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Towards Development of a Low Cost and Portable ECG Monitoring System for
Rural/Remote Areas of Bangladesh
Article  in  International Journal of Image, Graphics and Signal Processing · May 2018
DOI: 10.5815/ijigsp.2018.05.03
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I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
Published Online May 2018 in MECS (http://www.mecs-press.org/)
DOI: 10.5815/ijigsp.2018.05.03
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
Towards Development of a Low Cost and
Portable ECG Monitoring System for
Rural/Remote Areas of Bangladesh
Sayed Tanvir Alam, Md. Moin Hossain, Md. Kafiul Islam
Dept. of Electrical and Electronic Engineering, Independent University, Bangladesh, Dhaka, Bangladesh
Email: sayedtanviralam@live.com, moint90@gmail.com, kafiul_islam@iub.edu.bd
Mohammad Dehan Rahman
Dept. of Electrical and Electronic Engineering, Islamic University of Technology, Dhaka, Bangladesh
Email: dehanrahman@gmail.com
Received: 08 January 2018; Accepted: 24 February 2018; Published: 08 May 2018
Abstract—An electrocardiogram (ECG) machine is a
device that checks the patient’s heart rhythm and
electrical activity. This is done by attaching sensors on
the skin of the patients. But the problem with these
machines is that these are expensive and not portable.
Thus it is difficult to use these machines in the rural or
remote areas of developing countries like Bangladesh
where the issue of portability and cost arises. In this paper,
the problem of cost and portability is addressed. We
propose a complete solution for a low-cost portable ECG
monitoring from recording to report generation for
patients including real-time ECG traces on screen with
storage options and calculation of all necessary
diagnostics parameters for helping the doctors to make a
decision. This type of ECG machines could be used in
hospitals, homes, villages or even in a disaster area. The
system designed in this paper includes a PC/Laptop, as
these devices are now widely available, at least available
at hospitals and healthcare centers, even in rural/remote
areas of Bangladesh. With this, a significant difference
can be made against heart diseases.
Index Terms—ECG, Portable, MATLAB, Arduino, Low
cost.
I. INTRODUCTION
One of the leading causes of human death is due to
cardiovascular diseases [2]. The first step to prevent such
diseases is to have an effective method of collecting,
monitoring and maintaining the health data of the patient.
Electrocardiography (ECG) or also known as EKG, most
commonly performed cardiology test, is the procedure of
recording the electrical activity of the heart over a period
of time using electrodes placed on the skin. These
electrodes sense the small electrical changes on the skin
that arise from the heart muscle's electrophysiological
pattern of depolarizing and repolarizing during each
heartbeat [10, 12, 15, 18]. For this purpose, a device
known as ECG machine is used to measure the electrical
activity the heart, transform it into an electrical signal and
display it on a monitor in real-time [13, 17]. Information
from the ECG machine can be used to give a diagnosis of
a wide range of heart conditions [20]. Commercially there
are different ECG monitoring systems and some of the
research works about monitoring systems are classified as:
i. Systems that record signals and perform analysis
offline.
ii. Systems that perform real-time monitoring.
iii. Systems that provide real-time signal classification.
When it comes to cardiovascular diagnosis, an ECG
machine is a must. But an ECG machine is very complex
to use and very expensive. Most of the ECG machines
used are not portable. However, in a developing country
such as Bangladesh, where two-thirds of the population
live in rural/remote areas, availability of a commercial
ECG machine becomes difficult due to cost and
portability. Advanced healthcare facilities have not yet
reached most of the rural areas of Bangladesh. An
advanced medical equipment, such as ECG monitoring
device, is not found in most these health care centers and
hospitals as traditional ECG monitoring devices are
highly expensive ranging from 50,000 BDT to 1,00,000
BDT. The health care centers and hospitals which have
an ECG monitoring device takes a high charge from the
patients for an ECG test which most of them cannot
afford. Thus, most of the people suffer from
underdiagnosis.
A number of research works had presented portable
and/or low-cost ECG monitoring system as found in the
literature [3-8]. However, none of them presented a
complete solution of ECG monitoring, i.e. from signal
recording to signal processing and analysis and finally to
generate a professional patient report that can be readily
used by the physicians. Few of them only concentrated on
efficient recording techniques while some others focused
on signal analysis/processing algorithms. The aim of this
Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 25
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
paper is not only to develop a low-cost ECG monitoring
machine that will be available and affordable but also
which can provide a complete solution of recording,
monitoring as well as report generation for the people
living in the rural/remote area so that they never suffer
from underdiagnosis of a heart problem.
II. METHODS
In this work, the experiment was performed on subjects
by connecting 3 disposable electrodes on their body. The
ECG signal of the heart was extracted using an electronic
circuit and viewed on a PC/Laptop in real time. The ECG
signal was also recorded for a minute and then was
digitally filtered using MATLAB. This was performed
for offline analysis of ECG signal and calculation of
detailed morphological values for vital diagnostic
parameters (so-called ECG characteristic points (PQRS)
such as heart-rate, HRV, pulse rate, etc.) leading to the
generation of a patient report. The heartbeat rate and the
RR interval of the subject are also calculated and shown
on an LCD in real time. This will eventually help the
doctors to diagnose any abnormal heart activity of the
patients. The overall process flow is depicted in fig. 1.
Fig.1. Overall process flow of the work.
III. ANALOG SYSTEM DESIGN
The design used in this paper consists of various parts.
All these parts are integrated together to make the device
and extract ECG signal from the patient. The ECG circuit
can be divided into the following parts:
• Electrodes.
• Dual DC voltage regulators.
• Instrumentation amplifier
• Active low –pass filter
• Clamper
Fig.2. Block diagram of the entire system.
The ECG circuit is then interfaced with a PC/Laptop
using an Arduino for real-time monitoring and offline
analysis that is performed using MATLAB. The Arduino
is also interfaced with an LCD to calculate and view
some basic morphological values in real time. The block
diagram below shows how all of these parts are integrated
together.
