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The Skeletal System
• Parts of the skeletal system       http://www.youtube.co
   • Bones (skeleton)                m/watch?v=8d-
   • Joints                          RBe8JBVs
   • Cartilages
   • Ligaments
• Two subdivisions of the skeleton
   • Axial skeleton
   • Appendicular skeleton




© 2012 Pearson Education, Inc.
Functions of Bones

       • Support the body
       • Protect soft organs
          • Skull and vertebrae for brain and spinal cord
          • Rib cage for thoracic cavity organs
       • Allow movement due to attached skeletal muscles
       • Store minerals and fats
          • Calcium and phosphorus
          • Fat in the internal marrow cavity
       • Blood cell formation (hematopoiesis)


© 2012 Pearson Education, Inc.
Bones of the Human Body
• The adult skeleton has 206 bones
• Two basic types of bone tissue
   1. Compact bone
     2. Spongy bone
        • Small needle-like pieces of
          bone
        • Many open spaces




© 2012 Pearson Education, Inc.
Classification of Bones on the Basis of Shape

• Bones are classified as:
   • Long
     • Short
     • Flat
     • Irregular




© 2012 Pearson Education, Inc.
Classification of Bones
• Long bones
   • Typically longer than they are wide
   • Shaft with heads situated at both ends
   • Contain mostly compact bone
   • All of the bones of the limbs
     (except wrist, ankle, and
     bones)
   • Example:
      • Femur
      • Humerus




© 2012 Pearson Education, Inc.
Classification of Bones
• Short bones
   • Generally cube-shaped
   • Contain mostly spongy bone
   • Includes bones of the wrist and ankle
   • Sesamoid bones are a type of short bone which form
     within tendons (patella)
   • Example:
       • Carpals
       • Tarsals




© 2012 Pearson Education, Inc.
Classification of Bones
• Flat bones
   • Thin, flattened, and usually curved
   • Two thin layers of compact bone
     surround a layer of spongy bone
   • Example:
      • Skull
           • Ribs
           • Sternum




© 2012 Pearson Education, Inc.
Classification of Bones
• Irregular bones
    • Irregular shape
    • Do not fit into other bone
      classification categories
    • Example:
        • Vertebrae
           • Hip bones




© 2012 Pearson Education, Inc.
Articular
                                             cartilage
       Anatomy of a Long Bone
• Diaphysis                      Proximal
   • Shaft                       epiphysis   Spongy bone
                                             Epiphyseal
   • Composed                                line
     of compact                              Periosteum
                                             Compact bone
     bone                                    Medullary
• Epiphysis                                  cavity (lined
                                             by endosteum)
                                 Diaphysis
   • Ends of the
     bone
   • Composed
     mostly of                                   http://www.youtube.
     spongy                                      com/watch?v=owlpf
     bone                                        6zHgyw
                                 Distal
                                 epiphysis
                                 (a)
                                                                Figure 5.3a
© 2012 Pearson Education, Inc.
Anatomy of a Long Bone

       • Periosteum
          • Outside covering of the diaphysis
          • Fibrous connective tissue membrane
       • Perforating (Sharpey’s) fibers
          • Secure periosteum to underlying bone
       • Arteries
          • Supply bone cells with nutrients


       • http://www.youtube.com/watch?v=8A0rRIpjutY&feature=r
         elmfu


© 2012 Pearson Education, Inc.
Endosteum




                    Yellow
                    bone marrow
                    Compact bone
                    Periosteum
                    Perforating
                    (Sharpey’s)
                    fibers
                    Nutrient
                    arteries
                             (c)
© 2012 Pearson Education, Inc.                 Figure 5.3c
Anatomy of a Long Bone
     Articular
     cartilage

                                          Compact bone
                                       • Articular cartilage
   Spongy bone                           • Covers the
                                           external
                                           surface of the
                                           epiphyses
                                         • Made of
                                           cartilage
                                 (b)     • Decreases
                                           friction at joint
                                           surfaces
© 2012 Pearson Education, Inc.                      Figure 5.3b
Anatomy of a                              Articular
                                             cartilage
   Long Bone
• Epiphyseal plate Proximal
                    epiphysis                Spongy bone
   • Flat plate of
                                             Epiphyseal
     hyaline                                 line
     cartilage seen                          Periosteum
     in young,                               Compact bone
     growing bone                            Medullary
                                             cavity (lined
• Epiphyseal line                            by endosteum)
                    Diaphysis
   • Remnant of
     the epiphyseal
     plate
   • Seen in adult
     bones


                                 Distal
                                 epiphysis
                                 (a)
© 2012 Pearson Education, Inc.                               Figure 5.3a
Anatomy of a Long Bone

       •Marrow (medullary) cavity
         •Cavity inside of the shaft
         •Contains yellow marrow (mostly fat) in
          adults
         •Contains red marrow for blood cell formation
          in infants
       •In adults, red marrow is situated in cavities of
        spongy bone and epiphyses of some long
        bones

© 2012 Pearson Education, Inc.
Microscopic Anatomy of Compact Bone

       •Osteon (Haversian system)
         •A unit of bone containing central canal and
          matrix rings
       •Central (Haversian) canal
         •Opening in the center of an osteon
         •Carries blood vessels and nerves
       •Perforating (Volkmann’s) canal
         •Canal perpendicular to the central canal
         •Carries blood vessels and nerves

© 2012 Pearson Education, Inc.
Osteon
                         (Haversian system)

