Combating user fatigue in iGA: partial ordering, support vector machines, and synthetic fitness

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Xavier Llorà

Technologie Gesundheit & Medizin

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One hundred and fifty years have passed since the publication of Darwin's world-changing manuscript "The Origins of Species by Means of Natural Selection". Darwin's ideas have proven their power to reach beyond the biology realm, and their ability to define a conceptual framework which allows us to model and understand complex systems. In the mid 1950s and 60s the efforts of a scattered group of engineers proved the benefits of adopting an evolutionary paradigm to solve complex real-world problems. In the 70s, the emerging presence of computers brought us a new collection of artificial evolution paradigms, among which genetic algorithms rapidly gained widespread adoption. Currently, the Internet has propitiated an exponential growth of information and computational resources that are clearly disrupting our perception and forcing us to reevaluate the boundaries between technology and social interaction. Darwin's ideas can, once again, help us understand such disruptive change. In this talk, I will review the origin of artificial evolution ideas and techniques. I will also show how these techniques are, nowadays, helping to solve a wide range of applications, from life science problems to twitter puzzles, and how high performance computing can make Darwin ideas a routinary tool to help us model and understand complex systems.

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We are living in the peta-byte era.We have larger and larger data to analyze, process and transform into useful answers for the domain experts. Robust data mining tools, able to cope with petascale volumes and/or high dimensionality producing human-understandable solutions are key on several domain areas. Genetics-based machine learning (GBML) techniques are perfect candidates for this task, among others, due to the recent advances in representations, learning paradigms, and theoretical modeling. If evolutionary learning techniques aspire to be a relevant player in this context, they need to have the capacity of processing these vast amounts of data and they need to process this data within reasonable time. Moreover, massive computation cycles are getting cheaper and cheaper every day, allowing researchers to have access to unprecedented parallelization degrees. Several topics are interlaced in these two requirements: (1) having the proper learning paradigms and knowledge representations, (2) understanding them and knowing when are they suitable for the problem at hand, (3) using efficiency enhancement techniques, and (4) transforming and visualizing the produced solutions to give back as much insight as possible to the domain experts are few of them. This tutorial will try to answer this question, following a roadmap that starts with the questions of what large means, and why large is a challenge for GBML methods. Afterwards, we will discuss different facets in which we can overcome this challenge: Efficiency enhancement techniques, representations able to cope with large dimensionality spaces, scalability of learning paradigms. We will also review a topic interlaced with all of them: how can we model the scalability of the components of our GBML systems to better engineer them to get the best performance out of them for large datasets. The roadmap continues with examples of real applications of GBML systems and finishes with an analysis of further directions.

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Data-intensive computing has positioned itself as a valuable programming paradigm to efficiently approach problems requiring processing very large volumes of data. This paper presents a pilot study about how to apply the data-intensive computing paradigm to evolutionary computation algorithms. Two representative cases (selectorecombinative genetic algorithms and estimation of distribution algorithms) are presented, analyzed, and discussed. This study shows that equivalent data-intensive computing evolutionary computation algorithms can be easily developed, providing robust and scalable algorithms for the multicore-computing era. Experimental results show how such algorithms scale with the number of available cores without further modification.

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A byproduct benefit of using probabilistic model-building genetic algorithms is the creation of cheap and accurate surrogate models. Learning classifier systems---and genetics-based machine learning in general---can greatly benefit from such surrogates which may replace the costly matching procedure of a rule against large data sets. In this paper we investigate the accuracy of such surrogate fitness functions when coupled with the probabilistic models evolved by the x-ary extended compact classifier system (xeCCS). To achieve such a goal, we show the need that the probabilistic models should be able to represent all the accurate basis functions required for creating an accurate surrogate. We also introduce a procedure to transform populations of rules based into dependency structure matrices (DSMs) which allows building accurate models of overlapping building blocks---a necessary condition to accurately estimate the fitness of the evolved rules.

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Cancer diagnosis is essentially a human task. Almost universally, the process requires the extraction of tissue (biopsy) and examination of its microstructure by a human. To improve diagnoses based on limited and inconsistent morphologic knowledge, a new approach has recently been proposed that uses molecular spectroscopic imaging to utilize microscopic chemical composition for diagnoses. In contrast to visible imaging, the approach results in very large data sets as each pixel contains the entire molecular vibrational spectroscopy data from all chemical species. Here, we propose data handling and analysis strategies to allow computer-based diagnosis of human prostate cancer by applying a novel genetics-based machine learning technique ({\tt NAX}). We apply this technique to demonstrate both fast learning and accurate classification that, additionally, scales well with parallelization. Preliminary results demonstrate that this approach can improve current clinical practice in diagnosing prostate cancer.

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