A. Electrodes
Electrodes are placed on the skin of the subject to
sense the electrical change. These electrodes can detect
the tiny electrical changes on the skin due depolarizing
and repolarizing of the heart muscles.
In this paper, three electrodes are used. Two electrodes
are connected to the chest and one is connected to the
right leg, which acts as the reference voltage for the other
two. Three electrodes are used to eliminate poor
connection noise.
Fig.3. Circular disposable electrodes and connectors used in this work.
B. Dual DC Voltage Regulator
The input voltage may not always be constant and may
fluctuate within a range. This fluctuation can damage the
circuit. Thus, a voltage regulator is implemented in the
design. The components used in this paper have an input
voltage range of 2.3V to 18V. If the input voltage rises
above 18V then the circuit will not work properly. For
this paper 7809 was used for positive 9 voltage and 7909
was used 9 negative voltage. Thus, for these ICs to work
an input of 12 volts or above is used. The schematic
diagram of the circuit and its hardware implementation is
shown below.
26 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
Fig.4. Schematic of dual DC voltage regulator.
C. Instrumentation Amplifier
An instrumentation amplifier [13, 16] is used in this
project to extract the ECG signal of the heart from a
subject by eliminating the noise. The instrumentation
amplifier used in this paper is AD620. The AD620 is a
low cost, high accuracy instrumentation amplifier that
requires only one external resistor to set gains of 1 to
10,000. For AD620, the gain of the amplifier can be
calculated using the following formula.
Av = 1 +
49.4 kΩ
RGain
(1)
The following diagram shows a schematic diagram of
this circuit.
Fig.5. Schematic of the circuit used to extract ECG signal of the heart.
The electrodes of circuit demonstrated above were
connected to a subject and the output was viewed on an
oscilloscope.
D. Low Pass Filter
In this paper, a low pass filter was used to eliminate
high frequency noise from the ECG signal [14]. A
second-order active low pass filter was used so that a
better frequency response can be obtained. The cutoff
frequency of a second order low pass filter can be
calculated using the formula provided below.
fc =
1
2π√R1R2C1C2
(2)
Fig.6. Output of AD620 observed on an oscilloscope.
The cutoff frequency used in this paper is 80Hz. The
cutoff frequency can be set lower but that attenuates some
of the high-frequency components of the actual ECG
signal and makes it hard for signal processing in the later
part of this paper. This does not affect the efficiency as
digital filtering is performed in the later part of this paper.
Fig.7. Schematic of active low pass filter.
The filter demonstrated above was fed with the signal
obtained using the instrumentation amplifier and the
output was viewed on an oscilloscope.
Fig.8. Filtered and unfiltered ECG signals viewed on the oscilloscope.
E. Clamper
The voltage of the signal generated by the circuit has a
positive and a negative cycle. However, Arduino, used in
later part of this paper, cannot process the negative
voltage and clips it to zero. To avoid this, a clamper
circuit is used to shift the whole signal above 0V by
adding a DC offset.
Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 27
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
Fig.9. Schematic diagram of clamper.
The clamper demonstrated above was fed with the
signal obtained from the filter and the output was viewed
on an oscilloscope.
F. Heartbeat Rate and RR Interval Measuring Circuit
The output obtained from the clamper is fed to an
Arduino to calculate heartbeat rate and its RR interval
and display the result on an LCD. The algorithm used to
obtain the measurements is discussed in the later part of
this paper.
Fig.10. ECG signal with and without DC offset to demonstrate the
function of Clamper circuit.
G. Schematic and Implementation of ECG circuit
All the circuits discussed above were integrated
together to work as a system. The schematic of the entire
system is provided in fig. 11. We have used Arduino
UNO for taking the analog frontend output and to make it
digital to feed into PC/laptop through the serial monitor.
Arduino UNO is also used to calculate the heart-rate (RR
interval) for showing on LCD which is interfaced with
Arduino.
Fig.11. Schematic diagram of the overall system.
IV. COMPUTER INTERFACING AND ALGORITHM
IMPLEMENTATION
This section discusses the interfacing between analog
frontend and computer/laptop and the algorithm
implementation on MATLAB platform for DSP part of
the system to find out the required diagnostic parameters
from recorded ECG signal.
A. Analog Circuit To PC/Laptop Interfacing Using
Arduino
The ECG circuit discussed above was interfaced with a
PC/Laptop using an Arduino. The signal obtained from
the ECG circuit was fed to an analog pin of the Arduino.
The Arduino was programmed to read the analog data,
perform analog to digital conversion and store the data is
a continuous loop. A sampling frequency of 785 Hz was
used to perform this process. The Arduino then was
connected to a PC/Laptop using a USB port. Once the
digital ECG signal is available on PC/Laptop, we can
perform digital signal processing using MATLAB to
remove noise/interference as well as to analyze ECG
signal characteristics for extracting diagnosis parameters
[9].
B. Real-Time Monitoring Using Serial Plotter
The Arduino IDE software was a built-in tool called
serial plotter. Real-time monitoring of ECG signal can be
easily performed using this tool. The data obtained by the
Arduino from the ECG circuit is sent to the serial plotter
by serial communication and the tool plots the data
accordingly. A baud rate of 115200 was used for the
serial communication channel.
C. Arduino to MATLAB Interface
28 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
The data from the Arduino is sent to MATLAB for
detailed signal processing. The data is sent using serial
communication at a baud rate of 115200. The algorithm
stores 6000 samples sent from the Arduino. The
algorithm reads a data per millisecond and therefore
stores the ECG signal of the subject for 1 minute. It then
plots the obtained data and displays the ECG signal. The
raw ECG signal recording of a subject for 1 minute is
provided below.
