This publication list summarizes research publications from 2012 to 1999 by W.G.E.J. Schoonen and collaborators. The publications cover a range of topics including in vitro toxicity screening methods, mechanisms of toxicity, biomarker identification, and endocrine disrupting activities of compounds. Many publications involve the application of high-throughput and high-content screening assays using cell lines like HepG2, HeLa and CHO to study genotoxicity and cytotoxicity.

1. Publication list
2012
Schoonen, W.G.E.J., Stevenson, J.C.R., Westerink, W.M.A., and Horbach, G.J. (2012b). Cytotoxic effects of
110 reference compounds on rat H4IIE and human HepG2 hepatocytes. III Mechanistic assays on oxygen
consumption with MitoXpress and NAD(P)H production with Alamar BlueTM. Toxicol. In Vitro 26,
511-525.
2011
Boitier, E., Amberg, A., Barbié, V., Blichenberg, A., Brandenburg, A., Gmuender, H., Gruhler, A., McCarthy,
D., Meyer, K., Riefke, B., Raschke, M., Schoonen, W., Sieber, M., Suter, L., Thomas, C., and Sajot, N.
(2011). A comparative integrated transcript analysis and functional characterization of differential
mechanisms for induction of liver hypertrophy in the rat. Toxicol and Applied Pharmacol. 252:85-96.
Elferink, M.G.L., Olinga, P., Leeuwen, van E.M., Bauerschmidt, S., Polman, J., Schoonen, W.G., Heisterkamp,
S.H. and Groothuis, G.M.M. (2011). Gene expression analysis of precision cut human liver slices indicate
stable expression of ADME-TOX related genes. Toxicology and Applied Pharmacology 253:57-69.
Schoonen, W.G.E.J., Westerink, W.M.A., Water, van de F.M., and Horbach, G.J. (2011). High Content
Screening for in vitro toxicity testing. Eur. Pharmacol. Rev. 16:50-55.
Sonneveld, E., Pieterse B., Schoonen, W.G., and van der Burg, B. (2011). Validation of in vitro screening
models for progestagenic activities: Inter-assay comparison and correlation with in vivo activity in rabbits.
Toxicol In Vitro 25:545-554.
Westerink, W.M.A., Staalduinen, A.A., Polman, J., Horbach, G.J., and Schoonen, W.G.E.J. (2011a). The
identification of biomarkers for genotoxicity in HepG2 cells by transcriptomics. (Thesis Westerink).
Westerink, W.M.A., Schirris, T.J.J., Horbach, G.J., and Schoonen, W.G.E.J. (2011b). Development and
validation of a high content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells and effect
of the tumor suppressor p53 gene. Mut. Res. 724:7-21.
Water, van de F.M., Havinga, J., Ravesloot, W.T., Horbach, G.J.M.J., and Schoonen, W.G.E.J. (2011). High
Content Screening analysis of phospholipidosis: Validation of a 96-well assay for CHO-K1 and HepG2
cells for the prediction of in vivo based phospholipidosis. Toxicol. In Vitro 25, 1870-1882.
2010
Bovee, T.F.H., Thevis, M., Hamers, A.R.M., Peijnenburg, A.A.C.M., Nielen, M.W.F. and Schoonen, W.G.E.J.
(2010). SERMs and SARMs: their (anti)estrogenic and (anti)androgenic activities as determined in
biological screening assays with yeast and CHO cells. J. Steroid Biochem. Mol Biol. 118, 85-92.
Schoonen, W.G.E.J., Westerink, W.M.A., and G.J. Horbach (2010). Segregation of molecular mechanisms of
genotoxicity and carcinogenicity across human, yeast and Salmonella species. Eur Pharm. Rev. 15,45-50.
Schoonen, W.G.E.J., Westerink, W.M.A., Horbach, G.J. (2010). Application of Medium and HighThroughput
Screening for In Vitro Toxicology in the Pharmaceutical Industry. Alttox Website:
http://alttox.org/ttrc/overarching-challenges/way-forward/schoonen-westerink-horbach/.
