the decision making for
alteration of services?

64
Questions for Discussion
2. Which partner organizations can assist in providing
services that you must alter or suspend due to a medical
surge?
a. Do you have Memoranda of Understanding signed with these
partner organizations?

3. How do you request, respond to, distribute, track and/or
return resources in accordance with the California Public
Health and Medical Emergency Operations Manual?

65
Resource Requesting

Dr. Karen Smith
Napa County Public Health Officer

66
Medical & Public Health Resources
• Personnel

• Services
• Supplies and Equipment
• Transportation
• Facilities

68
Healthcare Facility Managers
How to Obtain Resources:
• Communication through accepted local protocols
• Communicating resource arrangements
minimized duplication of efforts

69
HC Facility Resource Utilization
• Determine if current resources will meet the anticipated
needs
• Prioritize/conserve what’s available
• Contact suppliers/contractors
• Implement existing agreements

• Request help from the HHSA/DOC - MHOAC

70
HHSA Department Operations
Center (DOC)
DOC
Director
PIO

Health
Officer

Safety
Officer

Liaison
Officer
Operations
Section

Planning
Section

Logistics
Section

Finance
Section

Medical
Branch
Health
Branch
72
DOC Medical & Health Branch
Operations
Section

Medical
Branch

Health Branch

EMS/Transport
Patient
Tracking

Communicable
Disease

Healthcare
Facilities
Coordination

Laboratory

Alternate Care
Site

Activate
branches as
needed

Mass
Prophylaxis
73
CA Mutual Aid System
• CA disaster & Civil Defense Master Mutual Aid
Agreement (MAA)
• Discipline-Specific Mutual Aid Agreements
• Health Care Facilities Mutual Aid or Mutual
Assistance Agreements

75
CA Mutual Aid Regions
3

1

2

4

5
6

1

76
Regional Disaster Medical & Health
Coordinator/Specialist (RDMC/S)
REOC

Medical Health Branch
RDMHC/S Program

OA EOC

Med. Health Branch
MHOAC Program

OA EOC

Med. Health Branch
MHOAC Program

OA EOC

Med. Health Branch
MHOAC Program

Affected Local Jurisdictions
77
Who You Gonna Call?

Public Health/
HHSA!!!
Public Health/HHSA DOC is your
gateway to CA’s mutual aid…

79
Tabletop Conclusion

You Survived!
80
HOT WASH

81
Planning for the November
Functional Exercise
The scenario will be a medical
surge due to foodborne illness.

Customization of the exercise
allows incorporating other
objectives as needed.
Examples include issues
identified in past exercises,
new training or equipment, or
new policies and procedures.
82
November Exercise
Issues for Consideration
Exercise Level of Play:
 What level of exercise play do the
organizations/agencies represented today anticipate
for the November 21, 2013 exercise?
 Examples include communications drill, functional and
full scale exercises, level of play may include use of
simulated patients, movement of patients to healthcare
facilities, activation of the joint information center,
provision of mutual aid, etc.
 Will your organization/agency activate its Command
Center/Emergency Operations Center?
83
Role of State Agencies
On November 21, 2013, the California Department of
Public Health and the California Emergency Medical
Services Authority will open the Medical and Health
Coordination Center (Formerly the Joint Emergency
Operations Center).
The California Emergency Management Agency is
anticipated to participate by opening the State Operations
Center and the Regional Emergency Operations Centers to
support local and regional exercise play.
This will provide the opportunity for local participants to
request additional resources, submit and receive situation
status reports and respond to California Health Alert
Network (or other notification systems) messages and
receive further direction.
84
Evaluations

Please
complete

your
Evaluation…
85
Thank You
For Your Participation
Additional materials may be found on:

California Statewide Medical and Health
Training and Exercise Program website:

86

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Napa Foodborne Illness Tabletop Exercise 2013