Fig.12. View of the overall hardware set-up with the subject for ECG
recording. ECG trace is observed on Serial Plotter of the laptop in real-
time.
Fig.13. Raw ECG recording shown on MATLAB
D. Power Line Interference and High-Frequency Noise
Removal
Power line interference coming from power supply
frequency of 50Hz and its harmonics are one of the
common noises that affect any biomedical recordings
[11]. To remove unwanted electrical interference, a
digital notch filter and a digital FIR low-pass filter were
designed in MATLAB and applied to the raw ECG signal
in this paper. To design the notch filter for power supply
noise removal an infinite impulse response (IIR) filter of
the cutoff frequency of 50 Hz and of order 2 was chosen.
Whereas to design the low pass filter for high-frequency
noise removal, a finite impulse response (FIR) filter of
cutoff frequency 80 Hz of order 256 was chosen. The
result obtained is provided below.
Fig.14. Effect of filtering on raw ECG signal: top to bottom represent
raw ECG, the output of 50-Hz notch filter and output of LPF
respectively.
Fig.15. Power spectral density estimate of ECG signal to demonstrate
the effect of notch filtering for removing power line interferences
E. QRS Complex Detection
If the QRS complexes of the ECG signal can be
detected, then ECG parameters can be measured in detail.
This complex procedure was accomplished by an open
source MATLAB algorithm called ‘cadio24’ of ‘redxlab’.
This open-source algorithm was developed by Kuldeep
Singh Rajput, Rohan Puri, Maulik Majmudar, M.D., Dr.
Ramesh Raskar along with their students Harsha Vardhan
Pokkalla, Aranya Goswami [1]. The flowchart in Fig. 16
shows how the algorithm works.
This algorithm was used to detect QRS complexes of
the ECG signal recorded from the subject using
MATLAB. The result obtained is provided in Fig. 17.
F. Measuring Morphologies Values
After QRS detection, the algorithm from ‘cardio24’
can measure 12 morphological values from the ECG
signal. The algorithm can be used measure the following
parameters:
i. Maximum heart rate
ii. Average heart rate
Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 29
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
iii. Minimum heart rate
iv. Total number of QRS complexes
v. Number of irregular beats
vi. Percentage of irregular beats
vii. Number of episodes with consecutive irregular
beats
viii. Average PR interval
ix. Average QRS Interval
x. Average QT Interval
xi. Number of P wave absences
xii. Number of episodes that has more than four
consecutive P wave absences
G. Automatic Report Generation
The morphological values calculated by the ‘cardio24’
algorithm was extracted, and a MATLAB algorithm was
written to dump the measurements made on a text file to
generate a report. The patient report automatically
generated from the ECG signal from the ECG circuit is
given below.
Fig.16. Flowchart of QRS detection algorithm adapted from [1].
Fig.17. QRS complex detection from ECG
H. Real Time Heartbeat Rate and RR Interval
Measurement
A circuit used in this paper to measure heartbeat rate
and RR interval in real time and to display it on an LCD
was discussed above. The algorithm will be discussed in
this section.
The point R of the ECG signal has the highest
amplitude and can easily be detected as a high pulse
when ECG signal is fed into a digital input port of an
Arduino. If this point is detected, it means that the heart
has made a beat. The following is the stepwise
explanation of the algorithm:
i. Reset Arduino timer.
ii. Start measuring time when the first high pulse is
detected.
iii. Stop measuring time after 10 high pulses are
detected.
iv. Convert the time measured from milliseconds to
seconds.
v. Divide the total time measured by 10. This gives
the average RR interval or basically the period of
the signal.
vi. Calculate the reciprocal of average RR interval.
This gives the number of beats in one second or
basically the frequency of the ECG signal.
vii. Multiple the value obtained from the previous step
by 60. The gives us the number of beats per
minute.
viii. Send the value to the LCD connected to the
Arduino.
ix. Repeat the steps again.
Fig.18. Snapshot of an automatically generated patient report based on
ECG parameters.
30 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
V. COST ANALYSIS AND DISCUSSION
We have attempted an approximated cost analysis for
the analog frontend hardware and it is obvious that it can
be made within 1,000 BDT (~11.50 USD), while the rest
of the part of the system including PC/laptop are already
available in the target healthcare facilities i.e. healthcare
centers or hospitals. This is quite remarkably cost-
effective in comparison with the commercial ECG
machines that cost in the range from 50, 000 BDT to
100,000 BDT (approx. 600 - 1,200 USD).
The finding provided in the table shows that the system
developed in this paper could efficiently extract the ECG
signal, display the trace on a Laptop and display some
basis morphological values on an LCD in real time. The
system can also be used for detailed offline analysis of
ECG signal. A wide range of morphological values can
be measured and can generate a report based on it. The
electronic components provide satisfactory output and a
pure ECG signal could be obtained after digital signal
processing. None of the component used in the system is
expensive and therefore, making the whole system of low
cost. The ECG circuit is connected to a laptop making the
whole system portable.
Table 1. Approximated cost of the components used in our proposed
system
Component
s Used
Quantit
y
Unit
Price
(USD)
Total
Cost
(USD)
Remarks
Arduino
UNO
01 7.00 7.00
ECG
Electrodes
03 0.10 0.30 Disposable / One
time use
AD620 01 2.15 2.15
LCD 01 7.20 7.20 Can be ignored
when interfaced
with PC/Laptop
LM741 01 0.15 0.15
Voltage
Regulator
7809/7909
02 0.15 0.30 Not required if
battery is used
9V Battery 02 035 0.70 In this work, the
circuit is tested with
lab power supply,
which can be
replaced with two
9V batteries
Others 1 set Lumps
um
1.00 Resistors,
Capacitors,
Connectors,
Jumpers, etc.
Total Cost of the System (without
LCD and Voltage Regulator)
$11.30
or
950
TK
<1000 Taka!!!