Westerink, W.M.A., Stevenson J.C.R., Horbach G.J. and Schoonen W.G.E.J. (2010). The development of
RAD51C, Cystatin A, p53 and Nrf2 luciferase reporter assays in metabolic competent HepG2 cells for the
assessment of mechanistic genotoxicity and of oxidative stress in the early research phase. Mutation
Research / Genetic Toxicology and Environmental Mutagenesis 696,21-40.
2009
Benefenati, E., Benigni, R., DeMerani, D., Helma, C, Kirkland, K., Martin, T.M., Mazzatorta, P., Ouédraogo-
Arras, Richard, A., Schilter, B, Schoonen, W.G.E.J., Snyder, R., and Yang, C. (2009). Predictive models
for carcinogenicity and mutagenicity: frameworks, state-of-the-art and perspectives. Journal of
Environmental Science and Health, Part C 27: 1-34.
Schoonen, W.G.E.J., Westerink, W.M.A., and G.J. Horbach (2009a). High-throughput screening for the analysis
of in vitro toxicity. Molecular, Clinical and Environmental Toxicology (ed. Andreas Luch). Birkhäuser
Publishing, Basel, Switzerland. Volume 1 chp 14, 401-439.
Schoonen, W.G.E.J., Westerink, W.M.A., and G.J. Horbach (2009b). In vitro toxicology, als alternatief voor
dierproeven, in de farmaceutische industrie. Toxicologische Communicatie, Data enDocumentatie
(TCDD), Nieuwsbrief voor de Nederlandse Vereniging van Toxicologie, 1, 22-24.
Westerink, W.M.A., Stevenson J.C.R., Lauwens, A., Griffioen G., Horbach G.J. and Schoonen W.G.E.J.
(2009a). Evaluation of the VitotoxTM and RadarScreen assays for the rapid assessment of genotoxicity in
the early research phase of drug development. Mutation Research / Genetic Toxicology and Environmental
Mutagenesis 676, 113-130.

2. 2008
Bovee, T.F.H., Schoonen, W.G.E.J., Hamers, A.R.M., Bento, M.J. and Peijnenburg, A.A.C.M. (2008). Screening
of synthetic and plant-derived compounds for (anti-) estrogenic and (anti-)androgenic activities. Analytical
and Bioanalytical Chemistry 390, 1111-1119.
Elferink, M.G.L., Olinga, P., Draaisma, A.L., Merema, M.T., Bauerschmidt, S., Polman, J., Schoonen, W.G.,
and Groothuis, G.M.M. (2008). Microarray analysis in rat liver slices correctly predicts hepatotoxicity as
observed in. Toxicology and Applied Pharmacology 229: 300-309.
Kloosterboer, H.J., Schoonen, W.G.E.J., and Verheul, H.A.M. (2008). Proliferation of breast cells by steroid
hormones and their metabolites. In: Breast cancer prognosis, treatment and prevention. (Ed. J.R.
Pasqualini). Academic Press, New York, USA. Chp. 18, 343-386.
Schoonen, W.G.E.J., Westerink, W.M.A., and G.J. Horbach (2008). In vitro toxicity screening as pre-selection
tool. Eur. Pharm. Rev. 3: 40-44.
van den Bout-van den Beukel C.J.P., Hamza O.J.M., Moshi M.J., Matee M.I.N., Mikx F., Burger D.M.,
Koopmans P.P., Verweij P.E., Schoonen W.G.E.J. and van der Ven A.J.A.M. (2008). Evaluation of
cytotoxic, genotoxic and CYP450 competition effects of Tanzanian plant extracts traditionally used for
treatment of fungal infections. Basic & Clinical Pharmacology & Toxicology 102, 515-526.
Westerink, W.M.A., Stevenson J.C.R., and Schoonen W.G.E.J. (2008). Pharmacologic profiling of human and
rat cytochrome P450 1A1 and 1A2 induction and competition. Arch. Toxicol. 82: 909-921.
