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AUTOTRANSPLANTATION OF THE 
RECURRENTLY PROLAPSED THIRD EYELID 
GLAND IN DOGS 
Dr. Felipe Wouk 
Dr. João Alfredo Kleiner
PROLAPSE OF THE GLAND 
• “Cherry-eye” 
• Most common primary disorder of 
the nictitating membrane 
• Generally before 2 years of age 
• Weakness in the connective tissue
PROLAPSE OF THE GLAND 
• Predisposition in: 
• American Cocker Spaniel 
• Lhasa Apso 
• Pekingese 
• Beagle 
• English Bulldogs 
• Cane Corso
PROLAPSE OF THE GLAND 
• Surgical replacement of the gland is 
indicated (Helper et al, 1974; Chang & Lin, 1980) 
• Several procedures 
• Anchor 
• Pocket 
• Lower incidence of KCS than dogs 
not treated and those where the 
gland is excised. 
(Morgan et al, 1993)
• Recurrence of third eyelid gland 
prolapse after surgery occurs in 
5 - 10 % of cases. 
• Re-operation is not always 
possible and have a lower 
success rate.
OBJECTIVES 
• Evaluation of the clinical effects of autotransplantation of 
part of the third eyelid gland into the conjunctival fornix 
• Alternative means of maintaining the harmony of the 
preocular tear film 
• Gland produces 30 to 50% of the aqueous part of the 
precorneal tear film.
METHODS 
• 8 dogs (different breeds) 
• Presenting with recurrent prolapsed gland of the third 
eyelid 
• Complete ophthalmic exam prior and 3 months after the 
autotransplant
SURGICAL TECHNIQUE 
• Excision of the third eyelid gland 
• Graft preparation using the middle 1/3 portion of the 
excised gland 
• Construction of a pocket within the superior temporal 
conjunctival fornix 
• Suturing using 6-0 vicryl
RESULTS 
• Conjunctival hyperemia resolved in 98 % of the cases. 
• Corneal Neovascularization and Blepharospasm 
resolved in 100 % of the cases. 
• Corneal Luster restored in 99 %.
SCHIRMER TEAR TEST (STT) 
56.3 % increasing in STT !!
Before the surgery 90 days after the procedure
CONCLUSIONS 
• The prolapsed third eyelid gland have a very low function 
because of the inflammation 
• When you replace it, the gland starts to work well again 
• The same happen with the autotransplantation.
CONCLUSIONS 
• All patients showed clinical improvement following surgery. 
• Technique is quite easy to perform. 
• Appears to be an alternative option in cases of recurrence 
after surgical replacement of the third eyelid lacrimal gland.
ACKNOWLEDGMENTS: 
Dr. Felipe Wouk Dr. Akihiko Saito
Any Questions ? ? ?

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Autotransplantation of the recurrently prolapsed third eyelid gland in dogs

  • 1.
  • 2. AUTOTRANSPLANTATION OF THE RECURRENTLY PROLAPSED THIRD EYELID GLAND IN DOGS Dr. Felipe Wouk Dr. João Alfredo Kleiner
  • 3. PROLAPSE OF THE GLAND • “Cherry-eye” • Most common primary disorder of the nictitating membrane • Generally before 2 years of age • Weakness in the connective tissue
  • 4. PROLAPSE OF THE GLAND • Predisposition in: • American Cocker Spaniel • Lhasa Apso • Pekingese • Beagle • English Bulldogs • Cane Corso
  • 5. PROLAPSE OF THE GLAND • Surgical replacement of the gland is indicated (Helper et al, 1974; Chang & Lin, 1980) • Several procedures • Anchor • Pocket • Lower incidence of KCS than dogs not treated and those where the gland is excised. (Morgan et al, 1993)
  • 6. • Recurrence of third eyelid gland prolapse after surgery occurs in 5 - 10 % of cases. • Re-operation is not always possible and have a lower success rate.
  • 7. OBJECTIVES • Evaluation of the clinical effects of autotransplantation of part of the third eyelid gland into the conjunctival fornix • Alternative means of maintaining the harmony of the preocular tear film • Gland produces 30 to 50% of the aqueous part of the precorneal tear film.
  • 8. METHODS • 8 dogs (different breeds) • Presenting with recurrent prolapsed gland of the third eyelid • Complete ophthalmic exam prior and 3 months after the autotransplant
  • 9. SURGICAL TECHNIQUE • Excision of the third eyelid gland • Graft preparation using the middle 1/3 portion of the excised gland • Construction of a pocket within the superior temporal conjunctival fornix • Suturing using 6-0 vicryl
  • 10. RESULTS • Conjunctival hyperemia resolved in 98 % of the cases. • Corneal Neovascularization and Blepharospasm resolved in 100 % of the cases. • Corneal Luster restored in 99 %.
  • 11. SCHIRMER TEAR TEST (STT) 56.3 % increasing in STT !!
  • 12. Before the surgery 90 days after the procedure
  • 13. CONCLUSIONS • The prolapsed third eyelid gland have a very low function because of the inflammation • When you replace it, the gland starts to work well again • The same happen with the autotransplantation.
  • 14. CONCLUSIONS • All patients showed clinical improvement following surgery. • Technique is quite easy to perform. • Appears to be an alternative option in cases of recurrence after surgical replacement of the third eyelid lacrimal gland.
  • 15. ACKNOWLEDGMENTS: Dr. Felipe Wouk Dr. Akihiko Saito