More realistic given
that a Laptop with
MATLAB installed
is available
Total Cost of the System (with
LCD but without Voltage
Regulator)
$18.50 Less realistic since
LCD is not required
when Laptop is
available
VI. CONCLUSION
After implementation of all the circuit components and
applying all the algorithms, it can be said that the system
developed is a robust system for ECG monitoring. The
system is portable, and the outputs obtained from each
part of the system are of satisfyingly high quality.
Therefore, the output of the system is reliable. The
system is cost-efficient, as only around 1500 BDT was
required to develop the system. The system can be used
for both real-time monitoring and detailed offline analysis.
The system only requires a Laptop as processing terminal
that is now even available in these rural or remote areas’
healthcare centers. Connecting the device to Laptop is
very easy. They can be connected just by using the USB
port of Laptop. The morphological values and the report
generated by the algorithm can help doctors make
diagnosis more easily.
VII. FUTURE WORK
The developed prototype system already serves its
purpose. However, there are a few numbers of advances
that can be made to make the system even better and
more user-friendly. Following are the future development
plan for this paper:
 Interfacing the circuit with a graphical LCD so that
a PC/Laptop and LCD is not required for online
monitoring.
 Develop an algorithm to automatically generate a
professional patient report.
 Inclusion of circuit isolation and right leg drive
circuit to the system to provide patient protection.
 Develop a smartphone application and interface
the circuit with it so that real-time analysis can be
performed using a smartphone.
 Covert the circuit into PCB. This will not only
make the hardware compact but also reduce the
noise affecting the ECG signal furthermore.
If the above-mentioned specifications can be included
in the system then the system will become more cost-
effective, efficient, wireless and multifunctional. The
system will solve the issues of ECG monitoring in the
rural/remote areas of Bangladesh fully.
ACKNOWLEDGMENT
The project is funded and technically supported by
Dept. of Electrical and Electronic Engineering (EEE),
Independent University, Bangladesh (IUB).
Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 31
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
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Authors’ Profiles
Sayed Tanvir Alam received the B.Sc.
degree in Electronic and
Telecommunication Engineering (ETE)
from Independent University,
Bangladesh (IUB) in 2017. At present he
is serving as a Network Support Engineer
at Systems Solutions & Development
Technologies (SSD-Tech) in Dhaka,
Bangladesh. His research interest
includes signal processing, computer networks and network
security and cryptography.
Md. Moin Hossain received B.Sc. degree
in Electronic and Telecommunication
Engineering (ETE) from Independent
University Bangladesh (IUB),in 2017.His
research interest includes ECG monitoring
in android apps and artificial neural
network.
32 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh
Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32
Mohammad Dehan Rahman will
receive his B.Sc. degree in Electrical and
Electronic Engineering (EEE) from
Islamic University of Technology (IUT),
Bangladesh in 2018. At present, he is a
fourth-year undergrad student at IUT. His
research interest includes signal
processing, power converters and
inverters.
Dr. Md. Kafiul Islam received his B.Sc.
in EEE from Islamic University of
Technology (IUT), Bangladesh in 2008
and Ph.D. degree in ECE from National
University of Singapore (NUS), Singapore
in 2015. He is currently serving as an
Assistant Professor at the dept. of EEE in
Independent University, Bangladesh (IUB)
since 2016. Dr. Islam is a member of IEEE
and IEEE EMBS society and serves as technical committee
member or reviewer for several international journals and
conferences. He has published/co-authored more than 10 peer-
reviewed journal articles and around 10 international conference
papers till now. His research expertise includes biomedical
instrumentation and signal processing, neural engineering,
brain-computer interfacing, etc.
How to cite this paper: Sayed Tanvir Alam, Md. Moin Hossain, Mohammad Dehan Rahman, Md. Kafiul Islam,"
Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh ",
International Journal of Image, Graphics and Signal Processing(IJIGSP), Vol.10, No.5, pp. 24-32, 2018.DOI:
10.5815/ijigsp.2018.05.03
View publication stats
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  • 1. See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/324823521 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh Article  in  International Journal of Image, Graphics and Signal Processing · May 2018 DOI: 10.5815/ijigsp.2018.05.03 CITATIONS 7 READS 4,853 4 authors, including: Some of the authors of this publication are also working on these related projects: Non-invasive/Minimally Invasive Blood Test for Newborn/Neonate Parameters View project Artifact Detection and Removal from Neural Signals View project Sayed Tanvir Alam Independent University, Bangladesh 1 PUBLICATION   7 CITATIONS    SEE PROFILE Mohammad Dehan Rahman Islamic University of Technology 7 PUBLICATIONS   9 CITATIONS    SEE PROFILE Md. Kafiul Islam Independent University, Bangladesh 88 PUBLICATIONS   660 CITATIONS    SEE PROFILE All content following this page was uploaded by Md. Kafiul Islam on 04 May 2018. The user has requested enhancement of the downloaded file.