2007
Elferink M., Olinga P., Draaisma A., Merema M., Bauerschmidt S., Polman J., Schoonen W., and Groothuis G.
(2007). MicA microarray analysis of hepatotoxicity in vivo and in vitro. Toxicol. Lett. 172S, S77, T13.
Kruse, J.J.C.M., Svensson, J.P., Huigsloot M., Water van de B., Vrieling H., Giphart-Gassler, M., Polman, J.,
Schoonen, W.G.E.J., Horbach, S.J. (2007). A portrait of cisplatin-induced transcriptional changes in mouse
embryonic stem cells reveals a dominant p53-like response. Mutation research 617, 58-70.
Schoonen W.G.E.J., Smit M.J., Zandberg P., Horbach G.J.M.J., Ploemen J._P.H.T.M., Kloks C.P.A.M.,
Mellema J.R., Thijssen-van Zuylen C., Vogels J.T.W.E., Tas C.A. and van Nesselrooij J.H.J. (2007a).
Sensitivity of 1H NMR analysis of rat urine in relation to toxicometabonomics. Part I Dose dependent toxic
effects of bromobenzene and paracetamol. Tox. Sci. 98, 271-285.
Schoonen W.G.E.J., Smit M.J., Zandberg P., Horbach G.J.M.J., Ploemen J._P.H.T.M., Kloks C.P.A.M.,
Mellema J.R., Thijssen-van Zuylen C., Vogels J.T.W.E., Tas C.A. and van Nesselrooij J.H.J. (2007b). Tox.
Sci. Uniform procedure of 1H NMR analysis of rat urine and toxicometabonomics. Part II Comparison of
NMR profiles for classification of hepatotoxicity. Tox. Sci. 98, 286-297.
Westerink, W.M.A. and Schoonen, W.G.E.J. (2007a). Cytochrome P450 enzyme levels in HepG2 cells and
cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicology in vitro 21,
1581-1591.
Westerink, W.M.A. and Schoonen, W.G.E.J. (2007b). Phase II enzyme levels in HepG2 cells and cryopreserved
primary human hepatocytes and their induction in HepG2 cells. Toxicology in vitro 21, 1592-1602.
Westerink WMA, Stevenson JCR, Schoonen WGEJ (2007c) CYP1A induction and species differences between
human HepG2 and rat H4IIE cells. Toxicol. Lett. 172S, S98, T63.
2006
Schoonen. W., en Horbach J. (2006). In vitro toxicologie als alternatief voor het gebruik van proefdieren. In:
Kan het ook anders? Beschouwingen voor alternatieven voor dierproeven. Editors J.Swart, G. Groothuis, J.
Horbach en J. van der Valk. Uitgevreij DAMON bv, Budel, Nederland, pagina’s 70-79.
Solleveld E., Riteco J.A.C., Jansen H.J., Pieterse, B., Brouwer A., Schoonen W.G., and van der Burg B. (2006).
Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities. Tox. Sci. 89,
173-187.
2005
Schoonen W.G.E.J., Westerink W.M.A., de Roos J.A.D.M. and Débiton E. (2005). Cytotoxic effects of 100
reference compounds on Hep G2 and HeLa cells and of 60 compounds on ECC-1 and CHO cells. I
Mechanistic assays on ROS, glutathione depletion and calcein uptake. Toxicology in vitro 19: 505-516.
Schoonen W.G.E.J., Westerink W.M.A., de Roos J.A.D.M. and Débiton E. (2005). Cytotoxic effects of 110
reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II
Mechanistic assays on NAD(P)H, ATP and DNA contents. Toxicology in vitro 19: 491-503.

3. 2004
Peeters B.W.M.M., Tonnaer J.A.D.M., Groen M.B., Broekkamp C.L.E., van der Voort H.A.A., Schoonen
W.G.E.J., Smets R.J.M., Vanderheyden P.M.L., Gebhard R.,. Ruigt G.S.F. (2004). Glucocorticoid receptor
antagonists: new tool to investigate disorders characterized by cortisol hypersecretion. The International
Journal on the Biology of Stress 7: 233-241.
