Drug induced
(a)Oral mucosal pigmentation
Drug associated
*Antiplatelet agent:asprin, clopidrogel
*Anticoagulants:warfarin,bivalirudin
*NSAIDS:Ibuprofen, Piroxicam
*Antimalarial: Chloroquine Quinidine
*Antibiotics:Tetracycline,Minocycline
*oral contraceptives
(b) Lichenoid reaction
*ACE Inhibitors: Captopril, Ramipril
*NSAIDS:Indomethacin
*B-blockers: Propranolol,satalol
*Antiepileptics-carbamezepine
(c)Oral ulcers *NSAIDS:Piroxicam Naproxen
*Immunosuppresant: Tacrolimus, Sarolimus
*Anticancer agents:mTorr,MTKI’s
*Psychiatric agents:Antidepressants,
neuroleptics
(d)Oral bleeding
(e)Salivary glands
disturbances
*Anticholinergic drugs: Atropine, belladonna
*Diuretics:furosemide, Hydrochlorothiazide
*Antihypertensive:captopril
*Antihistamine: astemizole
(f)Taste disorder
*Calcium channel blockers: Nifidipine,Amilodipine
*Anti thyroid drugs: Carbamazole
*Antibiotics: metronidazole
(g)Oral Infection
*Gingival enlargement- phenytoin,sodium valproate
*Aphthous ulcer-NSAIDS, Captopril, Losartan
*Hairy tongue- Corticosteroids,Sulfonamides
INFLUENCEOFDRUGS INORALCAVITY