  • 2. I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 Published Online May 2018 in MECS (http://www.mecs-press.org/) DOI: 10.5815/ijigsp.2018.05.03 Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh Sayed Tanvir Alam, Md. Moin Hossain, Md. Kafiul Islam Dept. of Electrical and Electronic Engineering, Independent University, Bangladesh, Dhaka, Bangladesh Email: sayedtanviralam@live.com, moint90@gmail.com, kafiul_islam@iub.edu.bd Mohammad Dehan Rahman Dept. of Electrical and Electronic Engineering, Islamic University of Technology, Dhaka, Bangladesh Email: dehanrahman@gmail.com Received: 08 January 2018; Accepted: 24 February 2018; Published: 08 May 2018 Abstract—An electrocardiogram (ECG) machine is a device that checks the patient’s heart rhythm and electrical activity. This is done by attaching sensors on the skin of the patients. But the problem with these machines is that these are expensive and not portable. Thus it is difficult to use these machines in the rural or remote areas of developing countries like Bangladesh where the issue of portability and cost arises. In this paper, the problem of cost and portability is addressed. We propose a complete solution for a low-cost portable ECG monitoring from recording to report generation for patients including real-time ECG traces on screen with storage options and calculation of all necessary diagnostics parameters for helping the doctors to make a decision. This type of ECG machines could be used in hospitals, homes, villages or even in a disaster area. The system designed in this paper includes a PC/Laptop, as these devices are now widely available, at least available at hospitals and healthcare centers, even in rural/remote areas of Bangladesh. With this, a significant difference can be made against heart diseases. Index Terms—ECG, Portable, MATLAB, Arduino, Low cost. I. INTRODUCTION One of the leading causes of human death is due to cardiovascular diseases [2]. The first step to prevent such diseases is to have an effective method of collecting, monitoring and maintaining the health data of the patient. Electrocardiography (ECG) or also known as EKG, most commonly performed cardiology test, is the procedure of recording the electrical activity of the heart over a period of time using electrodes placed on the skin. These electrodes sense the small electrical changes on the skin that arise from the heart muscle's electrophysiological pattern of depolarizing and repolarizing during each heartbeat [10, 12, 15, 18]. For this purpose, a device known as ECG machine is used to measure the electrical activity the heart, transform it into an electrical signal and display it on a monitor in real-time [13, 17]. Information from the ECG machine can be used to give a diagnosis of a wide range of heart conditions [20]. Commercially there are different ECG monitoring systems and some of the research works about monitoring systems are classified as: i. Systems that record signals and perform analysis offline. ii. Systems that perform real-time monitoring. iii. Systems that provide real-time signal classification. When it comes to cardiovascular diagnosis, an ECG machine is a must. But an ECG machine is very complex to use and very expensive. Most of the ECG machines used are not portable. However, in a developing country such as Bangladesh, where two-thirds of the population live in rural/remote areas, availability of a commercial ECG machine becomes difficult due to cost and portability. Advanced healthcare facilities have not yet reached most of the rural areas of Bangladesh. An advanced medical equipment, such as ECG monitoring device, is not found in most these health care centers and hospitals as traditional ECG monitoring devices are highly expensive ranging from 50,000 BDT to 1,00,000 BDT. The health care centers and hospitals which have an ECG monitoring device takes a high charge from the patients for an ECG test which most of them cannot afford. Thus, most of the people suffer from underdiagnosis. A number of research works had presented portable and/or low-cost ECG monitoring system as found in the literature [3-8]. However, none of them presented a complete solution of ECG monitoring, i.e. from signal recording to signal processing and analysis and finally to generate a professional patient report that can be readily used by the physicians. Few of them only concentrated on efficient recording techniques while some others focused on signal analysis/processing algorithms. The aim of this
  • 3. Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 25 Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 paper is not only to develop a low-cost ECG monitoring machine that will be available and affordable but also which can provide a complete solution of recording, monitoring as well as report generation for the people living in the rural/remote area so that they never suffer from underdiagnosis of a heart problem. II. METHODS In this work, the experiment was performed on subjects by connecting 3 disposable electrodes on their body. The ECG signal of the heart was extracted using an electronic circuit and viewed on a PC/Laptop in real time. The ECG signal was also recorded for a minute and then was digitally filtered using MATLAB. This was performed for offline analysis of ECG signal and calculation of detailed morphological values for vital diagnostic parameters (so-called ECG characteristic points (PQRS) such as heart-rate, HRV, pulse rate, etc.) leading to the generation of a patient report. The heartbeat rate and the RR interval of the subject are also calculated and shown on an LCD in real time. This will eventually help the doctors to diagnose any abnormal heart activity of the patients. The overall process flow is depicted in fig. 1. Fig.1. Overall process flow of the work. III. ANALOG SYSTEM DESIGN The design used in this paper consists of various parts. All these parts are integrated together to make the device and extract ECG signal from the patient. The ECG circuit can be divided into the following parts: • Electrodes. • Dual DC voltage regulators. • Instrumentation amplifier • Active low –pass filter • Clamper Fig.2. Block diagram of the entire system. The ECG circuit is then interfaced with a PC/Laptop using an Arduino for real-time monitoring and offline analysis that is performed using MATLAB. The Arduino is also interfaced with an LCD to calculate and view some basic morphological values in real time. The block diagram below shows how all of these parts are integrated together. A. Electrodes Electrodes are placed on the skin of the subject to sense the electrical change. These electrodes can detect the tiny electrical changes on the skin due depolarizing and repolarizing of the heart muscles. In this paper, three electrodes are used. Two electrodes are connected to the chest and one is connected to the right leg, which acts as the reference voltage for the other two. Three electrodes are used to eliminate poor connection noise. Fig.3. Circular disposable electrodes and connectors used in this work. B. Dual DC Voltage Regulator The input voltage may not always be constant and may fluctuate within a range. This fluctuation can damage the circuit. Thus, a voltage regulator is implemented in the design. The components used in this paper have an input voltage range of 2.3V to 18V. If the input voltage rises above 18V then the circuit will not work properly. For this paper 7809 was used for positive 9 voltage and 7909 was used 9 negative voltage. Thus, for these ICs to work an input of 12 volts or above is used. The schematic diagram of the circuit and its hardware implementation is shown below.
