1. BREAST CANCER
PRESENTED BY:
MR. ABHAY RAJPOOT

2. INTRODUCTION
 Breast cancer is cancer that forms in the
cells of the breasts.
 After skin cancer, breast cancer is the
most common cancer diagnosed in
women in the United States. Breast
cancer can occur in both men and
women, but it's far more common in
women.

3. DEFINITION
 Brest cancer is that form of cancer that forms in the cells of the breast. It is
the most common cancer diagnosed in women

4. TYPES
 Angiosarcoma
 Ductal carcinoma in situ (DCIS)
 Inflammatory breast cancer
 Invasive lobular carcinoma
 Lobular carcinoma in situ (LCIS)
 Male breast cancer
 Paget's disease of the breast
 Recurrent breast cancer

5. Angiosarcoma of the skin
 Angiosarcoma is cancer that forms in the
lining of blood vessels and lymph vessels. It
often affects the skin and may appear as a
bruise-like lesion that grows over time.

6. Inflammatory breast cancer
 Inflammatory breast cancer often appears
as an enlarged breast with red, thickened
skin.

7. Invasive lobular carcinoma
 Invasive lobular carcinoma is a type of
breast cancer that begins in the milk-
producing glands (lobules) of the breast

8. Lobular carcinoma in situ
 Lobular carcinoma in situ (LCIS) develops
in a milk-producing gland (lobule) and
does not spread into nearby breast
tissue.

9. Male breast cancer
 Male breast cancer is a rare cancer that forms in the breast tissue of men.
Though breast cancer is most commonly thought of as a disease that
affects women, breast cancer does occur in men.
 Male breast cancer is most common in older men, though it can occur at
any age.

10. Paget's disease
Paget's disease of the breast occurs most often in
women older than age 50.
 Breast and nipple changes can be a sign of
breast cancer. Make an appointment with your
doctor if you notice anything unusual.

11. Recurrent breast
 Recurrent breast cancer is breast cancer that comes back after initial
treatment. Although the initial treatment is aimed at eliminating all cancer
cells, a few may have evaded treatment and survived.

12. RISK FACTORS
 Family history
 Age more than 45 years
 Late/early menopause
 Obesity
 Alcoholism
 Contraceptive pills
 Lack to breastfeeding to baby
 High fat diet
 Late marriage

13. CAUSES
 Heredity
 Chemical
 Obesity
 Hormonal
 Radiation

14. CLINICAL FEATURES
 A breast lump or thickening that feels different from the surrounding tissue
 Change in the size, shape or appearance of a breast
 Changes to the skin over the breast, such as dimpling
 A newly inverted nipple
 Peeling, scaling, crusting or flaking of the pigmented area of skin surrounding
the nipple (areola) or breast skin
 Redness or pitting of the skin over your breast, like the skin of an orange
 Mass – painless, 50% located in upper quadrant
 Nipple discharge (blood or serum)
 Breast asymmetry
 Nipple retraction
 Pain
 Ulceration
 Oedema

15. DIAGNOSTIC EVALUATION
 History
 Physical examination
 Mammography
 Biopsy / aspiration
 Chest X ray
 Breast self examination
 Axillary node sampling

16. SURGICAL MANAGEMENT
 Removing the breast cancer (lumpectomy). During a lumpectomy, which may be
referred to as breast-conserving surgery or wide local excision, the surgeon removes
the tumor and a small margin of surrounding healthy tissue.
 A lumpectomy may be recommended for removing smaller tumors. Some people with
larger tumors may undergo chemotherapy before surgery to shrink a tumor and make
it possible to remove completely with a lumpectomy procedure

18. MASTECTOMY
 Removing the entire breast (mastectomy). A mastectomy is an operation to
remove all of your breast tissue. Most mastectomy procedures remove all of
the breast tissue — the lobules, ducts, fatty tissue and some skin, including the
nipple and areola (total or simple mastectomy).

20.  Removing a limited number of lymph
nodes (sentinel node biopsy).

21. CHEMOTHERAPY
Chemotherapy is a widely used treatment for cancer. The term
chemotherapy refers to the drugs that prevent cancer cells from dividing
and growing. It does this by killing the dividing cells.
Ex.
-Vincristine
-Nethotrexate

23. Side effect
 Hair loss
 Nausea
 Vomiting
 Mouth sores
 Loss of appetite
 Tiredness, easy bruising or bleeding, and an increased chance of infection.

24. RADIATION THERAPY
Radiation therapy uses high energy radiation to target cancer cells.
Radiation therapy may be used in the treatment of leukemia that has
spread to the brain, or it may be used to target the spleen or other areas
where leukemia cells have accumulated.

25. HORMONAL THERAPY
 Hormone therapy can be used before or after surgery or other treatments
to decrease the chance of your cancer returning. If the cancer has already
spread, hormone therapy may shrink and control it
 Oestrogen and progesterone for breast cancer

26. IMMUNOTHERAPY
 Immunotherapy uses your immune system to fight cancer. The body's
disease-fighting immune system may not attack your cancer because the
cancer cells produce proteins that blind the immune system cells.
Immunotherapy works by interfering with that process.
 Eg- cytokines, interleukins

27. Thank You