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Unit 1: Introduction to P&A,[object Object],Anatomy & Physiology,[object Object],	A.  Anatomy - “structure” (morphology),[object Object],			1.Definition:  branch of science that ,[object Object],			deals with the structure of body parts.,[object Object],	B.  Physiology – “function”,[object Object],			1.Definition:  branch of science that 			deals with the function of body 				parts.,[object Object]
	C.  Structure & function always relate,[object Object],			1.Example:  Arteries have very,[object Object],			muscular walls to adequately ,[object Object],			pump blood to all parts of body.,[object Object]
Homeostasis,[object Object],		A.  Defintion:  The tendency of the 			body to maintain a constant 			internal environment.,[object Object],		B.  In order to survive, the body		     needs to remain at homeostasis.,[object Object],		C.  Homeostasis is regulated by 		     body systems.,[object Object]
		1.  Negative Feedback,[object Object],a.Definition:  A system which 			maintains deviations in a				normal range.,[object Object],a.Example:  Blood pressure-				If blood pressure goes up,				negative feedback slows				heart to return it to normal.,[object Object]
		2.  Positive Feedback,[object Object],a.Definition:  A system which 			encourages deviations from 				normal ranges (homeostasis),[object Object],a.Example: Labor during 				pregnancy. The woman’s body is 			taken farther from normal 				(homeostasis) to achieve a goal.,[object Object]
Body Organization  (Humans are organized    					 in levels),[object Object],		A.  Cell,[object Object],Defintion:  basic structural and 			functional unit of life.,[object Object],Example:	 Skin cell	,[object Object],		B.  Tissue,[object Object],Definition:   a group of cells 				working together to perform a 			function. 			,[object Object],Example:  Epithelial tissue,[object Object]
	C.  Organ,[object Object],Definition:  A group of tissues 			working together to perform a 			special function.,[object Object],Example:  Skin,[object Object],	D.  Organ System,[object Object],Definition:  A group of organs 			working together to perform a 			special function,[object Object],Example:  Integumentary,[object Object]
E.  Organism,[object Object],Definition:  A group of organ 			systems working together to 			perform a function.,[object Object],Example:  Human body,[object Object]
Human Organ Systems,[object Object],	A.  Skeletal System,[object Object],		1.  Structure:  bones, ligaments, 		    tendons, cartilage, joints,[object Object],		2.  Function:  Support and 	  	  	     movement,[object Object],	B.  Muscular System,[object Object],		1.  Structure:  Muscles,[object Object],		2.  Function:  Movement, posture, 	     heat production,[object Object]
	C,[object Object],	C.  Integumentary System,[object Object],		1.  Structure:  Skin, hair, nails, 			    sweat glands, oil glands.,[object Object],		2.  Function:  Protection, 				    temperature regulation, 				    synthesize (make) certain body 		    products (Vitamin D),[object Object]
	D.  Digestive System,[object Object],		1.  Structure:  ,[object Object],		Digestive tract:  mouth, 				esophagus, stomach, intestines,[object Object],Accessory organs:  tongue, 				salivary glands, pancreas, liver,[object Object],		2.  Function:  mechanical and 			chemical digestion, absorb 				nutrients, eliminate wastes,[object Object]
E.  Respiratory System,[object Object],		1.  Structure:  Lungs, nasal cavity, 		   pharynx, larynx, trachea, bronchi,[object Object],		2.  Function:  Exchange of gasses 			   (CO2 & O2between blood and air.,[object Object],	F.  Cardiovascular System/Circulatory,[object Object],		1.  Structure:  Heart, arteries, 			    veins, capillaries, blood,[object Object],		2.  Function:  Transport nutrients, 		     waste, gasses, hormones,[object Object]