  • 4. 26 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 Fig.4. Schematic of dual DC voltage regulator. C. Instrumentation Amplifier An instrumentation amplifier [13, 16] is used in this project to extract the ECG signal of the heart from a subject by eliminating the noise. The instrumentation amplifier used in this paper is AD620. The AD620 is a low cost, high accuracy instrumentation amplifier that requires only one external resistor to set gains of 1 to 10,000. For AD620, the gain of the amplifier can be calculated using the following formula. Av = 1 + 49.4 kΩ RGain (1) The following diagram shows a schematic diagram of this circuit. Fig.5. Schematic of the circuit used to extract ECG signal of the heart. The electrodes of circuit demonstrated above were connected to a subject and the output was viewed on an oscilloscope. D. Low Pass Filter In this paper, a low pass filter was used to eliminate high frequency noise from the ECG signal [14]. A second-order active low pass filter was used so that a better frequency response can be obtained. The cutoff frequency of a second order low pass filter can be calculated using the formula provided below. fc = 1 2π√R1R2C1C2 (2) Fig.6. Output of AD620 observed on an oscilloscope. The cutoff frequency used in this paper is 80Hz. The cutoff frequency can be set lower but that attenuates some of the high-frequency components of the actual ECG signal and makes it hard for signal processing in the later part of this paper. This does not affect the efficiency as digital filtering is performed in the later part of this paper. Fig.7. Schematic of active low pass filter. The filter demonstrated above was fed with the signal obtained using the instrumentation amplifier and the output was viewed on an oscilloscope. Fig.8. Filtered and unfiltered ECG signals viewed on the oscilloscope. E. Clamper The voltage of the signal generated by the circuit has a positive and a negative cycle. However, Arduino, used in later part of this paper, cannot process the negative voltage and clips it to zero. To avoid this, a clamper circuit is used to shift the whole signal above 0V by adding a DC offset.
  • 5. Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 27 Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 Fig.9. Schematic diagram of clamper. The clamper demonstrated above was fed with the signal obtained from the filter and the output was viewed on an oscilloscope. F. Heartbeat Rate and RR Interval Measuring Circuit The output obtained from the clamper is fed to an Arduino to calculate heartbeat rate and its RR interval and display the result on an LCD. The algorithm used to obtain the measurements is discussed in the later part of this paper. Fig.10. ECG signal with and without DC offset to demonstrate the function of Clamper circuit. G. Schematic and Implementation of ECG circuit All the circuits discussed above were integrated together to work as a system. The schematic of the entire system is provided in fig. 11. We have used Arduino UNO for taking the analog frontend output and to make it digital to feed into PC/laptop through the serial monitor. Arduino UNO is also used to calculate the heart-rate (RR interval) for showing on LCD which is interfaced with Arduino. Fig.11. Schematic diagram of the overall system. IV. COMPUTER INTERFACING AND ALGORITHM IMPLEMENTATION This section discusses the interfacing between analog frontend and computer/laptop and the algorithm implementation on MATLAB platform for DSP part of the system to find out the required diagnostic parameters from recorded ECG signal. A. Analog Circuit To PC/Laptop Interfacing Using Arduino The ECG circuit discussed above was interfaced with a PC/Laptop using an Arduino. The signal obtained from the ECG circuit was fed to an analog pin of the Arduino. The Arduino was programmed to read the analog data, perform analog to digital conversion and store the data is a continuous loop. A sampling frequency of 785 Hz was used to perform this process. The Arduino then was connected to a PC/Laptop using a USB port. Once the digital ECG signal is available on PC/Laptop, we can perform digital signal processing using MATLAB to remove noise/interference as well as to analyze ECG signal characteristics for extracting diagnosis parameters [9]. B. Real-Time Monitoring Using Serial Plotter The Arduino IDE software was a built-in tool called serial plotter. Real-time monitoring of ECG signal can be easily performed using this tool. The data obtained by the Arduino from the ECG circuit is sent to the serial plotter by serial communication and the tool plots the data accordingly. A baud rate of 115200 was used for the serial communication channel. C. Arduino to MATLAB Interface
  • 6. 28 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 The data from the Arduino is sent to MATLAB for detailed signal processing. The data is sent using serial communication at a baud rate of 115200. The algorithm stores 6000 samples sent from the Arduino. The algorithm reads a data per millisecond and therefore stores the ECG signal of the subject for 1 minute. It then plots the obtained data and displays the ECG signal. The raw ECG signal recording of a subject for 1 minute is provided below. Fig.12. View of the overall hardware set-up with the subject for ECG recording. ECG trace is observed on Serial Plotter of the laptop in real- time. Fig.13. Raw ECG recording shown on MATLAB D. Power Line Interference and High-Frequency Noise Removal Power line interference coming from power supply frequency of 50Hz and its harmonics are one of the common noises that affect any biomedical recordings [11]. To remove unwanted electrical interference, a digital notch filter and a digital FIR low-pass filter were designed in MATLAB and applied to the raw ECG signal in this paper. To design the notch filter for power supply noise removal an infinite impulse response (IIR) filter of the cutoff frequency of 50 Hz and of order 2 was chosen. Whereas to design the low pass filter for high-frequency noise removal, a finite impulse response (FIR) filter of cutoff frequency 80 Hz of order 256 was chosen. The result obtained is provided below. Fig.14. Effect of filtering on raw ECG signal: top to bottom represent raw ECG, the output of 50-Hz notch filter and output of LPF respectively. Fig.15. Power spectral density estimate of ECG signal to demonstrate the effect of notch filtering for removing power line interferences E. QRS Complex Detection If the QRS complexes of the ECG signal can be detected, then ECG parameters can be measured in detail. This complex procedure was accomplished by an open source MATLAB algorithm called ‘cadio24’ of ‘redxlab’. This open-source algorithm was developed by Kuldeep Singh Rajput, Rohan Puri, Maulik Majmudar, M.D., Dr. Ramesh Raskar along with their students Harsha Vardhan Pokkalla, Aranya Goswami [1]. The flowchart in Fig. 16 shows how the algorithm works. This algorithm was used to detect QRS complexes of the ECG signal recorded from the subject using MATLAB. The result obtained is provided in Fig. 17. F. Measuring Morphologies Values After QRS detection, the algorithm from ‘cardio24’ can measure 12 morphological values from the ECG signal. The algorithm can be used measure the following parameters: i. Maximum heart rate ii. Average heart rate