                      Lamellae




                                                                     Blood vessel continues into
                                                                     medullary cavity containing marrow
                                                                     Spongy bone
   Perforating
   fibers
   Compact
   bone
   Periosteal
   blood vessel                               Central (Haversian) canal
   Periosteum
                                              Perforating
   (a)                                        (Volkmann’s) canal
                                              Blood vessel




© 2012 Pearson Education, Inc.                                                                Figure 5.4a
Microscopic Anatomy of Bone

       •Lacunae
         •Cavities containing bone cells (osteocytes)
         •Arranged in concentric rings called lamellae
       •Lamellae
         •Rings around the central canal
         •Sites of lacunae
       •http://www.youtube.com/watch?v=cNdwwVCpl
        d8&feature=relmfu


© 2012 Pearson Education, Inc.
Lamella
    Osteocyte




                                          Canaliculus
                                 (b)   Lacuna
                                       Central (Haversian) canal

© 2012 Pearson Education, Inc.                             Figure 5.4b
Osteon




               Lacuna


                                 (c) Central    Interstitial
© 2012 Pearson Education, Inc.
                                     canal      lamellae Figure 5.4c
Microscopic Anatomy of Bone

       •Canaliculi
         •Tiny canals
             •Radiate from the central canal to lacunae
             •Form a transport system connecting all bone
              cells to a nutrient supply
       •http://www.youtube.com/watch?v=CQhUINnT
        dZI&feature=relmfu



© 2012 Pearson Education, Inc.
Lamella
    Osteocyte                                      http://www.yo
                                                   utube.com/w
                                                   atch?v=ylma
                                                   nEGjRuY&fe
                                                   ature=relmfu




                                          Canaliculus
                                 (b)   Lacuna
                                       Central (Haversian) canal

© 2012 Pearson Education, Inc.                                Figure 5.4b
Formation of the Human Skeleton

       •In embryos, the skeleton is primarily hyaline
        cartilage
       •During development, much of this cartilage is
        replaced by bone – called ossification
       •Cartilage remains in isolated areas
             •Bridge of the nose
             •Parts of ribs
             •Joints


© 2012 Pearson Education, Inc.
Bone Growth (Ossification)

       •Epiphyseal plates allow for lengthwise growth
        of long bones during childhood
             •New cartilage is continuously formed
             •Older cartilage becomes ossified
               •Cartilage is broken down
                   •Enclosed cartilage is digested
                    away, opening up a medullary cavity
                   •Bone replaces cartilage through the action
                    of osteoblasts

© 2012 Pearson Education, Inc.
Bone Growth (Ossification)

       •Bones are remodeled and lengthened until
        growth stops
             •Bones are remodeled in response to two
              factors
               •Blood calcium levels
               •Pull of gravity and muscles on the
                skeleton
             •Bones grow in width (called appositional
              growth)

© 2012 Pearson Education, Inc.
http://www.youtube.c                                               Articular
  om/watch?v=t5_3sN                                                  cartilage

  LtfxQ                                        Hyaline
                                               cartilage
                                                                     Spongy
                                                                     bone
                         New center of
                         bone growth                                                                 New bone
                                                                     Epiphyseal                      forming
                                                                     plate
                                                                     cartilage                      Growth
                                 Medullary                                                          in bone
                                 cavity                                                             width
                       Bone starting                                 Invading
                       to replace                          Growth    blood
                       cartilage                           in bone   vessels
                                                           length
                                                                     New bone
                       Bone collar                                   forming
                       Hyaline                                       Epiphyseal
                       cartilage                                     plate cartilage
                       model
   In an embryo                              In a fetus                                In a child


© 2012 Pearson Education, Inc.                                                                          Figure 5.5
Types of Bone Cells

       •Osteocytes—mature bone cells
       •Osteoblasts—bone-forming cells
       •Osteoclasts—giant bone-destroying cells
         •Break down bone matrix for remodeling and
          release of calcium in response to
          parathyroid hormone
       •Bone remodeling is performed by both
        osteoblasts and osteoclasts


© 2012 Pearson Education, Inc.
Bone Fractures

       •Fracture—break in a bone
       •Types of bone fractures
         •Closed (simple) fracture—break that does
          not penetrate the skin
         •Compound fracture—broken bone
          penetrates through the skin
       •Bone fractures are treated by reduction and
        immobilization



© 2012 Pearson Education, Inc.
Common Types of Fractures
                                       http://www.youtube.com/w
                                       atch?v=c5Q5GPwAS4k
       •Comminuted—bone breaks into many
        fragments                    Setting a bone:
                                     http://www.youtube.com/watch?v=nQVih

       •Compression—bone is crushed
                                     uOUQkU&feature=related




       •Depressed—broken bone portion is pressed
        inward
       •Impacted—broken bone ends are forced into
        each other
       •Spiral—ragged break occurs when excessive
        twisting forces are applied to a bone
       •Greenstick—bone breaks incompletely
© 2012 Pearson Education, Inc.
Comminuted fracture




                                              Compression fracture




© 2012 Pearson Education, Inc.
Depressed fracture



                                        Impacted fracture




© 2012 Pearson Education, Inc.
Spiral fracture




                                      Greenstick fracture




© 2012 Pearson Education, Inc.
Logan’s leg –
    spiral,
    comminuted (he
    had fragments) &
    impacted




© 2012 Pearson Education, Inc.
Healing of bone fractures



                                 Hematoma
                                                                   External                    Bony
                                                                   callus                      callus of
                                                                                               spongy
                                                                                               bone
                                                                   New
                                 Internal                          blood
                                 callus                            vessels                     Healed
                                 (fibrous                                                      fracture
                                 tissue and                       Spongy
                                 cartilage)                       bone
                                                                  trabecula


         1 Hematoma                            2 Fibrocartilage                3 Bony callus          4 Bone remodeling
        forms.                                callus forms.                   forms.                 occurs.