  • 1. Napa County 2013 Medical Health Tabletop Exercise October 28, 2013 10:00 AM – 2:00 PM 1
  • 2. Welcome and Introductions The 2013 Statewide Medical and Health Exercise is sponsored by: • California Emergency Medical Services Authority • California Department of Public Health In collaboration with: • • • • • California Hospital Association California Association of Health Facilities California Primary Care Association California Emergency Management Response partners representing local health departments, emergency medical services, public safety and healthcare facilities 2
  • 3. Welcome and Introductions  Introduction of Exercise Planners and Facilitators  Housekeeping Issues  Agenda Review 3
  • 4. Exercise Purpose To evaluate current response concepts, plans, and capabilities related to a medical surge of patients from a foodborne illness outbreak in the local community. The exercise will focus on the coordination of surveillance activities and health system capabilities anticipated when managing a medical surge among community healthcare partners. 4
  • 5. Exercise Target Capabilities  Public Health Epidemiology & Surveillance  Emergency Public Information & Communications  Emergency Operations Center Management & Medical Surge 5
  • 6. Tabletop Exercise Objectives Evaluate ability to:  Activate surge plans  Implement the Incident Command System  Request, distribute, track and return resources in accordance with the California Public Health Emergency Operations Manual (EOM)  Coordinate risk communication 6
  • 7. Tabletop Exercise Objectives Evaluate ability to:  Issue public information notifications  Conduct surveillance and epidemiological investigations  Implement necessary control measures to stop further cases of illness or disease 7
  • 8. Tabletop Exercise Scenario Scenario:  Napa residents are presenting to healthcare providers with abdominal pain and bloody diarrhea in above average numbers  Some patients are needing hospital and ICU admission  A foodborne disease is suspected 8
  • 9. Subject Matter Experts • Dr. Jennifer Henn, Epidemiologist • Napa County Public Health • Dr. Karen Smith, Health Officer • Napa County Public Health • Jahniah McGill, Registered Environmental Health Specialist • Environmental Health, Napa County 9
  • 12. FOODBORNE ILLNESSES • Caused by ingestion of contaminated food • Can also be spread via other modes • Gastrointestinal tract symptoms  Nausea & vomiting  Diarrhea  Abdominal pain • Nonspecific symptoms outside the G.I. tract • Children under 5, older adults and medically fragile are most vulnerable 12 12
  • 13. FOODBORNE ILLNESSES An estimated 1 in 6 suffer from foodborne illnesses annually leading to an estimated:  48 million cases  128,000 hospitalizations  3,000 deaths  $35 billion in medical costs & lost productivity >1,000 outbreaks detected annually (Painter JA, Hoekstra RM, Ayers T, Tauxe RV, Braden CR, Angulo FJ, et al. Attribution of foodborne illnesses, hospitalizations, and deaths to food commodities by using outbreak data, United States, 1998– 2008. Emerg Infect Dis [Internet]. 2013.) 13 13
  • 14. DAILY DOUBLE What foodborne disease do these foods have in common? • • • • • • Raw sprouts Pizza Cookie dough Fresh spinach Ground beef patties Romaine lettuce 14 14 14
  • 15. SHIGA TOXIN PRODUCING E. COLI 15
  • 16. E. COLI O157:H7  First recognized as pathogen in 1982  First outbreak traced to hamburgers  USDA banned sale of raw meat containing E. coli O157:H7 in 1994  Many outbreaks now linked to contaminated raw vegetables (e.g., sprouts, leafy greens) and other contaminated ready to eat foods 16
  • 17. STEC OUTBREAKS 2012 Multistate Outbreak of Shiga Toxin-producing Escherichia coli O157:H7 Infections Linked to Organic Spinach and Spring Mix Blend Multistate Outbreak of Shiga Toxin-producing Escherichia coli O145 Infections Source not identified Multistate Outbreak of Shiga toxin-producing Escherichia coli O26 Infections Linked to Raw Clover Sprouts at Jimmy John's Restaurants 17
  • 18. STEC OUTBREAKS 2011 Multistate Outbreak of E. coli O157:H7 Infections Linked to Romaine Lettuce Outbreak of Shiga toxin-producing E. coli O104 (STEC O104:H4) Infections Associated with Travel to Germany (and consumption of raw sprouts) Multistate Outbreak of E. coli O157:H7 Infections Associated with Lebanon Bologna Multistate Outbreak of E. coli O157:H7 Infections Associated with In-shell Hazelnuts 18
  • 19. E. COLI CONTAMINATION AN EXAMPLE  Multistate E. coli O157:H7 outbreak linked to baby spinach in 2006 (205 cases, 102 hospitalizations, 3 deaths)  Outbreak strain isolated from both cattle and feral swine feces near spinach field  Spinach from 1 field with E. coli contamination mixed with spinach and lettuce from other farms at central processing plants 19
  • 20. CONTAMINATION AN EXAMPLE Feral pigs had access to both cattle and spinach fields Surface water used for irrigation potentially contaminated with E. coli 20
  • 21. E. COLI AND MEDICAL SURGE AN EXAMPLE  Outbreak of E. coli O104:H4 in 2011 – 3,816 cases in Germany; 54 deaths – 845 (22%) involved Hemolytic Uremic Syndrome (HUS)  Hospitals in most affected areas of Germany experienced large influx of patients with HUS and other complications due to E. coli infection – Doubled number of staff – Tripled machines for dialysis and plasma exchange 21
