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© Cengage Learning 2015
8.3 What Is a Chromosome?
• DNA in a single human cell is about 2 meters (6.5 feet)
long
• How can that much DNA pack into a nucleus that is less
than 10 micrometers in diameter?
– Proteins associate with the DNA and help keep it organized
© Cengage Learning 2015
What Is a Chromosome? (cont’d.)
• Chromosome: structure that consists of DNA and
associated proteins
– Carries part or all of a cell’s genetic information
• Histone: type of protein that structurally organizes
eukaryotic chromosomes
• Nucleosome: a length of DNA wound twice around a
spool of histone proteins
© Cengage Learning 2015
What Is a Chromosome? (cont’d.)
• During most of a cell’s life, each chromosome consists of
one DNA molecule
• When the cell prepares to divide, it duplicates its
chromosomes by DNA replication
– After replication, each chromosome consists of two DNA
molecules (sister chromatids) that attach at a centromere
region
© Cengage Learning 2015
What Is a Chromosome? (cont’d.)
a chromosome
DNA replication
centromere
one chromatid
its sister chromatid
a chromosome
© Cengage Learning 2015
Chromosome Number and Type
• Each species has a characteristic chromosome number
(number of chromosomes in its cells)
– Examples:
• The chromosome number of oak trees is 12
• The chromosome number of humans is 46
© Cengage Learning 2015
Chromosome Number and Type (cont’d.)
• Human body cells have two sets of 23 chromosomes—
two of each type
– Having two sets of chromosomes means these cells are diploid
• Karyotype: an image of an individual’s diploid set of
chromosomes
© Cengage Learning 2015
Chromosome Number and Type (cont’d.)
• Autosome: a chromosome that is the same in males and
females
– Two autosomes of a pair have the same length, shape, and
centromere location
– They hold information about the same trait
© Cengage Learning 2015
Chromosome Number and Type (cont’d.)
• Members of a pair of sex chromosomes differ between
females and males
– The body cells of typical human females have two X
chromosomes (XX)
– The body cells of typical human males have one X and one Y
chromosome (XY)
• Environmental factors (not sex chromosomes) determine
sex in some invertebrates and reptiles
© Cengage Learning 2015
Chromosome Number and Type (cont’d.)

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8.3b

  • 1. © Cengage Learning 2015 8.3 What Is a Chromosome? • DNA in a single human cell is about 2 meters (6.5 feet) long • How can that much DNA pack into a nucleus that is less than 10 micrometers in diameter? – Proteins associate with the DNA and help keep it organized
  • 2. © Cengage Learning 2015 What Is a Chromosome? (cont’d.) • Chromosome: structure that consists of DNA and associated proteins – Carries part or all of a cell’s genetic information • Histone: type of protein that structurally organizes eukaryotic chromosomes • Nucleosome: a length of DNA wound twice around a spool of histone proteins
  • 3. © Cengage Learning 2015 What Is a Chromosome? (cont’d.) • During most of a cell’s life, each chromosome consists of one DNA molecule • When the cell prepares to divide, it duplicates its chromosomes by DNA replication – After replication, each chromosome consists of two DNA molecules (sister chromatids) that attach at a centromere region
  • 4. © Cengage Learning 2015 What Is a Chromosome? (cont’d.) a chromosome DNA replication centromere one chromatid its sister chromatid a chromosome
  • 5. © Cengage Learning 2015 Chromosome Number and Type • Each species has a characteristic chromosome number (number of chromosomes in its cells) – Examples: • The chromosome number of oak trees is 12 • The chromosome number of humans is 46
  • 6. © Cengage Learning 2015 Chromosome Number and Type (cont’d.) • Human body cells have two sets of 23 chromosomes— two of each type – Having two sets of chromosomes means these cells are diploid • Karyotype: an image of an individual’s diploid set of chromosomes
  • 7. © Cengage Learning 2015 Chromosome Number and Type (cont’d.) • Autosome: a chromosome that is the same in males and females – Two autosomes of a pair have the same length, shape, and centromere location – They hold information about the same trait
  • 8. © Cengage Learning 2015 Chromosome Number and Type (cont’d.) • Members of a pair of sex chromosomes differ between females and males – The body cells of typical human females have two X chromosomes (XX) – The body cells of typical human males have one X and one Y chromosome (XY) • Environmental factors (not sex chromosomes) determine sex in some invertebrates and reptiles
  • 9. © Cengage Learning 2015 Chromosome Number and Type (cont’d.)

Editor's Notes

  1. Figure 8.9 National Geographic Explorer Mariana Fuentes studies sea turtle populations. Climate change is an immediate, serious threat to these reptiles, in part because the temperature of the sand in which their eggs are buried—not sex chromosomes—determines the sex of the hatchlings. Fuentes predicts that rising global temperatures will soon skew the gender ratio of hatchlings toward all female, with disastrous results for sea turtle populations.