© 2012 Pearson Education, Inc.                                                                                  Figure 5.7
Joints

       •Articulations of bones
       •Functions of joints
             •Hold bones together
             •Allow for mobility
       •Two ways joints are classified
         •Functionally
         •Structurally



© 2012 Pearson Education, Inc.
Features of Synovial Joints

       •Articular cartilage (hyaline cartilage) covers
        the ends of bones
       •Articular capsule encloses joint surfaces and
        lined with synovial membrane
       •Joint cavity is filled with synovial fluid
       •Reinforcing ligaments




© 2012 Pearson Education, Inc.
Acromion of
   scapula

   Ligament                                Joint cavity
                                           containing
   Bursa                                   synovial fluid
   Ligament
                                           Articular
                                           (hyaline)
   Tendon                                  cartilage
   sheath
                                           Synovial membrane

   Tendon of                               Fibrous layer of the
   biceps muscle                           articular capsule

                                 Humerus

© 2012 Pearson Education, Inc.                          Figure 5.31
Nonaxial
                                 Uniaxial
                                 Biaxial
                                 Multiaxial



                                              (a) Plane joint




                                     Flat articular surfaces, slipping
                                     or gliding movements,
                                     intercarpal joints of wrist is best
             (a)                     example




© 2012 Pearson Education, Inc.                                             Figure 5.32a
Nonaxial
                                 Uniaxial
                                 Biaxial
                                 Multiaxial
                                       One cylindrical surface & one
                                       trough-shaped surface, angular
                                       movement in one plane, elbow,
                       (b)             ankle, phalanges

                                                        Humerus
                                                        Ulna




                                      (b) Hinge joint



© 2012 Pearson Education, Inc.                                    Figure 5.32b
Nonaxial
                                 Uniaxial
                                 Biaxial
                                 Multiaxial
                                       Rounded end of one bone fits
                                       into a sleeve or ring of another,
                                       pivoting movement, proximal
                                       radioulnar joint

                                                           Ulna
                     (c)                                   Radius




                                      (c) Pivot joint



© 2012 Pearson Education, Inc.                                      Figure 5.32c
Nonaxial
                                 Uniaxial
                                 Biaxial
                                 Multiaxial

                                    Saddle like surfaces that fit
                                    together, side to side & back &
                                    forth movements,
                                    carpometacarpal joints of
                                    thumb (twiddle thumbs to see
                                    movements)
                                                            Carpal
                                                            Metacarpal #1


                      (e)


                                         (e) Saddle joint


© 2012 Pearson Education, Inc.                                              Figure 5.32e
Nonaxial
                                 Uniaxial
                                 Biaxial
                                 Multiaxial   One spherical head fits into
            (f)                               round socket of other, rotational
                                              movement (multiaxial),
                                              intercarpal joints of shoulder &
                                              hip


                                     Head of
                                     humerus




                                     Scapula
                                              (f) Ball-and-socket joint

© 2012 Pearson Education, Inc.                                             Figure 5.32f
Knee Replacement

   • Basic knee anatomy
   • http://www.youtube.com/watch?v=Xxyww3qAt0o
   •
   • Knee replacement surgery explained with diagram
   •
   • http://www.youtube.com/watch?v=wWQTm6qAPss
   •
   • Knee replacement surgery video - graphic but wonderfully
     explained & only 10 minutes. Let kids who don't want to see
     this go to either another room or to the lab area of the room.
   • http://www.youtube.com/watch?v=vJGJJOA1Me0

© 2012 Pearson Education, Inc.
Skeletal System Disorders & Diseases

       • Osteoarthritis – disease of the aged;
         degeneration of articular cartilage
       • Bursitis – inflammation of bursae
       • Rickets – disease of children in which bones fail
         to calcify; caused by vitamin D deficiency
         (needed to absorb Ca from intestines into blood)
       • Osteoporosis - the creation of new bone doesn't
         keep up with the removal of old bone. Most
         common in post menopausal white & Asian
         women.

© 2012 Pearson Education, Inc.
Osteoarthritis


© 2012 Pearson Education, Inc.
Bursitis




© 2012 Pearson Education, Inc.
Rickets



© 2012 Pearson Education, Inc.
Osteoporosis




© 2012 Pearson Education, Inc.
Importance of appropriate dietary Ca &
       strength of bones when young:

• Your bones are in a constant state of renewal — new
  bone is made and old bone is broken down.
• When you're young, your body makes new bone faster
  than it breaks down old bone and your bone mass
  increases.
• Most people reach their peak bone mass by their early
  20s. As people age, bone mass is lost faster than it's
  created.
• How likely you are to develop osteoporosis depends
  partly on how much bone mass you attained in your
  youth. The higher your peak bone mass, the more bone
  you have "in the bank" and the less likely you are to
  develop osteoporosis as you age.
© 2012 Pearson Education, Inc.
Developmental Aspects of the Skeletal
       System

       •At birth, the skull bones are incomplete
       •Bones are joined by fibrous membranes called
        fontanels
       •Fontanels are completely replaced with bone
        within two years after birth




© 2012 Pearson Education, Inc.
Parietal
                                              bone
                                 Frontal
                                 bone
                                 of skull
                                               Occipital
                                               bone

                                 Mandible
                                               Clavicle
                                               Scapula


                                 Radius
                                 Ulna
                                 Humerus