Buijsman R., Garritsen A., Gossen J., Klomp J., Kuil C, van Noort P., van Rijn R., Rovers G., Schoonen W.,
Sterrenburg J.G., Stock Th., Verdonk G., Visser A., van Boeckel S., Dijkema R., Hermkens P. (2004).
Identification of ligands for the orphan nuclear receptor gene. Med. Chem. Res. 13: 210-215.
2003
Gooyer de M.E.; Deckers G.H.; Schoonen W.G.E.J.; Verheul H.A.M.; Kloosterboer H.J. (2003). Receptor
profiling and endocrine interactions of tibolone. Steroids 68: 21-30.
2000
Casteren, J.I.J., Schoonen, W.G.E.J., and Kloosterboer, H.J. (2000). Development of time-resolved
immunofluorometric assays for rat follicle-stimulating hormone and luteinizing hormone and application
on sera of cycling rats. Biol. Reprod. 62: 886-894.
Deckers, G.H., Schoonen W.G.E.J., and Kloosterboer, H.J. (2000): Influence of the substitution of 11-
methylene, ∆15 , and/or 18-methyl groups in norethisterone on receptor binding, transactivation assays and
biological activities in animals. J. Steroid Biochem. Mol. Biol. 72: 83-92.
Schoonen W.G.E.J., Deckers, G., Gooijer, de M.E., Ries de R, and Kloosterboer, H.J. (2000): Hormonal
properties of nortehisterone, 7α-Methyl-Norethisterone and their derivatives. J. Steroid Biochem. Mol.
Biol. 74: 213-222.
Schoonen W.G.E.J., Deckers, G., Gooijer, de M.E., Ries de R, Mathijssen-Mommers, G., Hamersma, H., and
Kloosterboer, H.J. (2000): Contraceptive progestins: Various 11-substituents combined with four 17-
substituents: 17α-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene
lactones. J. Steroid Biochem. Mol. Biol. 74: 109-123.
Kloosterboer, H.J., Deckers, G.H., Schoonen, W.G.E.J., Hanssen, R.G.J.M., Rose, U.M., Verbost, P.M., Hsiu,
J.G., Williams, R.F., and Hodgen, G.D. (2000). Preclinical experience with two selective progesterone
receptor modulators on breast and endometrium. Steroids 65: 733-740.
1999
Schoonen W.G.E.J., Vermeulen, G.J., Deckers, G.H., Verbost, P.M. and Kloosterboer, H.J. (1999):
Antiprogestins: mechanism of action and in vitro and in vivo selection. Current Topics in Steroid Research
2: 15-54.
1998
Dijkema R., Schoonen W.G.E.J., Teuwen R., Struik van der E., Ries de R.J.H., Kar, S.A.T. and Olijve W.
(1998): Human progesterone receptor A and B isoforms in CHO cells I Stable transfection of receptor and
receptor-responsive reporter genes: transcription modulation by (anti)progestagens. J Steroid Biochem.
Molec. Biol. 64: 140-156.
Schoonen W.G.E.J., Dijkema R., Ries de R.J.H., Wagenaars, J.L., Joosten, J.W.H., de Gooyer, M.E., Deckers,
G.H. and Kloosterboer, H.J. (1998): Human progesterone receptor A and B isoforms in CHO cells II
Comparison of binding, transactivation and ED50 values of several synthetic (anti)progestagens in vitro in
CHO and MCF-7 cells and in vivo in rabbits and rats. J Steroid Biochem. Molec. Biol. 64: 157-170
Schoonen W.G.E.J., Ries de R.J.H., Joosten, J.W.H., Mathijssen-Mommers and Kloosterboer, H.J. (1998):
Development of a high throughput in vitro bioassay for the assessment of potencies of steroids for the
progesterone receptor with a luciferase reporter system in CHO cells. Anal. Biochem. 261: 222-224.