  • 7. Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 29 Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 iii. Minimum heart rate iv. Total number of QRS complexes v. Number of irregular beats vi. Percentage of irregular beats vii. Number of episodes with consecutive irregular beats viii. Average PR interval ix. Average QRS Interval x. Average QT Interval xi. Number of P wave absences xii. Number of episodes that has more than four consecutive P wave absences G. Automatic Report Generation The morphological values calculated by the ‘cardio24’ algorithm was extracted, and a MATLAB algorithm was written to dump the measurements made on a text file to generate a report. The patient report automatically generated from the ECG signal from the ECG circuit is given below. Fig.16. Flowchart of QRS detection algorithm adapted from [1]. Fig.17. QRS complex detection from ECG H. Real Time Heartbeat Rate and RR Interval Measurement A circuit used in this paper to measure heartbeat rate and RR interval in real time and to display it on an LCD was discussed above. The algorithm will be discussed in this section. The point R of the ECG signal has the highest amplitude and can easily be detected as a high pulse when ECG signal is fed into a digital input port of an Arduino. If this point is detected, it means that the heart has made a beat. The following is the stepwise explanation of the algorithm: i. Reset Arduino timer. ii. Start measuring time when the first high pulse is detected. iii. Stop measuring time after 10 high pulses are detected. iv. Convert the time measured from milliseconds to seconds. v. Divide the total time measured by 10. This gives the average RR interval or basically the period of the signal. vi. Calculate the reciprocal of average RR interval. This gives the number of beats in one second or basically the frequency of the ECG signal. vii. Multiple the value obtained from the previous step by 60. The gives us the number of beats per minute. viii. Send the value to the LCD connected to the Arduino. ix. Repeat the steps again. Fig.18. Snapshot of an automatically generated patient report based on ECG parameters.
  • 8. 30 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 V. COST ANALYSIS AND DISCUSSION We have attempted an approximated cost analysis for the analog frontend hardware and it is obvious that it can be made within 1,000 BDT (~11.50 USD), while the rest of the part of the system including PC/laptop are already available in the target healthcare facilities i.e. healthcare centers or hospitals. This is quite remarkably cost- effective in comparison with the commercial ECG machines that cost in the range from 50, 000 BDT to 100,000 BDT (approx. 600 - 1,200 USD). The finding provided in the table shows that the system developed in this paper could efficiently extract the ECG signal, display the trace on a Laptop and display some basis morphological values on an LCD in real time. The system can also be used for detailed offline analysis of ECG signal. A wide range of morphological values can be measured and can generate a report based on it. The electronic components provide satisfactory output and a pure ECG signal could be obtained after digital signal processing. None of the component used in the system is expensive and therefore, making the whole system of low cost. The ECG circuit is connected to a laptop making the whole system portable. Table 1. Approximated cost of the components used in our proposed system Component s Used Quantit y Unit Price (USD) Total Cost (USD) Remarks Arduino UNO 01 7.00 7.00 ECG Electrodes 03 0.10 0.30 Disposable / One time use AD620 01 2.15 2.15 LCD 01 7.20 7.20 Can be ignored when interfaced with PC/Laptop LM741 01 0.15 0.15 Voltage Regulator 7809/7909 02 0.15 0.30 Not required if battery is used 9V Battery 02 035 0.70 In this work, the circuit is tested with lab power supply, which can be replaced with two 9V batteries Others 1 set Lumps um 1.00 Resistors, Capacitors, Connectors, Jumpers, etc. Total Cost of the System (without LCD and Voltage Regulator) $11.30 or 950 TK <1000 Taka!!! More realistic given that a Laptop with MATLAB installed is available Total Cost of the System (with LCD but without Voltage Regulator) $18.50 Less realistic since LCD is not required when Laptop is available VI. CONCLUSION After implementation of all the circuit components and applying all the algorithms, it can be said that the system developed is a robust system for ECG monitoring. The system is portable, and the outputs obtained from each part of the system are of satisfyingly high quality. Therefore, the output of the system is reliable. The system is cost-efficient, as only around 1500 BDT was required to develop the system. The system can be used for both real-time monitoring and detailed offline analysis. The system only requires a Laptop as processing terminal that is now even available in these rural or remote areas’ healthcare centers. Connecting the device to Laptop is very easy. They can be connected just by using the USB port of Laptop. The morphological values and the report generated by the algorithm can help doctors make diagnosis more easily. VII. FUTURE WORK The developed prototype system already serves its purpose. However, there are a few numbers of advances that can be made to make the system even better and more user-friendly. Following are the future development plan for this paper:  Interfacing the circuit with a graphical LCD so that a PC/Laptop and LCD is not required for online monitoring.  Develop an algorithm to automatically generate a professional patient report.  Inclusion of circuit isolation and right leg drive circuit to the system to provide patient protection.  Develop a smartphone application and interface the circuit with it so that real-time analysis can be performed using a smartphone.  Covert the circuit into PCB. This will not only make the hardware compact but also reduce the noise affecting the ECG signal furthermore. If the above-mentioned specifications can be included in the system then the system will become more cost- effective, efficient, wireless and multifunctional. The system will solve the issues of ECG monitoring in the rural/remote areas of Bangladesh fully. ACKNOWLEDGMENT The project is funded and technically supported by Dept. of Electrical and Electronic Engineering (EEE), Independent University, Bangladesh (IUB).