  • 22. E. COLI AND MEDICAL SURGE AN EXAMPLE Video news clip: http://www.bbc.co.uk/news/world-13696131 22
  • 23. SHIGA TOXIN PRODUCING E. COLI  Common reservoirs = cattle and other ruminants  Vehicles in past outbreaks = ground beef, petting zoos, raw vegetables and fruit, unpasteurized apple cider, water, etc.  Growth requirements = facultative anaerobe, nonsporulating bacterium 23
  • 24. E. COLI - EPIDEMIOLOGY  Mode of Transmission  Ingestion of food contaminated by traces of feces or direct contact with animals and their environment  Incubation Period  Range from 2-10 days after exposure; median 3-4 days  Period of Communicability  When the bacteria is being excreted  1 week or less (adults) or up to 3 weeks (children) 24 24
  • 25. SHIGA TOXIN PRODUCING E. COLI (STEC)  Some E. coli bacteria produce shiga toxin  When shiga toxin enters the bloodstream it can damage the red blood cells  Severity of illness ranges from mild diarrhea to life threatening HUS 25 25
  • 26. CLINICAL SYMPTOMS AND TREATMENT OF STEC INFECTIONS Dr. Karen Smith Health Officer Napa County Public Health 26
  • 27. SYMPTOMS Symptoms of E. coli infection:  Watery and often bloody diarrhea  Abdominal cramping  Abdominal pain  Little or no fever Most people will recover within 5 to 10 days 27
  • 28. HEMOLYTIC UREMIC SYNDROME (HUS)  Life threatening condition that often requires ICU treatment  Triad of hemolytic anemia, thrombocytopenia, and acute renal failure  Often requires blood transfusions and dialysis during acute phase 28
  • 29. HEMOLYTIC UREMIC SYNDROME (HUS)  On average, HUS occurs in ~6% of E. coli patients  Case fatality rate of 3-5%  Most cases of HUS occur in children under 5  Use of antibiotics and anti-diarrheal medication to treat E. coli infection increases risk of HUS 29
  • 30. DIALYSIS  Average length of dialysis for patients with HUS due to E. coli infection is 5-7 days (but can vary widely)  Peritoneal dialysis widely used for pediatric patients  Hemodialysis also suitable for children - may be preferable in patients with severe abdominal pain 30
  • 31. MANAGEMENT OF HUS Successful management of HUS includes: • Fluid therapy • Management of acute renal failure - ~50% of HUS patients require dialysis • Blood and/or plasma transfusion - Most children require packed RBC transfusion • Management of hypertension • Nutritional support and pain management 31
  • 32. STEC – SPECIAL CONSIDERATIONS  Most E. coli related HUS cases seen in children < 5, but elderly and immunocompromised are also at increased risk for HUS  Elderly patients at higher risk for E. coli blood stream infection (bacteremia) and may develop additional complications due to presence of other illnesses 32
  • 33. FOODBORNE OUTBREAK RESPONSE Dr. Jennifer Henn Epidemiologist Napa County Public Health 33
  • 34. OUTBREAK INVESTIGATION GOALS  Identify all cases  Find a common exposure  Determine cause  Stop the exposure  Prevent future cases  Notify providers  Inform the public 34 34
  • 35. A COORDINATED RESPONSE Public Health Foodborne Illness Response Team Laboratory Environmental 35 Health 35
  • 36. PUBLIC HEALTH RESPONSE ROLE Public Health Nurses and Disease Investigators • Interview patients • Collect clinical specimens from patients • Administer questionnaires for epidemiologic studies • Advise patients on how to prevent spread of illness • Provide public health education & guidance (i.e., health advisories and health alerts) 36 36
  • 37. PUBLIC HEALTH RESPONSE ROLE Epidemiologists • Analyze data from pathogen-specific surveillance and identify clusters/outbreaks • Characterize cases by time, place, and person • Plan epidemiologic studies • Interview cases and healthy controls • Analyze and interprets results of epidemiologic studies 37
  • 38. PUBLIC HEALTH LABORATORY RESPONSE ROLE Public Health Laboratory staff • Analyze clinical, food, and environmental specimens • Interpret test results and “fingerprint” strains • Advise about tests and collection, handling, storage, and transport of specimens • Coordinate additional testing by partner labs 38
  • 39. WHO ARE THE PUBLIC HEALTH STATE AND FEDERAL PARTNERS? • California Emerging Infections Program (CEIP) • California Department of Public Health (CDPH) • Centers for Disease Control and Prevention (CDC) 39 39
  • 40. E. COLI O157 CASE CONFIRMATION PATHWAY 40 40
  • 41. ENVIRONMENTAL HEALTH RESPONSE Jahniah McGill, MPH Registered Environmental Health Specialist Napa County Environmental Health 41
  • 42. HOW DOES ENVIRONMENTAL HEALTH BECOME AWARE OF FOOD RELATED EVENTS? Environmental Health • Reporting Methods − − Online complaint system Telephone complaint • Reporters of Illness − − − Consumer complaints Food facility operators Health and Human Services: Public Health • State & Federal Partners − − − California Food & Drug Branch (CDPH) US Food and Drug Administration (FDA) US Department of Agriculture (USDA) 42 42
  • 43. ENVIRONMENTAL HEALTH RESPONSE ROLE Environmental Health Inspectors focus on how the food became contaminated: • Receive and interpret foodborne illness complaints • Investigate suspected food and/or food establishment − Interview food workers and managers − Examine food storage, handling, preparation, and service − Identify risk factors that resulted in food contamination − Collect environmental and food samples − Collect paperwork 43 43