1997
Hakola K., Van der Boogaart P., Mulders J., de Leeuw R., Schoonen W., Heyst J.v., Swolfs A., Van Casteren J.,
Huhtaniemi I., Kloosterboer H. (1997): Recombinant rat follicle-stimulating hormone; production by
Chinese hamster ovary cells, purification and functional characterization. Molecular & Cellular
Endocrinology 127:59-69.
Hakola K., Boogaart P.v.d., Mulders J., Leeuw R. de, Schoonen W., Heyst J.v., Swolfs A., Casteren J.v.,
Huhtaniemi I., Kloosterboer H.J. (1997): Recombinant rat luteinizing hormone; production by Chinese
hamster ovary cells, purification and functional characterization. Molecular & Cellular Endocrinology 127:
47-56.
Gebhard R., Vandervoort, H., Schuts, W., and Schoonen, W. (1997): 11,21-bisphenyl-19-norpregnane
derivatives are selective antiglucocorticoids. Bioorganic & Medicinal Chemistry Letters 7: 2229-2234.

4. 1996
Rijks L.J., Boer G.J., Endert E., Bruin K. de, Bos J.C. van den, Doremalen P.A. van, Schoonen W.G., Janssen
T.G. and Royen E.A. van (1996): The stereoisomers of 17α-[123l] iodovinylestradiol and its 11ß-methoxy
derivative evaluated for their estrogen receptor binding in human MCF-7 cells and rat uterus, and
distribution in immature rats. Eur J Nucl Med (1996) 23:295-307
1995
Kloosterboer H.J., Deckers G.H., Gooyer M.E. de, Dijkema R., Orlemans E.O.M., Schoonen W.G.E.J. (1995):
Pharmacological properties of a new selective antiprogestagen: Org 33628. Annals New York Academy of
Sciences, vol 761: 192-201.
Schoonen W.G.E.J., Joosten J.W.H. and Kloosterboer H.J. (1995): Effects of two classes of progestagens,
pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells. I MCF-7 cell
lines. J. Steroid. Biochem. Molec. Biol. 55:423-437.
Schoonen W.G.E.J., Joosten J.W.H. and Kloosterboer H.J. (1995): Effects of two classes of progestagens,
pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells. II T47D cell
lines. J. Steroid. Biochem. Molec. Biol. 55: 439-444.
1994
Kloosterboer H.J., Deckers G. and Schoonen W. (1994): Pharmacology of two new very selective anti-
progrestagens: Org 31710 and Org 31806. Human Reproduction Volume 9, Suppl. 1, 47-52.
Kloosterboer H.J., Schoonen W.G.E.J., Deckers G.H. and Klijn J.G.M. (1994): Effects of progestagens and Org
OD14 in in vitro and in vivo tumor models. J. Steroid Biochem. Molec. Biol. 49, 311-318.
1992
Pruijn F.B., Schoonen, W.G.E.J., Joenje, H. (1992). Inactivation of mitochondrial metabolism by hyperoxia-
induced oxidative stress. Ann. New york Acad. Sci. 663, 453-455.
Slootweg M.C., Ederveen A.G.H., Schot L.P.C., Schoonen W.G.E.J. and Kloosterboer H.J. (1992): Estrogen and
progestagen synergistically stimulate osteoblast proliferation. J. Endocrinol. 133, R5-8.
Slootweg M.C., Ederveen A.G.H., Schot L.P.C., Schoonen W.G.E.J. and Kloosterboer H.J. (1992): Estrogen and
progestagen synergistically stimulate osteoblast proliferation. Obst Gyn Survey 47, 803.
1991
Schoonen, W.G.E.J., Wanamarta, A.H., Van der Klei-van Moorsel, J.M., Jacobs, C. and Joenje, H. (1991).
Characterisation of oxygen-resistant Chinese hamster ovary cells. III. Relative resistance of succinate and
α-ketoglutarate dehydrogenases to hyperoxic inactivation. Free Rad. Biol. Med. 10, 111-118.