  • 9. Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh 31 Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 REFERENCES [1] QRS Detection Algorithm ‘cardio24’ by ‘redxlab’. Link: https://github.com/redxlab/cardio24/ [2] http://www.who.int/cardiovascular_diseases/en/ (accessed on 6th Jan, 2018). [3] Ertola, J. P., Silvia Figueira, Meghan Carlsen, Uma Palaniappan, and Kelsey Rondini. "Low-cost electrocardiogram device for preventive health care in rural populations of developing countries." In Global Humanitarian Technology Conference (GHTC), 2016, pp. 646-655. IEEE, 2016. [4] Christ, Gabriel, Shachi Kakkar, Michael McElroy, and Augustus Boling. "Low Cost SMS-Enabled EKG for Use in Developing Countries." (2017). [5] Deb, Sudip, Sheikh Md Rabiul Islam, Jannatul RobaiatMou, and Md Tariqul Islam. "Design and implementation of low cost ECG monitoring system for the patient using smart device." In Electrical, Computer and Communication Engineering (ECCE), International Conference on, pp. 774-778. IEEE, 2017. [6] Campillo, Daniel, Hector Torres, Rene Gonzá lez, Katia Valdé s, and Rolando Ló pez. "A portable device for a modular system of patient ECG monitoring." In Computing in Cardiology Conference (CinC), 2014, pp. 1077-1080. IEEE, 2014. [7] Ahamed, Md Asif, Md Kamrul Hasan, and Md Shahabul Alam. "Design and implementation of low cost ECG monitoring system for the patient using smartphone." In Electrical & Electronic Engineering (ICEEE), 2015 International Conference on, pp. 261-264. IEEE, 2015. [8] Murugappan, M., Reena Thirumani, Mohd Iqbal Omar, and Subbulakshmi Murugappan. "Development of cost effective ECG data acquisition system for clinical applications using LabVIEW." In Signal Processing & its Applications (CSPA), 2014 IEEE 10th International Colloquium on, pp. 100-105. IEEE, 2014. [9] Mitra, Sanjit Kumar, and Yonghong Kuo. Digital signal processing: a computer-based approach. Vol. 2. McGraw- Hill Higher Education, 2006. [10] Fye, W. Bruce. "A history of the origin, evolution, and impact of electrocardiography." The American journal of cardiology 73, no. 13 (1994): 937-949. [11] Wood, D. E., D. J. Ewins, and W. Balachandran. "Comparative analysis of power-line interference between two-or three-electrode biopotential amplifiers." Medical and Biological Engineering and Computing 33, no. 1 (1995): 63-68. [12] Snellen, Herman Adrianus. Willem Einthoven (1860– 1927) Father of electrocardiography: Life and work, ancestors and contemporaries. Springer Science & Business Media, 2012. [13] Khandpur, R. Biomedical instrumentation: Technology and applications. McGraw-Hill Prof Med/Tech, 2004. [14] Lacanette, Kerry. "A basic introduction to filters-active, passive, and switched-capacitor." 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Link: https://courses.lumenlearning.com/boundless- ap/chapter/the-heart/ (accessed on 6th Jan, 2018) [20] http://www.bem.fi/book/19/19.htm (accessed on 6th Jan, 2018) [21] Dey, Nilanjan, Sayantan Mukhopadhyay, Achintya Das, and Sheli Sinha Chaudhuri. "Analysis of P-QRS-T components modified by blind watermarking technique within the electrocardiogram signal for authentication in wireless telecardiology using DWT." International Journal of Image, Graphics and Signal Processing 4, no. 7 (2012): 33. [22] Ahmad, Ashraf Adamu, Aminu Inuwa Kuta, and Abdulmumini Zubairu Loko. "Analysis of Abdominal ECG Signal for Fetal Heart Rate Estimation Using Adaptive Filtering Technique." International Journal of Image, Graphics and Signal Processing 9, no. 2 (2017): 19. [23] Hartati, Sri, Retantyo Wardoyo, and Budi Yuli Setianto. "The Feature Extraction to Determine the Wave’s Peaks in the Electrocardiogram Graphic Image." International Journal of Image, Graphics and Signal Processing 9, no. 6 (2017): 1. Authors’ Profiles Sayed Tanvir Alam received the B.Sc. degree in Electronic and Telecommunication Engineering (ETE) from Independent University, Bangladesh (IUB) in 2017. At present he is serving as a Network Support Engineer at Systems Solutions & Development Technologies (SSD-Tech) in Dhaka, Bangladesh. His research interest includes signal processing, computer networks and network security and cryptography. Md. Moin Hossain received B.Sc. degree in Electronic and Telecommunication Engineering (ETE) from Independent University Bangladesh (IUB),in 2017.His research interest includes ECG monitoring in android apps and artificial neural network.
  • 10. 32 Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh Copyright © 2018 MECS I.J. Image, Graphics and Signal Processing, 2018, 5, 24-32 Mohammad Dehan Rahman will receive his B.Sc. degree in Electrical and Electronic Engineering (EEE) from Islamic University of Technology (IUT), Bangladesh in 2018. At present, he is a fourth-year undergrad student at IUT. His research interest includes signal processing, power converters and inverters. Dr. Md. Kafiul Islam received his B.Sc. in EEE from Islamic University of Technology (IUT), Bangladesh in 2008 and Ph.D. degree in ECE from National University of Singapore (NUS), Singapore in 2015. He is currently serving as an Assistant Professor at the dept. of EEE in Independent University, Bangladesh (IUB) since 2016. Dr. Islam is a member of IEEE and IEEE EMBS society and serves as technical committee member or reviewer for several international journals and conferences. He has published/co-authored more than 10 peer- reviewed journal articles and around 10 international conference papers till now. His research expertise includes biomedical instrumentation and signal processing, neural engineering, brain-computer interfacing, etc. How to cite this paper: Sayed Tanvir Alam, Md. Moin Hossain, Mohammad Dehan Rahman, Md. Kafiul Islam," Towards Development of a Low Cost and Portable ECG Monitoring System for Rural/Remote Areas of Bangladesh ", International Journal of Image, Graphics and Signal Processing(IJIGSP), Vol.10, No.5, pp. 24-32, 2018.DOI: 10.5815/ijigsp.2018.05.03 View publication stats View publication stats