                                 Femur


                                 Tibia
                                                Ribs



                                            Vertebra
                                            Hip bone
© 2012 Pearson Education, Inc.                             Figure 5.34
© 2012 Pearson Education, Inc.   Figure 5.35a
© 2012 Pearson Education, Inc.   Figure 5.35b
The Axial Skeleton

       •Forms the longitudinal axis of the body
       •Divided into three parts
             •Skull
             •Vertebral column
             •Bony thorax




© 2012 Pearson Education, Inc.
Cranium
                                                Skull
                                                             Facial bones


                                                                       Clavicle
                                      Thoracic cage                    Scapula
                                      (ribs and
                                      sternum)                         Sternum
                                                                       Rib
                                                                       Humerus

                                                                       Vertebra
                                 Vertebral
                                 column                                Radius
                                                                       Ulna
                                   Sacrum
                                                                            Carpals




                                                                        Phalanges
                                                                        Metacarpals
                                                                        Femur
                                                                        Patella


                                                                        Tibia

                                                                        Fibula




                                                               Tarsals
                                                               Metatarsals
                                                               Phalanges
                                         (a) Anterior view
© 2012 Pearson Education, Inc.                                                        Figure 5.8a
The                                             Skull
                                                                      Cranium

                                                             Facial bones
Appendicular                                                           Clavicle

Skeleton                              Thoracic cage
                                      (ribs and
                                                                       Scapula

                                      sternum)                         Sternum
                                                                       Rib
                                                                       Humerus

                                                                       Vertebra
                                 Vertebral
                                 column                                Radius
                                                                       Ulna
                                   Sacrum
                                                                            Carpals




• Composed of 126                                                       Phalanges
  bones                                                                 Metacarpals
                                                                        Femur
   • Limbs                                                              Patella


     (appendages)                                                       Tibia


     • Pectoral girdle
                                                                        Fibula




     • Pelvic girdle                                           Tarsals
                                                               Metatarsals
                                                               Phalanges
                                         (a) Anterior view
© 2012 Pearson Education, Inc.                                                        Figure 5.8a
Cranium


                                                                          Bones of
                                 Clavicle                                 pectoral
                                                                          girdle
                                 Scapula
                                                                              Upper
                                                                              limb
                                 Rib
                                 Humerus

                                 Vertebra
                                 Radius                          Bones
                                 Ulna                            of
                                                                 pelvic
                                  Carpals                        girdle




                                 Phalanges
                                 Metacarpals
                                 Femur

                                                                           Lower
                                                                           limb
                                 Tibia

                                 Fibula




                                            (b) Posterior view
© 2012 Pearson Education, Inc.                                                        Figure 5.8b
Cranium
                                                Skull
                                                             Facial bones


                                                                       Clavicle
                                      Thoracic cage                    Scapula
                                      (ribs and
                                      sternum)                         Sternum
                                                                       Rib
                                                                       Humerus

                                                                       Vertebra
                                 Vertebral
                                 column                                Radius
                                                                       Ulna
                                   Sacrum
                                                                            Carpals




                                                                        Phalanges
                                                                        Metacarpals
                                                                        Femur
                                                                        Patella


                                                                        Tibia

                                                                        Fibula




                                                               Tarsals
                                                               Metatarsals
                                                               Phalanges
                                         (a) Anterior view
© 2012 Pearson Education, Inc.                                                        Figure 5.8a
The                                             Skull
                                                                      Cranium

                                                             Facial bones
Appendicular                                                           Clavicle

Skeleton                              Thoracic cage
                                      (ribs and
                                                                       Scapula

                                      sternum)                         Sternum
                                                                       Rib
                                                                       Humerus

                                                                       Vertebra
                                 Vertebral
                                 column                                Radius
                                                                       Ulna
                                   Sacrum
                                                                            Carpals




• Composed of 126                                                       Phalanges
  bones                                                                 Metacarpals
                                                                        Femur
   • Limbs                                                              Patella


     (appendages)                                                       Tibia


     • Pectoral girdle
                                                                        Fibula




     • Pelvic girdle                                           Tarsals
                                                               Metatarsals
                                                               Phalanges
                                         (a) Anterior view
© 2012 Pearson Education, Inc.                                                        Figure 5.8a
The Skull

       •Two sets of bones
         •Cranium
         •Facial bones
       •Bones are joined by sutures
       •Only the mandible is attached by a freely
        movable joint




© 2012 Pearson Education, Inc.
Coronal suture                                      Frontal bone

   Parietal bone
                                                       Sphenoid bone

   Temporal bone                                       Ethmoid bone

   Lambdoid                                            Lacrimal bone
   suture

   Squamous suture
                                                       Nasal bone
   Occipital bone

   Zygomatic process                                   Zygomatic bone
                                                       Maxilla
   External acoustic meatus
                 Mastoid process                       Alveolar
                                                       processes
                       Styloid process
                                                       Mandible (body)
                                                       Mental foramen
                                    Mandibular ramus




© 2012 Pearson Education, Inc.                                   Figure 5.9
Frontal bone

                                 Cribriform plate
                                                    Ethmoid
                                 Crista galli       bone
    Sphenoid
    bone                         Optic canal


                                 Sella turcica
                                 Foramen ovale

    Temporal bone

                                 Jugular foramen


    Internal
    acoustic meatus


    Parietal bone


    Occipital bone

             Foramen magnum


© 2012 Pearson Education, Inc.                      Figure 5.10
Maxilla
   Hard        (palatine process)
   palate
               Palatine bone
                                         Maxilla


   Zygomatic bone
                                         Sphenoid bone
   Temporal bone                         (greater wing)
   (zygomatic process)
                                         Foramen ovale
   Vomer