  • 44. ENVIRONMENTAL HEALTH RESPONSE ROLE Environmental Health Inspectors focus on how the food became contaminated: Implement control measures • Employee education • Disposal of contaminated food • Impound • Closure of premises • Administrative hearing process • Probationary period 44 44
  • 45. ENVIRONMENTAL HEALTH RESPONSE ROLE Environmental Health Inspectors refer to the following agencies: • CDPH Food and Drug Branch (CDPH) − Manufacturers, Processors, Wholesale − Seafood and Shellfish − Recall of Foods • CA Department of Food and Agriculture (CDFA) − All Meat and Dairy Products • U.S. Food and Drug Administration (FDA) − Interstate Manufactures, Processors, Wholesale 45 45
  • 46. HOW DO YOU CONTACT ENVIRONMENTAL HEALTH? PBES: Environmental Health Division Main Phone: (707) 253-4471 or (707) 253-4417 Main E-mail: Environmental@countyofnapa.org County Website: http://www.countyofnapa.org/PBES/Environmental/ 46 46
  • 47. Exercise Ground Rules  Do not fight the scenario  Assume the scenario is real and may impact the jurisdiction and the participants  Participate in a collegial manner: share policies, plans and practices that may benefit others 47
  • 48. Exercise Ground Rules  Be respectful: allow others to speak and finish their statements  Follow communications etiquette: turn off cell phones, computers, and any other electronic data equipment 48
  • 49. Tabletop Exercise  The exercise consists of three modules plus an addendum for planning the November 21, 2013 Functional Exercise  Each module will identify the key issues followed by questions for discussion  Participants are encouraged to share their plans, policies, strengths and gaps as identified in the Organizational Self Assessments 49
  • 50. Scenario On November 18, 2013, healthcare providers at community health centers, private physician’s offices and local emergency departments began seeing previously healthy patients with complaints of abdominal pain throughout Napa County. 50
  • 51. Scenario (Continued) Within one day, 40 cases of bloody diarrhea had been reported by 10 healthcare providers at community health centers, private physician’s offices and local emergency departments in the county. Two days after the first reports of abdominal pain and bloody diarrhea, 4 patients (of which, 2 are pediatric) were admitted to the Intensive Care Unit with symptoms of decreased urine output, lethargy and persistent bloody diarrhea. These patients were diagnosed with hemolytic uremic syndrome. Cases presenting similar symptoms continue to be reported throughout the county. 51
  • 52. Scenario (Continued) Five days after the first reported case, 225 patients (approximately 10% with HUS) have been identified with similar presenting symptoms at local hospitals, community health centers and private physician practices. 52
  • 53. Scenario (Continued) Healthcare facility staff has requested guidance from the local Public Health Laboratory on appropriate protocols for specimen collection and laboratory techniques to confirm the diagnosis. Healthcare facilities are requesting guidance on necessary levels of isolation and personal protective equipment requirements for staff. 53
  • 54. Module 1: Public Health Surveillance and Epidemiological Investigation Key Issues:  Surveillance and epidemiological investigation coordinated with the healthcare partners  Implement control measures 54
  • 55. Questions for Discussion 1. When and how would your organization/agency be made aware of an increase in Shiga Toxin-producing E. coli isolates within your jurisdiction? a. Are there multiple modes of communication for this kind of information? 2. What would prompt an investigation, and who would undertake the investigation and analysis if an outbreak were to occur in your jurisdiction? 55
  • 56. Questions for Discussion 3. How does your organization/agency collaborate with the laboratories? a. How is testing prioritized? 4. How are control measures issued by Public Health, Environmental Health, healthcare facilities? a. How are the control measures implemented by each? 56
  • 58. Module 2: Emergency Public Information and Communications Key Issues:  Alerting and notification of personnel  Internal and external communications  Risk communication messaging 58
  • 59. Questions for Discussion 1. What mechanisms and/or technologies are in place to alert and notify your staff of activation of your facility’s emergency operations plan? a. How do you notify staff of activation? b. Who is responsible to do that? c. How often do you test this system? d. Has this system been used in a real event? e. Who else do you notify of activation? f. How does that occur? 59
  • 60. Questions for Discussion 2. How do you share information with Public Health? a. What information do you share? b. What information do you expect from Public Health? c. How do you communicate your facility status (and bed availability) to the local medical health system? d. How does this information get to the state? 60