1990
Joenje, H., Gille, J.J.P., Pasman, P., and Schoonen (1990). Oxygen poisoning as a model for accelerated cellular
aging. In: From gene to man. Gerontological research in The Netherlands. Eds. C.F.A. van Bezooijen, R.
Ravid and A.A.J. Verhofstad. pp 44-51. J.H. Pasmans Offsetdrukkerij B.V., ‘s-Gravenhage.
Schoonen, W.G.E.J., Wanamarta, A.H., Van der Klei-van Moorsel, J.M., Jacobs, C. and Joenje, H. (1990).
Respiratory failure and stimulation of glycolysis in Chinese hamster ovary cells exposed to normobaric
hyperoxia. J. Biol. Chem. 265, 11118-11124.
Schoonen, W.G.E.J., Wanamarta, A.H., Van der Klei-van Moorsel, J.M., Jacobs, C. and Joenje, H. (1990).
Hyperoxia-induced clonogenic killing of HeLa cells associated with respiratory failure and selective
inactivation of Krebs cycle enzymes. Mutation Research 237, 173-181.
1989
Borg, B., Schoonen, W.G.E.J. and Lambert, J.G.D. (1989). Steroid metabolism in the testes of the breeding and
non-breeding three-spined stickleback, Gasterosteus aculeatus. Gen. Comp. Endocrinol. 73, 40-45.
Keizer, H., Schuurhuis, G.J., Broxterman, H., Lankelma, J., Schoonen, W.G.E.J. and Joenje, H. (1989).
Correlation of multidrug resistance with decreased drug accumulation,
altered subcellular drug distribution, and increased P-glycoprotein expression in cultured SW-1573 human
lung tumor cells. Cancer Res. 49, 2988-2993.
Resink, J.W., Schoonen, W.G.E.J., Albers, P.C.H., Filé, D.M., Notenboom, C.D., Van den Hurk, R., and van
oordt, P.G.W.J. (1989). The chemical nature of sex attracting pheromones from the seminal vesicle of the
African catfish, Clarias gariepinus. Aquaculture, 83, 137-151.

5. Schoonen, W.G.E.J., Granneman, J.C.M. and Lambert, J.G.D. (1989). Steroids and steroid glucuronides in the
ovarian fluid of the African catfish Clarias gariepinus between ovulation and oviposition. Fish Physiol.
Biochem. 6, 91-112.
Schoonen, W.G.E.J., Lambert, J.G.D., Penders, M.T., Van Roosmalen, M.E., Van den Hurk, R., Goos, H.J.Th.
and Van Oordt, P.G.W.J. (1989). Steroidogenesis during induced oocyte maturation and ovulation in the
African catfish, Clarias gariepinus. Fish Physiol. Biochem. 6, 61-78.
Van Dam, G.H., Schoonen, W.G.E.J., Lambert, J.G.D. and Van Oordt, P.G.W.J. (1989). Plasma profiles of
fourteen ovarian steroids before, during and after ovulation in African catfish, Clarias gariepinus,
determined by gas chromatography and mass spectrometry. Fish Physiol. Biochem. 6, 79-89.
Wanamarta, A.H., Schoonen, W.G.E.J., and Joenje H. (1989). Hyperoxia-induced disturbance of energy
metabolism in HeLa cells due to inactivation of mitochondrial enzymes. Symposium on: Free radicals and
cancer. 8-9 december 1989 (poster), Tübingen, Germany.
1988
Schoonen, W.G.E.J., Lambert, J.G.D. and Van Oordt, P.G.W.J. (1988). Quantitative analysis of steroids and
steroid glucuronides in seminal vesicle fluid of feral spawning and feral and cultivated non-spawning
African catfish, Clarias gariepinus. Gen. Comp. Endocrinol. 70, 91-100.