   Mandibular fossa
                                         Carotid canal
   Styloid process

   Mastoid process                       Jugular foramen


          Temporal bone              Occipital condyle


                    Parietal bone
                                    Foramen magnum
                 Occipital bone


© 2012 Pearson Education, Inc.                     Figure 5.11
Coronal suture
                                 Frontal bone
          Parietal bone




         Nasal bone
                                 Superior orbital fissure

         Sphenoid bone

                                 Optic canal
         Ethmoid bone
                                 Temporal bone
         Lacrimal bone
         Zygomatic bone
                                 Middle nasal concha
                                 of ethmoid bone
         Maxilla
                                 Inferior nasal concha

                                 Vomer
         Mandible

                                 Alveolar processes




© 2012 Pearson Education, Inc.                      Figure 5.12
Skull Links to videos & practice
• Calvaria bones explained
   • http://www.youtube.com/watch?v=9I0t9N-GIRM&feature=plcp
• Facial bones exlained
    • http://www.youtube.com/watch?v=0oEAyhcHqbE&feature=plc
      p
• Interactive Practice
    • http://msjensen.cehd.umn.edu/webanatomy/skeletons_skulls/s
      kull_lateral_7_m.html
• Interactive Practice: roll-over
    • http://www.gwc.maricopa.edu/class/bio201/skull/antskul.htm




© 2012 Pearson Education, Inc.
The Fetal Skull

       •The fetal skull is large compared to the infant’s
        total body length
         •Fetal skull is 1/4 body length compared to
          adult skull which is 1/8 body length
       •Fontanels—fibrous membranes connecting
        the cranial bones
         •Allow skull compression during birth
         •Allow the brain to grow during later
          pregnancy and infancy
         •Convert to bone within 24 months after birth

© 2012 Pearson Education, Inc.
Anterior
                                 fontanel
      Frontal bone




        Parietal
        bone


   Posterior fontanel
                                 Occipital
                                 bone
           (a)
© 2012 Pearson Education, Inc.      Figure 5.15a
Anterior fontanel
                                                      Sphenoidal
   Parietal bone                                      fontanel
                                                         Frontal
        Posterior                                        bone
        fontanel



   Occipital
   bone
   Mastoid
   fontanel
                                 Temporal bone
       (b)
© 2012 Pearson Education, Inc.                             Figure 5.15b
Craniosynostosis
           •Explanation video & Jack’s story

             http://www.youtube.com/watch?v=rfuT3d
             63-oo




                http://www.youtube.com/watch?v=
                ViAV9a9Ota8




© 2012 Pearson Education, Inc.
© 2012 Pearson Education, Inc.
© 2012 Pearson Education, Inc.

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The Skeletal System: Bones, Joints, and Functions