  • 61. Questions for Discussion 3. What is your risk communication plan to notify staff, patients, clients and/or stakeholders of a foodborne illness outbreak? a. Who approves the information to be shared? b. What communication methods are used? c. How does your organization participate in a Joint Information System (JIS)? d. What would warrant opening a Joint Information Center (JIC)? e. How do you manage inquiries from the media, stakeholders, and the general public? 61
  • 62. Scenario (Continued) Ambulance companies are reporting an increase in call volume and extended delays in offloading patients at local emergency departments. Hospitals are experiencing continuing surge with increasing emergency department wait times. The initial epidemiologic investigation has not revealed a consistent pattern of age, race, occupation, geographic distribution or previous symptomatology among patients which might indicate a source of the offending agent. 62
  • 63. Module 3: Emergency Operations Center Management and Medical Surge Key Issues:  Response is coordinated through the use of Incident Command System principles and Command Centers/Emergency Operations Centers  Incident Action Plans are developed to guide and document the response and recovery phases  Activation of Surge Plans  Request and/or response to resource requests 63
  • 64. Questions for Discussion 1. How do you plan for an influx of patients including the access and functional needs population? a. What types of services can be altered, postponed or relocated to other sites? b. Have clinical providers been active in the decision making for alteration of services? 64
  • 65. Questions for Discussion 2. Which partner organizations can assist in providing services that you must alter or suspend due to a medical surge? a. Do you have Memoranda of Understanding signed with these partner organizations? 3. How do you request, respond to, distribute, track and/or return resources in accordance with the California Public Health and Medical Emergency Operations Manual? 65
  • 66. Resource Requesting Dr. Karen Smith Napa County Public Health Officer 66
  • 67.
  • 68. Medical & Public Health Resources • Personnel • Services • Supplies and Equipment • Transportation • Facilities 68
  • 69. Healthcare Facility Managers How to Obtain Resources: • Communication through accepted local protocols • Communicating resource arrangements minimized duplication of efforts 69
  • 70. HC Facility Resource Utilization • Determine if current resources will meet the anticipated needs • Prioritize/conserve what’s available • Contact suppliers/contractors • Implement existing agreements • Request help from the HHSA/DOC - MHOAC 70
  • 71.
  • 72. HHSA Department Operations Center (DOC) DOC Director PIO Health Officer Safety Officer Liaison Officer Operations Section Planning Section Logistics Section Finance Section Medical Branch Health Branch 72
  • 73. DOC Medical & Health Branch Operations Section Medical Branch Health Branch EMS/Transport Patient Tracking Communicable Disease Healthcare Facilities Coordination Laboratory Alternate Care Site Activate branches as needed Mass Prophylaxis 73
  • 74.
  • 75. CA Mutual Aid System • CA disaster & Civil Defense Master Mutual Aid Agreement (MAA) • Discipline-Specific Mutual Aid Agreements • Health Care Facilities Mutual Aid or Mutual Assistance Agreements 75
  • 76. CA Mutual Aid Regions 3 1 2 4 5 6 1 76
  • 77. Regional Disaster Medical & Health Coordinator/Specialist (RDMC/S) REOC Medical Health Branch RDMHC/S Program OA EOC Med. Health Branch MHOAC Program OA EOC Med. Health Branch MHOAC Program OA EOC Med. Health Branch MHOAC Program Affected Local Jurisdictions 77
  • 78.
  • 79. Who You Gonna Call? Public Health/ HHSA!!! Public Health/HHSA DOC is your gateway to CA’s mutual aid… 79
  • 82. Planning for the November Functional Exercise The scenario will be a medical surge due to foodborne illness. Customization of the exercise allows incorporating other objectives as needed. Examples include issues identified in past exercises, new training or equipment, or new policies and procedures. 82
  • 83. November Exercise Issues for Consideration Exercise Level of Play:  What level of exercise play do the organizations/agencies represented today anticipate for the November 21, 2013 exercise?  Examples include communications drill, functional and full scale exercises, level of play may include use of simulated patients, movement of patients to healthcare facilities, activation of the joint information center, provision of mutual aid, etc.  Will your organization/agency activate its Command Center/Emergency Operations Center? 83
  • 84. Role of State Agencies On November 21, 2013, the California Department of Public Health and the California Emergency Medical Services Authority will open the Medical and Health Coordination Center (Formerly the Joint Emergency Operations Center). The California Emergency Management Agency is anticipated to participate by opening the State Operations Center and the Regional Emergency Operations Centers to support local and regional exercise play. This will provide the opportunity for local participants to request additional resources, submit and receive situation status reports and respond to California Health Alert Network (or other notification systems) messages and receive further direction. 84
  • 86. Thank You For Your Participation Additional materials may be found on: California Statewide Medical and Health Training and Exercise Program website: 86