	G.  Nervous System,[object Object],		1.  Structure:  Brain, spinal cord, 			    nerves, sensory receptors,[object Object],		2.  Function:  Regulate all body 			    functions, detect sensation, 			    control movement,[object Object]
	H.  Endocrine System	,[object Object],		1.  Structure:  Endocrine glands:  			    pituitary, thyroid, adrenal, etc.; 		    hormones,[object Object],		2.  Function:  Regulates metabolism, 		    reproduction and other body 			    functions.,[object Object]
	I.  Urinary System,[object Object],		1.  Structure:  Kidneys, bladder, 			    ureters, urethra,[object Object],		2.  Function:  Removal of waste from 		   circulatory system; regulate blood 		    pH, ion content, water content,[object Object]
	J.  Lymphatic System,[object Object],		1.  Structure:  Lymph vessels, lymph 		   nodes, lymph, spleen, thymus gland,[object Object],		2.  Function:  Removal of foreign 			    substances in blood, combat 			    disease, fat absorption,[object Object],	K.  Reproductive System,[object Object],		1.  Structure:  Gonads, accessory 			    structures, and genitals,[object Object],		2.  Function: Process of 					    reproduction of life.,[object Object]
Anatomical Terminology,[object Object],    A.  Position Terms,[object Object],		1.  Superior – “above”,[object Object],		     -- Head superior to neck,[object Object],		2.  Inferior – “below”,[object Object],		     -- Tibia inferior to femur,[object Object],	    3.  Anterior/Ventral – “front/belly-	 	     side”,[object Object],		4.  Posterior/Dorsal – “back”,[object Object]
	5.  Medial – “toward midline”,[object Object],		-- shoulder medial to elbow,[object Object],	6.  Lateral – “away from midline”,[object Object],	7.  Proximal – “closer to point of 		  	     attachment”,[object Object],		-- elbow proximal to wrist,[object Object],	8. Distal – “further from point of 	  	    attachment”,[object Object],	9.  Superficial – “near surface”,[object Object]
	10.  Deep – “more internal”,[object Object],	11.  Articulate – “to meet”,[object Object],		-- The femur articulates with the 		    fibia,[object Object]
	B.  Body Sections/Cuts/Planes,[object Object],		1.  Sagittal,[object Object],			--lengthwise cut at midline,[object Object],		2.  Transverse,[object Object],			--divides body in superior and 			   inferior portions,[object Object],		3.  Frontal/Coronal,[object Object],			--Divides body in anterior and,[object Object],			   posterior portions,[object Object]
P&A - Units 1 & 2
	C.  Body Regions of the Abdomen,[object Object],		1.  Epigastric,[object Object],			(Middle Upper),[object Object],		2.  L/R Hypochondriac ,[object Object],			(Upper L/R),[object Object],		3.  Umbilical,[object Object],			(Middle),[object Object]
4.  L/R Lumbar,[object Object],			(Middle L/R),[object Object],		5.  Hypogastric,[object Object],			(Low middle),[object Object],		6.  L/R Iliac,[object Object],			(L/R low),[object Object]
P&A - Units 1 & 2
	D.  Body (Major) Cavities,[object Object],		1.  Cranial Cavity,[object Object],			-- nasal cavity,[object Object],			-- oral cavity,[object Object],			-- cranial cavity,[object Object],2. Vertebral Cavity,[object Object],	-- spinal cavity,[object Object],		2.  Thoracic Cavity ,[object Object],			-- rib cage,[object Object],			-- diaphragm,[object Object]
		3.  Abdominopelvic Cavity,[object Object],			-- stomach,[object Object],			-- pelvis,[object Object],			-- bladder,[object Object],			-- Split into abdominal and ,[object Object],pelvic cavities,[object Object]
	E.  Body Membranes,[object Object],		1.  Pleural Membranes (lungs),[object Object],			a.  Visceral pleural (organ),[object Object],			--membrane portion 					   covering organ,[object Object],			c. Pleural cavity – area 					surrounding organ,[object Object],				- filled with fluid,[object Object],			b.  Parietal pleural,[object Object],			--membrane portion attached 			   to body wall lining cavity,[object Object]