  • 1. The Skeletal System • Parts of the skeletal system http://www.youtube.co • Bones (skeleton) m/watch?v=8d- • Joints RBe8JBVs • Cartilages • Ligaments • Two subdivisions of the skeleton • Axial skeleton • Appendicular skeleton © 2012 Pearson Education, Inc.
  • 2. Functions of Bones • Support the body • Protect soft organs • Skull and vertebrae for brain and spinal cord • Rib cage for thoracic cavity organs • Allow movement due to attached skeletal muscles • Store minerals and fats • Calcium and phosphorus • Fat in the internal marrow cavity • Blood cell formation (hematopoiesis) © 2012 Pearson Education, Inc.
  • 3. Bones of the Human Body • The adult skeleton has 206 bones • Two basic types of bone tissue 1. Compact bone 2. Spongy bone • Small needle-like pieces of bone • Many open spaces © 2012 Pearson Education, Inc.
  • 4. Classification of Bones on the Basis of Shape • Bones are classified as: • Long • Short • Flat • Irregular © 2012 Pearson Education, Inc.
  • 5. Classification of Bones • Long bones • Typically longer than they are wide • Shaft with heads situated at both ends • Contain mostly compact bone • All of the bones of the limbs (except wrist, ankle, and bones) • Example: • Femur • Humerus © 2012 Pearson Education, Inc.
  • 6. Classification of Bones • Short bones • Generally cube-shaped • Contain mostly spongy bone • Includes bones of the wrist and ankle • Sesamoid bones are a type of short bone which form within tendons (patella) • Example: • Carpals • Tarsals © 2012 Pearson Education, Inc.
  • 7. Classification of Bones • Flat bones • Thin, flattened, and usually curved • Two thin layers of compact bone surround a layer of spongy bone • Example: • Skull • Ribs • Sternum © 2012 Pearson Education, Inc.
  • 8. Classification of Bones • Irregular bones • Irregular shape • Do not fit into other bone classification categories • Example: • Vertebrae • Hip bones © 2012 Pearson Education, Inc.
  • 9. Articular cartilage Anatomy of a Long Bone • Diaphysis Proximal • Shaft epiphysis Spongy bone Epiphyseal • Composed line of compact Periosteum Compact bone bone Medullary • Epiphysis cavity (lined by endosteum) Diaphysis • Ends of the bone • Composed mostly of http://www.youtube. spongy com/watch?v=owlpf bone 6zHgyw Distal epiphysis (a) Figure 5.3a © 2012 Pearson Education, Inc.
  • 10. Anatomy of a Long Bone • Periosteum • Outside covering of the diaphysis • Fibrous connective tissue membrane • Perforating (Sharpey’s) fibers • Secure periosteum to underlying bone • Arteries • Supply bone cells with nutrients • http://www.youtube.com/watch?v=8A0rRIpjutY&feature=r elmfu © 2012 Pearson Education, Inc.
  • 11. Endosteum Yellow bone marrow Compact bone Periosteum Perforating (Sharpey’s) fibers Nutrient arteries (c) © 2012 Pearson Education, Inc. Figure 5.3c
  • 12. Anatomy of a Long Bone Articular cartilage Compact bone • Articular cartilage Spongy bone • Covers the external surface of the epiphyses • Made of cartilage (b) • Decreases friction at joint surfaces © 2012 Pearson Education, Inc. Figure 5.3b
  • 13. Anatomy of a Articular cartilage Long Bone • Epiphyseal plate Proximal epiphysis Spongy bone • Flat plate of Epiphyseal hyaline line cartilage seen Periosteum in young, Compact bone growing bone Medullary cavity (lined • Epiphyseal line by endosteum) Diaphysis • Remnant of the epiphyseal plate • Seen in adult bones Distal epiphysis (a) © 2012 Pearson Education, Inc. Figure 5.3a
  • 14. Anatomy of a Long Bone •Marrow (medullary) cavity •Cavity inside of the shaft •Contains yellow marrow (mostly fat) in adults •Contains red marrow for blood cell formation in infants •In adults, red marrow is situated in cavities of spongy bone and epiphyses of some long bones © 2012 Pearson Education, Inc.
  • 15. Microscopic Anatomy of Compact Bone •Osteon (Haversian system) •A unit of bone containing central canal and matrix rings •Central (Haversian) canal •Opening in the center of an osteon •Carries blood vessels and nerves •Perforating (Volkmann’s) canal •Canal perpendicular to the central canal •Carries blood vessels and nerves © 2012 Pearson Education, Inc.
  • 16. Osteon (Haversian system) Lamellae Blood vessel continues into medullary cavity containing marrow Spongy bone Perforating fibers Compact bone Periosteal blood vessel Central (Haversian) canal Periosteum Perforating (a) (Volkmann’s) canal Blood vessel © 2012 Pearson Education, Inc. Figure 5.4a
  • 17. Microscopic Anatomy of Bone •Lacunae •Cavities containing bone cells (osteocytes) •Arranged in concentric rings called lamellae •Lamellae •Rings around the central canal •Sites of lacunae •http://www.youtube.com/watch?v=cNdwwVCpl d8&feature=relmfu © 2012 Pearson Education, Inc.
  • 18. Lamella Osteocyte Canaliculus (b) Lacuna Central (Haversian) canal © 2012 Pearson Education, Inc. Figure 5.4b
  • 19. Osteon Lacuna (c) Central Interstitial © 2012 Pearson Education, Inc. canal lamellae Figure 5.4c
  • 20. Microscopic Anatomy of Bone •Canaliculi •Tiny canals •Radiate from the central canal to lacunae •Form a transport system connecting all bone cells to a nutrient supply •http://www.youtube.com/watch?v=CQhUINnT dZI&feature=relmfu © 2012 Pearson Education, Inc.
  • 21. Lamella Osteocyte http://www.yo utube.com/w atch?v=ylma nEGjRuY&fe ature=relmfu Canaliculus (b) Lacuna Central (Haversian) canal © 2012 Pearson Education, Inc. Figure 5.4b
  • 22. Formation of the Human Skeleton •In embryos, the skeleton is primarily hyaline cartilage •During development, much of this cartilage is replaced by bone – called ossification •Cartilage remains in isolated areas •Bridge of the nose •Parts of ribs •Joints © 2012 Pearson Education, Inc.
