Akutni Koronarni Sindrom

AKUTNI KORONARNI SINDROM Irena Šubjak Tonći Božin

Definicija ,[object Object],[object Object],[object Object]

Akutni koronarni sindrom Ischemic Discomfort Unstable Symptoms No ST-segment elevation ST-segment elevation Unstable Non-Q Q-Wave angina AMI AMI ECG Acute Reperfusion History Physical Exam

Epidemiologija ,[object Object],[object Object],[object Object]

Normalna stijenka žile Tunica adventitia Tunica media Tunica intima Endothelium Subendothelial connective tissue Internal elastic membrane Smooth muscle cells Elastic/collagen fibers External elastic membrane

Razvoj ateroma Normal Fatty streak Lipid-rich plaque Lipid core Fibrous cap Foam cells Thrombus

Patogeneza ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Vulnerable vs Stable Atherosclerotic Plaques Lumen Fibrous Cap Lipid Core Lipid Core Fibrous Cap Lumen Vulnerable Plaque Stable Plaque ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Libby P. Circulation . 1995;91:2844-2850.

Patogeneza ,[object Object],[object Object],[object Object],[object Object]

Patogeneza ,[object Object],[object Object],[object Object]

Patogeneza ,[object Object],[object Object],[object Object],[object Object],[object Object]

Klinička slika ,[object Object],[object Object],[object Object]

Klinička slika ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Dijagnostiči postupak ,[object Object],[object Object],[object Object],[object Object]

Dijagnostiči postupak ,[object Object],[object Object],[object Object]

Liječenje ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Liječenje ,[object Object],[object Object],[object Object],[object Object],[object Object]

Liječenje ,[object Object],[object Object],[object Object],[object Object]

Akutni Koronarni Sindrom

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