P&A - Units 1 & 2
2.  Pericardial Membranes (heart),[object Object],			a.  Visceral pericardium,[object Object],			--membrane covering heart 				   itself,[object Object],			b.  Parietal percardium,[object Object],			--membrane outside visceral,[object Object],			   pericardium,[object Object]
		3.  Peritoneal Membranes - abdomen,[object Object],			a.  Visceral peritoneum,[object Object],			--membrane surrounding organs,[object Object],			b.  Parietal peritoneum,[object Object],			--membrane attachment to 				  cavity wall,[object Object]
Chemistry of Life,[object Object],	A.  Atomic Structure,[object Object],		1.  Nucleus,[object Object],			--most massive,[object Object],			--houses proton  and neutron,[object Object],		2. Proton,[object Object],-- (+) Positive charged,[object Object],		3.  Neutrons,[object Object],			--Neutral ,[object Object]
	4.  Electrons,[object Object],		--(-) charged,[object Object],		--located in energy level shells/ 			clouds around nucleus,[object Object],	5.  Energy levels,[object Object],		--levels/orbits around nucleus that 		hold e- of certain energy,[object Object],		--each level holds specific number  		of e-  (1:2, 2:8, 3:18),[object Object]
	6.  Proton & electron # = in balanced 	  	    elements,[object Object],	7.  Neutron # = mass number – atomic 	    number,[object Object],	8.  Mass # = proton # + neutron #,[object Object],	9.  Atomic # = proton #,[object Object]
10.  Ion,[object Object],Definition:  Element that has lost 		or gained e- and therefore 				received a charge.,[object Object],a. Importantto body,[object Object],Example:Ca+ = bones, teeth, blood,[object Object],				 clotting.,[object Object],Fe+:  Red blood cell ,[object Object],				 function/formation,[object Object]
	B.  Chemical Bonding,[object Object],		1.  Ionic Binding,[object Object],Definition:  Occurs when atoms 			gain or lose e- becoming 				opposite charged and attract,[object Object],Example:  NaCl,[object Object],		2.  Covalent Bonding,[object Object],Definition:  Occurs when two or 			more atoms share electrons,[object Object],Example:  H2O,[object Object]
	C.  Chemical Reactions,[object Object],		1.  Synthesis – “build up”,[object Object],		--combining atoms – growth, repair,[object Object],			A + B – AB,[object Object],		2.  Decomposition – “break down”,[object Object],		--molecules break apart – food,[object Object],		   digestion,[object Object],			AB – A + B,[object Object]
		3.  Exchange,[object Object],			--Decomposition + Synthesis,[object Object],			   AB + CD -– AC + BD,[object Object],		4.  Reversible,[object Object],			--End product may return to 			   reactants,[object Object],			   A + B 	AB,[object Object]
	D.  Acid & Bases,[object Object],		1.  Electrolytes,[object Object],Definition:   Substances that 			release ions in water and therefore 		conduct electricity.,[object Object],		2.  Acids,[object Object],		--Electrolytes that release H+ 			into water,[object Object],		--pH:  0-6.9,[object Object],		-- red on litmus,[object Object]
	3.  Bases,[object Object],		--Electrolytes that release OH- 			into water,[object Object],		--pH:  7.1-14,[object Object],		--Blue on litmus,[object Object]
	E.  Major Body Organic Substances,[object Object],		1.  Carbohydrates,[object Object],Structure:  Small to large molecules 		of C, H + O  (in ratio, Ch2O),[object Object],Function:  Provide energy for body,[object Object],		a.  Monosaccharides – simple sugar 		   (glucose, fructose, galactose),[object Object],		b.  Disaccharides – two simple sugars 		    (sucrose, lactose),[object Object],		c.  Polysaccharides – complex sugars		    (glycogen),[object Object]