  • 23. Bone Growth (Ossification) •Epiphyseal plates allow for lengthwise growth of long bones during childhood •New cartilage is continuously formed •Older cartilage becomes ossified •Cartilage is broken down •Enclosed cartilage is digested away, opening up a medullary cavity •Bone replaces cartilage through the action of osteoblasts © 2012 Pearson Education, Inc.
  • 24. Bone Growth (Ossification) •Bones are remodeled and lengthened until growth stops •Bones are remodeled in response to two factors •Blood calcium levels •Pull of gravity and muscles on the skeleton •Bones grow in width (called appositional growth) © 2012 Pearson Education, Inc.
  • 25. http://www.youtube.c Articular om/watch?v=t5_3sN cartilage LtfxQ Hyaline cartilage Spongy bone New center of bone growth New bone Epiphyseal forming plate cartilage Growth Medullary in bone cavity width Bone starting Invading to replace Growth blood cartilage in bone vessels length New bone Bone collar forming Hyaline Epiphyseal cartilage plate cartilage model In an embryo In a fetus In a child © 2012 Pearson Education, Inc. Figure 5.5
  • 26. Types of Bone Cells •Osteocytes—mature bone cells •Osteoblasts—bone-forming cells •Osteoclasts—giant bone-destroying cells •Break down bone matrix for remodeling and release of calcium in response to parathyroid hormone •Bone remodeling is performed by both osteoblasts and osteoclasts © 2012 Pearson Education, Inc.
  • 27. Bone Fractures •Fracture—break in a bone •Types of bone fractures •Closed (simple) fracture—break that does not penetrate the skin •Compound fracture—broken bone penetrates through the skin •Bone fractures are treated by reduction and immobilization © 2012 Pearson Education, Inc.
  • 28. Common Types of Fractures http://www.youtube.com/w atch?v=c5Q5GPwAS4k •Comminuted—bone breaks into many fragments Setting a bone: http://www.youtube.com/watch?v=nQVih •Compression—bone is crushed uOUQkU&feature=related •Depressed—broken bone portion is pressed inward •Impacted—broken bone ends are forced into each other •Spiral—ragged break occurs when excessive twisting forces are applied to a bone •Greenstick—bone breaks incompletely © 2012 Pearson Education, Inc.
  • 29. Comminuted fracture Compression fracture © 2012 Pearson Education, Inc.
  • 30. Depressed fracture Impacted fracture © 2012 Pearson Education, Inc.
  • 31. Spiral fracture Greenstick fracture © 2012 Pearson Education, Inc.
  • 32. Logan’s leg – spiral, comminuted (he had fragments) & impacted © 2012 Pearson Education, Inc.
  • 33. Healing of bone fractures Hematoma External Bony callus callus of spongy bone New Internal blood callus vessels Healed (fibrous fracture tissue and Spongy cartilage) bone trabecula 1 Hematoma 2 Fibrocartilage 3 Bony callus 4 Bone remodeling forms. callus forms. forms. occurs. © 2012 Pearson Education, Inc. Figure 5.7
  • 34. Joints •Articulations of bones •Functions of joints •Hold bones together •Allow for mobility •Two ways joints are classified •Functionally •Structurally © 2012 Pearson Education, Inc.
  • 35. Features of Synovial Joints •Articular cartilage (hyaline cartilage) covers the ends of bones •Articular capsule encloses joint surfaces and lined with synovial membrane •Joint cavity is filled with synovial fluid •Reinforcing ligaments © 2012 Pearson Education, Inc.
  • 36. Acromion of scapula Ligament Joint cavity containing Bursa synovial fluid Ligament Articular (hyaline) Tendon cartilage sheath Synovial membrane Tendon of Fibrous layer of the biceps muscle articular capsule Humerus © 2012 Pearson Education, Inc. Figure 5.31
  • 37. Nonaxial Uniaxial Biaxial Multiaxial (a) Plane joint Flat articular surfaces, slipping or gliding movements, intercarpal joints of wrist is best (a) example © 2012 Pearson Education, Inc. Figure 5.32a
  • 38. Nonaxial Uniaxial Biaxial Multiaxial One cylindrical surface & one trough-shaped surface, angular movement in one plane, elbow, (b) ankle, phalanges Humerus Ulna (b) Hinge joint © 2012 Pearson Education, Inc. Figure 5.32b
  • 39. Nonaxial Uniaxial Biaxial Multiaxial Rounded end of one bone fits into a sleeve or ring of another, pivoting movement, proximal radioulnar joint Ulna (c) Radius (c) Pivot joint © 2012 Pearson Education, Inc. Figure 5.32c
  • 40. Nonaxial Uniaxial Biaxial Multiaxial Saddle like surfaces that fit together, side to side & back & forth movements, carpometacarpal joints of thumb (twiddle thumbs to see movements) Carpal Metacarpal #1 (e) (e) Saddle joint © 2012 Pearson Education, Inc. Figure 5.32e
  • 41. Nonaxial Uniaxial Biaxial Multiaxial One spherical head fits into (f) round socket of other, rotational movement (multiaxial), intercarpal joints of shoulder & hip Head of humerus Scapula (f) Ball-and-socket joint © 2012 Pearson Education, Inc. Figure 5.32f
  • 42. Knee Replacement • Basic knee anatomy • http://www.youtube.com/watch?v=Xxyww3qAt0o • • Knee replacement surgery explained with diagram • • http://www.youtube.com/watch?v=wWQTm6qAPss • • Knee replacement surgery video - graphic but wonderfully explained & only 10 minutes. Let kids who don't want to see this go to either another room or to the lab area of the room. • http://www.youtube.com/watch?v=vJGJJOA1Me0 © 2012 Pearson Education, Inc.
  • 43. Skeletal System Disorders & Diseases • Osteoarthritis – disease of the aged; degeneration of articular cartilage • Bursitis – inflammation of bursae • Rickets – disease of children in which bones fail to calcify; caused by vitamin D deficiency (needed to absorb Ca from intestines into blood) • Osteoporosis - the creation of new bone doesn't keep up with the removal of old bone. Most common in post menopausal white & Asian women. © 2012 Pearson Education, Inc.
  • 45. Bursitis © 2012 Pearson Education, Inc.
  • 46. Rickets © 2012 Pearson Education, Inc.
  • 47. Osteoporosis © 2012 Pearson Education, Inc.