Schoonen, W.G.E.J., Penders, M.T., Van Dam, G.H. and Lambert, J.G.D. (1988). 5ß-Pregnane-3α,6α,17α,20ß-
tetrol and 5ß-pregnane-3α,6α,17α-triol-20-one: steroids of ovarian origin in the African catfish, Clarias
gariepinus, during oocyte maturation. Gen. Comp. Endocrinol. 69, 181-188.
1987
Ali, S.A., Schoonen, W.G.E.J., Lambert, J.G.D., Van den Hurk, R. and Van Oordt, P.G.W.J. (1987). The skin
of the male African catfish, Clarias gariepinus, a source of steroid glucuronides. Gen. Comp. Endocrinol.
66, 415-424.
Borg, B., Timmers, R.J.M., Schoonen, W.G.E.J., Lambert, J.G.D. and Van Oordt, P.G.W.J. (1987). Testes and
brain steroid metabolism in the three-spined stickleback, Gasterosteus aculeatus. Gen. Comp. Endocrinol.
66, 41.
Penders, M.T., Schoonen, W.G.E.J. and Lambert, J.G.D. (1987). Steroidogenesis in the ovary of the African
catfish, Clarias gariepinus, before, during and after an induced ovulation. Neth. J. Zool. 37, 442-443.
Resink, J.W., Schoonen, W.G.E.J., Van den Hurk, R., Viveen, W.J.A.R. and Lambert, J.G.D. (1987). Seasonal
changes in steroid metabolism in the male reproductive organ-system of the African catfish, Clarias
gariepinus. Aquaculture, 63, 59-76.
Schoonen, W.G.E.J., Granneman, J.C.M., Lambert, J.G.D. and Van Oordt, P.G.W.J. (1987). Steroidogenesis in
the testes and seminal vesicles of spawning and non-spawning African catfish, Clarias gariepinus.
Aquaculture 63, 77-88.
Schoonen, W.G.E.J., Granneman, J.C.M., Lambert, J.G.D., Viveen, W.J.A.R. and Van Oordt, P.G.W.J. (1987).
A quantitative study of steroid bioconversion in the seminal vesicles of the African catfish Clarias
gariepinus (Burchell), under natural spawning and non-spawning conditions and under fish farm
conditions. Comp. Biochem. Physiol. 87B, 687-695.
Schoonen, W.G.E.J. and Lambert, J.G.D. (1987). GC-MS analysis of steroids and steroid glucuronides in the
seminal vesicle fluid of the African catfish, Clarias gariepinus. Gen. Comp. Endocrinol. 68, 375-386.
Schoonen, W.G.E.J., Lambert, J.G.D., Penders, M.T., Van Roosmalen, M.W., Van den Hurk, R., De Leeuw, R.
and Van Oordt, P.G.W.J. (1987). Effect of pimozide-LHRHa injection on steroidogenesis in the ovaria of
the African catfish, Clarias gariepinus. Gen. Comp. Endocrinol. 66, 21.
Schoonen, W.G.E.J., Lambert, J.G.D., Resink, J.W., Viveen, W.J.A.R. and Van Oordt, P.G.W.J. (1987). A
quantitative study of steroid bioconversions in the testes of the African catfish, Clarias gariepinus
(Burchell), under natural spawning and natural and cultivated non-spawning conditions. J. Endocr. 112,
323-332.
Schoonen, W.G.E.J., Van Bennekum, A.M., Lambert, J.G.D., Viveen, W.J.A.R. and Van Oordt, P.G.W.J.
(1987). Steroidogenesis in pre- and postspawned ovaries of feral African catfish, Clarias gariepinus.
Aquaculture, 63, 129-142.
Schoonen, W.G.E.J. (1987). Analysis of steroid synthesis in the reproductive organs of the African catfish,
Clarias Gariepinus. A basis for the study of sex pheromones.
Ph. D. Thesis, Tessel Offset, Utrecht, The Netherlands.
Van den Hurk, R., Schoonen, W.G.E.J., Van Zoelen, G.A. and Lambert, J.G.D. (1987).
The biosynthesis of steroid glucuronides in the testis of zebrafish, Brachydanio rerio, and their pheromonal
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