2.  Lipids,[object Object],Structure:  Substances that do not 		dissolve in H2O, mainly C, H, O 			(includes fats, phospholipids, 			steroids),[object Object],Function:,[object Object],	Fats: Break down for energy ,[object Object],phosopholipids:  make cell 				membranes                                            ,[object Object],steroids:  regulate body process     		example:  male/female,[object Object]
		a.  Glycerols + fatty acid = FAT,[object Object],example:  triglycerols= 3 			  glycerols + a fatty acid,[object Object],	3.  Proteins,[object Object],Structure:  Molecules of C, H, O, N,[object Object],	    -- Amino Acids:  Building block of 			protein,[object Object],Function:  regulate chemical reactions,[object Object],		--energy sources,[object Object],		--cell synthesis/make up cytoplasm,[object Object],		--protect from disease (antibodies),[object Object],		--serve as enzymes,[object Object],		** Watch Lamina video,[object Object]
a.  Hydrogen bonds,[object Object],		-- hold coil together,[object Object],		-- bonds may break by exposure 			   to access:,[object Object],			*heat,[object Object],			*radiation,[object Object],			*chemicals,[object Object]
Denatured Protein:  protein with 	hydrogen bonds broken or uncoiled due 	to environmental factors.  (example:  	heat),[object Object],*** EGG EXAMPLE,[object Object],	4.  Nucleic Acids,[object Object],Structure:  Large complex 				molecules of C, H, O, N, P,[object Object],		--RNA, DNA,[object Object],		--Nucleotide:  building block of 			nucleic acid,[object Object]
Function:  --control cellular activities,[object Object],		         --synthesize proteins (RNA),[object Object],			 --pass on genetic information,[object Object]
Cellular Transport,[object Object], 		*In order for the body to maintain 	homeostasis, chemicals/substances/ions 	constantly pass through cell membranes.,[object Object],	A.  Passive Transport,[object Object],		1.  Defintion:  Movement of substances 	     across cell membrane from HIGH                 	     concentration to LOW concentration 	     requiring no energy,[object Object]
2.  Types,[object Object],		a.  Diffusion: movement of 				    substances from high to low 			    concentration,[object Object],example:   O2 from air diffuse into 		blood and CO2 to air,[object Object],		b.  Facilitated Diffusion:  diffusion 		     with aid of a carrier molecule in 		     cell membrane “bussers”,[object Object],example:  glucose into cells,[object Object]
C. Osmosis: movement of WATER ,[object Object],across membrane from high 				to low concentration,[object Object],		1. cells need EXACTLY right 					amount of watery 						environment or they will 				shrink/swell,[object Object]
Types of Osmosis,[object Object],1. Hypertonic – Hyper=more,[object Object],	a. More water than needed in the 		cell, so net water LEAVES cell to 			reach homeostasis,[object Object],	b. cell then SHRINKS,[object Object],2. Hypotonic – Hypo=less,[object Object],	a. Less water than needed in the 			cell, so water ENTERS cell to 			reach homeostasis,[object Object],	b. cell then SWELLS,[object Object],3. Isotonic,[object Object],	a. Homeostasis is reached,[object Object]
		d. Filtration,[object Object],		1. movement of substances 				across cell membrane due to 			pressure,[object Object],		2. ex: blood pressure forces 				water out of capillaries but 				proteins are left in.,[object Object]
B. Active transport,[object Object],	1. Movement of substances across 			membrane from LOW to HIGH 				REQUIRING ENERGY!!,[object Object],	2. Types:,[object Object],		a. Pumps – carrier molecules 				push ions low to high,[object Object],			1. Na/K pumps in cells,[object Object],		b. Endocytosis – engulfing of 				particles by cells,[object Object],			1. pinocytosis – takes in 					liquids,[object Object],			2. phagocytosis – take in 					solids,[object Object],				a. ex:Phagocytes:engulf 					bacteria,[object Object]

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