  • 48. Importance of appropriate dietary Ca & strength of bones when young: • Your bones are in a constant state of renewal — new bone is made and old bone is broken down. • When you're young, your body makes new bone faster than it breaks down old bone and your bone mass increases. • Most people reach their peak bone mass by their early 20s. As people age, bone mass is lost faster than it's created. • How likely you are to develop osteoporosis depends partly on how much bone mass you attained in your youth. The higher your peak bone mass, the more bone you have "in the bank" and the less likely you are to develop osteoporosis as you age. © 2012 Pearson Education, Inc.
  • 49. Developmental Aspects of the Skeletal System •At birth, the skull bones are incomplete •Bones are joined by fibrous membranes called fontanels •Fontanels are completely replaced with bone within two years after birth © 2012 Pearson Education, Inc.
  • 50. Parietal bone Frontal bone of skull Occipital bone Mandible Clavicle Scapula Radius Ulna Humerus Femur Tibia Ribs Vertebra Hip bone © 2012 Pearson Education, Inc. Figure 5.34
  • 51. © 2012 Pearson Education, Inc. Figure 5.35a
  • 52. © 2012 Pearson Education, Inc. Figure 5.35b
  • 53. The Axial Skeleton •Forms the longitudinal axis of the body •Divided into three parts •Skull •Vertebral column •Bony thorax © 2012 Pearson Education, Inc.
  • 54. Cranium Skull Facial bones Clavicle Thoracic cage Scapula (ribs and sternum) Sternum Rib Humerus Vertebra Vertebral column Radius Ulna Sacrum Carpals Phalanges Metacarpals Femur Patella Tibia Fibula Tarsals Metatarsals Phalanges (a) Anterior view © 2012 Pearson Education, Inc. Figure 5.8a
  • 55. The Skull Cranium Facial bones Appendicular Clavicle Skeleton Thoracic cage (ribs and Scapula sternum) Sternum Rib Humerus Vertebra Vertebral column Radius Ulna Sacrum Carpals • Composed of 126 Phalanges bones Metacarpals Femur • Limbs Patella (appendages) Tibia • Pectoral girdle Fibula • Pelvic girdle Tarsals Metatarsals Phalanges (a) Anterior view © 2012 Pearson Education, Inc. Figure 5.8a
  • 56. Cranium Bones of Clavicle pectoral girdle Scapula Upper limb Rib Humerus Vertebra Radius Bones Ulna of pelvic Carpals girdle Phalanges Metacarpals Femur Lower limb Tibia Fibula (b) Posterior view © 2012 Pearson Education, Inc. Figure 5.8b
  • 57. Cranium Skull Facial bones Clavicle Thoracic cage Scapula (ribs and sternum) Sternum Rib Humerus Vertebra Vertebral column Radius Ulna Sacrum Carpals Phalanges Metacarpals Femur Patella Tibia Fibula Tarsals Metatarsals Phalanges (a) Anterior view © 2012 Pearson Education, Inc. Figure 5.8a
  • 58. The Skull Cranium Facial bones Appendicular Clavicle Skeleton Thoracic cage (ribs and Scapula sternum) Sternum Rib Humerus Vertebra Vertebral column Radius Ulna Sacrum Carpals • Composed of 126 Phalanges bones Metacarpals Femur • Limbs Patella (appendages) Tibia • Pectoral girdle Fibula • Pelvic girdle Tarsals Metatarsals Phalanges (a) Anterior view © 2012 Pearson Education, Inc. Figure 5.8a
  • 59. The Skull •Two sets of bones •Cranium •Facial bones •Bones are joined by sutures •Only the mandible is attached by a freely movable joint © 2012 Pearson Education, Inc.
  • 60. Coronal suture Frontal bone Parietal bone Sphenoid bone Temporal bone Ethmoid bone Lambdoid Lacrimal bone suture Squamous suture Nasal bone Occipital bone Zygomatic process Zygomatic bone Maxilla External acoustic meatus Mastoid process Alveolar processes Styloid process Mandible (body) Mental foramen Mandibular ramus © 2012 Pearson Education, Inc. Figure 5.9
  • 61. Frontal bone Cribriform plate Ethmoid Crista galli bone Sphenoid bone Optic canal Sella turcica Foramen ovale Temporal bone Jugular foramen Internal acoustic meatus Parietal bone Occipital bone Foramen magnum © 2012 Pearson Education, Inc. Figure 5.10
  • 62. Maxilla Hard (palatine process) palate Palatine bone Maxilla Zygomatic bone Sphenoid bone Temporal bone (greater wing) (zygomatic process) Foramen ovale Vomer Mandibular fossa Carotid canal Styloid process Mastoid process Jugular foramen Temporal bone Occipital condyle Parietal bone Foramen magnum Occipital bone © 2012 Pearson Education, Inc. Figure 5.11
  • 63. Coronal suture Frontal bone Parietal bone Nasal bone Superior orbital fissure Sphenoid bone Optic canal Ethmoid bone Temporal bone Lacrimal bone Zygomatic bone Middle nasal concha of ethmoid bone Maxilla Inferior nasal concha Vomer Mandible Alveolar processes © 2012 Pearson Education, Inc. Figure 5.12
  • 64. Skull Links to videos & practice • Calvaria bones explained • http://www.youtube.com/watch?v=9I0t9N-GIRM&feature=plcp • Facial bones exlained • http://www.youtube.com/watch?v=0oEAyhcHqbE&feature=plc p • Interactive Practice • http://msjensen.cehd.umn.edu/webanatomy/skeletons_skulls/s kull_lateral_7_m.html • Interactive Practice: roll-over • http://www.gwc.maricopa.edu/class/bio201/skull/antskul.htm © 2012 Pearson Education, Inc.
  • 65. The Fetal Skull •The fetal skull is large compared to the infant’s total body length •Fetal skull is 1/4 body length compared to adult skull which is 1/8 body length •Fontanels—fibrous membranes connecting the cranial bones •Allow skull compression during birth •Allow the brain to grow during later pregnancy and infancy •Convert to bone within 24 months after birth © 2012 Pearson Education, Inc.
  • 66. Anterior fontanel Frontal bone Parietal bone Posterior fontanel Occipital bone (a) © 2012 Pearson Education, Inc. Figure 5.15a
  • 67. Anterior fontanel Sphenoidal Parietal bone fontanel Frontal Posterior bone fontanel Occipital bone Mastoid fontanel Temporal bone (b) © 2012 Pearson Education, Inc. Figure 5.15b
  • 68. Craniosynostosis •Explanation video & Jack’s story http://www.youtube.com/watch?v=rfuT3d 63-oo http://www.youtube.com/watch?v= ViAV9a9Ota8 © 2012 Pearson Education, Inc.
  • 69. © 2012 Pearson Education, Inc.
  • 70. © 2012 Pearson Education, Inc.