1. 18-May-11
When Medicine meets Engineering Bertram Neville Brockhouse
Improving safety in the operating room and beyond
1918 – 2003
Guy Dumont 1994 Nobel Prize in
and Physics
Mark Ansermino
Departments of Electrical and Computer Engineering and
Anesthesiology, Pharmacology & Therapeutics, NSERC Prize for Interdisciplinary Research in Science and Engineering
The University of British Columbia, Vancouver, Canada.
Thank You Chronology
• NSERC for awarding us the 2010 • 1999: Initial contacts
Brockhouse Canada Prize • 2000: Work in sensing and control starts
• NSERC and CIHR for supporting our work • 2002: Peter Wall Institute of Advanced
over the years Studies Exploratory Workshop on
• UBC FFaculties of A li d S i
l i f Applied Science and of
d f Automation and Robotics in the OR
Medicine • 2002: GD-MA collaboration starts
• Departments of Electrical & Computer • 2003: Founding of ECEM
Engineering and of Anesthesiology,
Pharmacology & Therapeutics
Funding via NSERC/CIHR
CHRP Grants
• 2003-05: Online monitoring of physiological
parameters
• 2005-07:Tactile display of physiological
monitoring
• 2008 10 Cl
2008-10: Closed-loop control of anesthesia
d l l f h i
• 2011-13:The phone oximeter
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2. 18-May-11
Delivery of FastanII main backing store for the 418/III. Capacity 132MB.
London Hospital 1970
2

3. 18-May-11
• Information
overdose
• Limits to
human
vigilance
• Complexity
Trend Detection
Change Matters ??
Detecting physiological trend changes
Meet IAN: The Intelligent Anesthesia
Navigator Trend Detection
Patient-adapted change detection
3

4. 18-May-11
Trend Detection iAssist in the OR
Vibrotactile Display Vibrotactile Display
Vibrotactile Display
4

5. 18-May-11
Automation
Modern Anesthesia
Closed-Loop Control of Intravenous
The Anesthesia Process Anesthesia
5

6. 18-May-11
Control of Neuromuscular Blockade Monitoring of Cortical Activity
Clinical Tests Monitoring of Nociception
• Pupillometry
• SPI based on heart rate and plethysmograph
• Heart rate variability (HF/LF)
• Respiratory sinus arrhythmia (RSA)
6

7. 18-May-11
Portable Anesthesia Control System
Global Health The mHealth Revolution
The Phone Oximeter iPleth Block Diagram
Pleth
Nonin RR extraction
Sensor Xpod
interface SpO2+HR
RR
Decision OpenGL
Support Engine Engine
User Input Interface
smartphone
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8. 18-May-11
Global Applications
• In Burundi (pop 8M):
• Two anesthesiologists
• Thirty-four anesthesia nurses
• One closed-circuit anesthesia machine
The lung is a WINDOW to the body Infant Pneumonia (ALRI)
Two million deaths a year
Why do they die? Infant Pneumonia
No Treatment
Inappropriate treatment
Inadequate treatment
Simple Treatments!
8

9. 18-May-11
Neonatal Infection SpO2 will change the world!
Impact
Early diagnosis (screening)
Lay health worker diagnosis
Follow response to antibiotics
Reduced antibiotic use
Early referral
Manage oxygen therapy
One million a year die
Technology for Healthy
Living
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