Editor's Notes

  1. 205 cases in 26 states.Cattle are considered the primary reservoir of E. coli O157, but fecal shedding by other domestic livestock and wildlife has been described.The outbreak was amplified because the contaminated spinach from one or a few farms was mixed with spinach from numerous other farms, then bagged by a few processors, marketed under several brands, and distributed nationally and internationally.
  2. Slide created by Rafael -
  3. Reference: http://emedicine.medscape.com/article/982025-treatment
  4. Reference: http://emedicine.medscape.com/article/982025-treatment
  5. CEIP is alerted when any foodborne outbreak is identified. They help to coordinate foodborne outbreak response in Bay Area counties (Alameda, Contra Costa, San Francisco) alongside CDPH
  6. The time from when a patient eats contaminated food to the when the public health lab completes confirmatory testing and fingerprintinghttp://www.cdc.gov/ecoli/reportingtimeline.htm A series of events occurs between the time a patient is infected and the time public health officials can determine that the patient is part of an outbreak. This means that there will be a delay between when a person gets sick and confirmation that he or she is part of an outbreak. Public health officials work hard to speed up the process as much as possible. The timeline is as follows:Incubation time: The time from eating the contaminated food to the beginning of symptoms. For E. coli O157, this is typically 3-4 days.Time to sample collection: The time from the first symptom until the person seeks medical care, when a diarrhea sample is collected for laboratory testing. This is typically 1-5 days.Time to diagnosis: The time from when a person gives a stool sample to when E. coli O157 is obtained from it in a laboratory. This may be 1-3 days from the time the sample is received in the laboratory. The diagnosis of E. coli infection may be reported to the local health department at this time.E. coli isolate shipping time: The time required to ship the E. coli O157 bacteria from the laboratory to the state public health authorities that will perform “DNA fingerprinting.” This may take 0-7 days depending on transportation arrangements within a state and the distance between the clinical laboratory and public health department.Time to serotyping and “DNA fingerprinting”: The time required for the state public health authorities to perform “DNA fingerprinting” on the E. coli O157 isolate and compare it with the pattern of the outbreak strain. Ideally, this can be accomplished in 1 day. However, many public health laboratories have limited staff and space, and experience multiple emergencies at the same time. Thus, the process may take 1-4 days.The time from the beginning of a person’s illness to the confirmation that he or she was part of an outbreak is typically about 2-3 weeks
  7. Further discussion: CMS waivers, L&amp;C waivers (Nursing staff ratios, Surge tents, etc.) CAL OSHA guidance, State Declarations and Gubernatorial Declarations