pharmacokinetics

2. quiz
1. Pharmacokinetic characteristics of propranolol include Vd = 300
L/70 kg, C1 = 700 mL/min, and oral bioavailability f = 0.25. What is
the dose needed to achieve a plasma level equivalent to a steadystate
level of 20 μg/L?
2.A 500-mg dose of a drug has therapeutic efficacy for 6 h. If the
halflife of the drug is 8 h, for how long would a 1-g dose be effective?